Monday, April 2, 2018

Onychomycosis

December 5, 2011

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 Onychomycosis  Onychomycosis   It is a fungal infection of nails in humans. This is one of the most common diseases from the scope of Dermatology . According to studies, the disease suffers from ten to fifteen percent of the population. Onychomycosis - a hotbed of fungal infection, which has existed for a long time. The infection is gradually spreading throughout the body, so in the course of treatment is very important to get rid of the parasite.

Occurrence of onychomycosis provoke mushrooms dermatophytes . trihofiton . yeast . molds   and others. To catch the infection may be in the process of using a variety of household items, shoes, nail accessories, with a visit to the baths, sauna, public showers. In recent years significantly increased the number of cases among children and adolescents.

Nail diseases provoke a variety of lesions: trauma, broken bones of hands and feet, poor circulation in the limbs, varicose veins, and others. Most often, the disease manifests itself in people who suffer somatic   and endocrine   illnesses, diabetes They have disruptions immune system , Taking corticosteroids or were receiving antibiotics. Except for onychomycosis nail changes occur Allergic changes   in the body, also emit harmful fungi Toxins . Onychomycosis is manifested in different ways, depending on the type of pathogen. Typically, fungal infection affects the nails on the feet, more rarely defeat nails on the hands. Sometimes the infection appears simultaneously on the nails and hands, and feet.

Forms of onychomycosis

To distinguish several forms of onychomycosis, depending on how the changes in the disease process of the nail plate. So, normotroficheskie   disease characterized by prolonged retention of the normal configuration of nails that have undergone defeat. Nail typical dull, yellowish tint near the distal edge of the plate in the corners of the nails are thicker due to subungual hyperkeratosis.


When onychomycosis hypertrophic   form thickened nail plate gradually deformed nails, they appear lateral line. Color - dirty gray. Sometimes the shape of the nail is gradually becoming a beak. When onychomycosis atrophic   form the nail plate significantly destroyed, the process of deformation, exposed nail bed. Nail Color serovyty or yellow, they are quite dull. Defeat by type oniholizisa   plate involves thinning of nails, their separation from the nail bed. Nails do not shine, the color - gray or yellow. Normal dyeing is only present in the matrix. Also, there are combined forms of the disease. Children affected nails with some features: its surface becomes rough, the nail plate is amazed at the distal edge, subungual hyperkeratosis - a rare phenomenon.

Symptoms of onychomycosis

 Onychomycosis  Symptoms of disease vary depending on the type of pathogen. So, for onychomycosis, provoked T.rubrum, characterized by multiple lesions of nails. First stop on the nail plate appear yellow spots and longitudinal stripes. The nails of the hands are also affected by horizontal stripes, but their color is more bright and dim. Onychomycosis caused by   T.interdigitale Different appearance of bright yellow spots or bands nail becomes thicker at the free edge, it is deformed plate.

Infectious disease caused by a yeast-like fungi Candida It suggests that the disease begins mostly on fingers. Rollers nails become thicker at the edges noticeable silvery scales, during palpation person feels pain, may be released a little bit of pus. As a rule, nail plates are embossed on them appear transverse grooves, the nail plate can be destroyed in the proximal region. The plate becomes thinner at the side edges, the color - yellow. When a disease that caused molds, changing the color of the nail plate, taking into account the type of agent, he may be blue, yellow, brown, green, black.

Depending on where it is localized lesion, distinguish onychomycosis lateral . distal . distal-lateral . proximal . surface . total . Lateral lesions may spread to the edge of the plate on a fairly large area of ​​the nail matrix and even deeper.

Diagnosis of onychomycosis

To establish such a diagnosis helps familiarity with the clinical manifestations of the disease. The first doctor to find fungus should by microscopic examination of the material to determine its appearance. Also, the culture of the fungus isolated by plating on nutrient media. If the study conducted by an experienced specialist, already with a microscope he could distinguish some types of fungus. Onychomycosis is necessary to differentiate with the changes that occur in the fingernails psoriasis . eczema . lichen planus .

Treatment of onychomycosis

 Onychomycosis  To the treatment of onychomycosis nail was the most effective, it is necessary to use a complex therapy. As a rule, patients received systemic antifungals, drugs for external use, the effect of which is aimed at improving blood circulation and the growth of the nail plate. Today, there are a lot of drugs - antimycotics for systemic effects. Specialist guided features of the particular case, appoint such drugs for a certain period. Before starting the treatment, be sure to make a general and biochemical blood tests.

The best known agents of this type are griseofulvin . terbinafine   ( Lamisil ) itraconazole   ( orungal ) ketoconazole   ( Nizoral ) fluconazole   ( Diflucan ). As an external means of successfully using special anti-fungal solutions in the form of varnish - Batrafen . Loceryl   and others. Before using these drugs should remove the affected area of ​​the nail plate. To determine whether it was possible to completely cure onychomycosis, is to determine whether the clinical manifestations disappeared the disease, whether fully grown nails. It is also important that the analyzes on three consecutive fungi were negative. They are carried out immediately after the treatment, and later - even twice at intervals of two months. Examination of patients after treatment of onychomycosis of the nails are held every three months during the year.

