Description overdue on 04/11/2014
- Latin name: Ipidacrine
- ATC code: N07AA
- Active substance: Ipidacrine
- Manufacturer: JSC Olainfarm, Latvia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications neuromidin
- Contraindications
- Side effects
- Instructions for use neuromidin (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One tablet contains: 0, 2 hydrochloride ipidacrine + Adjuvants ( starch, calcium stearate, lactose monohydrate ).
One ampoule contains the active substance ( hydrochloride ipidacrine ) 0, 05 or 0, 15 + auxiliary substances (water for injections).
Product form
- In tablets, the white circular form, packaging 10 pieces.
- The ampules - transparent and colorless liquid, 1 ml.
Pharmacological action
Drugs that act on the CNS anticholinesterase agents .
Pharmacodynamics and pharmacokinetics
Neiromidin a blocker calcium channel and reduces the amount of Potassium Accordingly increases the calcium concentration in nerve cells. Also, the drug prevents the effects of cholinesterase in nerve and muscle fibers. These two processes increase the number of mediators , such as serotonin, adrenaline, Oxytocin , Histamine cells. Activity postsynaptic cells is amplified, mediators can easily to pass through semipermeable membrane cells. The drug normalizes the process of transmission of nerve impulses for muscle tissue.
The man crush drug increases the tone smooth muscle , Restored synoptic regard, in the nerve fibers and facilitates the process of remembering.
After receiving the drug binds proteins in the blood and rapidly penetrates into target organs . The drug is metabolized in liver . Maximum concentration in the blood - 30 minutes. Excreted from the body via the excretory system - through the kidneys in urine and through the digestive tract.
Indications neuromidin
- polyneuropathy and mononeuropathy different degrees of severity;
- multiple sclerosis ;
- CNS disorders, paralysis ;
- violations of motor activity after injuries or organic lesions;
- indication for use in tablet formulation can serve lack of tone bowel .
Contraindications
You can not assign pills and injections neuromidin children under the age of 14 years.
Contraindicated in tablet form:
- patients with arrhythmia and bradycardia ;
- sick epilepsy ;
- at stomach ulcer ;
- at asthma and allergies some substances that are part of the drug;
- pregnant and lactating women.
Side effects
The drug increases salivation , may cause nausea and vomiting . skin rashes . bronchospasm and diarrhea .
Instructions for use neuromidin (method and dosage)
The drug is prescribed in tablets or parenterally in injections, depending on the disease and its severity. The maximum amount per day is 0, 2 g
According to the instructions on Neiromidin:
- at poly- and mononeuropathies medicine administered in / in or / m to 30 mg per day for 2 times of 10-15 days. Then 3 tablets per day (3 doses) for 30-60 days;
- at violations of motor activity after injuries or lesions organic parenterally administered intramuscularly 15 ml of the preparation two times a day, 15 days;
- Complex treatment multiple sclerosis - 1 tablet 4 times a day, 60 days, course repeat several times a year;
- atony bowel - 20 mg three times a day for 7-14 days;
- various CNS disorders - 5-15 mg two times a day for 10-15 days or 1 tablet 3 times / day for 3-6 months.
Overdose
In case of overdose there is loss of appetite, vomiting, nausea, diarrhea, bronchospasm , Heart disorder ( tachycardia, bradycardia ), The lowered BP , Anxiety, convulsions . jaundice , General weakness. Treatment is symptomatic, apply atropine or tsiklodol .
Cooperation
Enhances the effect of CNS depression in the application sedatives . Side effects increase ethanol and other anticholinesterase means. Reduces the effect of anesthetics . The drug can be used with nootropami .
Terms of sale
Prescription.
Storage conditions
In the dark, protected from children, cool, temperatures - above 25 degrees.
Shelf life
- Tablet form: 18 months.
- Injection: 12 months.
Analogs neuromidin
- Neostigmine methylsulfate
The same active ingredient (complete substitute drugs) contain aksamon, ipigriks amiridin and 20 mg.
Analogues of the drug are: kalimin 60 H proserine . Price for analogs lower than on the original source.
During pregnancy and lactation
The drug should not be taken during pregnancy due to the fact that it enhances the tone of the uterus. When lactation a medicine stands out with milk.
Reviews neuromidin
Reviews pill good. In the early days of the drug improves memory, the ability to think clearly and analyze consistently present information. They write that the drug greatly affects the heart, so you should take care of their well-being in the process of taking the medicine. Reviews injections positive, especially in patients with problems in the digestive tract.
Reviews on the admission children are practically absent. Many people do not rush to take the drug, due to age restrictions described in the instructions. Those who decided to receive such an important drug in the complex therapy in general are happy.
Price Neiromidin where to buy
Price Neiromidin tablets is about 600 rubles for 50 units (20 mg).
Price vials of 15 mg (1 ml) - 10 pieces 1009 rubles buy solution for injections by 5 mg (1 ml) for 629 rubles possible.
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