Grammidin

Description overdue on 02/28/2013

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Antibacterial drug. The principle is based on the impact of the development of the cellular osmotic instability by increasing the permeability of the cell membrane of the bacteria to penetrate inorganic cations (due to the formation of channels in the lipid structure of cell membranes). The main substance in the preparation is Grammidin With gramicidin   - A polypeptide antibiotic. The drug is active against streptococci, staphylococci , Anaerobic infection, Neisseria gonorrhoeae, meningococcus . The medicament acts bacteriostatically, at higher concentrations there is a bactericidal effect. Grammidin available as a paste, a solution, a tablet dosage form.

Indications:

Drug Usage Grammidin recommends prescribers at pyoderma (alcohol solution). The fat and the aqueous solution is prescribed for burns, ulcers, bedsores, festering wound lesions, empyema, traumatic injuries of the joints, abrasions When carbuncles (irrigation swabs and bandages, washing). Tablets prescribed for Grammidin stomatitis , Gingivitis, acute pharyngitis, periodontitis, sore throat, tonsillitis and other infectious and inflammatory lesions of the throat and mouth. The paste is used to treat wounds and burns, as a local contraceptive. Grammidin oxybuprocaine contains anesthetic, lidocaine hydrochloride and cetylpyridinium chloride, which provide a local anesthetic and antiseptic effect, which allows you to use the drug for the treatment of diseases of the oral cavity. In combination therapy Grammidin used in barley (meybomit), infected eczema century iridocyclitis , Episcleritis, otitis externa, iritis, iridocyclitis, blepharitis, scleritis .

Contraindications:

Grammidin not prescribe intolerance gramicidin C, dermatosis   (dosage forms for external use), breastfeeding. Grammidin during pregnancy is contraindicated. Tablets Grammidin not prescribed for children until 4 years of age.

Side effect:

The drug can cause allergic reactions, phlebitis, hemolysis (for parenteral administration), contact dermatitis. Grammidin anesthetic may cause temporary loss of sensitivity of the language.

Mode of application:

Preparation of aqueous solution 2% of medicament solution diluted ordinary drinking or sterile distilled water (100-200 times). Cooking fat solution:   2% of medicament solution diluted in lanolin, fish oil, castor oil (25-30 times). Fat solution is used for irrigation of tampons, bandages and washing wounds. Preparation of an alcoholic solution: 2% of medicament solution diluted in 70% ethanol (100). Skin treated with an alcohol solution three times a day with pyoderma. Tablets Grammidin   take every 20-30 minutes to 2 tablets (3 mg) 4 times a day, course dose is 15-30 mg. As contraceptive Grammidin administered using a special syringe into the vagina in an amount of 5-6 grams. Paste Grammidin   is applied to the affected area with a thin layer, then cover the wound with a gauze bandage. Change the gauze is necessary every 2-4 days.

Special instructions:

Unacceptable administering drug solution into a vein of the risk of hemolysis and phlebitis . A freshly prepared aqueous solution can be used within three days. The price of the drug is Grammidin 120-150 rubles (depending on the pharmacy network). Responses to the drug Grammidin demonstrate high efficiency of medication in the treatment of infectious lesions.

Drug Interactions:

Grammidin able to enhance the effect of other Antimicrobial medications .