Lopedium

Description overdue on 07/29/2014

• Latin name: Lopedium
• ATC code: A07DA03
• Active substance: Loperamide (Loperamide)
• Manufacturer: Pharma GmbH Salyutas, Germany

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Lopedium, instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Synonyms
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

One tablet contains loperamide hydrochloride   - 2 mg.

Additional ingredients: talc, lactose monohydrate, magnesium stearate, corn starch, gelatin, E172, titanium dioxide E131 .

Product form

Oval capsules, half gray and half green. Inside - a homogeneous white powder. Packages 10, 20, 30 or 50 pieces.

Pharmacological action

From what Lopedium? The drug has the ability to suppress peristalsis   intestine. Renders antidiarrhoeal action .

Pharmacodynamics and pharmacokinetics

Loperamide   - A synthetic derivative piperidine . It acts on the   peripheral opioid receptors Reducing the production acetylcholine   and prostaglandins . Thus, it occurs decline propulsive motility   small intestine, bowel movements occur less frequently, and feces becomes more solid consistency.

Indications for use of the drug are frequent bouts of diarrhea. This is due to the ability to raise funds tone anal sphincter , Reduce the incidence of defecations.

After taking the pills, they quickly get into the blood after absorption in GI . After 4-5 hours after ingestion, loperamide reaches its maximum concentration in blood plasma and, still quite small amounts, can penetrate through blood-brain barrier .

Undergoes reaction metabolism in the liver, is output from 9-14 hours stool, small quantity - through the kidneys.

Due to the fact that the drug metabolized   the liver is required to consult a doctor and a dose adjustment for patients with liver disease.

Indications

The drug can be assigned from any species diarrhea .

Lopedium - from what these pills?

• treatment chronic, allergic, emotional, medical   and ray   diarrhea;
• additional agent for the treatment of infectious diseases GI   (together with antibiotics );
• diarrhea caused by a change of diet, disturbances in metabolism, certain diseases   ZHTK ;
• elimination of diarrhea at ileostomy .

Tablets Lopedium - from what else?

The indications for use of the drug can also be indigestion tourists ( traveler's diarrhea ). The capsules can be administered for two days. In the case of blood in the stool should consult a doctor.

Contraindications

• strong allergic reactions   on the components of the drug;
• acute dysentery   (blood in the stool, fever);
• the age of six;
• bacterial enterocolitis   ( salmonellosis, shigellosis );
• sharp colitis Drug-induced antibiotics ;
• in the application of funds occurs abdominal distention . constipation . ileus .

Side effects

FEATURES:

• headache, tremor, somnolence   and loss of consciousness ;
• urinary retention, cramps ;
• constipation, nausea, indigestion, megacolon;
• Stevens-Johnson syndrome . angioedema , Itching on the skin and hives .

Lopedium, instructions for use (method and dosage)

The capsules are taken as a whole, do not bite through, washed down with water.

According to the instructions for use Lopedium, it can be administered to adults and children starting at age six.

For adults with chronic or acute diarrhea, the initial dose is 4 mg, after each trip to the toilet (defecation). Thereafter, the dosage can be reduced to 2 mg. Lots of drug taken per day - 16 mg.

For children initially administered 2 mg, max - 6 mg per day.

The treatment ends to achieve a state where the time between the two acts of defecation is not less than 12 hours.

Overdose

Symptoms of an overdose of a powerful depression CNS Including urinary retention, ileus , Severe depression CNS . stupor . corestenoma . convulsions . Keep in mind that children are more sensitive to the drug than adults.

Naloxone   - Specific antidote   drug. You may need to re-introduction of an antidote. Do not worth to exclude and symptomatic therapy, gastric lavage, reception enterosorbents .

Cooperation

It is not necessary to combine the drug with other drugs depressing the central nervous system.

Precautions to take P-glycoprotein inhibitors ( quinidine, ritonavir ) CYP3A4 inhibitors ( Gemfibrozil ) AND trakonazolom . The D esmopressinom . K etokonazolom .

Terms of sale

The presence of a prescription is not required.

Storage conditions

In the dark, reach of children, at a temperature of 30 degrees set out above.

Shelf life

5 years.

Analogs

Match code ATC 4th level:

• Loperamide

The closest analogues: A oflatil, Usara .

Synonyms

Synonyms of the drug are: AND modium, Stoperan loperamide hydrochloride, loperamide .

During pregnancy and lactation

Admission medications during pregnancy and during breast-feeding is not recommended. Should see a doctor, who in turn podbreet another suitable drug.

Reviews about the Lopedium

Reviews on the forums good. All those who took the drug, happy with the result, the drug is rapidly and effectively cope with the delicate problem of frequent trips to the toilet. At times to patients was enough one-two receptions, to lead chair in the norm. Another advantage is considered a low cost, as compared with its analogues. However, there are sporadic cases of allergy to the active substance or side effects.

Price Lopedium where to buy

Price Lopedium is about 40 rubles per 10 tablets.

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