An equally important step in the treatment of the disease is considered epidemic measures. So, it is very important to disinfect visited used shoes, socks and stockings boil, follow the hygiene of nails on the hands and feet.

Prevention of onychomycosis

As preventive measures applied health education aimed at informing the public, dispensary monitoring of patients in order to detect the disease and prevent its spread among the loved ones of the patient. Prevention is important to carefully even small foot injuries, the use of funds, which help to fight the sweat, calluses, dry skin. All public places where there is high humidity should attend only rubber slippers.

Feet after washing must be sure to wipe dry socks should be changed every day. Do not walk barefoot on the beach, in the sand because mushrooms are stored for a long time. Do not use someone else's shoes. If there are dystrophic nail changes, they should be treated immediately, as the nails are significantly more likely to lend themselves to attack the disease. Thus, to prevent onychomycosis is possible only with strict adherence to the rules of hygiene.

Office workers useful tea with honey and coffee

June 21, 2013

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 Office workers useful tea with honey and coffee  Daily use tea with honey   protect against the unpleasant consequences of those who work a lot on the computer. Recently, doctors have reported that people who sit in front of the monitor every day, is to drink Three cups of tea with honey . However, this amount is to restrict.

According to experts, people who love honey   and constantly eat it, your eyes get better protection from the negative effect of computer radiation. The most useful is for the eyes linden honey   or clover . Adding a honey in tea, can be effectively removed from the human eye fatigue. Sweet Clover Honey   It helps relieve headaches, improve blood flow, stabilize arterial pressure . And here linden honey In addition to all the known beneficial properties in the treatment of colds, very effectively protects from stress . insomnia   and activates metabolism .

However, the people who work behind the monitor, helping not only medical, but also the correct mode of labor. Experts strongly recommend inseparable after each hour of work at the computer to organize a small pause . Ideally, the duration of the break must be at least 20 minutes . By doing this pause is a cup of tea with honey and a bit of a walk in the fresh air.


As for coffee, the office workers, doctors advise to use this drink in moderation. But it give up the drink definitely not worth it. Japanese scientists conducted the experiment concluded that caffeine stimulates the eye's ability to produce tears, which relieves the eye during prolonged sitting at the computer. This feature allows the coffee to protect themselves from the development of the so-called   syndrome of "dry eye" Which is very common among office workers.

But the most useful drink, researchers from the UK named tea, which is brewed from the leaves of the coffee tree . This is not a bitter beverage, like tea, and thus comprises a minimal amount of caffeine than from coffee beans. In addition, this drink contains many substances that reduce the risk of heart disease and Diabetes . Some varieties of coffee trees contain a substance mangiferin Which not only reduces the content in the body cholesterol But also protects from the harmful influence of neurons in the brain.

Sunday, April 1, 2018

Regaining your figure after childbirth

August 27, 2012

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 Regaining your figure after childbirth  Grand enthusiasm for the long-awaited birth of a small child to a young mother often slightly clouded by the fact that the restoration of the old forms will have to make many more. Because of the slim and toned figure prenatal after returning from the hospital were only distant memories. During the period of pregnancy is almost every woman accumulates a few extra kilos. And they do not always disappear on their own as they grow older kid. The fact that the restoration of the figure after giving birth involves the application of certain efforts and compliance with certain conditions.

Where do I get extra weight during pregnancy?

Excess weight for the months of carrying a baby appears not every woman. If the existing physiological norms were not exceeded, the woman gaining no more than twelve kilos for the entire period pregnancy . Consequently, during childbirth and in the first week post-partum period, all these kilos gradually leave. But if a woman gains during pregnancy for about twenty kilograms and more overweight Then get rid of it later rather difficult.

Therefore, in order to restore the figure after giving birth it was difficult, it is desirable to monitor the recruitment process more weight during the childbearing. To do this, it is strongly advised not to respond to the "compassionate" advice is constantly eating for two: in fact, during pregnancy, simply to balance the diet to include as many useful products, thus, eliminating the excess baking, confectionery fats.


It is important to remember that physical activity is relatively low expectant mother. So if every day a woman consumes more calories than it spends, inevitable rapid weight gain. Also during gestation baby woman's body suffers a dramatic change. As a result of the restructuring of all the systems there is a considerable stress   for the body, which results in the formation of body fat as a protective mechanism for the fetus. As a result, fat appear on thighs, buttocks and abdomen.

How to save a figure in the postpartum period?

 Regaining your figure after childbirth  Immediately after the direct process of birth was in the past, a woman must think not only about the major developments related to the birth of the baby, but also about their own feelings .  These days it is very important to avoid the mistakes that later not only would prevent a return to the old forms, but can lead to more weight gain .  Originally want to adjust the diet and stick to certain limits in food .  Even breast-feeding mother in any case should not overeat .  If a young mother instills the idea that quality, and most importantly - the number of its food directly determines the quality of the milk, then she should not give in to such blandishments .  After all, in fact, the production of breast milk is determined by the production of the hormone prolactin .  And his mother's production of power does not depend .  Therefore, the daily consumption of condensed milk and halva in fact does not lead to an improvement in the milk, and a subsequent increase in weight women .

