Monday, October 29, 2018

Adolescents with overweight are more prone to cancer of the esophagus

October 17, 2013

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 Adolescents with overweight are more prone to cancer of the esophagus  Those teenagers who tend to be overweight in the future about twice as likely to suffer esophageal cancer Than teens who have always been a normal weight. Such findings made by Israeli doctors, guided by the results obtained in recent studies. They learned about a teenager who was about 17 years old. Researchers compared the body mass index of teenagers with national statistics on the incidence of cancer.

It was found that the risk of cancer was higher among those adolescents who were overweight. Also, a higher incidence was observed among representatives of sectors of the population with a low socio-economic status.

Scientists believe that the main cause of these indicators are particularly diet. The development of cancer illnesses affect the consumption of too much salt, and smoking.

So far, researchers have not in a hurry to talk about whether the risks will reduce the incidence of weight loss. However, doctors are unanimous: to improve overall health outcomes and adolescents, and older people should be sure to reset the weight of hardship. Moreover, it is best to do this with the help of daily physical activity. And in order to play sports, do not necessarily need to go to gyms.

Recently, experts expressed the view that even the most " advanced "Simulators allow you to get a much lower effect on employment than the usual basic exercises, in which the load is achieved by the weight of the person. This push-ups, pull-up, and other well-known throughout the exercise. If you regularly at least three times a week to train, doing these exercises 20-30 minutes , The physical form is excellent. By performing these exercises, you can not only lose weight but also improve motor skills, increase the performance of balance and mobility. The so-called everyday movements allow use several muscle groups at once and at the same time a positive impact on job Cardiovascular .

Silest

Description overdue on 29.03.2012

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 Silest  Contraception . It is a combination drug, the composition comprises two active components: norgestimate   and ethinylestradiol . The drug suppresses Ovulation   due to inhibition of synthesis gonadotropins , Suppression of work hypothalamic-pituitary system . Silest implantantsionnuyu able to change the ability of the endometrium, reducing transport function of the fallopian tubes, increases the viscosity of cervical mucus. Available in tablet form.

Indications and contraindications:

Silest prescribed as a contraceptive. The drug is not used with a deficit of antithrombin 3, thromboembolism . thrombophlebitis , Norgestimate and ethinyl estradiol intolerance. Silest contraindicated in breastfeeding, endometrial tumors, breast, when estrogen dependent tumors, sickle-cell anemia, pregnancy, cerebrovascular disorders, tumors of the liver, liver failure, severe course Diabetes , Liver tumors, high blood pressure, bleeding of the genitourinary system, coronary heart disease, cerebrovascular diseases , Lipid metabolism disorders, mononucleosis, otosclerosis , Hemolytic anemia. When uterine fibroids ulcerative colitis , Liver disease, tuberculosis . mastitis , Depression, kidney disease system, epilepsy, adolescents administered with caution.


Side effect:

Silest can cause eating disorders, worsening cholelithiasis , Breast tenderness, nausea, vomiting, high blood pressure, chloasma, decreased libido , Changes in body weight, fluid retention, depression, headache, worsening of renal diseases system.

Mode of application:

Silest pills taken orally. To start the treatment on the first day of the menstrual cycle. The drug is taken daily for 20 days to 1 tablet then does not take the medication for seven days. During this period the woman should appear menstrualnopodobnye bleeding. After a seven-day break, the cycle of the drug is resumed. Silest desirable to take at the same time every day.

Special instructions:

After completion of dosing Silest women's reproductive function is restored, the sex glands start working in full and the usual mode, providing full and healthy birth .  Use of the drug after a miscarriage, abortion, childbirth is recommended to begin after the first menstrual cycle .  Before therapy, and every six months, you must undergo a gynecological, general medical examination, including blood pressure monitoring, urinalysis, cholesterol levels, the study of mammary glands, liver .  At the initial stage of the drug while breastfeeding may experience a decrease in the amount allocated milk .  Silest excreted in breast milk in small amounts .  Women with nicotine dependence when taking oral contraceptives increased risk of developing cardiovascular disease (severe complications can not be excluded as a heart attack . stroke ). The risk depends on the age and number of cigarettes smoked per day. Vomiting and diarrhea, there is a decrease contraceptive action of the drug. If pregnancy occurs the treatment of an emergency stop. An increase in blood pressure, retrosternal pains, stabbing pains in the lungs and coughing, cerebrovascular disorders, visual impairment, occurrence of jaundice, phlebothrombosis, the first sign of phlebitis priemenie drug Silest stopped. While receiving the drug may cause bleeding that does not require discontinuation of therapy. When strongly pronounced bleeding necessary to gynecological examination. Regular intake of alcoholic beverages leads to a decrease in efficacy Silest.

