- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Allokin-Alpha (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
1 vial of the drug contains 1 mg alloferon .
Product form
The pharmaceutical preparation is supplied to pharmacies as a lyophilized powder for solution for subcutaneous injection, placed in ampoules of 1 mg each. The vials were fixed in the tape contour cell package of polymeric materials for 5 or 10 pieces. The set also features ampoule knife in one piece. The carton generally comprises 2 to 5 blister ampoules or 1 10.
Pharmacological action
Allokin Alpha - a pharmaceutical preparation, which belongs to a group of antiviral agents. The drug active against viruses Flu . Hepatitis C and AT A first and a second type of virus Herpes . Human Papillomavirus (a drug also suppresses oncogenic strains This kind of microorganisms).
Biologically active substances, acting as an effective component is alloferon - Oligopeptide that stimulates the production of endogenous interferon and activating fractions a system of natural killer (natural killers). Also component contributes to the identification and destruction of damaged and not functioning cells by cytotoxic species lymphocytes .
Pharmacodynamics and pharmacokinetics
Allokin-alfa is used for subcutaneous injection, after which it quickly penetrates into the systemic circulation and interacts with immunocompetent cells . During clinical studies it was found that metabolites of the active component of the pharmaceutical preparation are similar in structure to the structural protein of blood plasma because the time to reach maximum concentration, it is difficult to set the level.
Within two hours after use of the drug is observed increase in endogenous Interferon compared to the normal background in 2-2, 5 times. Such an amount of a protein having immune properties stored for the next 6-8 hours. The increased number of natural killer It observed for 7 days after a single application of the pharmaceutical preparation.
Indications
- chronic papilloma viral infection (may be associated with oncogenic types of human papilloma virus);
- warts Flat and plantar Warts ;
- influenza, acute respiratory viral diseases ;
- chronic recurrent herpes first and second types;
- prevention of the development of dysplasia and cervical cancer ;
- urogenital diseases That are infectious nature (including those of mixed character);
- sharp hepatitis B and FROM moderate (in the complex therapy of this disease).
Contraindications
- individual sensitivity, inherited or acquired intolerance integral components of a pharmaceutical preparation;
- expressed autoimmune diseases ;
- period pregnancy or breast-feeding ;
- pediatric medicament are used.
Side effects
Side effects of the treatment according to the pharmaceutical drug is relatively rare, since the composition of the drug is fully described active substances. In rare cases may occur:
- weakness;
- dizziness ;
- allergic reactions ;
- headache ;
- the emergence of new elements rash during therapy herpes infection .
Instructions on Allokin-Alpha (method and dosage)
How to breed injection?
The contents of the ampoule (lyophilized powder) should be dissolved in 1 ml isotonic sodium chloride solution . It not recommended to use any other solvent, even from the group of crystalloid. If conservative therapy consists of several pharmaceutical drugs to be administered subcutaneously, in syringe to mix the drug solution is strictly prohibited. Use ready-to-Alpha injection Allokin immediately, because over time lost the therapeutic effect of the drug and its administration is inappropriate.
Injections Allokin Alpha, instructions for use
A drug solution is introduced in the form of subcutaneous injection . As stabbing subcutaneously should learn from qualified medical personnel. Below is the general workflow:
- Treat your hands to the level of hygiene.
- Help the patient to take the correct position (depending on the injection site).
- Put on sterile gloves and treat hands with a cotton ball with 70 per cent alcohol.
- Centrifugal or from top to bottom to process the first cotton ball skin on a wide radius, the second ball to pass directly over the puncture site.
- The skin at the injection site to take a crease.
- To conduct injection angle of 45 degrees to the surface of the skin, the needle entering shallow - about 15 mm (2/3 of the entire length).
- Forefinger to fix the needle cannula.
- Slowly introduce the drug.
- Remove the needle, holding her by the cannula and cover the injection site with a cotton ball soaked with alcohol.
Where stabbing defines members of the medical personnel who manipulate. Generally, hypodermic injections are given in the upper third of the outer surface of the shoulder, the back chuck, the anterolateral thigh or the lateral surface of the abdomen.
