Description overdue on 09/15/2014
- Latin name: Tri-Regol
- ATC code: G03AB03
- Active substance: Ethinyl estradiol (Ethinylestradiol), Levonorgestrel (Levonorgestrel)
- Manufacturer: Gedeon Richter (Hungary)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Three Regola (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Reviews
- Price, where to buy
Composition
Tablets include surfactants such as ethinylestradiol and levonorgestrel .
Additional components include: talc, colloidal silicon dioxide, lactose monohydrate, corn starch, magnesium stearate.
The shell consists of sucrose, talc, titanium dioxide, macrogol 6000, red iron oxide, calcium carbonate, copovidone, colloidal silicon dioxide, povidone, carmellose sodium.
Product form
Three Regoli produced in the form of coated tablets.
Pharmacological action
Three-phase oral contraceptive.
Pharmacodynamics and pharmacokinetics
The drug belongs to a combined contraceptive drugs.
Levonorgestrel reduces production gonadotropins , Resulting in slower and ovum matures ovulation It does not occur.
Ethinylestradiol In turn, increases the viscosity of cervical mucus and reduces the passage of sperm into the uterus.
In addition, the three-regolith helps to normalize the menstrual cycle, as complementary level endogenous hormones .
The drug is well absorbed in the intestine upon oral administration. Processed in the intestine and liver and then eliminated via the kidneys and intestines.
Indications
The need for oral contraception. Treatment of disorders of the menstrual cycle.
Contraindications
Use of the drug is contraindicated in:
- over the age of 40 years;
- pregnancy and breast-feeding ;
- Heavyweight itching and idiopathic jaundice pregnant women in history;
- gallbladder disease;
- smoking at the age of 35 years;
- thromboembolism and thrombosis And predisposition thereto;
- diabetes severe;
- improper fat metabolism;
- molar pregnancy ;
- migraine ;
- otosclerosis with hearing problems;
- recent surgery;
- deficiency of the enzyme, which is needed to digest lactose milk;
- Hypersensitivity to the drug;
- liver disease;
- severe cardiovascular and cerebrovascular changes in history;
- Vaginal bleeding undetermined etiology;
- sickle cell and hemolytic anemia ;
- malignancies;
- chronic colitis ;
- Marfan syndrome ;
- phlebitis ;
- extensive injuries.
With care, this drug should be used when:
- asthma ;
- Chronic venous insufficiency the lower extremities;
- epilepsy ;
- small chorea ;
- porphyria ;
- uterine cancer ;
- depression ;
- diabetes in step compensation (in the absence of vascular complications);
- multiple sclerosis ;
- hypertension (BP up to 160/100 mm Hg. V.);
- tetany ;
- mastitis ;
- tuberculosis ;
- lack of regular menstrual cycle during adolescence.
Side effects
Adverse effects Three Regola usually following: discomfort when using contact lenses, intermenstrual bleeding, weight changes, nausea, fluid retention, changes in libido, breast sense of tension, acne . irritability . depression , Irritability, breast pain, headache . migraine , Blurred vision, gipomenoreya . amenorrhea .
These side effects are temporary and without special treatment. In rare cases can develop tumors appear lupus erythematosus . ulcerative colitis . hepatitis . Crohn's disease . jaundice .
Furthermore, increasing the number of infrequently observed triglycerides plasma glucose tolerance reduction, fatigue, increased blood sugar, chorea . otosclerosis . embolism pulmonary artery thrombophlebitis deep veins, increased blood pressure, venous thromboembolism . thrombosis , Vomiting, cholelithiasis . diarrhea . pancreatitis , Skin rashes, exudative erythema multiforme , hair loss, hives . erythema nodosum , Change vaginal secretion, chloasma The appearance of secretion from the mammary glands, fungal infections vagina.
There may be side reactions such as dizziness , Worsening epilepsy . hypertrichosis . seborrhea , A feeling of heaviness in the legs.
Instructions for use Three Regola (method and dosage)
Instructions for Three-Regoli discloses that tablets should be taken in one day at the same time. The course from the first day of menstruation and is designed for 21 days. After this has to be a break week for menstrualnopodobnoe bleeding. Then start taking the tablets again on the first package (even if the bleeding is still present). First you need to take 6 pink tablets and then - and after 5 white - 10 yellow.
The order of taking the medicine packaging specified numbers and arrows. If one pack contains 28 tablets after ingestion DY should proceed to brown (do not contain hormones), and the next course should start 28 days without interruption.
If a pill is missed (passed more than 36 hours), reliable contraceptive protection is not guaranteed. On the first and second week of the cycle in the case of the missing instructions for use Three Regola Council adopted the next day just 2 tablets.
If you missed just two pills in a row, following 2 days you need to take 2 tablets, then continue the course, as usual. When you pass on the third week of the course seven-day break is not done.
Skipping tablets does not relate to brown. They contain iron, and they are used to maintain continuity.
If the drug is prescribed for and its dosage is adjusted individually.
Overdose
At doses in excess of the patients have nausea . headache . uterine bleeding . In this case, you must consult your doctor immediately. Treatment is symptomatic, gastric lavage.
Cooperation
Caution is advised to take three-regolith in conjunction with:
- Ampicillin . Chloramphenicol . Penicillin . tetracyclines . Dihydroergotamine . Phenylbutazone . Rifampicin . Neomycin . sulfonamides Some anticonvulsants and tranquilizers, Ketoconazole - May decrease the effectiveness of contraception;
- tricyclic antidepressants . beta-blockers . Maprotiline - Possibly increasing bioavailability and toxicity of these agents;
- Bromocriptine - Can reduce the effectiveness;
- anticoagulants Derived indandiona or coumarin - May be necessary to monitor the prothrombin time, adjusting dosages;
- antidiabetic medicines for oral use, Insulin - You may need dosage adjustments;
- hepatotoxic It means - increased risk of increased hepatotoxicity.
Terms of sale
The drug is sold by prescription only.
Storage conditions
Means must be kept out of the reach of small children. The temperature must be below 25 0C.
Shelf life
Shelf life - 5 years.
Reviews of Tri-regolith
Birth control pills Tri-regolith get a variety of responses, as well as most other hormonal contraceptives. For some, they fit perfectly, and someone gets a lot of unwanted side effects. While most reviews of Tri-regolith is still positive. Some girls even "prescribe" it to themselves, without consulting with experts. And in most cases, problems with pregnancy after the cancellation rate was observed.
According to doctors about three-regolith is usually positive. They are often prescribed to patients for the normalization of the menstrual cycle. Doctors about three-regolith boil down to the fact that it is relatively harmless remedy for little money. However, the effect of oral contraceptive use is very individual. Some experts have neglected the need to analyze, so it also happens that the drug is not suitable for a number of indicators of patients who appointed him. This leads to undesirable side reactions. So appoint a three-regolith should be only after the relevant tests.
Price three-Regola where to buy
Price three-Regola compared with a number of similar funds is considered very affordable. That is why it is often recommended specialists. Price three-Regola in packaging designed for the tablet 21, an average of about 200 rubles.
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