Drug Interactions:

Phenytoin, carbamazepine , Antiepileptics, barbiturates, pyrazolone derivatives, sulfonamides   may increase the metabolism of steroid hormone medication. When concomitant administration of antibiotics (eg, rfampitsin, ampicillin, etc.) there is a decrease contraceptive effectiveness, due to changes in the intestinal microflora, and requires the use of additional methods for protection against unwanted conception. Use of a progestogen-estrogen drugs require dose adjustment hypoglycemic agents .

Enterosgel

Description overdue on 02-02-2012

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 Enterosgel  Enterosorbiruyuschee means.   The active substance acts hydrogel methylsilicic acid . The drug has Enterosgel detoxification, enveloping, enterosorbiruyuschee impact. The medicament adsorbed from the alimentary tract, blood incorporated radionuclides Viruses, allergens Products of incomplete metabolism, toxic substances. The drug improves the functioning of liver and renal systems, normalize intestinal function, eliminates signs toxemia And accelerate repair processes   mucosal lumen, stimulates removal of microflora and pathogens from the gut lumen. Enterosgel activate peristalsis   digestive tract, promotes membrane digestion, does not affect saprophytic microflora . Available in the form of paste and gel.

Indications and contraindications:

Enterosgel prescribed for intoxications of various origins: the poliksitoze kidney . pyelonephritis , Glomerulonephritis, septic states, alcohol intoxication, diarrhea, SARS . radiation injury , Preeclampsia, dermatitis, bronchial asthma, burn disease. Drug sverdstvo effective in diseases of the digestive tract: syndrome "irritable" bowel   ulcerative colitis . enterocolitis , Ulcerative lesions of the gastrointestinal tract, and hypoacid giperatsidnom gastritis, cirrhosis . cholestasis , With post-resection syndrome after surgery on the gastrointestinal tract. Enterosgel is contraindicated in case of intolerance methylsilicic acid hydrogel.


Side effect:

In severe renal or hepatic pathology systems marked aversion to the drug through 2-3 hours. Flatulence, nausea and strengthening dyspeptic disorders is recommended to discontinue use of the drug.

Mode of application:

Enterosgel take three times a day recommended by the reception - two hours before a meal, it is permissible use enterosorbent a half hour after the meal. The drug must be thoroughly mixed in the ratio 1: 2 with water to obtain a homogeneous suspension. Depending on the stage and severity of the disease course of treatment can last from seven days to two weeks. For persons older than 14 years and adults single dose is 15 grams, which corresponds to 1 tablespoon. Children 7-14 years should take enterosorbent 1 dessert spoon, which corresponds to 10 grams of the drug Enterosgel. The daily dosage for adults is 45 g, for children - 15 grams. In severe underlying disease first three days of detoxification therapy take a double dose of the drug. In cirrhosis of the liver, obstructive jaundice   enterosorbiruyuschee means taking for six months. With ARI 15 grams of gel diluted with 200 ml of water for gargling.

Special instructions:

The first days of receiving the drug Enterosgel may be accompanied kratvovremennymi constipation . Individuals who are prone to constipation, it is recommended to do cleansing enemas . The drug can be taken during breastfeeding, pregnancy. After opening the package Enterosgel should be stored in gerpetichnoy container, protected from drying out. Sold in pharmacies without a doctor's prescription items.

Drug Interactions:

Enterosgel can be used in combination with other medicines, in compliance with the required time interval between doses. The drug can be combined with immunomodulators . adaptogens , Herbal remedies, bacterial agents (lactobacilli, bifidobacteria, lactobacilli, Lactobacillus).

Ketoconazole

Description overdue on 16.05.2012

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 Ketoconazole  Antifungals   It affects yeasts, dermatophytes , Eumitsety, dimorphic fungi, as well as streptococci and staphylococci. The principle is based on the impact of violations of the permeability of the cell wall, inhibiting the process of synthesizing enzyme ergosterol   in the membrane of the fungus. The drug does not affect the Zygomycetes, the causative agent of aspergillosis. Under the influence of the drug ketoconazole reduces education androgens . Ketoconazole is available as tablets and capsules.