Another seemingly innocent habit - constantly eat up the child of his uneaten portions of food. Poltarelki gruel for each meal your baby can have a few weeks significantly affect the buttocks, waist and hips. The same effect take on a momentum habit mom constantly taste the dishes that she prepares for the child and other family members.

However, the young mother should not feel hungry: you need to eat at least four times a day. It is best to divide the daily ration of the relatively small portions and eat them, even five or six times. To this regime entered into a habit, we can arrange life so that there with your child: first, it's fun, and secondly, it is possible to develop a useful habit to eat frequently and on a certain schedule. At the same time it should be noted that in the late evening is best to eat non-nutritive and not particularly nutritious meals.

A woman who cares about how to restore the figure after giving birth, you should build a diet so that the last meal did not take place less than four hours before bedtime. This well-known rule of slimming "Do not eat after six" in this case does not work if the young mother to go to bed at midnight or even later, in that case it dinner, of course, will be later.

No doubt, a nursing mother in any case should not rush into extremes and wear high-grade body diets   for losing weight. Now is not the time for extreme experiments: it is fraught with not only the appearance of problems lactation But the deterioration of health and mother and child. You can think about the diet not earlier than six months breast-feeding While supply method chosen should not be too ascetic.

What is in the postpartum period?

 Regaining your figure after childbirth  Even the woman, whose figure after giving birth has become more lush, should be a daily diet so as to consume at least 1,500 calories a day. However, this figure does not exceed 2000 calories. Especially young mothers, who are used to treat nutrition especially scrupulous, can help a food diary in which to record everything eaten in a day. Gradually, this habit will allow monitoring of food consumption and to adjust its quantity and quality.

Mom, who feeds the baby in breast milk, it should realize that for her there is no strictly prohibited products: just for a while to a certain food restrictions are imposed.

The food, which a woman uses every day, should contain as many vitamins. Overall food after birth in some ways similar to nutrition during pregnancy. Importantly, during lactation in some women significantly increases the appetite, it "pulls" on sweet. In this case, not to give in to the "provocation" of the body: must always be present a sense of proportion, warning overeating.

Another important rule - adequate fluid intake: Daily nursing woman must drink at least three liters of liquid in the form of not just plain water, but other beverages.

The diet should prevail boiled or steamed food. This simple method will not only ensure the normal state of health of the child, but also contribute to weight loss. After a meal of boiled used a minimum of fat.

Cook can not only vegetables, lean meat, fish and fruit. Of course, at first be limited to the use of those products that contribute to allergic reactions in the child. And here it is possible to follow the kind of diet that allows a bit to lose weight. For canned, smoked dishes and sausages have a negative impact not only on the quality of the milk, but also on the condition of the figure after childbirth.

Dairy products can not be excluded from the diet: milk, and yogurt, and cottage cheese are very useful for infants. And to such products do not gain excessive weight, and should be selected yogurt curd with a minimum fat content.

About chocolate and sweets in the first weeks is better to forget: a sweet tooth even if limited to dried fruit, honey, a few spoons of jam. But even such useful sweetness must strictly dosed as they add substantially to the overall calorie diet. No less insidious and nuts and seeds: small handful of these products, again, significantly increases the total daily calorie allowance. Therefore, in the day you can eat only a few useful, but very nutritious nuts.

But the young mother of soda do not should remember. Moreover, Unaccustomed for pregnancy and breastfeeding from soft drinks, and you can not return to the use of soda later, since in addition to dyes and sugar it contains many more harmful elements. Liquor - the prohibition of the product. Moreover, they can greatly harm the baby, she will use them more and more calories, do not carry benefits to the body.

From bread to give up completely is better to eat a small sandwich of whole grain breads than completely eliminating useful bread from the diet, eat high-calorie meat or cheese.

Another important rule - a complete ban on the use of any drugs that promote weight loss. These drugs can reduce the quality of milk and have a negative impact on the state grudnichka.

Particular attention to the organization of their own power should pay the woman, whose baby suffers from dysbiosis   or allergies . It is important to fully hypoallergenic diet Therefore, a new mother should first pay attention to how foods affect the baby. In particular, the most negative impact on the status of the young child affects cabbage, black bread and beans.

Activities to restore the figure after childbirth

 Regaining your figure after childbirth  No matter how hard the young mother to improve the diet in terms of successful weight loss, without daily exercise, this process will not be successful. Of course, my mother, breastfeeding may not be given too much time training. Yet from the first days after returning home, the woman should be given to the sport at least a few minutes a day, so that in time the question of how to maintain your figure after childbirth, did not become problematic.

Initially, as the active practice, you can use the few hours during which the mother walking with the stroller on the streets. The main condition for successful recovery figure after giving birth this way - intense and dynamic walking. Walking should be at least an hour, it is important to develop the maximum speed. No need to sit on a bench in the park, it is best to walk briskly through the streets. These daily walks to help significantly tighten the tummy and improve muscle tone. By the way, some young mothers use a special device - a pedometer that allows you to know exactly how many steps a woman made for the period of walking. The best option - to pass at least five thousand steps.

