Vitamin B3 (niacin)

December 9, 2011

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Vitamin B3   (a nicotinic acid) - vitamin , A drug that is involved in many cellular oxidative reactions. Until 2008, Russia has been used as a dietary supplement, but it is now banned.

The main functions of niacin:

Participation in the metabolism amino acids . proteins . fat . Maintaining the biosynthesis. The normalization of tissue respiration. Provide glycogenolysis   - The reaction which takes place in the muscles and liver. It normalizes blood lipoprotein levels. Can reduce the concentration cholesterol   priyant blood at high doses (3 g / day).

• It has antiatherogenic effect
• Vasodilation, mainly small (including the brain)
• It has anticoagulant effect
• It improves the microcirculation
• It improves fibrinolytic activity Blutwurst
• Enhancing vasodilator drugs
• Regulates blood glucose
• Maintaining healthy skin

Sources of Vitamin B3:

• Meat, kidney, liver
• Bread
• Beans, buckwheat
• Mushrooms
• Pineapples

Need

15-20 mg of daily need of nicotine acid.

Indications

To receive vitamin B3, there are many indications among which are: an unbalanced and inadequate diet, malabsorption (including due to violations of the pancreas), pellagra (a disease caused by poor diet), the disease Hartnupa (malabsorption of amino acids) rapid weight loss, persistent diarrhea Crohn's disease, gluten enteropathy, gastrectomy, cirrhosis of the liver   and chronic hepatitis , Prolonged fever, chronic infection, hyperthyroidism . pregnancy . lactation . malignancy , Hyperlipidemia, sores and festering wounds, colitis , Hypoacid gastritis, neuritis of the facial nerve, circulatory disorders in the brain, diseases and vascular spasm , Microangiopathy, diabetic polyneuropathy .

Contraindications

Precautions vitamin B3 should be taken at a peptic ulcer 12 duodenal ulcer and gastric (outside the acute stage), giperatsidnom gastritis, hypotension, liver failure, hyperuricemia gout , Glaucoma, hemorrhage. Absolute contraindication for receiving additional doses of vitamin B3 is a hypersensitivity to it, up to two years.

Side effects

With an overdose of nicotinic acid can be flushing of the upper half of the body and skin, dizziness, paresthesia . arrhythmia Strong dermal court, nausea, vomiting, dryness of the eyes and skin, diarrhea, myalgia. When applying for a long time, dizziness, headache, fatty liver, sensation of heat, hyperuricemia.

Symptoms of deficiency of vitamin B3:

• Diarrhea, irregularities in the digestive tract
• CNS: emotional instability, loss of appetite, headaches, irritability, memory loss, fatigue
• Glossitis
• Pigmentation and flaky skin when exposed to sunlight