Nifuroxazide

Description overdue on 05/29/2014

• Latin name: Nifuroxazide
• ATC code: A07AX03
• Active substance: Nifuroxazide (Nifuroxazide)
• Manufacturer: Gedeon Richter Romania, S.A. (Romania); Warsaw FZ Ternopharm of (Poland); Jurabek Laboratories Ltd (Uzbekistan)

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions on nifuroxazide
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• For children
• Newborns
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

One tablet Nifuroxazide   It contains the active substance: nifuroxazide   - 100 mg (Richter nifuroxazide in tablet form, has an identical composition).

Excipients: gelatin, starch, talc, magnesium stearate, silica colloidal anhydrous .

The composition of the shell: titanium dioxide, polyethylene glycol, hydroxypropylmethyl cellulose , Quinoline yellow dye, talc .

In 100 grams of suspension Nifuroxazide Richter   It contains the active substance: nifuroxazide   - 4 grams.

Excipients: sodium hydroxide, sucrose, carboxy polymethylene, citric acid monohydrate, methyl parahydroxybenzoate, antifoaming emulsion , Banana flavor, purified water.

Product form

Tablets yellow, biconcave, round and smooth, without any damage or stains are coated shell. 24 pieces in a blister. 1 blister in a cardboard box.

The suspension (syrup, as it is sometimes called) of a yellow color, with a sweet taste and smell of banana. Available in bottles of 90 ml (with measuring spoon); 1 bottle in a cardboard package.

Pharmacological action

The drug has bactericidal   and antibakterialnoym   action.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The drug has antibacterial   activity and for the treatment of infectious diseases of the digestive tract. Inhibits the activity of enzymes dehydrogenases   and inhibits production of the protein in the cells of bacteria. It weakens the synthesis of toxins by microorganisms.

Affects Gram-positive microorganisms : Staphylococcus spp. ; Gram-negative enterobacteria : Salmonella spp., Klebsiella spp., Escherichia coli, Enterobacter spp., Citrobacter spp., Shigella spp., Proteus spp., Yersinia spp.

No effect on the normal flora of the gastrointestinal tract, without provoking dysbiosis . It is not conducive to the emergence of resistant strains.

The drug has no systemic effects on the body and does not alter blood parameters.

Pharmacokinetics

After taking the drug is not absorbed in the intestine, creating a significant concentration of the active substance in the digestive tract, and soon enough exhibits therapeutic effect. Excreted in the feces.

Indications

• Diarrhea   (chronic and acute), caused by Gram-positive   ( streptococci   and staphylococci ) And some Gram   ( Shigella, Escherichia coli, Klebsiella, Salmonella ) Bacteria.
• Diarrhea   after Antibiotic Changes the normal bacterial flora of the colon.
• Diarrhea   at appendicitis , Food poisoning, autoimmune chronic gastritis .
• Toxic diarrhea   (pathogens - Gram-negative bacteria   ( Salmonella, Klebsiella, Shigella, Escherichia coli ) In children aged 2 months.

Contraindications

• Allergies   to the drug or any of its components.
• Age up to 2 months.

Side effects

Rarely - nausea, stomach pain.

Individual sensitivity to the drug: skin rash, shortness of breath, itching (required drug discontinuation and symptomatic treatment).

Instructions on nifuroxazide

Instructions for use Nifuroxazide (tablets)   and instruction on suspension Nifuroxazide Richter (syrup)   They point out that the drug is used inside the mouth.

Receive Mode suspension : For children from 2 to 6 months, the recommended dose - 2, 5-5 ml twice a day, from 6 months to 6 years - 5 ml three times a day (8 hours). Children from 6 years and adults - 5 ml every 6 hours.

Pills   Nifuroxazide recommended for adults and children from 6 years to 2 tablets four times a day for 6 days.

Overdose

Overdose cases are not fixed.

Cooperation

Do not use the drug at the same time sorbents   and an alcohol.

