Description overdue on 08/24/2014
- Latin name: Potassium iodide
- ATC code: H03CA
- Active substance: Potassium iodide (Potassium iodide)
- Manufacturer: Obolensky pharmaceutical company (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacokinetics and pharmacodynamics
- Indications
- Contraindications
- Side effects
- Potassium iodide, instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Synonyms
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Formula potassium iodide - KI. The composition of one tablet Potassium iodide can include 100 or 200 mg of active substance. Eye drops - this solution, which contains 3% of active substance. In solution was Kaliya IODIDE may go in misc amount of active substance - 0, 25%, 10-20%.
Product form
Manufacturers produce tablets, drops, and a solution of potassium iodide. Tablets fit into amber glass jars. Potassium iodide solution of 3% is packaged in bottles of 200 ml. Eye drops sold in bottles of 10 ml.
Pharmacological action
Pharmacopoeia indicates that the drug has an effect on the function Thyroid , Influencing, in particular, on process of formation hormones . He suspends production thyroid stimulating hormone , Which is produced in the front lobe of the hypophysis, increases the activity of secretion of bronchial glands, contributing to separation of sputum. Potassium iodide also has proteolytic properties, that is, promotes the breakdown of proteins.
If the agent is applied topically, it has antiseptic activity obezzarazhivaya treated surfaces. Yet it is an important feature of this drug - prevention of the accumulation in the thyroid gland of radioactive iodine. The drug effectively protects the thyroid gland from the effects of radiation.
Pharmacokinetics and pharmacodynamics
If the environment contains a normal amount of iodine, it is exposed to excessive amounts of iodides suspended the biosynthesis of thyroid hormones, decreases sensitivity to thyroid stimulating hormone pituitary And block the production of thyroid stimulating hormone by the pituitary gland.
After potassium iodide is inside it completely and rapidly absorbed in the intestine. For two hours, he distributed within the cells of the body. Accumulation occurs to a greater extent in thyroid, iodide also accumulates in the mammary, salivary glands, in the gastric mucosa. The substance penetrates the placenta.
Excreted eliminated via the kidneys, with about 80% of the dose is within 48 hours, and the remaining part of the body is derived from 10 to 20 days. Also, a partial removal takes place with secrets, secrete saliva, bronchial, sweat glands and others.
Indications
The tool is used as a drug for the treatment of patients with iodine hyperthyroidism (thyroid disease), the development of endemic goiter (illness of the thyroid gland, which develops in connection with the the reduced maintenance of in water of iodine). Also, of his appoint in the process of of preparation for the operative interferences in people with pronounced form of thyrotoxicosis (illness, associated with the raised function of of the thyroid gland human). The drug is indicated for the prevention of radiation lesions of the thyroid gland. As an auxiliary drug used in the treatment Syphilis .
Potassium iodide, also appointed the following diseases:
- inflammatory disease of the respiratory tract;
- bronchial asthma .
Eye drops Potassium iodide appointed under the following conditions:
- eye disease (clouding of of the cornea, cataract , Hemorrhage);
- fungal diseases of the cornea and conjunctiva.
Contraindications
Do not assign this drug for the following diseases and conditions:
- tuberculosis ;
- nephritis, nephrosis;
- abrasions, acne;
- purulent inflammation of the skin;
- rash, bleeding diathesis;
- high sensitivity to iodine;
- pregnancy.
Side effects
In the treatment of potassium iodide can develop phenomenon yodizma. It is an inflammation of the mucous membranes of non-infectious nature, which is accompanied by a runny nose, hives , Swelling of the nasal mucosa, and other allergic reactions. If ingestion may experience an uncomfortable feeling in the pit of the stomach.
Furthermore, as a side reaction may occur tachycardia , Sleep problems, diarrhea , Sweating.
In the treatment with high doses of agents may develop hyperthyroidism. This occurs most often in older people diagnosed with nodular toxic goiter or diffuse type.
Potassium iodide, instructions for use (method and dosage)
Potassium iodide is taken orally in the form of solutions and tablets, in / in a contraindicated. Before the drug is recommended to drink it sweet tea, jelly or milk to prevent irritation of the gastrointestinal tract.
Patients, who are appointed by potassium iodide, instructions for use involves taking certain doses of funds for a particular disease.
If appointed Potassium iodide eye drops , Instruction involves the use of a 3% solution to be instilled into the conjunctival sac. Drop in each eye to be 2 drops, making it 3-4 times per day. The treatment period lasts from 10 to 15 days, depending on the disease.
