Angiovit

Description overdue on 06/27/2014

• Latin name: Angiovit
• ATC code: A11VA
• Active substance: Multivitamins (Multivitamins)
• Manufacturer: Altayvitaminy (Russia)

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Angiovita
• Contraindications
• Side effects
• Instructions for use Angiovita (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Synonyms
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition Angiovita

• Vitamin B6 (pyridoxine hydrochloride)   - 4 mg;
• Vitamin B9 (folic acid)   - 5 mg;
• Vitamin B12 (cyanocobalamin)   - 6 g;
• glucose as an optional ingredient.

Product form

White, dual-layer (seen in section) biconvex film-coated tablets in blister of 10 pieces. In a cardboard box - 6 contour blister (only 60 tablets in a box). Also, the tablet can be packed in plastic cans, of 60 pieces each, then in cardboard packaging.

Pharmacological action

Angiovit - a combined pharmaceutical formulation comprising B vitamins Whose action is directed primarily on the metabolism methionine (aliphatic, irreplaceable, sulfur-containing alpha-amino acid). Biological effects contribute to enzyme activation In tsistation-synthetase   and methylenetetrahydrofolate Carrying transsulfatsiyu and remethylation given amino acid. This allows greatly accelerate the metabolism of methionine to reduce the concentration of free Homocysteine   in blood plasma.

Thus vitamin complex prevents the development of these diseases ( hyperhomocysteinemia and elevated concentrations of methionine   Plasma is a key element in the pathogenesis of 60-70 percent of all cardiovascular diseases):

• atherosclerosis   great vessels;
• thrombosis   arterial bed;
• ischemic stroke   brain;
• myocardial infarction ;
• Diabetic angiopathy ;
• chronic (habitual) not vynashivaemosti pregnancy ;
• congenital abnormality of the fetus.

Recent research in the field of pharmacology homocysteine ​​demonstrate conjugation of higher concentrations of the amino acids in the blood plasma uneasy with such diseases as senile Dementia   or Elderly dementia . depressive states . Alzheimer .

Pharmacodynamics and pharmacokinetics

Vitamin complex is rapidly absorbed after oral administration.

Indications Angiovita

Long-term prevention and treatment of diseases of the cardiovascular system:

• coronary artery disease ;
• angina   ІI-III functional class;
• myocardial infarction ;
• ischemic stroke ;
• sclerotic cerebral blood flow;
• Diabetic vascular lesion.

We should also point out that the drug is used for normalization of the fetoplacental circulation   (mass exchange of blood between mother and fetus during the prenatal period of development).

Contraindications

Individual intolerance or hypersensitivity to the drug or integrated applications.

Side effects

Typically, vitamins are well tolerated by the body, especially in the spring and summer and autumn, when celebrated their failure. However, in some cases, there may be clinical allergic reactions overall or localized nature ( angioedema . hives .   itching   and so forth) or other undesirable effects ( headache . dizziness , Increased sensitivity of the skin, symptoms of physiological sleep disorders cycles). Also disclosed dyspeptic symptoms   as nausea, vomiting, epigastric pain , Or burping flatulence after an intensive course vitamin.

Instructions for use Angiovita (method and dosage)

Vitamin complex is used orally . Tablets can be taken both before and after meals, abundantly with water. You should be careful with the shell, it can not be damaged by using a drug that is not necessary to chew or crush the tablets, because this way we can reduce the pharmacological effect Angiovita to nothing. The duration of the conservative course   treatment is determined by the attending physician, usually it is from 20 to 30 days, depending on the individual indications, and status of the patient.

Instructions on Angiovit also states that it is necessary to take one tablet a day, preferably in the morning, in order to protect the body for the whole day. Clinicians say that treatment can be started with two capsules at excessively high levels of homocysteine ​​and methionine.