If there is such a possibility, then a month after delivery a young mother can start attending dance classes, yoga or go to the gym. But it is very important not to overdo it: doing at the gym or doing exercises, a woman should feel your body and avoid too strong surge. In the first lessons is better to try at least simulators, stretching the muscles slowly and gradually. This is not to tighten too much, so as not to disturb the joints or internal organs, which are gradually recovering from childbirth.

Souped mothers set out to restore the figure after childbirth is not always easy to find time for a hike in the gym. Therefore, exercise at home - it is a normal alternative. The complex is suitable exercises can choose according to their own wishes and feelings. Many women prefer to using videotrenirovki specially designed for postpartum period   This type of training is suitable for almost any young mother who could carve out twenty minutes for the sport during the day .  Initially, however, should not deal with every day can begin with two workouts per week and gradually increase the number of sessions to four .  If the free time at the newly-made mother is not enough even for such uncomplicated workout, it washes well in free minutes just to do a few exercises .  For example, in the morning five minutes fashionable to spend on the slopes of the body to the side .  During the day, until the baby is asleep after eating, slimming mom could make a number of approaches, by doing two or three exercises for the abdominals, as well as do well-known exercise "bicycle", which is well strengthens the abdominal muscles .  Evening exercise may be 15-20 sit-ups and a few different exercises with dumbbells .  These simple exercises for a month already positive figures displayed on condition .

A woman should objectively assess the state of their own figures and try to work it over the problem areas. Most young mothers are not happy kind of saggy tummy. This can be corrected using the same exercises for the abdominals, aerobics, swimming. If you are not satisfied with the lower part of the body as a whole, just two months after the birth a woman can do daily jogging. Initially, the optimum would be a ten-minute jog, you can later gradually bid up for several minutes, eventually bringing the run up to an hour. To effectively get rid of excess weight in the abdomen belly dance classes are recommended, as well as daily exercises with a hoop. It is important to choose a heavy hoop to hold the waist which will have to make some effort.

Before you start training, a woman can do abdominal massage with a special scrub. It can be purchased at a drugstore or cosmetic specialized departments or to use as a scrub coffee grounds. Sometimes you can create and sort of a sauna effect on the employment period. To do this, the stomach is to massage with anti-cellulite agent, and then wrap the stomach with cling film and put on a bandage on top. After a workout, you need to remove the film and take a shower.

But the main thing - to understand that any physical activity, whether it's a quick walk with the baby in a backpack, or slow swimming in the pool, be sure to have a positive effect on the figure of a young mother. respectively, and the mood in this sluchpae will be as positive.

What you need to remember my mother losing weight?

 Regaining your figure after childbirth  First of all, you should not rely on the fact that the process of weight loss will be particularly rapid. Even those women who immediately after his return from the hospital seriously thinking about how to restore the figure after giving birth and attach to this maximum efforts do not always get results quickly. The best and safest option for health weight loss after childbirth - the loss of no more than 500 grams of weight in a week.

But if a woman eats efficiently and thus lead an active life, and the extra weight still remain, it is advisable to visit an endocrinologist. It may be necessary to check the condition of the thyroid gland and to assess the hormonal balance.

However, it is believed that most women need to about the same nine months to fully restore the figure after childbirth. Therefore, even while respecting the basic rules described above, should be set to a relatively long period of recovery, as the body recovers and doberemennuyu parallel operation of other systems. Consequently, on extreme methods of weight loss during this period it is better to forget.

Another point that is important for a woman who breast-feeds the baby, the awareness of the fact that lactation only promotes faster recovery figures. After the accumulation of fat in the period of pregnancy is precisely for later use it during the period of breast-feeding. Therefore, giving these stocks, the body naturally returns to normal.

During the postpartum recovery figure must always pay attention to the gait. During gestation the baby's center of gravity is shifting, as the stomach is pushed forward, and the back leans back. After birth, this habit must be eradicated as soon as possible. This will contribute to more intense retraction of the abdomen.

Immediately after giving birth to a stomach muscle relaxation can be maintained using a special post-natal bandage. It will help prevent stretch muscles and skin at first. However, wearing the bandage is not recommended: the muscles have gradually involved in a natural way.

Periodically, it is recommended to do self-massage of problem areas by rubbing them with natural oils or special funds for anti-cellulite massage . Problem areas need to knead, rub, exercise movements, creating the effect of vibration. The main thing - do all this on a regular basis, and then a set of all the described measures will help to quickly return to the old form.

Developed a rapid test to detect signs of autism in children

May 1, 2011

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 Developed a rapid test to detect signs of autism in children    Scientists of the University of California San Diego developed test for early diagnosis of autism in children. Results of the study under the direction of Karen Pierce (Karen Pierce) been published in the American Journal «The Journal of Pediatrics».

The study involved more than 10,000 children under the age of one year. Unique technique built on questions asked by the parents of the baby. Parents are asked to complete a short questionnaire, which contained questions about the perception of words, gestures, sounds, visual communication and other forms of communication exhibited by children in this age.

During the study, 184 children were identified deviations from the norm. The children were sent to a local specialized medical center for examination, where over the next two years were under the supervision of doctors.

As a result of observation of the little patients specialists confirmed the diagnosis "Autism"   in 133 of the 184 children. Thus, the researchers evaluated the diagnostic value of the technique, Karen Pierce of 75%. Noteworthy is the fact that filling out the questionnaire parents spent less than five minutes.