Terms of sale

In Ukraine, drug prescription in Russia - without a prescription.

Storage conditions

Keep away from children. Store at temperatures up to 25 degrees, in a dark place.

Shelf life

Two years.

Cautions

In the case of symptoms of dehydration is necessary to conduct rehydration therapy   in addition to standard drug therapy.

Analogs nifuroxazide

Match code ATC 4th level:

• Ersefuril
• Stopdiar
• Entoban

Known analogues of the drug: Enterofuril   (Bosnia and Herzegovina), Nifurozid-Health   (Ukraine) Lekor (Ukraine) Ersefuril   (France).

For children

Note allows for the possibility of using the syrup for children between the ages of 2 months. Suspension for children from 2 to 6 months of 2.5-5 mL taken twice a day; 6 months and older - 5 ml three times a day.

Newborns

Prohibited use of the drug in infants up to 1 month and preterm infants.

With alcohol

At the time of treatment should abandon admission alcohol.

During pregnancy and lactation

Use with caution.

Reviews nifuroxazide

Reviews nifuroxazide show a sufficiently high therapeutic effect of the drug in the majority of cases when used as indicated. Reported side effects are rare.

Nifuroxazide - an antibiotic or not?

The drug is a derivative of nitrofuran. It belongs to the group of antimicrobials ( antibiotics ).

Is it better or nifuroxazide Enterofuril?

Nifuroxazide (nifuroxazide Richter) and Enterofuril are complete analogues, their price is approximately comparable. Reviews of preparations do not allow to give preference to any of them. However Enterofuril has a greater variety of forms-release tablets on the number in the package (№8, 16 and 30) and dosing (100 and 200 mg). Using the tablets in a dosage of 200 mg of the more convenient and can reduce the dosing frequency of the drug twice.

Price nifuroxazide

In Ukraine, the price Nifuroxazide Richter tablets   (№24) will cost 53, 5 hryvnia, and the price suspension for children   It will be about 81 hryvnia. In Russia, the price of the drug in the form of tablets - 330 rubles, in the form of syrup - 500 rubles.

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Legalon

Description overdue on 08/31/2014

• Latin name: Legalon70, Legalon 140
• ATC code: A05BA03
• Active substance: Milk Thistle fruit extract (Silybi mariani fructuum extract)
• Manufacturer: Madaus (Germany)

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• Composition
• Product form
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications legalon
• Contraindications
• Side effects
• Legalon - Instructions for use
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Reviews
• Price, where to buy

Composition

• Legalon 70 1 capsule contains the active ingredient - dry extract of milk thistle fruits 86.5-93.35 mg, which corresponds to a content of 70 mg silymarin ; Excipients - povidone .   polysorbate 80 . mannitol . sodium carboxymethyl starch . magnesium stearate ; Capsule composition: gelatin, red oxide, titanium dioxide, sodium lauryl sulfate, black oxide.
• 1 capsule contains 173-188 Legalon 140, 7 mg   dry extract of milk thistle fruits , Which corresponds to 140 mg silymarin ; auxiliary substances and the composition of the capsule such as a capsule 70 Legalon.

Form release Legalon 70

• Solid gelatine capsules brown in 10 capsules in blister; in a cardboard bundle by 2, 3 or 6 blister (20, 30 or 60 capsules);
• pills 20 pills in a blister pack in a cardboard box.

Form release Legalon 140

• Solid gelatine capsules brown 10 capsules in blister; in a cardboard bundle 2, 3 or 6 blister (20, 30 or 60 capsules).

Pharmacological action

The product has the following pharmacological effects:

• hepatoprotective   - Protects the liver cells (hepatocytes) from destruction and toxic effects;
• regenerative   - Contributes to the regeneration of liver cells;
• detoxification   - It clears liver toxins, including free radicals (antioxidant effect);
• anti-inflammatory   - Inhibits inflammatory processes in the liver.

