Novocaine

Description overdue on 28.09.2011

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International name - procaine . Novocaine - analgesic drug, used for local anesthesia, with eczema , Spasms of blood vessels, the blockade. In some cases, the drug is used for dilution of antibiotics for the purpose of extending the period of action, for example, Penicillin . PM reduces the excitability of the cardiac muscle.

Dosage Form: powder, suppositories, solution in the ampoule, the solution in vials.

Indications:

Novocaine apply for analgesia during of operative interventions, for a cupping of phantom pains, when hypertension . When administered drug relieves pain caused by ulcerative lesions of the gastrointestinal tract. Suppositories are used for ulcerative colitis . anal fissures . hemorrhoids . In the form of ointments, Novocaine boltushek drug effective in neurodermatitis . dermatosis . eczema .

Contraindications:

The drug is contraindicated in hypotension . myasthenia , Hypersensitivity to procaine. It is unacceptable the introduction of drugs into the inflamed tissue. Never mix used with sulfonamides .

Special instructions:

Novocaine solution injected i / m in /. Rectal suppositories are administered 1 suppository at a depth of 4 cm to 4 times per day. The course of treatment is designed for 1 month. spoon 4 times a day for 30 minutes. before meals for two weeks. Also, the solution used for electrophoresis. When skin rash ointment is used externally: 5 and 10%. Apply to the affected skin 2 times a day. It is necessary to control the functions of the central nervous system, respiratory system, CCC. Novocaine reduces the concentration of attention, you need to give up driving vehicles. Acceptable use of the drug during pregnancy at therapeutic doses.

Side effect:

Central nervous system : Fatigue, weakness in the body, drowsiness, dizziness, migraine , Loss of consciousness, restlessness, lockjaw, nystagmus, seizures, tremor . paralysis   feet, vision, hearing hallucinations .   paresthesia , Respiratory paralysis.

Cardiovascular system : Unstable blood pressure, collapse, disruptions in the heart, peripheral vasodilatation, bradycardia, chest pain, arrhythmia.

The urinary system : Involuntary urination.

Hematopoietic system : Methemoglobinemia.

Overdose:

Dizziness, paleness, dyspepsia, shortness of breath, drop in blood pressure, apnea , Tachycardia, methemoglobinemia. CNS: hallucinations, motor excitation, convulsions. Treatment: pulmonary ventilation, inhalation of oxygen, detoxification. When seizures, overexcited - Barbamyl / m, or sibazon   w / w. Analeptics contraindicated. Spend transfusion therapy. When strongly expressed headaches take Amidopyrine .

Drug Interactions:

Local anesthetics increase the CNS depression. MAO inhibitors may lead to a sharp drop in blood pressure. Novocaine strengthens, lengthens the period of muscle relaxants. Procaine and narcotic analgesics   provide an additive effect to that used for epidural, spinal anesthesia (but inhibited respiration). Vasoconstrictors prolong the local anesthetic effect of the drug. Novocaine reduces the effectiveness antimiastenicheskih PM. Cyclophosphamide . antimiastenicheskie PM . demekarin . thiotepa . ekotiofat   reduce the rate of metabolic processes local anesthetics. PABA (metabolite of procaine) is an antagonist sulfa drugs .