Indications:

Ketoconazole prescribed for fungal infections of the digestive system, reproductive organs, eyes, recurrent course vaginal candidiasis When ringworm, trihofitii, systemic fungal infections, thrush, onychomycosis, folliculitis, histoplasmosis, cryptococcosis, kotsidioidoze, paracoccidioidomycosis, candidiasis, blastomycosis, chromomycosis, fungal pneumonia , Fungal sepsis, paronychia, sporotrichosis, leishmaniasis, with pityriasis versicolor . The drug is prescribed for hirsutism , Kashin-Beck's syndrome, prostate cancer, for preventing fungal infections.

Contraindications:

Ketoconazole is not used during pregnancy, hypersensitivity, breastfeeding. When alcoholism, hypochlorhydria, achlorhydria, taking hepatotoxic drugs a drug used with caution.


Side effect:

Digestive system : Toxic hepatitis, diarrhea syndrome, constipation , Nausea, dyspepsia , Decreased appetite, vomiting, hypercreatininemia.   Nervous system:   paresthesia , Increased drowsiness, headache, dizziness. Urogenital:   impotence, oligospermia, gynecomastia, azoospermia, dysmenorrhea , Decreased libido in males. Bodies of blood:   hemolytic anemia, thrombocytopenia, leukopenia. Perhaps the development of allergic reactions in the form of photophobia, rash, skin rash, lihoralki, urticaria. Rarely observed alopecia.

Mode of application:

Capsules and tablets ketoconazole taken during meals, by mouth. Multicolored versicolor, ringworm: 1-8 weeks for daily 200-400mg. Onychomycosis: 3-12 months of 200-400mg daily to the normalization of laboratory data, a full recovery. Systemic mycoses: 2 weeks 200-40 mg per day, followed by 4-6 weeks of 200 mg. Vulvovaginal candidiasis: 3-5 days 200-400 mg daily. Paronychia: 200-400 mg per day. Fungal pneumonia, sepsis: 400-1000mg day. Kashin-Beck Syndrome: 600-1200 mg per day. In systemic mycosis duration of therapy is 6 months, in some cases longer.

Special instructions:

During antifungal therapy requires regular monitoring of the state of renal, hepatic systems, peripheral blood. If therapy is skin fungal disease begins with glucocorticoids, ketoconazole is used only two weeks after the cancellation of glucocorticoids. Patients with hypochlorhydria , Achlorhydria drug may be ineffective because of reduced absorption of the main substance. By drinking acidic drinks increases the absorption of the drug.

Drug Interactions:

Hepatotoxic drugs, ethanol increases the likelihood of damage to the liver parenchyma. Acceptance of alcoholic beverages can trigger the development of disulfiramopodobnyh reactions. Ketoconazole increases the likelihood of hypoglycemia It increases the level of sulfonylurea derivatives. Isoniazid . rifampicin   lower content of the drug in the blood. Ketoconazole weakens the effectiveness of amphotericin B. The drug increases the concentration of methylprednisolone, anticoagulants , Cyclosporine, triamzolama, midazolam, digoxin. Ketoconazole reduces the stimulating effect on the adrenal corticotropin, increases the bioavailability of the drug indinavir. In combination with astemizole, terdenadinom, cisapride increases the risk of severe Ventricular tachycardia   like "feast." In appointing oral contraceptives   increases the likelihood of bleeding "breakthrough". The drug increases the toxicity of phenytoin. Anticholinergic drugs, antacids, H2-blockers of histamine receptors reduce the acidity of gastric juice, which reduces the absorption of the ketoconazole.

Pikolaks

Description overdue on 04/09/2014

  • Latin name: Picolax
  • ATC code: A06AV08
  • Active substance: Picosulphate Sodium (Sodium picosulfate)
  • Manufacturer: "Farmak", Ukraine
Photos of the drug
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Contraindications
  • Side effects
  • Instructions on Pikolaks (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Analogs
  • With alcohol
  • Reviews
  • Price, where to buy

 Pikolaks

Composition

The drops for oral use 0 contained 75% active ingredient: sodium picosulphate   - 7, 5 mg / ml and auxiliary substances: sorbitol, hydrochloric acid, sodium methyl hydroxybenzoate   and purified water.