Driving and dosage
Conservative treatment drug Allokin Alpha determines the physician as it is individual and depends on the severity of the disease and the patient's condition:
- pathologies caused by oncogenic types of human papillomavirus - 1 ml of drug every 48 hours through 6 injections;
- recurrent herpes infection - Shows the introduction of 1 mg alloferon every 48 hours over 3 injection;
- acute hepatitis B or FROM - 1 vial of the drug three times a week after a significant confirmation of the diagnosis by laboratory tests (total rate increased to 9 shots).
Overdose
Clinically confirmed cases of overdose described.
Cooperation
Care should be taken to a combination Allokin Alpha and preparations Group immunomodulators in the complex therapy. Recommended holding Regular diagnostic blood tests when the inevitability of the simultaneous application of these drugs.
Combination with Alpha-Allokin Acyclovir in the treatment of chronic recurrent forms Genital herpes It is permitted, as a result of a different mechanism of action of the active components of pharmaceuticals, their antiviral effects potentiate each other (general therapeutic efficiency is greatly improved).
Terms of sale
Released only on presentation of the receptor form, signed and stamped by the attending physician.
Storage conditions
Keep the vials with a solution for injection in a dry, dark place, away from children at the recommended temperature range of 2 to 8 degrees Celsius.
Shelf life
2 years (ready solution to store prohibited).
Cautions
At hepatitis B and FROM comprehensive treatment should be carried out no later than the seventh day from the start of the active symptoms jaundice :
- ikterichnost sclera and skin (characteristic staining);
- dark brown urine (described in medical references such as " strong tea "Or" dark beer ");
- stearrhea - Pale or unpainted chair with drops of fat;
- fever . chills ;
- pain in the right upper quadrant (upper abdomen).
During the course of conservative treatment should abandon self-driving or other potentially life-threatening mechanisms, as noted isolated cases of dizziness during the application of the pharmaceutical preparation.
Analogs Allokin Alpha
Match code ATC 4th level: The pharmaceutical preparation is virtually unique in its kind, as the indications for its use cover a wide range of viruses, and the side effects or adverse effects are observed only in isolated cases. Because analogues Allokin Alpha represented only alloferon .
Babies
Use of the drug strictly contraindicated in pediatric patients (can be used in the treatment only after 18 years).
Allokin Alpha and alcohol
Formally, spirits do not interact with the integral components of a pharmaceutical preparation, but it is recommended to completely eliminate alcohol from your diet during the course of medical treatment. This precaution is due to influences which Allokin Alpha has on the human body.
Under the action of the active substance increases the concentration of circulating Interferon And this plasma fraction quite sensitive to changes in blood chemistry. Because alcohol-containing beverages may cause unpredictable side effects.
During pregnancy and lactation
The pharmaceutical preparation should not be used during pregnancy and breast-feeding as the active component can have adverse effects on the developing child's body, however, mutagenic . teratogenic or foetotoxic effects medications in clinical trials was found.
If during lactation replace the therapeutic effect of antiviral agents is not possible, it is recommended to discuss the termination of breastfeeds from a qualified specialist.
Reviews Allokin Alpha
In the pharmaceutical preparation is a good reputation, based on the various forums or other Internet resources. People are treated according to the drug, the overwhelming majority are satisfied. Allokin-alpha exerts its therapeutic effect for a short time period and shows really good results, as the effective component is extremely active.
Reviews at Herpes once again confirmed the view of patients, especially if you use a complex therapy with alpha and Allokin Acyclovir Because their effects potentiate each other, which greatly increases the efficiency of conservative treatment. Unpleasant rashes tested on the second or third day after the start of the active drug rehabilitation, as opposed to mono therapy by any means (significant therapeutic result can sometimes wait up to two weeks).
Reviews of doctors Allokin Alpha also favorable. Of course, the medical staff of public institutions complains about the price of the drug, but in terms of the Pharmacy - Allokin Alpha really is unique in its kind. Performance indicators affect even people far from medicine: prevention of dysplasia and cervical cancer is successful in 98 percent of cases, and treatment of human papillomavirus - 96 percent.
Price Allokin Alpha where to buy
Price Allokin Alpha 6 vials in the Russian Federation significantly depending on where you purchased the pharmaceutical preparation. So Ekaterinburg offers cost 3200 rubles to buy Allokin Alpha in Moscow can be over 3,400 rubles, and in Krasnoyarsk the price of the drug varies from 3,500 rubles.
Price Allokin Alpha in Ukraine is more stable. In all regions of the country the average price of the drug is at the limit of 1000 hryvnia.
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