- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use hexicon
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
In part one suppository Hexicon It includes 16 mg Chlorhexidini bigluconas And polyethylene oxide basis (polyethylene 1500 / Polyaethylenoxydum 1500 400 PEO / Polyaethylenoxydum 400).
Part A candle Hexicon includes 8 mg Chlorhexidini bigluconas And polyethylene oxide basis (polyethylene 1500 / Polyaethylenoxydum 1500 400 PEO / Polyaethylenoxydum 400).
AT solution for external use contained 0, 5 mg sodium Chlorhexidini bigluconas with a concentration of 20%, purified water (Aqua purificata).
One hundred grams gel contained 0, 5 g Chlorhexidini bigluconas and auxiliary components: Cremophor - RH 40 (Cremophor RH 40), poloxamer 407 (Poloxamerum 407), purified water (Aqua purificata).
One vaginal tablet Hexicon It contains 16 mg Chlorhexidini bigluconas (as a solution Chlorhexidini bigluconas a concentration of 20%) and auxiliary components: microcrystalline cellulose (Cellulosum microcrystallisatum), corn starch (Amylum maidis) pregelatinized, povidone (Povidone), low molecular weight, stearic acid (Acidum stearicum), lactose monohydrate (Lactose monohydrate).
Product form
Manufacturer releases the drug in the form of:
- pessaries 8 and 16 mg;
- solution;
- gel;
- vaginal tablets 16 mg.
Pharmacological action
Hexicon belongs to the pharmacotherapeutic group of drugs antiseptic and disinfectant action . When interacting with structures microbial cells He violates livelihoods, inhibits the development and provokes death pathogenic microflora .
The use in gynecological practice various dosage forms hexicon not only successfully fight pathogens But also to carry out prevention PP infektsionnnyh transmitted diseases.
Pharmacodynamics and pharmacokinetics
Included in the hexicon as an active ingredient chlorhexidine a strong disinfecting agent, which exhibits a sensitivity to a wide range of Microorganisms Including including Gram (+) and Gram (-) bacteria . protozoa . herpesvirus .
Hexicon effective against:
- gonokokkov (Neisseria gonorrhoeae);
- Treponema pallidum (Treponema pallidum);
- Chlamydia (Chlamidia spp.);
- gardnerellas (Gardnerella vaginalis);
- ureaplasmas (Ureaplasma spp.);
- Bacteroides fragilis (Bacteroides fragilis);
- Trichomonas (Trichomonas vaginalis);
- herpes virus type II (HSV-2).
The low sensitivity to the drug characterized individual strains Pseudomonas (Psevdomonas spp.) And Proteus (Proteus spp.). Resistance to its effects are viruses . mushrooms . bacterial spores . acid-resistant bacteria .
Due to included hexicon chlorhexidine formulation has several advantages over other antimicrobial and antiseptic . He:
- It does not violate the natural microflora of the female genital tract and it has no effect on the activity lactobacilli ;
- not addictive and resistance to its action in sensitive to it Microorganisms (even with repeated application);
- approved for use in the treatment of pregnant and lactating women ;
- saves (although to a lesser extent) the activity in the presence of bleeding and pus.
Efficiency is also provided suppositories features within them polyethylene 1500 (Polyaethylenoxydum 1500) and polyethylene oxide 400 (Polyaethylenoxydum 400). These agents provide a more uniform distribution of the active substance on the surface mucosa and its deeper penetration into the fabric.
In addition, the foundation polietilenkosidnaya dehydrate pathogens and clears mucous from accumulating on it their metabolic products.
Vaginal tablets Hexicon been developed as alternatives suppositories. For some women, they are more convenient than the spark, as void volume does not increase, and hence does not require the use of additional hygiene products.
Almost not absorbed from the GI And through the skin and mucous membranes when applied topically. Systemic absorption when applied vaginally tablets Hexicon extremely small.
If swallowed inadvertently 0, 3 g Cmax achieved after half an hour and is 0, 206 mg / l.