Each tablet contains Active ingredient:   sodium picosulphate   in terms of 100% anhydrous substance 5 mg or 7 mg 5 and auxiliary components: lactose monohydrate , Corn starch and pregelatinized 1500 magnesium stearate, colloidal anhydrous silica.

Product form

This drug comes in drops for oral use 15 or 30 ml vials. Also in tablets of 10 pieces in the package, placed 1-3 in a cardboard blister pack.

Pharmacological action

Tablets and drops Pikolaks have a contact laxative effect.

Pharmacodynamics and pharmacokinetics

When treating Pikolaksom Ingestion its active ingredient   sodium picosulphate   It has a beneficial effect on the large intestine. Under the influence of bacterial flora of the drug is cleaved to form the active form - free diphenol .

Then the stimulation of sensory nerve endings of the intestinal mucosa, increase its motility. Receiving this medication is not causing tenesmus and   enterospasm .   Development of laxative effect occurs after 6-12 hours after a single dose application.

During treatment, infants marked lack efficacy, because they have a small amount of bacterial flora, generating sulfatase .

Indications

Pikolaks prescribed to patients in the case of:

  • atonic constipation Due to a change in power, prolonged immobilization, severe general condition, fever , Metabolic disorders and diseases of the cardiovascular system;
  • preparation for surgical and gynecological operations, as well as instrumental research;
  • adjust the chair at hemorrhoids   and Cracks in the anus .

Contraindications

It is not recommended to use the drug in any form:

  • increased individual sensitivity to the drug;
  • obstructive bowel obstruction . nausea . vomiting , Abdominal pain of unknown etiology and complicated by dehydration;
  • acute surgical abdominal pathology and after surgical interventions on the digestive tract.
  • lactation pregnancy.

Drops Pikolaks not prescribed for:

  • fructose intolerance .

Tablets are contraindicated in patients with:

  • lactase deficiency, galactosemia   and glucose-galactose malabsorption ;
  • under the age of 10 years.

Caution should be exercised in treating patients with hypokalemia . gipermagniyemy   and elderly patients.

Side effects

As the clinical practice, Pikolaks well tolerated by patients of different age groups. However, one should not exclude the development of side effects such as: indigestion . diarrhea . vomiting . nausea . intestinal colic . flatulence, pain in the anal area.


Also available: headaches, sleep problems, seizures, severe fatigue, tremor, various allergic reactions   and so on.

Long-term use of the drug contributes to addiction and Development constipation Which has the effect of " ricochet ". To avoid the development of undesirable symptoms are advised to take the drug once or short-term.

Instructions on Pikolaks (method and dosage)

It should be noted that the drop Pikolaks, instruction on the application recommends the evening. Young patients this form of the drug can be added to food. For accurate dosing of the drug is a special dispenser on the bottle. The duration of treatment and the dosage determines physician for each patient, taking into account his individual characteristics. Typically, for adults and adolescents of 10 years prescribed daily dose of 13-27 drops. Children aged 4-10 years is assigned an average daily dose of 7-13 drops of the drug. In the treatment of children up to 4 years of dispensing the drug is calculated by a special formula 250mkg / kg of the total weight of the child, ie 2 drops Pikolaksa per 3 kg body weight - once a day.

Patients with oncological diseases Who receive treatment with opioid analgesics, the dosage is calculated as the attending physician. In any case, it is not recommended to take a drop of more than 3 consecutive days.

Tablets Pikolaks recommended swallowed in whole with some liquid. The drug is prescribed for use in the morning or evening. Duration of therapy and dose sets for treating any particular patient. For adults and adolescents from 10 years to designate the average daily dose - 1 tablet. If necessary, the dose is increased to 2 units per day. The therapeutic course can not last more than 10 days.

Overdose

In case of overdose Pikolaksom patients may develop: diarrhea, pain in the stomach, reducing the level of potassium in the blood and other violations of water-electrolyte balance.

It is also not excluded ischemia mucosal colon. If the drug is used in high doses for a long time, it can occur in patients with: chronic diarrhea, intestinal cramps, hypokalemia , Renal failure, secondary hyperaldosteronism, urolithiasis disease   and metabolic acidosis . Hypokalemia can cause muscle weakness.

In such cases, usually assigned gastric lavage, reception enterosorbents and conduct further symptomatically.

Cooperation

Concomitant use with corticosteroids Pikolaksa or diuretic drugs increases the risk of water and electrolyte balance. Admission antimicrobial broad-spectrum in combination with a laxative effect Pikolaksom reduce its active ingredient - sodium picosulphate .