Previously, scientists from Columbia University (NY) found dependence between the risk of autism in the younger child in a pair of siblings and the difference in their ages. Scientists have examined over 600 thousand pairs of children.

According to the study, the risk of autism in the younger child in a pair with a difference between the dates of birth of at least one year is three times higher than among pairs of brothers and sisters, born with a difference of more than three years. The reason for this, according to scientists, could serve as a lack of nutrients in the mother's body during pregnancy.

Ftorokort

Description overdue on 09/28/2014

  • Latin name: Ftorocort
  • ATC code: D07AB09
  • Active substance: Triamcinolone (Triamcinolone)
  • Manufacturer: JSC "Gedeon Richter", Hungary
Photos of the drug
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Contraindications
  • Side effects
  • Ointment ftorokort, instructions for use (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Cautions
  • Analogs
  • Babies
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

 Ftorokort

Composition

1 gram ointment is:

  • 1 mg - Triamcinolone acetonide   - Active substance.

Auxiliary ingredients:

  • 0, 025 g - stearic acid;
  • 0, 002 g -   methyl parahydroxybenzoate;
  • 0, 035 g - polysorbate 60;
  • 0, 18 g - 85% glycerol;
  • 0, 12 g - liquid paraffin;
  • 0, 06 g - cetyl alcohol;
  • 0, 577 g - purified water.

Product form

Ointment for external use 0 15 g of 1% in a tube.

The package contains one tube of ointment.

Pharmacological action

Antipruritic, antiexudative, anti-inflammatory, anti-allergic.

Pharmacodynamics and pharmacokinetics

Ointment ftorokort belongs to the group glucocorticosteroids (PSC)   and is used for external application. It has local anti-allergic, anti-inflammatory, anti-proliferative and anti-edematous action. When applied to the skin to prevent the boundary accumulation neutrophil   thereby reducing exudation and cytokine synthesis As well as contributing to the containment macrophage migration That ultimately leads to a reduction of granulating and infiltration.

Triamcinolone   rather quickly distributed in the body tissues.

The main metabolite of the active substance is 6-β-gidroksitriamtsinolon.

In equal proportions displayed by the intestine and kidney.


T1 / 2 Triamcinolone   from the blood plasma of about - 5 hours, from body tissues - 18-36 hours.

Indications

Application ftorokort ointment is recommended for diseases of the skin sensitive to the treatment of corticosteroids:

  • atopic dermatitis;
  • chronic and acute eczema;
  • contact dermatitis;
  • psoriasis;
  • Lichen planus;
  • Leiner's disease;
  • Exfoliative erythroderma;
  • insect bites;
  • otitis externa   (without infection).

Contraindications

  • rosacea;
  • diaper rash;
  • perioral dermatitis;
  • acne vulgaris;
  • trophic ulcer leg;
  • open wounds and burns;
  • infectious diseases of the skin fungal, viral, bacterial (including lupus);
  • age up to 2 years;
  • hypersensitivity to Triamcinolone or other components of the ointment.

Side effects

Side effects when using ftorokort are rare, and are reversible.

When applying the product, especially in large quantities may expression:

  • burning sensations;
  • dry;
  • irritation;
  • itching;
  • folliculitis;
  • akneiformnoy rash;
  • hypertrichosis;
  • perioral dermatitis;
  • hypopigmentation;
  • contact or allergic dermatitis;
  • secondary infection;
  • maceration of the skin;
  • prickly heat;
  • striae;
  • skin atrophy.

Ointment ftorokort, instructions for use (method and dosage)

Ftorokort medicament in the form of ointments applied only externally.

The drug is recommended to apply a thin layer on problem (indication) areas of the skin. The frequency of application of the drug 2-3 times a day at the maximum daily dose - '15

Instructions on the use of the ointment allows ftorokort occlusive dressings . In this case, the application of 10 g of ointment is the maximum amount per day.

The duration of treatment is usually - 5-10 days. In severe cases, it may be used for up to 25 days. Maximum safe time application of the ointment is not more than 4 weeks.

Overdose

Maybe expressed systemic effects of GCS Which docked symptomatic therapy.

Cooperation

The combined use of oral and ftorokort glucocorticoids , The effect of recent increases.

Terms of sale

Prescription.

Storage conditions

At a temperature of 8 to 15 ° C.

Shelf life

24 months.

Cautions

If you suspect a display of any side effects it is necessary to stop the use ftorokort and inform your doctor.

Like other glucocorticoids   Topical drug ftorokort not applied on the wound surface as well as on the skin around the eyes.

Using occlusive dressings   or applying ointment on large surfaces possible manifestation of the systemic effects of the drug. In this case, special care is needed, especially in the treatment of pediatric patients.

If the disease is diagnosed is complicated by the addition of a secondary fungal or bacterial infection treatment ointment ftorokort should add specific antifungal or antibacterial drug.

Particular attention is paid to the use of the drug on the skin of the face.

Application ftorokort children require special care, as the diaper or skin folds can act as a occlusive dressing Thereby increasing system resorption . For the same reason, when applying the ointment in childhood, one should consider the ratio of the weight and the surface of the skin, and insufficient maturity skin.