Drug is eliminated from the body mainly with intestinal content (90%) excreted by the kidneys than 1%.
Indications
Candles Hexicon - from what they are?
Candles Hexicon indicated for prophylaxis sexually transmitted infections Induced activity is sensitive to the action of the drug microflora For the treatment of inflammation of the genital organs in women for the prevention of inflammation and infection of the genital tract before birth, gynecological surgery, the procedure of abortion, intrauterine studies, etc ..
Indications for use of candles are Hexicon D Children gynecological diseases .
Indications solution, gel and vaginal tablet is the same as a suppository.
Additional indications for use of the solution
The solution is used as a disinfectant for treating purulent wounds and infected burns . In gynecology, urology and surgery are used to treat it infectious skin lesions and mucous .
Dentists prescribe rinse under hexicon thrush . gingivitis . inflammatory lesions of periodontal tissues and terminal respiratory tract .
Additional indications for use of the gel
The gel used Hexicon for the treatment of inflammatory diseases in gynecology . Dentistry and Urology . In addition, they treated the affected areas of the skin infection.
Contraindications
Contraindications to the appointment are hexicon hypersensitivity to its components.
Additional contraindications for a solution - Dermatitis .
Gel with caution and suppositories are used to treat children. The optimal dosage form for the child are suppositories Hexicon D.
Side effects
The most frequent side effects of candles - it allergic reactions . itch and burning in the vagina. These symptoms do not require specific treatment and tested independently after cessation of treatment.
Vaginal suppositories Hexicon D provoke undesirable side effects is less than 0, 1% of cases.
Adverse reactions to the use of the solution and are extremely rare. As a rule, they are expressed in the form allergy symptoms and itching Passing after the cessation of treatment.
Some solution Hexicon causes dry skin of hands, the stickiness of hands (usually no more than three to five minutes) dermatitis . photosensitization . Rinse the mouth they lead to tooth enamel coloring, tartar, taste disturbances. Similar phenomena can provoke and gel.
Instructions for use hexicon
Candles Hexicon: instructions for use
Candles are designed for intravaginal application.
For therapeutic purposes, twice a day for 7-10 days administered vaginally one suppository. If necessary, repeat the treatment after 20 days.
To prevent sexually transmitted diseases it is recommended to enter one suppository no later than two hours after unprotected intercourse.
Etc. Application Instructions Hexicon D is similar to the instructions for use of candles 16 mg.
Gel Hexicon: instructions for use
To treatment of inflammatory urological and gynecological diseases Gel should be applied to the affected surfaces twice a day. Duration of treatment may range from 7 to 10 days.
Infectious dermatological diseases treated finely causing gel on the affected surface, two or three times a day. How long will the treatment depends on the clinical situation.
In dental practice, an ointment applied in the form of applications to the multiplicity of 2-3 times a day. The duration of one treatment - from one to three minutes. Duration of the course is determined by the clinical situation.
Instructions for use of the solution
The solution is used topically and locally in the form of applications, irrigation and rinsing. To carry out the procedure one should be applied to the affected surface of the skin or mucous from five to ten milliliters with exposure means by one to three minutes, two or three times a day (the solution may be applied to the tampon or by irrigation).
To prevention Infections Who passed PP Hexicon appropriate to apply if the procedure would be held no later than two hours after sexual intercourse.
By means of the nozzle the liquid contained in the vial is introduced into urethra (both women and men) or in the vagina . The dose for administration into the urethra of men - from 2 to 3 ml for women - one or two ml. To vagina administered from 5 to 10 ml. The nozzle is delayed by 2-3 minutes.
Also, a solution should be treated with the sexual organs and the skin inner thighs and pubic area. It is not recommended to urinate within two hours after the procedure.
With inflammation of the urethra (including complicated prostatitis ) Is supposed to complex therapy that complements injection for ten days, once or twice a day into the urethra of the solution in an amount equal to 2-3 ml (recommended procedure every other day).