Pharmacodynamics and pharmacokinetics

Legalon - a herbal preparation, the active ingredient in it is a dry extract of milk thistle. The included fruit extract of milk thistle silymarin   - Is a vegetable Antioxidant   complex has a healthy effect on the liver. The milk thistle found a lot of biologically active substances, including several species silymarin   and isomer silymarin silibinin Providing hepatoprotective effect.

Action   silymarin   and its isomers based on their antioxidant properties. They inhibit lipid peroxidation, thus preventing the destruction of the membranes (membrane) of hepatocytes. Silymarin   promotes restoration of hepatocytes by enhancing the action of intracellular enzymes. It stimulates the formation of intracellular proteins and phospholipids, which are major components of cell membranes. Strengthening the membrane contributes to the preservation and rapid recovery of hepatocytes.

Silymarin   Prevent entry into hepatocytes some hepatotoxic poisons, such as poison mushroom pale toadstool. Furthermore, suppresses the formation of silymarin prostaglandins   - The main components of the inflammatory process, ie, has inflammatory action .

Recovery of cellular metabolism contribute contained in milk thistle fruit tocopherols, minerals (potassium, magnesium, copper, selenium), unsaturated fatty acid. Last actively promote oxidation cholesterol That prevents the spread of atherosclerosis .
Biologically active substances of milk thistle fruits also have positive effects on the gastrointestinal tract, the digestive processes and education bile .

After treatment Legalon   in patients with liver disease improves the general condition, including their less worried about weakness, pain in the right upper quadrant ,, vomiting, pruritus, appetite disorders, etc. At the same time improving and laboratory findings that say about the state of the liver.

Set the entire process of promotion legalon in humans is impossible, because it contains too many biologically active substances. But found that after administration Legalon   inside, its concentration in plasma reaches a maximum within half an hour.

The bulk of the drug is excreted in bile   in the form of metabolic products. Maximum excretion in the bile is reached after 2 hours. As a result of interaction with the intestinal microflora evolved with almost half of the bile silymarin   again absorbed in the intestine, forming the enterohepatic circulation.

Indications legalon

The drug is prescribed in the following diseases and conditions:

• after infectious or toxic hepatitis to, hepatic injury;
• at toxic (including alcohol), and drug-induced liver;
• chronic hepatitis   any origin;
• while the exchange-dystrophic diseases of the liver, including, when fat hepatosis ;
• at cirrhosis - Long-term use legalon slows the progression of cirrhosis;
• in diseases of the bile ducts and gall bladder of any origin;
• chronic   pancreatitis   and after acute pancreatitis;
• in disorders of fat metabolism, hyperlipoproteinemia and atherosclerosis   - Long-term use legalon inhibits the spread of these violations;

Contraindications for use legalon

Hypersensitivity to the drug

Side effects legalon

The drug is well tolerated. Because of side effects known to only a small legalon laxative effect Which is quite rare.

Legalon - Instructions for use

Capsules and pills taken by mouth, swallowed whole with water. Admission legalon not associate with eating. The dosage of the drug, the multiplicity of its reception during the day, the duration of treatment is determined by the attending physician, depending on the condition and age of the patient.

Instructions on Legalon 70 : Drug take 1 - 2 capsules twice or thrice a day. In the long course of treatment is sufficient to take the drug twice a day. Babies Depending on the age and general condition prescribed by half or one capsule three times a day. In the long course of treatment is sufficient to take the drug twice a day, at the same dosage.

Instructions for use Legalon 140 : Drug taking 1 capsule twice or thrice a day. In the long course of treatment is sufficient to take the drug twice a day.
The standard course of treatment - not less than 12 weeks, but can last several months.

Legalon Interaction with other drugs

The drug is perfectly combined with other drugs. But there is evidence that it is an antagonist of certain drugs, e.g., Yohimbine   (a treatment for Impotence ) And F entolamina (preparation of groups blockers expanding peripheral blood vessels).

Terms of sale

The drug is released at a pharmacy without a prescription.