The recommended duration of therapy in children less than 5 days (do not use occlusive dressing ). If necessary, follow-up treatment should take place under the supervision of a pediatrician.

Ftorokort hormone ointment or not?

Ointment ftorokort belongs to the group glucocorticoids   that are steroid hormones That are generated by the adrenal cortex. Given topical application in small quantities, their effect on the body is minimal.

Analogs

Match code ATC 4th level:
  •  Ftorokort  Afloderm
  •  Ftorokort  Dermoveyt
  •  Ftorokort  Lorinden
  •  Ftorokort  Lokoid

If a patient has no contraindications apply ointment ftorokort counterparts:

  • Afloderm;
  • Dermoveyt;
  • Latikor;
  • Kloveyt;
  • Lokoid;
  • Pauerkort.

Babies

The caution may be given to children from the age of 2 years.

During pregnancy (and lactation)

Ointment ftorokort in periods pregnancy   and Lactation , Appointed by a doctor and used with extreme caution.

Reviews ftorokort

Reviews ointment ftorokort say that in most cases the drug is quite effective and well tolerated without any adverse effects.

Side effects of the drug occur when used on large areas of the body or in the application of the amount of ointment that exceeds the maximum allowed. The most common adverse effects of the application include: erythema, hypertrichosis, joining secondary infections Very rare to find mention of atrophic skin changes.

Price ftorokort where to buy

Price ointment ftorokort pharmacies Russia, depending on the region, kolleblitsya from 150 to 200 rubles.

Get the best price and buy

Pyrazinamide

Description overdue on 25.05.2012

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 Pyrazinamide  TB drugs . The action is aimed at the basic substance mycobacteria located intracellularly. The active ingredient is well into the pockets of tuberculosis. The highest efficiency is marked by the action of an acid environment. Pyrazinamide is able to provide bacteriostatic and bactericidal effects. When concomitant administration of other anti-TB drugs reduced the likelihood of developing resistance. Pyrazinamide is available in tablet form.

Indications, contraindications:

Pyrazinamide is prescribed for tuberculosis. The drug is contraindicated if you are hypersensitive active ingredient. In gout, hyperuricemia and hepatic failure of pyrazinamide administered with caution.

Side effect:

Musculoskeletal system: arthralgia , Myalgia. The digestive tract:   aggravation of peptic ulcers, disorders of the hepatic system, diarrhea, nausea, "metallic" taste in the mouth, nausea, yellow atrophy of the liver, hepatomegaly , Loss of appetite, jaundice, liver tenderness. Nervous system:   depression, anxiety, headaches, confusion, hallucinations, convulsions, dizziness, sleep disturbances. Hemostatic system and organs of hematopoiesis: splenomegaly, hypercoagulation , Porphyria, vacuolation of erythrocytes, sideroblastic anemia, thrombocytopenia. Urinary system:   dizuricheskie disorders interstitial nephritis . It is also possible to develop acne , Urticaria, photosensitivity, acute gout, hyperuricemia, pyrexia, rash, increased serum iron.


Overdose:

Manifest violation of the nervous system, liver system. Therapy posindromnaya.

Mode of application:

Pyrazinamide taken after meals, inside, 1 time per day, preferably in the morning with water. The daily dosage for a 50 kg weight is at least 1, 5 grams, and weighs more than 50 kg - 2 grams. In some cases, the drug administered one time per week at a dose of 90mg / kg, or three times a week for 2, 5 grams, or twice a week for 3, 5 grams. In no more than 2 hours and 5 grams. Duration of anti-TB treatment is 3 months or more. When poor tolerability of medicines administered in 3 doses. Persons elderly daily appoint not more than 15mg / kg. Pyrazinamide can be combined with rifampicin . isoniazid . kanamycin . streptomycin , Aminoglycosides.

Special instructions:

Prolonged use of pyrazinamide requires monthly monitoring liver enzymes and levels Uric acid   in blood. In individuals with diabetes during the anti-tuberculosis therapy significantly increases the risk hypoglycemia .

Drug Interactions:

Pyrazinamide is compatible with other anti-tuberculosis drugs. Combination therapy with ethambutol   or   rifampicin   It is indicated for chronic destructive forms of the disease. In combination with rifampicin are at risk hepatotoxic effects . Increased toxicity, and reduced excretion of drugs observed while taking medications that block tubular secretion. Pyrazinamide can increase TB activity of lomefloxacin, ofloxacin.

Thursday, March 29, 2018

Orsoten

Description overdue on 04/06/2014

  • Latin name: Orsoten
  • ATC code: A08AB01
  • Active substance: Orlistat (Orlistat)
  • Manufacturer: Krka-Rus (Russia)
Photos of the drug
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Contraindications
  • Side effects
  • Instructions for use Orsotena (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Cautions
  • Analogs
  • Synonyms
  • Babies
  • Slimming
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

 Orsoten

Composition

The composition of one capsule Orsotena following: it contains 120 mg Orlistat As well as an auxiliary ingredient - microcrystalline cellulose .

Product form

Hard gelatin capsules may have a white to whitish yellow, they contain microbeads or microgranules and a mixture of a white powder. The capsules may contain agglomerates that are very easy to fall apart when they press.