With diseases of the oral cavity designate rinsing solution preparation. The multiplicity of procedures - 3-4 per day. The amount of solution needed for a treatment - from 5 to 10 ml.
Instructions for use vaginal tablets
Before use, the tablet is moistened in water and is introduced into vagina .Sutochnaya Dose depending on the diagnosis is 1 or 2 tablets. The treatment is carried out for 7-10 days.
To infection prevention Which are transferred PP tablet as suppositories, it is recommended to introduce within two hours of unprotected intercourse.
Overdose
Because the drug is practically not absorbed from GI and not absorbed topically through skin and mucous The probability of an overdose it is considered unlikely.
To date, information about overdose hexicon not.
Cooperation
The efficacy increases with simultaneous use ethanol .
Do not use Hexicon with applicable intravaginal drugs, which include iodine.
Remediation external genitalia It has no influence on the efficacy and tolerability of candles, since they are applied intravaginally.
Pharmaceutically not compatible with anionic detergent (saponins, Sodium lauryl sulfate, Sodium carboxy methyl cellulose) and soap. Chlorhexidine inactivated in the presence of soap, so before using the product should be thoroughly rinsed from the skin and mucous soap residue.
Hexicon permitted to combine with drugs containing cationic group.
Terms of sale
OTC
Storage conditions
In a dry place at a temperature not higher than 25 ° C for tablets, liquid, suppository and not higher than 20 ° C to gel.
Shelf life
24 months
Cautions
Hygienic procedures do not affect the efficacy and tolerability of vaginal tablets and suppositories, as the drug in these dosage forms are administered intravaginally.
When applying the solution in patients with head injuries and spinal cord As well as in patients with perforation of the eardrum Should avoid it falling into the wound.
If the solution is accidentally falls on mucous membranes of the eyes , They are recommended to quickly and rinse well with water.
Contact with bleaching agents containing sodium hypochlorite its composition, at clothes previously been in contact with drug chlorhexidine It provokes the formation of brown spots on them.
Increasing the temperature of the solution is strengthening its bactericidal action . However, at temperatures exceeding 100 ° C, partial decomposition of the drug.
How to enter the candles?
To prevent leakage of the contents after the introduction of a suppository, a woman should lie on the bed, spreading the bent leg at the knee joints. The spark is introduced as deeply as possible into vagina the index finger (if possible at a depth of a finger).
If you enter a suppository is not deep enough, it may fall after a woman gets up, failing to dissolve.
The principle of operation is similar to the principle hexicon vaginal baths. A feature of these candles is that lead them several times a day, thereby greatly increasing the number of discharges. Given this, the period of treatment should be as often as possible to change daily linings.
Another feature of suppositories is that prior to their introduction is not necessary to assign the additional sanitation vagina or douche, which makes them more convenient to use them as compared to other vaginal suppositories.
An important recommendation of the period of treatment is to eliminate sex. If the therapy on the background of a regular sexual life, the positive result is achieved. There remains the risk of re-infection, and as a result - you may need to prescribing not only local, but also systemic effects.
Application hexicon during menstruation
Quite often there are questions whether you can use candles during menstruation and whether menstruation treated with vaginal tablets.
The instructions to hexicon indicated that the use of suppositories and tablets during menstruation is permissible. This is due to the fact that the active ingredient of the drug is maintained (although to a slightly lesser extent) the pharmacological properties in the presence of pus, bleeding, and other biological fluids.
Analogs hexicon
Match code ATC 4th level: Analogs of the composition for hexicon in the form of a solution and a gel - a drug Amident (Solution for topical application), and Chlorhexidine in the form of an alcohol solution, a solution, a concentrate for preparation of a solution spray.
On the mechanism of action of the closest Bepanten (cream) Depantol (cream) Lavasept (concentration for solution) Tsiteal (solution).