Storage conditions

Capsules and pills should be stored in a dark place at a temperature no higher than 30 ° C. The drug should not be accessible to children.

Shelf life

5 years

Analogs

Match code ATC 4th level:

• Enerliv
• Laennek
• Progepar
• Antral
• Potassium Orotate
• Hepa-Merz
• Glutargin
• Phosphogliv
• Galstena
• Karsil
• Essentiale

Analogs - a variety of dosage formulations groups which are used to treat the same disease. Legalon belongs to the hepatic - drugs protects and restores the liver cells. He has many counterparts, both vegetable and animal, synthetic origin. There are also homeopathic remedies with hepatoprotective properties:

• vegetable hepatoprotectors - Apkosul, Liv 52;
• hepatoprotectors animal origin -   Syrepar Erbisol ;
• hepatoprotectors, which include essential phospholipids - Livolin forte, polyols, Liping, lipophile, Essentiale;
• hepatoprotectors containing amino acids - Ademetionine, Gepasteril B Glutargin, lecithin, methionine, ornithine, Tsitrarginin;
• synthetic hepatoprotectors - Antral, ziksorin, Thiotriazoline ;
• homeopathic hepatoprotectors - Galstena, Hepar compositum Hepel, Hall-Grand .

Available as a set of synonyms legalon - drugs, the active ingredient of which is a fruit extract of milk thistle. It CARS Geparsil, Leprotek, Naturkarsevt, Natursil, Silegon, Silibinin, Silibor, Silimar, Silymarin, Siromin.

Combined hepatoprotectors, which include milk thistle and other vegetable components: Gepabene, Gepatofalk plantations, Gepatovet and etc.

Reviews legalon

Reviews of this preparation mostly positive: long-term use consistently improves the condition of patients.   Reviews on Legalon 140   It indicates that a large dose of the drug in most cases justified. Reviews of doctors all positive - the drug is effective as a part of complex treatment and as monotherapy.

Negative reviews   about this drug is very small. But if you go to the forum, you can find them. Mostly negative feedback due to the fact that when taking legalon no immediate therapeutic effect. Indeed, this herbal product, so it acts slowly.

Price legalon

Legalon price depends on the number of capsules in the package. Prices in Moscow are different:

• Price Legalon 70, 20 units-from 183 to 208 rubles;
• Price Legalon 70, 30 pcs. - From 245 to 272 rubles;
• Price Legalon 70, 60 pcs. - From 385 to 477 rubles;
• Legalon price 140, 20 pieces - from 310 to 314 rubles;
• Price Legalon 140, 30 pcs. - From 320 to 399 rubles;
• Price Legalon 140, 60 pcs. - From 550 to 698 rubles.

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Ebermin

Description overdue on 07/08/2014

• Latin name: Ebermin
• ATC code: D06BA51
• Active substance: Recombinant human growth factors and silver sulfadiazine
• Manufacturer: Heber Biotec (Cuba)

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

100 g of ointment contains active ingredients:

• recombinant human epidermal growth factor origin   - 1 mg;
• silver sulfadiazine - 1 year

As auxiliary substances of a pharmaceutical preparation are:

• stearic acid   - 18 g;
• glycerol - 5 g;
• Potassium carbonate - 500 mg;
• methyl parahydroxybenzoate - 180 mg;
• Propyl - 20 mg;
• Purified water - 100 g

Product form

Ebermin ointment for external use - a homogeneous mass of white, close to the consistency of cream, soft structure with a weak but characteristic odor. Packaged the drug in plastic bottles of 30 or 200, the carton pack can hold 1 bottle.

Pharmacological action

The drug Ebermin - integrated pharmaceutical having wound healing and antiseptic . One of the main active ingredients of the drug is human growth factor Which is a highly purified peptide epidermal origin. It is produced by genetically modified yeast strain type Saccharomyces Cerevisiae Derived using recombinant deoxyribonucleic acid. According to the mechanism of action is a pharmaceutical preparation is identical physiological factors of human growth produced by the body normally.