The capsules are contained in a blister pack of 7 pieces in a carton box contains 3, 6 or 12 of the blisters. Also, capsules can be packaged in a blister pack to 21 pieces, cardboard packaging contains 1, 2 or 4 blisters with capsules.

Pharmacological action

Pills Orsoten suspend the process of fat absorption in the intestine. The drug is a part of the active substance Orlistat Which specifically inhibits gastric and pancreatic lipases. The emergence of covalent bonds with stomach   and pancreatic lipase   Orlistat prevents splitting of fats contained in food. When triglycerides are not cleaved from the digestive tract are not absorbed. They are excreted in the feces. As a result, the human body receives fewer calories. Therefore, the summary shows that Orsoten helps to reduce body weight. Thus there is no systemic absorption of the active ingredient.

Pharmacodynamics and pharmacokinetics

At a dose of 60 mg three times a day, the drug being blocked approximately 25% of fat absorption from food.


Already 24-48 hours after ingestion of the drug concentration of fat in the intestinal contents of the intestine increases. If the preparation is canceled, the concentration of fat in the intestine is returned to the same parameters as before his admission, after 48-72 hours.

If the agent takes an adult body mass index of more than 28 kg / m2, at a dose of 60 mg three times a day, its effectiveness is increased by combined treatment with low-calorie diet. Mainly active weight lost in the first six months of treatment.

In addition to reducing the weight of orlistat at a dose of 60 mg three times a day can reduce the content of cholesterol . In addition, people who are drug treatment, noted the decrease in the waist.

According to research, there is minimal absorption Orlistat . When using therapeutic doses of the drug in the blood plasma unmodified orlistat is present only sporadically, wherein its concentration is very low. There are also no signs of accumulation.

Orlistat binds to plasma proteins is greater than 99%. At a minimum, it is able to penetrate into the erythrocytes .

Metabolism   It noted in the walls of the small intestine, and stomach. About 97% of the material discharged through the intestines, including 83% - as persistent orlistat. Kidneys derived only about 2% of the total dose. Full elimination from the body is 3-5 days.

Indications

Orsoten   and Orsoten Plus   is shown to receive people who need to reduce body weight. Assign an adult patients who are overweight (body mass index greater than 28). The drug can be taken only under the low-calorie diet.

Contraindications

Contraindications drug following:

  • High sensitivity orlistat ;
  • chronic malabsorption syndrome   and cholestasia ;
  • childhood and adolescence.

Precautions Orsoten appointed the following diseases:

  • diabetes   the second type;
  • violation of kidney function;
  • hypothyroidism ;
  • epilepsy ;
  • change in the volume of interstitial fluid.

Side effects

With regular use of the capsules may develop some side effects. In most cases this gastrointestinal reactions associated with the pharmacological action of the drug.

  • Digestive system : The appearance of oily secretions nature of the rectum, gassing , Periodic urgency to defecate, abdominal pain, loose stools . scatacratia More frequent bowel movements.
  • Hematopoietic system : Increase in the MHO, a decrease in the concentration of prothrombin .
  • Skin : Appearance bullous rash .
  • Allergic symptoms : hives . rash . itch . bronchospasm . anaphylaxis . angioedema .
  • May exhibit minor rectal bleeding, hepatitis . diverticulitis . cholelithiasis , Elevated liver enzymes.

If you notice any adverse effects, be sure to consult your doctor so that he has determined whether to continue treatment.

Instructions for use Orsotena (method and dosage)

The drug is taken orally in a food or decision for one hour after the meal.

Instructions on Orsoten Slim   He notes that the patient must adhere to a low-calorie diet, where, based on calories contains not more than 30% fat. Food must be spread evenly over three stages. How much time should be a means of how to take Slimming Capsules correctly, as well as individual dosage should be determined by the doctor.

Typically, for adult patients assigned to receive 120 mg of orlistat three times a day, that is, during or after each food intake. If there was no food intake or food does not contain fat, the capsule can not receive.

Orsotena maximum dose a day - 3 capsules. If the drug is taken in a dose exceeding 360 mg per day, its efficacy is not increased, but greatly increases the risk of side effects.

With a decrease in body weight of less than 5% at 12 weeks of therapy Orsotenom should be discontinued.

Even before the start of the drug is recommended to follow diet   and regularly carry out f Physically exercise . Proper nutrition and sport should be practiced, and after stopping capsules.

Overdose

Information about the overdose, as well as adverse reactions, observed as a result of an overdose are not available. If there was a significant overdose Orlistat , It is necessary to consult a doctor. Medical supervision is necessary for such a patient during the day. All of the systemic effects of the active ingredient rapidly reversible.

Cooperation

If at the same time taking cyclosporine   and Orlistat , There is a decrease in the concentration of cyclosporine   in blood plasma. As a consequence, lowers its immunosuppressive activity. Concomitant treatment with these drugs.

Receiving Orlistat   and warfarin   or other oral anticoagulants leads to changes in the value MHO.

Treatment with orlistat leads to malabsorption series fat-soluble vitamins .

It should not be used at the same time Orlistat   and acarbose   in the absence of data on their interactions.