Terms of sale

The drug is available without prescription.

Storage conditions

Keep the medication you need in a place protected from the light and children, at a temperature of 25 degrees C.

Shelf life

Any form of the drug can be used within 3 years from the date of issue, subject to the conditions of storage. However, a drop Pikolaks after opening the bottle can be used no more than 28 days.

Analogs

Drugs with similar action are: Guttalaks, bisacodyl, Castor butter   and Senade .

Alcohol and Pikolaks

Experts do not recommend during treatment Pikolaksom abuse alcohol. The fact that alcohol slows down the reaction of the person, so it may just not notice the signal to empty the bowel.

Reviews Pikolakse

This drug is very popular among patients of different age groups. Therefore, reviews of Pikolakse can be found at medical forums discussing the problems of digestion and GI tract. In addition, users often say that this drug is used to treat children. It is successfully used in the treatment of constipation during dizbakterioza   and other problems. Many people say its high efficiency, which facilitates the intestine in a short time.

Quite often the drug used by patients suffering chronic digestive disorders . Unfortunately, they often experiment with the dosage or injected additional funds. As a result, they have side effects, mainly in the form of diarrhea. Therefore, experts recommend to abandon the self and to adhere strictly to doctor's appointments.

Price Pikolaksa where to buy

In Moscow, the price Pikolaksa tablets   It is from 49 rubles.

The drug in the drops   can be purchased at the price of 185 rubles.

Get the best price and buy

Saturday, October 27, 2018

Eufillin

Description overdue on 02/10/2013

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 Eufillin  Bronchodilator. Active component - aminophylline. The mechanism of action of the drug is aimed at blocking purine (adenosine) receptors increase cAMP accumulation in the tissues, the inhibition of phosphodiesterase, reducing the contractility of the smooth muscle, decrease in revenues through the channels of the cell membrane calcium ion. The main ingredient is a derivative of purine. The drug increases renal blood flow , Renders vazodilatirtee peripheral the impact of, renders a moderately expressed diuretic effect , Relaxes the smooth muscle of blood vessels (mainly kidneys, skin, brain), bronchi.

Under the influence of the drug reduced the rate of release of mediators of allergic reactions to stabilize the membrane of fat cells, stimulates the respiratory center, improving the operation of the intercostal muscles and respiratory muscles, stimulates contraction of the diaphragm It increases mucociliary clearance. Electrophoresis aminophylline has vasodilatory, anti-inflammatory, resolving and analgesic effects. The medicament reduces the level of carbon dioxide in the blood, and its oxygen saturation, respiratory function by normalizing.

With hypokalemia   medication enhances ventilation. Eufillin tissue increases the need myocardial oxygen increases   coronary blood flow Increases heart rate and heart rate, stimulates the functioning of the heart, lowers the tone of the blood vessels, lowers blood pressure in the pulmonary circulation, reduces pulmonary vascular resistance, inhibits platelet aggregation rate, expanding the lumen of the bile duct, normalizes microcirculation It improves blood rheology, reduce thrombosis, increases resistance to deformation of erythrocytes. Aminophylline produced in tablet dosage form, capsules, suppositories, solution.


Indications:

Drug Usage Eufillin recommends prescribers at broncho-obstructive syndrome : COPD ( emphysema , Chronic obstructive bronchitis), asthma; at Sleep apnea , Edema syndrome on the background of renal pathology system in "pulmonary" heart, pulmonary hypertension . Indications for parenteral administration Eufillin: left ventricular failure with respiratory failure by type of Cheyne-Stokes and bronchospasm, disorders of cerebral circulation on ischemic type, apnea in newborns, asthmatic status .

Contraindications:

Eufillin not prescribed for epilepsy, intolerance to theophylline, ulcers of the digestive tract and in severe hypertension or hypotension, gastritis with high acidity, hemorrhagic stroke, heavy tachyarrhythmias , With hemorrhages in the retina of the eye. Eufillin children up to 3 years is not appointed. During pregnancy, prolonged hyperthermia, severe coronary insufficiency, with increased convulsive readiness, chronic heart failure , Frequent ventricular arrhythmia, disseminated atherosclerosis, angina pectoris, acute myocardial infarction, uncontrolled hypothyroidism , Recent bleeding from the digestive system, breastfeeding, prostatic hypertrophy, thyrotoxicosis, gastroesophageal reflux Eufillin used with caution. Rectal form of the drug is not indicated for diseases of the colon and diarrhea.

