Description overdue on 06/09/2014
- Latin name: Imunofan
- ATC code: L03AX
- Active substance: Arginine-alpha-aspartyl-lysyl-valyl tyrosyl-arginine (Arginil-alfa-aspartil-lysil-valil-tyrosil- arginine)
- Manufacturer: Bionoks (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Imunofan ampoules Each vial contains 50 micrograms imunofana . Also as part of the drug have further substance - sodium chloride . glycine . Water for Injection .
AT suppository contains 100 micrograms imunofana Additional ingredients - water . tallow . glycine . Tween 80 .
Spray It contains imunofan , Additional substances benzalkonium chloride . sodium chloride . sodium edetate . glycine . water .
Product form
The solution for injection (injections Imunofan) - a transparent liquid in the vials. The blister contains 5 or 10 ampoules, they are stacked in a cardboard box.
Candles Imunofan - A uniform consistency suppositories that are white or off-white shade. Candles may have a faint odor of a specific nature. The package contains 5 or 10 pieces.
Spray - Slightly yellowish or clear liquid. It may be not strong odor. 8 contained in vials, 5 ml.
Pharmacological action
The drug belongs to a group immunomodulatory drugs . It regulates the immune system, has a positive effect on the oxidation-antioxidant system. Imunofan positive effect on dezintokskatsionnuyu function has hepatoprotective effects.
Pharmacodynamics and pharmacokinetics
Tool takes effect after 2-3 hours, the maximum effect is four months after the start of treatment. Effects on the body occurs in three phases.
First, rapid phase It develops after 2-3 hours and lasts means about 3 days. At this time, the drug affects the detoxication function that inhibits the synthesis of arachidonic acid and inflammatory markers. If the patient struck the liver, lowers Imunofan bilirubin and liver enzymes, reduces the effects of cytolysis.
Second, middle phase effects observed three days after treatment. It lasts up to 10 days. During the middle phase is activated by exposure to phagocytosis, and killed microorganisms within the cells. As a result, it may cause an exacerbation of chronic inflammation.
The third, slow phase impact on the tenth day begins and lasts up to 4 months. At this time, under the influence of an active way Imunofan IgA, regulated by humoral and cellular immunity . Also under the influence of the drug increases the amount of specific antibodies.
There a good combination with drugs that have anti-inflammatory effects on the body (NSAIDs, steroids).
The drug also reduces the drug resistance of tumor cells and make them more susceptible to the effects of chemotherapeutic drugs.
Indications
Imunofan given to patients with the following conditions and diseases:
- immunodeficiencies in adults and children;
- in treatment chronic hepatitis B and C ;
- in treatment AIDS . HIV infection ;
- as part of a combination treatment with the oncological diseases ;
- opportunistic infections ;
- tumor Provoked HPV ;
- rheumatoid arthritis ;
- diphtheria ;
- brucellosis ;
- psoriasis ;
- bacterial endocarditis ;
- strong burns and wounds Do not heal for a long time;
- used as an adjuvant during Vaccination adults.
Contraindications
It is unacceptable to take during pregnancy means flowing with the conflict on the Rh factor. Also contraindicated is the high sensitivity to the components of the drug, the age of the child up to 2 years.
Side effects
Generally, treatment is free of side effects may occur very rarely allergic reactions.
Instructions for use (method and dosage)
Instructions on Imunofan following: injections need to be administered subcutaneously or intramuscularly, the injection is carried out once a day.
Instructions for use in the treatment of Imunofan oncological diseases the following: a means is administered once a day after one day. Before sessions of radiotherapy or chemotherapy course is conducted, including 3-5 injections. Before the operation is carried out a course of 2-3 injections.
In therapy opportunistic infections Take 1ml once a day three days. Total administered 10-15 ml.
With chronic hepatitis and brucellosis at 1ml imunofana administered once a day, with an interval of 4 days. Total administered 8-10 ml.
With Diphtheria 1ml of Imunofan taken once a day every day. Total administered 8-10 ml.
When treating bacillicarriers at 1ml imunofana administered once a day, with an interval of 4 days. Total introduced 3-5 ml.
When treating rheumatoid arthritis At 1ml imunofana taken once a day, with an interval of 4 days. Total administered 8-10 ml.
When treating burns and non-healing for a long time Wounds 1ml of Imunofan administered once a day. Total administered 7-20 ml.
As an adjuvant drug is administered 1 ml once, on the day of vaccination.
Candles Imunofan administered at a dose of 100 micrograms (1 suppositories) per day. Dosage and interval of administration for a particular disease is determined by the doctor.
Instructions for the use of a nasal spray provides a single spray when injected into the nasal passage. One dose contains 50 micrograms funds imunofana.
Instructions for animals (dogs, birds, cats, as well as for other pets) provides for subcutaneous or intramuscular administration, and also in the conjunctiva eyedrops.
Animals are assigned means for the prevention of infectious diseases, as well as for the treatment of viral and bacterial infections. For prevention, it is administered once or once every ten days in the presence of an epidemic. For treatment agent is administered in one dose a day, once a day. The treatment lasts for eight days, during which time the animal receives four doses. Detailed regimen paints a veterinarian who treats the animal.
Overdose
Data on drug overdose not.
Cooperation
In the treatment of cases imunofanom negative reaction in the interaction with other drugs has not been fixed.
Terms of sale
Sold by prescription.
Storage conditions
Means must be stored in dry and dark place, the temperature should be 2-10 ° C. Imunofan should be protected from access by children.
Shelf life
Store the drug can be 2 years. Do not use after the expiration date.
Cautions
In connection with the activation of phagocytosis may momentarily hearths worsen chronic inflammation.
Imunofan animal commonly used in veterinary practice.
Analogs
Timalin
TSikloferon
Uro-Vaks
Engistol
Imunoriks
Kipferon
Tsitovir 3
Imudon
Lavomax
Amiksin
Immunomax
Immunal
In pharmacies analogues Imunofan realized that a similar effect on the body. Known analogues of the drug: Alkimer . Immunal . Arbidol . Anaferon . Groprinosin . Wobenzym . IRS 19 . Timogen and etc.
Babies
Not applicable in the treatment of children up to 2 years.
With alcohol
The combination of alcohol and Imunofan studied little. It is not recommended to drink alcohol during treatment.
During pregnancy and lactation
During pregnancy and during breast Imunofan used with caution, as clinical data on its impact to date is not enough. Do not use if pregnancy Flowing to the conflict on the Rh factor.
Reviews imunofanom
Reviews injections Imunofan show that in most cases already after the first injection, the man sees positive changes in the condition of the body. If applied injections, sprays and candles for the children, parents also often write on the forums about the positive dynamics in the process of treatment. Responses contain information about doctors that Imunofan effective in the treatment of infectious and viral diseases. The most convenient form of the drug, according to those who write reviews are suppositories.
There are also reviews of how effective Imunofan for cats and dogs. Almost every popular forum veterinary accommodates reviews pet owners about the effectiveness of the funds for treatment and prevention.
Price Imunofan where to buy
Injections in ampoules Imunofan can be purchased at the price of 400 to 500 rubles for 5 ampoules. Cost candles Imunofan an average of 410-490 rubles per 5 pieces. Nasal Spray It will cost an average of 690-750 rubles per 1 vial.
Imunofan for cats, dogs and other animals (5 vials of 1 ml) costs an average of 260-300 rubles.
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