Xeomin

Description overdue on 11/30/2014

• Latin name: Xeomin
• ATC code: M03AX01
• Active substance: Botulinum toxin type A (Botulinum toxin type A)
• Manufacturer: Merz Pharma GmbH & Co. KGaA (Germany)

Photos of the drug

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Xeomin (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Reviews
• Price, where to buy

Composition

The medicine includes botulinum toxin type A . human serum albumin . sucrose .

Product form

The drug is available in vials in the form lyophilisate   white.

Pharmacological action

Miorelaksiruyuschee   means.

Pharmacodynamics and pharmacokinetics

The action of the tool, as well as other botulotoxins , Based on the blocking of nerve impulses, which are addressed to a specific group of facial muscles. Wrinkles disappear, because the muscular tissues cease to decline. As a result, relax injected   muscle. Maximum efficiency is achieved in the forehead, neck, nasolabial folds, and around the eyes.

The medicament begins to act for about 4-7 days after injection. The effect of each treatment usually lasts 3-4 months, although it may be less.

Indications

The drug is taken at:

• blepharospasm ;
• immobility arm muscles after suffering stroke ;
• idiopathic cervical dystonia ;
• facial wrinkles.

Contraindications

This tool is contraindicated in:

• violations neuromuscular transmission ;
• adverse reactions to the components of the drug;
• elevated temperature;
• pregnancy ;
• childhood;
• breast-feeding ;
• various acute diseases.

Side effects

The drug usually does not cause adverse reactions. It has no complexing proteins, often provoking allergy .

In therapy Blepharospasm   you may receive ptosis . paresthesia . conjunctivitis , Dry mouth, rash, headache . muscular weakness and dry eyes . Furthermore, there may be diffuse skin rashes   or dermatitis , Watery eyes, keratitis . lagophthalmos , Irritation, photophobia, fatigue, diplopia , Focal facial paralysis, blurred vision, ectropion . dizziness , Weakness of facial muscles, volvulus century visual disturbances. In rare cases, the possible local swelling of the skin of the century, keratohelcosis . Acute angle-closure glaucoma .

In therapy spasmodic torticollis may occur asthenia . dysphagia , Back pain, muscle weakness, tightness, or inflammation at the injection site, tremor , headache, colitis , Increased sweating, diarrhea , Hoarseness, pain in the bones, vomiting, skin rash, dry mouth, skin peeling, myalgia , Pain in the eyes, itch . In addition, the possibility of infection of the upper respiratory tract, dizziness, numbness, catarrhal symptoms, irritation at the injection site, increased blood pressure, rhinitis , Weakness, muscle weakness, breathlessness , Malaise, nausea, fever , Speech disorder, diplopia . ptosis .

In addition, the known information about some of the common side effects. For example, such as arrhythmia   and myocardial infarction .

Instructions for use Xeomin (method and dosage)

Instructions on Xeomin are advised to apply a special anesthetic cream. The effect of getting rid of wrinkles is noticeable on the second or third day, the final result will be after 10-14 days. Repeated administration may be performed once in a maximum of 4 months. The exact dosage and administration of the place determined by the expert.

With blepharospasm recommended initial dosage administered at 0, 05-0, 1 mL each injection site. The total dosage is not more than 100 units for the 12 weeks of therapy. Injections   to do medial   and lateral circular muscle of the eye. If vision is impaired due to the emergence of spasms You can make additional injections. The effect is noticeable, usually within 4 days after the administration. It usually lasts for 3-4 months.

If the effect of the drug lasts for less than two months, after repeated dosing procedure can be increased by 2 times. But the initial volume should not exceed 25 units in 1 eye. For each injection site a maximum dosage - 5 units.

For treatment spasmodic torticollis   the dose is adjusted individually. The maximum dose during a single procedure should not be more than 200 units, but the appointment of a physician can enter up to 300 units. The maximum dose at the same injection site - 50 units.

Injections are made in sternocleidomastoid muscle ; at scalene muscles ; at trapezius muscle ; at belt muscle ; in the levator scapulae muscle. But you should not chop both   sternocleidomastoid muscle   one procedure, since it increases the likelihood of side effects. The right amount injection   It depends on the magnitude of the muscle.

For administration in the superficial muscles of the needle used with the numbers 25, 27 and 30 for G. injection   deep muscles - needles number 22 G.

To determine the muscles involved may need rheotachygraphy . The effect of the drug is usually noticeable within a week after application and lasts totaling 3-4 months. The interval between each treatment should be at least 10 weeks.