Candles and tablets Hexicon have a similar structure with, respectively, candles and tablets Chlorhexidine . Similar preparations of the mechanism of action for suppositories - is Betadine (Suppositories) Gipozol (aerosol) Yodovidon (candles) Yodoksid (candles) Makmiror (cream, capsules, tablets, suppositories) trihomonatsidom vaginal suppositories, vaginal suppositories evkaliminom, Trihomonatsid (pills), Furazolidone (powder, tablets, granules for suspension) Vagiflor (capsules) Povidone iodine (Suppositories) Dafnedzhin (cream) Laktozhinal (capsules).
Hexicon during pregnancy
All formulations sold under the brand Hexicon except vaginal tablets are allowed to appoint at pregnancy and between breast-feeding . The instructions on the candle at Hexicon pregnancy and Lactation It states that this agent is considered to be not only effective, but also safe for both mother and child.
As for the vaginal tablets, their application is possible if the benefit to the mother outweighs the risk to the fetus.
Candles at Hexicon pregnancy It is one of the most commonly prescribed drugs for the treatment and prevention gynecological diseases . Security is provided by the preparation of its local impact and confirmed by long experience of application.
By acting locally, its active substance hardly enters systemic circulation and thus do not pose a threat to the normal development of the child. Therefore, the spark may be used at all stages of pregnancy.
Hexicon effective at pathogens Which are the cause of women's diseases, but it does not cause any violations of its own vaginal flora .
In the 1st and in the 2nd trimester of this allows you to assign a preventive measure Infectious Diseases Transmitted PP ( Syphilis . ureaplasmosis . trichomoniasis . gonorrhea . Chlamydia . Genital herpes ), And for treatment of vaginitis . colpitis . bacterial vaginosis . endo- and ekzotservitsitov .
The trimester 3 (and in particular, prior to delivery) Hexicon indicated for the prevention of infectious and inflammatory processes during and immediately after childbirth.
Use candles and cervical erosion . They should be administered in cases where the cause of ulceration is an active pathogens transmitted PP, inflammatory or "female" disease.
During pregnancy Hexicon often prescribed for bacterial vaginosis When in vagina prevail pathogenic bacteria And the amount of lactic acid bacteria (lactobacilli) - reduced or non-existent these bacteria.
Reduction of lactic acid bacteria a pregnant woman in the background bacterial vaginosis can cause the development of vulvovaginal candidiasis (or, in other words, thrush ).
Experience shows that every year, a combination candidiasis and bacterial vaginosis It becomes more and more. For this reason, it is widely believed the effectiveness of candles at Hexicon thrush .
Candles Hexicon from yeast
Provokes vulvovaginal candidiasis yeast-fungus genus Candida Who, like many viruses . bacterial spores and acid-resistant strains of bacteria Are immune to the effects of chlorhexidine .
So why do these candles at the appointed pregnancy thrush ? The fact is that the cause thrush It is the uncontrolled growth of Candida fungus colonies Which can be triggered including the activity of infectious agents - gonokokkov . Trichomonas and other bacteria and protozoa .
In such cases, when the infection It is mixed, fungal-bacterial in nature , The feasibility of hexicon due to its ability to effectively remove the signs of inflammation, reduce
. or ).
pregnancy thrush
allergy .
pregnancy
Get the best price and buy
Furiousness It is a viral infection of zoonotic nature. Man infection is transmitted through the saliva of carnivores due to bites. The infection is accompanied neuronal degeneration in the brain and spinal cord. Rabies in humans is manifested symptoms of a deep disorder of the nervous system, as evidenced by high arousal . manifestation aggressiveness . Dementia Which eventually causes paralysis and subsequent death. 
While incubation period It depends on whether, in what Mete took a bite or licks. So if the infection got into the body through the area on the face or head, the incubation period lasts two to four weeks. If the damage occurred in the legs, then this period can last from several months to one year. The disease can be divided into three distinct periods: the initial period (depression), as well as periods of excitation and paralysis. 