This component has a stimulating effect on migration fibroblasts , Progenitor cells connective tissue . keratinocytes and Endothelial cells Systems whose action is implemented to intensify the healing of skin defects. Restores the elasticity of the tissue, scarring and activates the processes of epithelialization of the defect and underlying tissue structures (formed by stable and high-quality granulation zone ).

Silver sulfadiazine , Other active drug component, has a strong antiseptic properties against a broad spectrum of microorganisms. It exerts its antimicrobial effect in the fight against Gram-positive and Gram-negative bacteria, Candida species Everywhere inhabiting on the skin, and dermatophytes .

Hydrophilic base   Ebermin ointments and auxiliary substances are dehydrating effect That is output from the pathological nidus wound excess water. Thus, greatly reduces pain, and maintain the necessary therapeutic concentration of the active constituent components becomes easier task.

It is worth emphasizing that the pharmaceutical preparation is also a strong cosmetic effect . Through integrated action elements ointment to normal orientation and aging collagen fibers, warned pathological scarring phase, which provides aesthetic appearance the reconstructed skin defect. Particularly noticeable data properties of the drug, if used after chickenpox. Characteristic, sometimes disfiguring traces of the disease come to naught, leaving behind such adverse effects.

Pharmacodynamics and pharmacokinetics

Medicinal ointment is used topically. When applied to a pharmaceutical formulation to intact skin or wound defects active constituent components are not absorbed into the systemic circulation, and therefore does not have a cure for generalized effects.

Indications

• nezatyagivayuschiesya long and scars;
• superficial or deep skin burns   and subcutaneous tissue of varying degrees of severity;
• sores   any origin (including those that have appeared as a result of the progression of chronic venous insufficiency, Diabetes . obliterating endarteritis . erysipelas   pathologies and many others);
• surgical or cosmetic intervention, associated with violation of the integrity of the skin;
• bedsores ;
• frostbite ;
• during autodermoplasty (transplantation of their own area of ​​the skin of the patient) in the areas of lysis, or transplantation of donor skin;
• cytostatic ulcers   (the origin of which is related to the use of pharmaceuticals group cytostatics );
• radiotherapy (radiation) dermatitis ;
• conducting surface Radiotherapy .

Contraindications

• individual sensitivity, inherited or acquired intolerance to the ingredients of the drug;
• an area with confirmed active tumor process   (even in the case of benign oncogenic development);
• Zone surgical excision;
• pregnancy ;
• period breast-feeding ;
• Children under age 1.

Precautions pharmaceutical preparation can be used in the following pathologies:

• kidney or liver failure;
• deficit glucose-6-phosphate dehydrogenase .

Side effects

As a rule, medication Hebermin pharmaceutical product is well tolerated, with no adverse effects of therapy. In rare cases, may experience the following adverse effects:

• allergic reactions   (component in the sulfa drug) - local redness, itching, rash;
• a burning sensation or discomfort in the area of ​​application of ointment;
• the contraction of the skin at the site of treatment;
• local pain.

Instructions for use (method and dosage)

The drug can be used in all stages of healing wound healing process .

Before applying the pharmaceutical preparation should be carried out standard   debridement   wounds with abundant use of antiseptic broad spectrum. Next, after drying the wound surface, a layer of ointment is applied 1-2 mm. As a rule, the closed method of treatment is placed on top of a sterile cloth or occlusive film coating. The latter method is used for healing skin defect in a humid environment. You can also use a special atraumatic mesh cover   for burns I-III degrees.

The dosage of the drug depends on the type of wound healing and the treatment strategy selected. If the selection of pathological secrets abundant, it is recommended that one application of ointment per day. If exudation is moderate or even the meager level, you can use Ebermin 1 every 2 days. With bespovyazochnoy therapy   (healing wound defects without bandaging after applying ointment) The amount of medication increases of applications to 1-3 per day.