Simultaneous reception Amiodarone   orlistat with a reduced concentration of amiodarone in plasma. Apply these medicines at the same time is possible only after the recommendation of a specialist.

There was no interaction with Orsotena F enitoinom . Atorvastatin . Amitriptyline . Fluoxetine . Phentermine . Sibutramine . Digoxin . Losartan . ethanol , Oral contraceptives, but also pravastatin . biguanidami . fibrates .

Terms of sale

Sold by prescription.

Storage conditions

Store at a temperature of from 15 to 25 degrees Celsius. The drug should be protected from children.

Shelf life

Keep Orsoten can be 2 years.

Cautions

Be sure to focus on the patients that non-compliance with a low-calorie diet and the same time taking capsules likelihood of side effects increases.

If the people who are oral contraceptives   while taking Orsoten, note the appearance of diarrhea They need to use additional methods of protection, in particular barrier.

Multivitamin Orsotenom in the treatment must be taken before bedtime, as Orlistat   impaired absorption of some vitamins.

People taking hypoglycemics Must before treatment slimming capsules be sure to consult your doctor, who will adjust the dose of hypoglycemic drugs.

By reducing the weight of the person can be marked improvements in blood pressure, reduce cholesterol levels. So people taking drugs to lower blood pressure, as well as the means to prevent hypercholesterolemia, while taking Orsotena should consult with your doctor.

If the treatment with orlistat develop rectal bleeding , Be sure to consult with your doctor.

Admission Orsotena does not affect the person's ability to manage the transport or work with the precise mechanism.

Because of the minimal absorption of orlistat to adjust the dose for the elderly and for people suffering from dysfunction of the kidneys and liver, is not necessary.

Analogs

Match code ATC 4th level:
  •  Orsoten  Ksenalten
  •  Orsoten  Orlistat
  •  Orsoten  Xenical

Analogs Orsoten drug - this drug Xenical . Orlistat . Orsoten Slim . Orlimaks . Ksenalten   and others. In the selection of drugs is recommended to always consult a doctor. Guided solely by the cost of the drug should not be. In addition, some drugs have a higher cost. In particular Xenical capsules will cost an average of 900 rubles. 21 capsule, whereas the price of an analogue of Xenical - Orsoten the drug - about 650 rubles per 21 capsule.

Xenical or Orsoten - which is better?

Reviews show that this question is no single answer. The effectiveness of drugs on the body and Orsoten Xenical depends on how correct and regular intake of capsules is, whether the person is engaged in sport, whether it complies with the diet. Both drugs are used for complex treatment of obesity. Both tools include one pharmacological group have similar active substance and are inhibitors of gastrointestinal lipases. Determine what kind of drug is selected will help the doctor, considering the individual characteristics of the person and his problems.

Is it better or Orsoten Reduxine?

Reduxine   - It is a combination tool that provides enterosorbiruyuschee and anorectic effect on the body. As the reviews, Reduxine can significantly reduce appetite, while Orsoten prevents the absorption of fat. Taking into account the different effects of medicines, their choice should be made available only to the expert.

Synonyms

Xenical . Alai .

Babies

Not applicable for the treatment of children and adolescents who are under 18 years old.

Slimming

The drug used to treat obesity .

Asked the difference between Orsoten   from Orsoten Slim It should be primarily borne in mind that the active substance in both preparations is Orlistat . Only different dosage - a capsule Orsoten used 120 mg of active ingredient, and a slim Orsoten - 60 mg. Choosing a drug for weight loss, it should be taken into account for this difference.

During pregnancy and lactation

There are no clinical studies of drug action during pregnancy   and between breast-feeding . Therefore, the means is not used for treating pregnant women and lactating mothers.

Reviews

At various sites and forums are numerous reviews Orsoten slimming. Most reviews Orsoten Slim   and Orsoten Plus   demonstrate the effectiveness of the drug. Reviews lost weight often contain information on how to help a person lose weight kilograms of the drug. As a rule, it is noted that the pills 120mg allow to lose for one month 5-7 kg.

Note that the reviews about losing weight Orsotene Slim   and Orsotene   It indicates that the most effective action of the drug observed when combining it with the reception low-calorie diet. Almost every active forum for slimming holds a discussion of how safe it is slimming. Generally, it is noted that the drug provokes side effects if the person during the treatment does not reduce the usual amount of fats in the diet.

Reviews of Orsotene doctors also largely positive. They approve the drug as an analogue of Xenical, while noting that the reception means it is necessary to practice in compliance with diet and active lifestyle.

Price Orsotena where to buy

The average price Orsotena   Weight loss is 630 rubles - 650 rubles. 21 capsule. Buy in Moscow Orsoten 120 mg (42 capsules) can be the average for 940-1000 rubles. Cost Orsoten Slim   an average of 1700-1800 rubles per pack (84 capsules). Slightly cheaper means to buy internet pharmacy in the presence of stocks and discounts. How much does a pharmacy Orsoten should specify a particular point of sale.

The cost of the drug in Ukraine (21 capsule) is about 430-450 UAH. Belarus Orsoten difficult to buy. As a rule, in Minsk and in other cities of the country must be pre-ordered slimming internet pharmacies. Similarly, you can buy the drug in Kazakhstan.

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