Reveals the bottle, removing the stopper, at a dilution of medication is prohibited. Removed the plastic cover and the central part of the cork is treated with alcohol prior to use. Then sterilized needle pierced it. Injected into the vial isotonic sodium chloride solution 0, 9% . The mixture was gently stirred by turning the bottle to complete dissolution lyophilized powder . The solution eventually must give a clear, free of particles and flakes. At 10 U / 0, 1 ml of the powder have 1 ml of solvent.

It is advisable to apply the solution immediately after preparation. If necessary, it can be stored in a refrigerator for about a day when dissolution was carried out under sterile conditions.

Overdose

This tool is in high doses can cause pronounced muscle paralysis   even in places that are distant from those where the injections.

The patient should be hospitalized. Hold general supportive measures. If respiratory muscles are paralyzed, necessary intubation   and IVL Until the condition becomes normal.

Cooperation

It is undesirable to use the drug in conjunction with aminoglycosides   and spectinomycin . Precautions do injection   against application muscle relaxants   peripheral actions. The action of the drug can be affected by the derivatives 4-aminoquinoline .

Terms of sale

The medicine can only buy special institutions, which conducted the relevant medical and cosmetic procedures.

Storage conditions

Keep the medication you need in reach of children. Temperatures up to 25 ° C.

Shelf life

Three years.

Analogs

For a long time in cosmetology among the drugs for skin rejuvenation was in the lead Botox . This is one of the most popular analog Xeomin. Moreover, in our time can be used, and it is worthy competitors such as Dysport   and Lantoksom . What is it and what means of effective, often customers are interested in beauty centers.

Which is better - Xeomin or Botox?

In our time, the question of which is better, or Xeomin Botox It is quite relevant. Many do not know the difference between these drugs, have no idea about their positive and negative qualities.

Both tools are neurotoxins, but they are produced in different countries: Botox   - In Germany, and Xeomin - in Ireland. Here are some of its advantages compared with Botox :

• It does not need necessarily stored in the cold.
• Not addictive.
• Need a small dose.
• Side effects are rare, while from Botox   it's often a rash.
• The negative effect of virtually invisible, so that after the procedure, there are no problems with facial expressions.

In addition, it has its own advantages and Botox :

• Suitable for the treatment of hyperhidrosis.
• More media studies.
• Long-lasting effect, which lasts about six months.

Thus, each of these tools has its own positive and negative points. Choose for yourself one or the other drug should be given their all. In addition, it can help customer reviews beauty centers.

Dysport or Xeomin - is better?

Among the drugs that are used for anti-aging treatments, known and Dysport . It is also made on the basis botulinum toxin type A . The two drugs have their similarities and differences, so it is often possible to meet the question, or Xeomin Dysport - what's better?

The undoubted advantage of the first means is that it does not contain complexing proteins. AT Dysport they are necessary to preserve the integrity of the formulation, but they slow down the stimulation of antibodies . Moreover, the absence of complexing proteins reduces the chance of allergic reactions.

However, Xeomin is less effective for people with excessive sweating, as he reduced diffusion properties. So some patients more suitable Dysport .

Which is better - Botox, Dysport, or Xeomin?

The three popular drug for getting rid of wrinkles developed on the basis of botulinum toxin type A . However, each has its own nuances. Botox   It is more popular in the United States. And in Europe, the British increasingly used tool Dysport Because it is much cheaper, but it is not inferior to the properties and indications.

Ultimately, the single answer to the question: "Which is better - Botox, Dysport or Xeomin ? " - does not exist. All three drugs are used mainly for the same aesthetic injection Nevertheless, they can not be interchanged. After all, each of them created from their specific strain So that it has its own characteristics, as in the safety profile and in efficiency. What would be an effective tool in a particular case, one chooses for himself.

Reviews of Xeomin

Negative feedback on the forums Xeomin rare. Customers beauty centers, usually either not heard of it at all or find much more profitable than Botox . Nevertheless, there are those who still doubt this facility. They say that Botox   more familiar and studied, so it is best to use it. Moreover, the effect in its application lasts longer.

Positive reviews of Xeomin reported that it is quite effective. Especially note that the negative actions after his application no. A person becomes like a mask, what happens after Botox .

Here are a couple of photos before and after the use of Xeomin, which can be found in a review.

Price Xeomin where to buy

Buy this tool can only specialized institution. Price per unit of Xeomin is considered to be quite high. 100 units of the drug in the same package cost about 10,500 rubles. 50 units in one package can be bought on average for 6100 rubles.

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