Before each application of ointment Ebermin should be mandatory Toilet wounds Removing dead skin cells and other abnormal wound separation of the hearth. To do this, use a sterile isotonic sodium chloride solution   or a solution of a broad-spectrum preservatives. The procedure should be carried out very carefully so as not to damage the image under the ointment of granulation tissue and epithelial layers growing.

Conservative treatment lasts as long as possible to close the wound surface skin graft through plastic surgery.

Therapies Radiation   or radiation dermatitis   It is somewhat different. The ointment is applied on the irradiated skin area with a thin layer of 1 mm within 6-8 hours after irradiation. The drug is used during the whole period of radiotherapy pharmaceuticals daily.

Overdose

Drug overdose cases in the medical literature is not described.

Cooperation

Incompatibility or adverse clinical interaction in the process of conservative therapy pharmaceutical preparation with any drugs is observed.

Terms of sale

Dispense medication only certified by the attending physician prescription.

Storage conditions

Hebermin should be protected from direct light and reach of young children a place at a constant temperature of 15-25 degrees Celsius.

Shelf life

2 years.

Cautions

In some wounds, traumatic injuries and defects of the skin use open method of therapy That is in the process of rehabilitation is not conservative bandage covering the problem area. In such a case, you should avoid direct sunlight on the site of application of medicinal ointments, as ultraviolet radiation   may cause irreversible changes in the structure of the active ingredients of the pharmaceutical preparation.

In long-term course of medication or extensive burn surfaces may develop leukopenia . thrombocytopenia and eosinophilia Because it is recommended for regular diagnostic blood tests for the early detection of quantitative changes in the composition of blood.

Analogs Ebermina

Match code ATC 4th level:

• Argosulfan

Ebermin - this is the first drug, the active component of which is   recombinant human growth factor   epidermal origin, obtained by genetic engineering techniques. Because ointments are analogs number pharmaceuticals similar therapeutic effect, which includes the following medications: Aekol . Vundehil .   Calendula ointment . Livian . Panthenol .

Babies

In pediatric practice, the pharmaceutical preparation may be used for children older than 1 year.

During pregnancy and lactation

Ebermina therapeutic effects have not been studied properly during pregnancy and lactation, because the use of the pharmaceutical in the conservative treatment is not advisable. In the case of indications for therapy with this drug the doctor should determine the relationship between the risk of adverse effects and the benefits and then decide to use the drug.

Reviews on Ebermin

Reviews of topical ointment on Internet resources and beauty forums exclusively positive character, which is not surprising, since the pharmaceutical preparation is unique in its kind. The use of genetically modified strains of fungi and the reconstructed epidermal growth factor opens up the boundaries of the use of the drug. Ebermin allows not only to heal the deep wound surface and burns, even the most severe, but also to restore the damaged structure of the underlying tissues and organs.

Most reviews characterizes the pharmaceutical formulation as a cosmetic agent, which allows to eliminate the disfiguring consequences chickenpox . After a course of conservative treatment of scars take a more aesthetic appearance, epiteliziruyutsya more intensively, which hides them from the naked human eye. Moreover, organized collagen fiber orientation and fiber structure, that is, is more complete therapeutic effect on the damaged area of ​​the skin.

Price Ebermina where to buy

Buy ointment Ebermin in Russia is difficult, since the pharmaceutical preparation is found not in all pharmacy. For example, in St. Petersburg, there are only a few points of sale of the drug, carry out delivery of ointment only after reliable confirmation of the order.

When asked where to buy Ebermin in Moscow, the answer is somewhat easier, since some pharmacies offer to buy medicinal ointment for 400 rubles (the price of a small plastic bottle with a pharmaceutical product), or 2,000 rubles (large capacity).

Because most profitable way out of the situation for the citizens of Russia will be the purchase of medicinal ointments in the so-called online pharmacies on the Internet. Order Ebermin you can make the right search query and fill in some of the items of the questionnaire. As a rule, delivery of pharmaceutical products is carried to the threshold of the house, that is, to buy the ointment does not even need to get out of their own apartments.