People suffering from endemic goiter, appointed on the inside of 0, 04, 1 g of drugs once a week. If the patient suffers from diffuse goiter, it was originally shown at the reception 0, 04 grams of the drug three times a day, after which the dosage should be modified: at 0, 125 g of 1 or 2 times a day. Period of therapy continues 20 days, further should be ten-day break.
In order to liquefy sputum using 1-3% solution. It needs to take 2-3 tbsp. l. 3-4 times daily.
As an aid in syphilis assigned mainly such treatment is appropriate in the tertiary period. Under the influence of the drug reduced pain more intensely absorbed infiltrates. For the treatment of syphilis in 1 tbsp. l. 3-4% solution must be taken three times a day after eating.
For the treatment of of actinomycosis the lungs are appointed by the large doses of means of - 1 tbsp. Spoon 10-20% solution four times a day.
To protect from the effects of radioactive iodine adults and children after the age of two should get to 0, 125 g of 1 means every day. Children under two years shows a reception on 0, 04 g per day. Take the pill you need every day, until that time, until there is no threat of ingestion of radioactive iodine.
To provide protection from the effects of thyroid radofarmatsevticheskih preparations should take on 0, 125 g once daily for 5-10 days.
Overdose
With an overdose of any of the drugs Potassium iodide staining can be observed in the mucous brown. Also, in a patient it is happening vomiting, of his bothers pain in the abdomen, bouts of diarrhea. In severe cases, dehydration can occur, developing a state of shock.
In case of overdose should immediately wash out the stomach and enter the patient sodium thiosulfate . It is also practiced by symptomatic treatment, if necessary, the therapy is aimed at overcoming the state of shock, to restore the water and electrolyte balance.
In chronic overdose growing phenomenon yodizma accompanied by a metallic taste in the mouth, inflammation of the mucous membranes, acne, dermatitis, nervous excitability. In case of chronic overdose treatment should be abolished.
Cooperation
If carried out simultaneous treatment with high doses of iodine-containing drug and potassium-sparing diuretics, the patient may develop hyperkalemia.
With the simultaneous use of drugs lithium may develop hypothyroidism and goiter.
At simultaneous reception thiocyanate and perchlorate competitively inhibited the absorption of iodine by the thyroid gland.
In the treatment with antithyroid drugs noted mutual weakening effect.
Terms of sale
Released from pharmacies without a prescription.
Storage conditions
Eye drops, and the solution must be stored at a temperature not exceeding 25 ° C.
Shelf life
The drug should be stored no longer than 3 years.
Cautions
If the treatment is carried out in humans suffering renal failure May develop hyperkalemia. It is important to regularly check the level of potassium in the blood. If the treatment is carried out at home, you need to periodically visit your doctor.
Before treatment Potassium iodide is necessary to check the condition of the thyroid gland and to exclude the presence of malignant disease.
Synonyms
Potassium iodide.
Analogs
Potassium iodide analogues are other iodine-containing drugs: Jodomarin . Yodbalans . Iodine Vitrum et al. Which the drug should be used during treatment, the physician must determine.
Jodomarin or Potassium iodide: which is better?
Both drugs contain iodine and exert Relevant effects on the organism Rights and, respectively, such same indications to application. They differ only auxiliary substances. In addition, potassium iodide - a cheaper drug.
Babies
It is used under medical supervision. It is important to strictly adhere to the specified dosage.
During pregnancy and lactation
Potassium iodide during pregnancy may only be used at the recommended dosage. Iodine is able to cross the placenta, so it can cause an excessive amount of fetal goiter and hypothyroidism. When pregnancy before applying of this drug need to necessarily to consult a doctor.
Also, this element of allocated with thoracal milk. Therefore, if a nursing mother uses the drug to treat during feeding, and at the same dose exceeds 1 mg per day, in infants may develop hypothyroidism.
Responses to Potassium iodide
Leaving comments about the drug potassium iodide, people have commented that the facility has a reasonable price, the packaging of tablets lasts for an extended period. Potassium iodide is often used for prevention, but it is a review of the need to adhere to the dosage, which is prescribed by a doctor. As the side effects most commonly noted the appearance of acne. It is important to always check the state of the thyroid gland before treatment, so as not to aggravate the disease.
The price of potassium iodide, where to buy
Buy pills, solutions or drops at any pharmacy without a prescription. The price of potassium iodide is an average of 140 rubles for 100 pills. Price of eye drops - on the average 150 rubles.
No comments:
Post a Comment