Side effect:

Nervous system:   limb tremor, agitation, dizziness, anxiety, insomnia , Headaches, irritability. Cardiovascular system:   increased frequency of angina attacks, cardialgia , Drop in blood pressure, arrhythmia, tachycardia, palpitations. The digestive tract:   diarrhea, exacerbation of peptic ulcer disease, gastroesophageal reflux disease , Nausea, gastralgia, heartburn , Violation of appetite, vomiting. Perhaps the formation allergic Answer in the form fever, itching, skin rash . The treatment may increase urine output, feeling the tides-to-face, tachypnea , Chest pain, hematuria, albuminuria , Increased sweating, hypoglycemia. By reducing the dosage of the drug observed decrease in the severity of side effects.

Overdose:

Manifested by diarrhea, stomachalgia , Anorexia, tachypnea, motor excitation, cramps, photophobia, anxiety, tremor of the extremities, tachycardia , Flushing of the skin face, gastrointestinal bleeding, vomiting, nausea, ventricular arrhythmias, insomnia . In severe poisoning are recorded epileptic seizures , Drop in blood pressure, hypokalemia, hyperglycemia , Sputannosti of consciousness, necrosis muscle tissue, hypoxia, renal failure with myoglobinuria, metabolic acidosis .

Requires gastric lavage and bowel combination of polyethylene glycol and electrolytes, appointment enterosorbents, symptomatic therapy, hemodialysis, plasma sorption, hemosorption, forced diuresis . With the development of seizures carried out oxygen therapy Provide an open airway. For relief of an attack intravenous 0, 1-0, 3 mg / kg of diazepam. If severe vomiting and nausea administered ondansetron and metoclopramide.

Mode of application:

Average dose - 300 mg twice daily. Eufillin drug treatment is initiated with smaller dosages, gradually increasing the amount of drug to achieve the desired therapeutic effect. Dose picked individually depending on the age group of the patient's weight, the nature and course of the disease pulmonary system, comorbidity. Maintenance dose for adults weighing 60 kg is 600 mg / day; less than 60 kg - 400 mg / day.

When liver disease and diseases of the cardiovascular system prescribed daily dosage of the drug Eufillin - 400 mg. Elderly patients with heart disease, liver and concomitant viral infection reduced the daily dose of medicament. For patients with reduced clearance of theophylline prescribed initial dose - 250 mg per day, 2 days the amount of drug increased to 500 mg per 1 reception. Eufillin ampoules is administered intravenously saline.

Special instructions:

Tablets retard not apply for emergency relief emergency conditions. We recommend caution when taking caffeine drinks and food in large quantities during the treatment. With good control of bronchial asthma and in the absence of pronounced side effects, correction mode 1 is performed every 6-12 months. Therapy prolonged forms of the drug is carried out under mandatory supervision in the blood levels of theophylline. Eufillin at pregnancy applies only under vital indications.

Drug Interactions:

The absorption of the drug decreases as the reception enterosorbents   and antidiarrheal agents. The probability of side effects increases with concurrent therapy glucocorticosteroids , ISS (developing hypernatremia ), Drugs that stimulate the central nervous system, drugs for general anesthesia (developing ventricular arrhythmias).

Moratsizin, estrogensoderzhaschie oral contraceptives, aminoglutethimide, carbamazepine, phenytoin, rifampin, sulfinpyrazone, isoniazid, phenobarbital are inducers of microsomal oxidation and can improve the clearance of theophylline, which may result in the need to increase the dose. Simultaneous therapy inhibitors of cytochrome P450 (disulfiram, enoxacin, cimetidine, allopurinol,   linkomitsin Macrolides, mexiletine, verapamil, ticlopidine, thiabendazole, propafenone, methotrexate, recombinant interferon alpha, isoprenaline, fluoroquinolone) enhanced efficacy of theophylline, which necessarily require dose reduction.

Eufillin reduces efficiency beta-blockers , Drugs lithium, the opposite effect is observed in the treatment of diuretic drugs, and beta-agonists. The drug is not used in conjunction with other xanthine derivatives. The drug is compatible with antispasmodics. If necessary, use anticoagulants   the drug is prescribed with caution.