Overdose

Cases of overdose have not been found, however, in case of an uncontrolled use of vitamin complex and balanced diet may have symptoms of hypervitaminosis:

• fine motor incoordination of the upper extremities, partial numbness of body parts   when an excess vitamin B6 ;
• not passing, long convulsions , Especially in the calf muscles (the effects of increased concentration Vitamin AT 9 );
• thrombosis of small vessels and even anaphylactic shock   at hypervitaminosis B12 .

Cooperation

Folic acid (vitamin B9) Which is part of the complex preparation Angiovit greatly reduces the effectiveness of Phenytoin (antiepileptic and antiarrhythmic agent), which requires increasing its daily dose. Accurate readings are encouraged to ask a qualified pharmacist or doctor.

Antacids aluminum and magnesium   (antiulcer pharmacological group) Kolestiramin, sulfonamino   reduce the effective absorption of vitamin complex (pharmacokinetic incompatibility), which manifests itself in the weakening of the useful effect of the drug.

On the metabolic conversion stage Vitamin B9   its pharmacological effects reduce drugs which inhibit dihydrofolate reductase. For example, should not be taken in combination with Angiovit Methotrexate . Triamterene or pyrimethamine .

Hydrochloride pyridoxine (B6)   greatly enhances the effect of thiazide diuretics   (reduced the already small proportion of urine, increased urination, especially during the day), but it weakens Activity Levodopa (antiparkinsonian agents acting on adrenergic and dopaminergic receptors of the central nervous system).

Weaken the effect of vitamin B6 the following drugs:

• hydrazide isonicotinyl ;
• penicillamine ;
• cycloserine ;
• estrogensoderzhaschie Contraceptives .

Separately, it should be emphasized that pyridoxine promotes increased production of contractile proteins of the myocardium, which is manifested in increased resistance to hypoxia of the heart muscle if prescribe vitamin complex, together with Angiovit cardiac glycosides .

Aminoglycoside antibiotics , Antiepileptics, salicylates . Colchicine   and potassium supplements   reduce gastric absorption Cyanocobalamine .

Comprehensive welcome Thiamine   and Cyanocobalamine increases the risk of allergic reactions and adverse events (see. The side effects).

In no event should not be combined with vitamin complex Angiovit drugs that affect coagulation. This can lead to an increase in its viscosity, stagnation and thrombosis even small arteries.

Terms of sale

The pharmacy dispensed without a receptor form.

Storage conditions

Angiovit should be stored in a dry place away from children, to save from direct sunlight at a constant temperature (15 to 25 degrees Celsius).

Shelf life

3 years.

Synonyms

Medivitan.

Angiovit during pregnancy

Reviews on Angiovit during pregnancy suggest that comprehensive prevention conservative to avoid disastrous hypovitaminosis B vitamins And therefore prevents the development of severe fetal abnormalities, such as:

• heart disease ;
• physical underdevelopment of the vascular system;
• the weakness of the immune system ;
• lag in mental and physical development.

It should also be noted that it is recommended to use at Angiovit planning pregnancy As a pharmaceutical drug has a positive effect on the development of the central and peripheral the nervous system of the child It contributes to the correct tab germ layers and their physiological development during fetal ontogeny.

Reviews Angiovite

Reviews on various pharmaceutical forums indicate productivity vitamin complex. The cardiovascular system is gradually stabilizing, and few side effects, usually cropped medication. Angiovit increasingly include concomitant system of prevention and treatment of coronary artery disease, because the regulatory action of biologically active substances improves the quality and duration of life, especially in people predisposed to Diseases of the cardiovascular system .

Reviews on Angiovit when planning pregnancy also confirm the positive effect of vitamin therapy. The mother's body is strengthened by such conservative treatment and is increasingly becoming ready for future delivery. However, the drug should be taken under strict medical supervision, in order to properly qualified to correct internal balance of ions and metabolism of basic substances.

Price Angiovita

Price Angiovita in Russia ranges from 200 to 240 rubles per pack.

In Ukraine, the price of vitamin complex is about 200 hryvnia per tablet in the polymer bank.

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