Purchase of medicines in Ukraine is as difficult as in the Russian Federation. Price Ebermin ointments in the drugstores of the State begins with a minimum limit of 240 hryvnia per 30-gram bottle and ending with terrible figures of 700 hryvnia per 200-gram container of the drug.

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Slabilen

Description overdue on 09/25/2014

• Latin name: Slabilen
• ATC code: A06AB08
• Active substance: Picosulphate Sodium (Sodium picosulfate)
• Manufacturer: Lance-Pharm (Russia)

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Slabilen (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The drops contain sodium picosulphate .

Product form

The drops in the vial, intended for oral administration.

Pharmacological action

The drug is laxative.

Pharmacodynamics and pharmacokinetics

Slabilen has a laxative effect. Once in the body, it is hydrolyzed with the formation of the active form. The drug stimulates receptors irritation intestinal mucosa and increased its peristalsis .

After oral drops are not absorbed   from the gastrointestinal tract. They are not susceptible intestinal and hepatic circulation .

Indications

The tool is used for constipation Which are caused by hypotension   and weak colon peristalsis . proctitis And the need to normalize the chair at hemorrhoids . anal fissures . In addition, it is used in preparation for surgery, X-ray and instrumental studies.

Contraindications

Contraindications for use of this drug are: acute inflammatory diseases of the abdominal cavity, ileus , Abdominal pain of unknown origin, uterine bleeding . spastic constipation First trimester pregnancy Hypersensitivity to the components of the drug, incarcerated hernia . peritonitis , Bleeding from the gastrointestinal tract, cystitis , Children's age (up to 4 years), weight dehydration .

Side effects

When used Slabilen may appear weakness . hypotension . seizures .   abdominal   pain, as well as diarrhea Which may cause excessive loss of fluid and electrolytes.

Instructions for use Slabilen (method and dosage)

If there are no contraindications, and there is a need to take a drop Slabilen, instructions for use recommend it before bedtime Washed down with some liquid. Adults and children from 10 years old may use 10 to 20 drops orally. It is necessary to closely monitor the effect. If needed, the dosage is corrected.

Instructions for use Slabilen also reports that children should be given 5-10 drops. Duration - not longer than 10 days.

Overdose

Before the drug in doses in excess of the side effects may be increased. If overdose is chronic, there may be secondary hyperaldosteronism Defeat renal tubules . ischemia   colon.

As the treatment prescribed gastric lavage, correction fluid and electrolyte balance, antispasmodics .

Cooperation

With the combination of this drug with antibiotics   a wide range of possible reduction of laxative effect. When taken with diuretics . GCS   It may increase the likelihood of electrolyte imbalance.

If there was a reception Slabilen electrolyte imbalance may worsen tolerance   cardiac glycosides .

Terms of sale

The drug is sold without a prescription.

Storage conditions

Keep the medication you need in a well-protected against the penetration of sunlight. Optimum temperature - 20 ° C.

Shelf life

The drug is stored no longer than 3 years.

During pregnancy (and lactation)

In pregnancy, the drug is used only on strict conditions. In this case, the drug should be prescribed by a doctor. To combine the drug with breastfeeding impossible. It must be stopped, if necessary to take Slabilen.

Reviews Slabilene

Drops Slabilen get mostly positive reviews. Patients say that the drug has no taste, and because it is easy to take. It is an effective laxative.

Those who leave reviews about Slabilene also often wonder whether it is possible to use the drug during pregnancy. Doctors, however, clearly indicate that it should be done only if the potential benefit to the mother more likely risk to the fetus.

Among the possible disadvantages of the reviews referred to Slabilene inconvenience of dosing and the probability of occurrence of pain in the first days of admission.

Price Slabilen where to buy

Price Slabilen, on average, is 90 rubles. In some pharmacies, however, the cost may be somewhat higher. Thus, the price Slabilen and sometimes reaches 120 rubles.