Chronic gastritis

September 12, 2011

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 Chronic gastritis  Gastritis   is an inflammation of the lining of the intestinal wall. Provided 2 forms of gastritis - acute , Rapidly flowing and chronic Flowing with frequent relapses. Chronic gastritis - a disease caused by chronic inflammation of the mucosa of the inner wall of the stomach and impaired production of hydrochloric acid, which leads to the degeneration and restructuring envelope. The disease not only leads to pain, to a violation of the process of digestion, but also to a decrease in efficiency, appearance of irritability, fatigue. The main forms of chronic gastritis are A chronic autoimmune gastritis   (up to 5% of all cases) and In chronic gastritis   (85% of cases caused by the bacterium Helicobacter pylori ), Other forms of gastritis occurs much less frequently.

Chronic gastritis A proceeds with the normal secretion gastric But when the recess is a reduction of inflammation of gastric juice. Hemorrhagic (erosive) gastritis is accompanied by stomach bleeding , Occurrence of erosion on the gastric mucosa, while maintaining gastric secretion. Rigid gastritis   characterized by inflammatory and scar changes antrum, its restriction. An independent form of gastritis is considered and reflux gastritis . Conventionally, to include chronic gastritis Giant hypertrophic gastritis   (or disease Menetries ). In addition, there are gastritis with low and high secretory activity.


Chronic gastritis - very widespread disease, which affects more than 50% of the adult population of the planet, and among diseases of the stomach is 85%.

The disease is the result of acute gastritis, but often it causes are:

  • eating disorders, eating cold food, eating spicy foods, excessive consumption of alcoholic beverages;
  • Malnutrition (deficiency of proteins, vitamins), food intake, which contains emulsifiers, preservatives, refined oil;
  • smoking;
  • stress, which leads to disruption of the normal rhythm of life, such as work at night;
  • long-term use of medicines that are irritating to the mucous membrane of the stomach;
  • Adverse factors associated with the production (metal dust, lead compounds);
  • genetic predisposition;
  • the impact of toxic products of disturbed metabolism ( diabetes );
  • chronic infectious disease ( syphilis . tuberculosis ).

In the majority of cases of chronic gastritis in the accompanying Chronic colitis . cholecystitis   and appendicitis .

Symptoms of chronic gastritis

 Chronic gastritis  Chronic gastritis A has no specific symptoms and the clinical picture of the disease is quite diverse. In chronic gastritis with secretory deficiency, the most common symptoms are a feeling of fullness, aching pain in brief epigastric Especially during and after the meal. Other common symptoms of chronic gastritis dyspeptic symptoms - nausea, vomiting, heartburn , Regurgitation, sour taste in the mouth. Also, patients may experience rumbling in the stomach, flatulence , Violation of the chair. On palpation of the epigastric region may be painful.

If chronic gastritis occurs in a normal or an increased secretion of gastric juice, it is considered surface And occurs more frequently in men at a young age. In this case, patients plagued by abdominal pain, acid regurgitation, heartburn, feeling of heaviness in the stomach after eating, constipation . Pain can also occur at night.

After contact with the bacterium Helicobacter pylori in the stomach, it starts to actively proliferate, which leads to a change in the normal production of gastric juice, and the emergence of erosion and stomach ulcer .

The general condition of the patient is usually not affected, but in chronic gastritis with insufficient secretion of gastric juice can be observed weight loss, fatigue.

Very often a patient with symptoms of chronic gastritis, liver disease, bowel, pancreas, but in this case gastritis is a consequence of these diseases.

Diagnosis of chronic gastritis

If you suspect gastritis doctor assigns holding ultrasound and X-ray inspection, as well as esophagogastroduodenoscopy During which you can spend gastric mucosal biopsy to detect helicobacter pylori bacteria. Diagnosis of chronic gastritis includes the study of gastric secretion by intragastric pH-metry   or by sensing frakionnogo . Informative method in the diagnosis of chronic gastritis is gastroscopy . With it you can see the big picture of gastritis - the nature of the pathological process, its localization and distribution.

However, the final diagnosis puts a gastroenterologist based on a comprehensive assessment of clinical and laboratory findings. It is important to rule out other diseases, such as ulcer . benign tumors of the stomach   etc.

Treatment of chronic gastritis

 Chronic gastritis  Generally, treatment of patients with chronic gastritis is conducted on an outpatient basis, and hospitalization is necessary in cases of acute illness and difficulties in diagnosis.