To effectively deal with the manifestation of rabies in humans is necessary scheduled fight the spread of rabies among animals. This occurs through the use of mass routine vaccination, the destruction of diseased animals, following the rules of keeping animals at home, control measures for the transportation of animals within the country and across the border. In order to prevent by creating awareness among the people and those who are involved in working with animals, do preventive vaccination. Grafting involves three intramuscular administration of the vaccine in a dose of 5 ml into the deltoid muscle of the arm. If there were scratches or bites should immediately wash the wound thoroughly with soap water. The edges of the wound then treated with an alcohol or tincture of iodine , Imposed on the wound sterile dressing. Those who are injured as a result of an animal bite, immediately poison specialists for the course rabies vaccination . It is important to bear in mind that the effectiveness of vaccination is expressed only when it made not later than the fourteenth day since the animal bite. 
Tsiteal 
Depantol 
Bepanten Plus 
Chlorhexidine digluconate 
Dysphagia - A condition in which a person feels when passing food through the esophagus gets stuck. It is sometimes marked tenderness. When dysphagia should be treated first and foremost to the otolaryngologist may also need to consult other specialists - a gastroenterologist, neurologist, psychotherapist. 
Pain when swallowing food, and is often accompanied by other features. Due to the fact that pain is manifested in the throat when swallowing, coughing person can, so that the food is in the nasopharynx. Sometimes the food can go back and poured through the nose. Severe pain when swallowing often accompanies heartburn , The sense voltage constant salivation. At a time when the food passes through the esophagus, a person may feel that there is pain when swallowing his Adam's apple. Sometimes this involves a feeling of suffocation, and in some species of dysphagia swallowing felt chest pain. In the area of the sternum discomfort appears: This person seems like a lump of food stopped in the esophagus and could not advance further. Later, the pain is felt in the esophagus when swallowing food. If the pain in the throat when swallowing is felt for more than one week should see a doctor to watch the beginning of a serious illness. 
Occurrence high esophageal dysphagia often associated with spasms of the esophagus mouth, protrusion of the esophageal wall. Also, this type of dysphagia develops in chronic and acute inflammation of the larynx and pharynx, in contact with foreign bodies. 
To correct this condition, the doctor initially conducting a comprehensive study. Practiced as a detailed survey and instrumental investigations. Can carried out X-ray of the esophagus, neck and chest, laringospkopicheskoe research. If there is suspicion of tumor development, biopsy. If you want to practice and other studies. 
Taufon 
Oftagel 
Retinalamin 
Korneregel 
Vizomitin 
Kvinaks 
Vidisik 
Thiotriazoline 
About thirty years ago, it was first identified immunodeficiency virus, after which the scientists also diagnosed with one of the most feared diseases of our virus - AIDS. "The plague of the 20th century" - was the name given to the virus is spreading rapidly across the globe. Until now, there is no single drug, guaranteeing a full recovery. Despite development of new vaccines against AIDS Unfortunately, in the 21st century, mankind has been forced to admit: AIDS - is incurable . 
Of all the Russian regions in the number of new cases AIDS infection leading Kemerovo region, where 100 thousand people is 144, 9 new carriers of the virus. It is followed by Samara region with the index - 117, 6. In the Irkutsk region, the figure is 110, 8, slightly inferior to the Sverdlovsk region - 109, 6, in the Leningrad region - 107, in Novosibirsk - 106, 3, in the Orenburg region - 96, 1 new HIV carriers. 
Statistic AIDS victims It suggests that infection by no one is immune. Buy HIV status can be anyone, regardless of religion, nationality, social status, etc. This idea is the basis of International Day of Remembrance of the Victims of AIDS . Every third Sunday of May, millions of inhabitants of our planet as a sign of sympathy and mourning for those whose lives took this terrible disease, and organize various activities in order to once again remind everyone of the danger posed by this deadly virus. 
Midriatsil 
Tropikamid 
Trombovazim 
Streptokinase 
Cosmetic treatment clean skin - one of the most painful procedures in cosmetology. Despite this fact, cleaning your face is perhaps the most popular procedure in any beauty salon. 
Making love the smell of perfume, long sitting in front of monitor ... The reasons for your headache may be set, as well as ways of dealing with it.