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Exercises for the pelvic decide "male" problem

Suffering from chronic premature ejaculation men help to cope with this problem exercises for the pelvic floor muscles. Such the conclusion reached by researchers from Sapienza University in Rome.

premature ejaculation

A total of 12 weeks of regular exercises for the pelvic floor muscles enough to get rid of the problem premature ejaculation . which poisons the intimate lives of millions of men. Italian scientists led with Dr. Antonio Pastore away 40 victims of the disorder at the age of 19 to 46 years. All male ejaculation occurs within minutes after the start sex.

All volunteers at this time have tried different methods treatment, including creams, psychotherapy, antidepressants and various medicines, but none of them has had a noticeable impact. 12 weeks Volunteers performed exercises for the pelvic floor muscles   under the direction of instructors. At the end of the experiment, all the participants reported how much time they now extends from the beginning of sex and orgasm.

If the rate of physical activity to the mean time to orgasm in men was 31, 7 seconds after a course of exercises it has grown to 146, 2 seconds, ie it quadrupled. Rose and confidence in all volunteers, which is important.

Thus, exercises for the pelvic floor can be called one of the most effective ways to eliminate problems Premature Ejaculation .

However, the authors of the study emphasize that the experiment affected a small number of men, and to confirm his findings require more large-scale experiment. (READ MORE)

Sex

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Ice cream with Viagra to make sex a review

British confectioners created ice cream with Viagra and taste of champagne. Each batch contained 25 mg active substance that exactly half the recommended dose.

Viagra

The most popular tool for erectile dysfunction used to perceive the world in the form of small blue pills, and few people come to mind that Viagra   maybe delicious. But the British confectionery company Lick Me I'm Delicious firing special order ice cream with taste of champagne, which includes the famous drug. Creator of this delicacy became Charlie Harry Francis, who decided that one portion of his ice cream will contain 25 mg Viagra.

Viagra

It should be noted that the market for tablets Viagra   It can be purchased with an active compound content of 25 mg, 50 mg and 100 mg, but the recommended dose is 50 mg it. Francis said that to the creation of such an unusual delicacy prompted his celebrity, which is not very I like to drink tablets. Iceman has spent a few days at improving recipe by special order, but no details report did not.

"In this case the observed privacy - says Francis. - We signed an agreement on Privacy, and I can not mention the name of my client. I just allowed to announce that the ice cream was manufactured for the parties, and that all were very happy with the end result and the fact that I made "necessary the amount of "stuff".

We note that the London of The Icecreamists, once released the breast milk ice cream under the name "Lady Gaga" already long period of time produces a delicacy Sex Bomb, which includes herbal stimulants erection. But Francis and his colleagues began to establish the world's first flammable ice cream. (READ MORE)

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It revealed the secret of unsightly virtual sex

US scientists have found the ugly truth sexting - half of all sexual send texts deceitful nature. It turns out, fans of virtual sex is not always They wear the clothes and perform the actions reported by partners.

virtual sex

Sexting   (from Eng. sexting) It called forwarding personal photos, messages, intimate content through modern means of communication: cell phones, e-mail, social Internet networks. He gained huge popularity in recent years, and many Young people began to hold regular sessions virtual sex   between themselves, sending each other messages of an intimate nature with descriptions of what they Now dressed, what actions make with your body, and what would have wanted from partner.

According to the survey of 155 students American colleges, like every other message is false. AND Young people do not always take off their clothes or perform other action, they report to the partner during virtual sex . The data studies were published journal Computers in Human Behavior, and each its participants, who admitted in a lie, the scientists at the end of the conversation asked why he was lying.

Two-thirds of respondents reported that they were going to lie to please partners and one-third to make it pleasure. This woman during sexting   lie twice more often than men, which is comparable with statistics about imitation orgasms.

"Women were significantly more likely Men imitate orgasm, for obvious reasons, and more frequently depict desire, than experiencing it, - said study author Michel Drouin. - Women are a lie to please partners more frequently than men do. "(Read More)

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