If during the tests the patient has been identified in chronic gastritis caused by the bacterium Helicobacter pylori, the doctor appoints conduct eradication therapy Aimed at destroying bacteria. In this case, for 7-10 days under the special scheme adopted two kinds of antibiotics and antisecretory drugs ( lansoprazole . omeprazole ). Eradication therapy is a reliable way to deal with the bacterium.

During flare-appointed special diet . A gastroenterologist or nutritionist will help you choose the most suitable diet and a list of recommended dishes.

Treatment of chronic gastritis diet therapy depends on the type of gastritis, gastric secretory function of the state and the phase of the disease, and should take into account the concomitant diseases of the liver and biliary tract, intestines, as well as anemia, vitamin deficiency.

Power fractional recommended, 5-6 times a day. During the first day of exacerbation refrain from eating, after switching to diet food - jelly, soups frayed. Food should be thermally and mechanically gentle, it can not be smoked, sour, food, drink only in the form of heat. At the same time prescribe medications, enveloping the stomach wall, and adsorbs toxins.

When gastritis with normal or elevated secretion of gastric juice nutrition is aimed at eliminating inflammation in the gastric mucosa and the normalization of its work. In this case, a nutritionist appointed Diet # 1a   (up to 7 days), then - Diet №16   (up to 14 days), and is stretched by 3 months Diet №1 . Under these diets provide food to the patient in a liquid or a shabby, further added vitamins ( ascorbic acid . riboflavin ). Prohibited use of alcohol, juice, coffee, strong tea, acute fatty foods, canned goods, beans, peas.

In chronic gastritis with insufficient gastric secretion, diet aims to reduce inflammation in the stomach and its stimulation of the glandular system. In this case, compliance is shown diet №2 Which provides shchazhenie chemical stimulation gastric secretory activity. The body gets an increased amount of vitamins ( riboflavin . retinol ) And a sufficient amount of salt. Food in this case, a fraction, the food is well accepted in the grinding and thoroughly boiled form, and reception coffee, tea, juices, vegetable Nawar, broth, meat and low-fat varieties of fish provides stimulation of gastric secretory function. Due to insufficient production of gastric juices from the diet excludes foods that are rich in fiber, namely grapes, radishes, dates, as well as sharp, smoked and very salty food, cold drinks, pastry. Not recommended for whole milk, cream, porridge made of buckwheat and pearl barley, beans, pickled vegetables, mushrooms, soft drinks.

In periods of relapse is patients with chronic gastritis A constantly recommended diet, limiting themselves in alcohol, coffee, spicy, hot dishes, marinades, canned. Such prevention of chronic gastritis avoids frequent exacerbations.

During an exacerbation of autoimmune gastritis but appointed replacement therapy   - Drugs that stimulate the production of gastric juice, hydrochloric acid preparations. For stimulation of gastric secretion in the diet included strong broths, meat and vegetable soups, lean meat, fish, vegetables, fruit. At the same time passes and the treatment of anemia.

Bile reflux gastritis   It requires careful diet. The basic diet is made, as in the liver, during exacerbations prescribe chronic gastritis antacids   ( Maalox . almagel ), Appointed as preparations for the neutralization of bile acids   ( ursodeoxycholic acid . cholestyramine ), And to normalize gastrointestinal motility - metoclopramide drugs   ( raglan . Reglan ).

When treating hypertrophic gastritis   appointed high-calorie diet rich in proteins.

Drug treatment of chronic gastritis is conducted at an exacerbation of the disease. Patients with chronic gastritis in the period of acute appointed antacids   ( Rother . vikalin . almagel ). To resolve dyspeptic symptoms using drugs metoclopramide ( Reglan ). In chronic gastritis with insufficient production of gastric juice designate of vegetable origin, which have anti-inflammatory properties: camomile, St. John's wort, peppermint, Valerian .

From physical therapy methods in complex treatment of exacerbations of chronic gastritis, used electrophoresis novocaine And various heat treatments, as well as diadynamic modulated currents . Physical therapy   reduces symptoms of chronic gastritis, and normalize motor function of the stomach.

Patients suffering from chronic gastritis should be under medical supervision and checkups 2 times a year to adjust therapy and dietetics.

Prevention of chronic gastritis

Prevention of chronic gastritis is to prevent its relapse. It is important to observe the correct diet and rest, timely treatment of opportunistic diseases, elimination of overeating, alcohol, smoking, long-term use of certain medications.