Description overdue on 05/06/2014
- Latin name: Ornidazole-Vero
- ATC code: G01AF06
- Active substance: Ornidazole (Ornidazole)
- Manufacturer: OJSC "Veropharm", Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Reviews
- Price, where to buy
Composition
The composition of one tablet of the drug:
- ornidazol ;
- MCC, corn starch, sodium carboxymethyl PVP, magnesium stearate.
The shell consists of the following components: PVP, titania, Tween-80, hydroxypropylmethylcellulose Talc.
Product form
Ornidazole medicament Vero available as white round tablets, which are coated with a film coating. The cardboard packaging is a blister containing 10 tablets.
Pharmacological action
Renders protivoprotozoynymi action .
Pharmacodynamics and pharmacokinetics
Ornidazole Vero - preparation rendering antiprotozoal effect, as well as having antibacterial activity. Acts by reducing 5-nitro ornidazole, which then interacts with cell DNA synthesis reducing acids, whereby the bacteria are killed.
Active against: Giardia intestinalis, Gardnerella vaginalis, Trichomonas vaginalis, Histolytica Entamoeba . As the drug is able to withstand an obligate anaerobic organisms ( Bacteroides spp. . Fusobacterium spp., Prevotella spp., Veillonela spp. ) And Gram-positive microorganisms ( Clostridium spp., Clostridium spp. ).
Not effective against aerobic microorganisms.
Easily absorbed from the digestive tract, bioavailability of 90%. It reaches a maximum concentration at 1, 5-2 hours. 60% is excreted in the urine, 21% - with the feces as metabolites, unchanged output of about 5%.
Indications
The drug is prescribed in the following cases:
- giardiasis ;
- amoebiasis ;
- amebiasis (including extraintestinal);
- trichomoniasis ;
- prevention of infection, which may result from the action of anaerobic bacteria;
- gynecology;
- during surgery on the colon.
Contraindications
The drug is contraindicated in central nervous system diseases . It is also not recommended to use it during I trimester of pregnancy . breast-feeding and sensitivity to any component of the medication (including nitroimidazole derivatives).
Side effects
Treatment according to the drug may cause the following side effects:
- dizziness , Discoordination movements, impaired consciousness, seizures, rigidity , headache, tremor . peripheral neuropathy ;
- nausea, diarrhea, vomiting.
Instructions for use (method and dosage)
Take Ornidol Vero should be inside, immediately after a meal.
With trichomoniasis children should take a dose of 0, 25 g per kg body weight once; adults - twice a day for 0, 5 g For adult treatment - 5 days.
With amoebic dysentery children and adults (weighing 35 kg) must take a day 1, 5 g, with a weight over 60 kg - 2 g children who weigh less than 35 kg taking medication 40 mg per 1 kg weight. Continue treatment should be 3 days.
In the presence of other forms of amebiasis children and adults (weighing 35 kg) must be taken twice a day 0, 5 g, weighing less than 35 kg - 25 mg per 1 kg body weight (once). Continue treatment should be from 5 to 10 days.
With giardiasis children (weighing 35 kg) and adults administered on day 1, 5 g, weighing less than 35 kg - 40 mg per kg body weight. Continue treatment should be 2 days.
To avoid complications which can be caused by anaerobic bacteria, after the operation, before the operation should take 0, 5 g, and then for a period of 4-5 days every 12 hours of taking the medication on 0, 5 g
Overdose
Symptoms of overdose: depression . epileptiform convulsions . peripheral neuritis . If you experience these symptoms, symptomatic treatment.
Cooperation
The drug Ornidazole Vero able to enhance the action anticoagulants kumirinovogo series Increase the effect of vecuronium bromide .
When combined with ethanol Ornidazole not inhibit acetaldehyde dehydrogenase.
Terms of sale
Prescription.
Storage conditions
Store must be in a place sheltered from light and moisture, the average temperature around 25 degrees Celsius.
Shelf life
It is recommended not to store more than 2 years.
Cautions
The course of treatment must be assigned for both partners during sex trichomoniasis .
Reviews on Ornidazole Vero
Many patients in their reviews they write about the weak and strong efficacy of side effects.
Price Ornidazole Vero
The price of the drug in Russia is about 137 rubles, Ukraine - 21 UAH.
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