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The preparation gipotiazid currently available in the form of standard tablet white flat shape. On one side of each tablet is present mark "H". As auxiliary components used magnesium stearate . talc . gelatin . lactose . starch . The tablets are packaged in blister pack of twenty.
Effect of the drug:
This drug from the group diuretics . Its action is to tackle the reabsorption of sodium ions, potassium, chlorine, magnesium, and the water of the distal nephron. After taking the drug after two hours diuretic effect is manifested most dramatic effect is observed after four hours, while it lasts for 6-12 hours. The drug hydrochlorothiazide has antihypertensive properties, which is why the drug is actively used by patients who have had hypertension. Wherein hydrochlorothiazide and administered as a drug for monotherapy, and as an integrated tool to enhance the antihypertensive effect of other drugs. The hypotensive effect of the drug is due to the stimulation of expansion of arterioles. But this thiazides effect on blood pressure.
Already on the coming few days after administration of the drug in patients with a decrease in blood pressure. However, to the therapeutic effect of the drug was due to the optimal, you must regularly take hydrochlorothiazide for three to four weeks. After taking the drug will be completely finished, hypotensive action It continues for over a week.
Indications:
Hypothiazid now actively used as a monotherapy, as well as an auxiliary medication in the treatment of hypertension. Also, the drug is well established in the treatment of edema syndrome that occurs as a result of various disorders in the body. It is also frequently used in the treatment diabetes insipidus As well as the prevention of stones in the urinary tract in patients belonging to the risk group.
Dosage:
Doses of this medication, as a rule, are set individually. When the diagnosis of "edema syndrome" is assigned to 25-75 mg / day of the drug. Typically, the drug hydrochlorothiazide administered through one or two days, although it is possible and the application of the drug every day. Patients nephrogenic diabetes prescribe the drug at 50-100 mg per day. This dose should be divided into 2-4 reception. Several days later, the dose can be reduced. Calculating the dose of the drug for children, keep in mind that 1 kg of body weight of the child to take 1-2 mg.
Possible side effects:
Before the drug hydrochlorothiazide possible manifestation hypokalemia , and hypochloremic alkalosis , Characteristic features of which is a dry mouth, a strong thirst Changes in heart rhythm, mood and mental instability, a feeling of weakness. It is also possible the development of hepatic coma or hepatic encephalopathy. People taking the drug also may experience arrhythmia, tachycardia, anemia, leukopenia.
As side effects in the digestive system is possible cholecystitis , Jaundice, pancreatitis, diarrhea, constipation . anorexia . Also, when taking the drug possible number allergic reactions .
Features of reception:
The drug should not be used for pregnant women and nursing mothers. Patients with severe renal and hepatic function the drug is prescribed with caution. If the drug is used for a long time, you must make general blood analysis for the control of a number of indicators.
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