Miconazole

Description overdue on 14-05-2012

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Antifungal agent . The mechanism of action is based on inhibition of the process of synthesizing ergosterol   cell membrane. Miconazole active against yeast fungi It acts on dermatophytes . The antimicrobial activity against gram-positive appears microflora. Miconazole no effect on the pH of the vagina, the composition of the microflora. The drug is quickly eliminates itching encountered in fungal infections. Miconazole is produced in the form of suppositories, sprays, lotions.

Indications:

Miconazole topically applied at ringworm , In onychomycosis, with secondary infection by Gram-positive bacteria. Local drug prescribed for superinfection Fungal balanitis, vulvovaginal candidiasis, Vaginal candidiasis .

Contraindications:

Miconazole is not indicated during pregnancy, intolerance of components in the pathology of the renal system, severe liver disease, children under 12 years. With diabetes , Violations of the processes of microcirculation miconazole administered with caution, after prior consultation of doctors.

Side effect:

Receiving oral forms may cause diarrhea, nausea, and allergic reactions. When applying the external form of the drug miconazole may develop skin reactions. Vaginal Cream is an allergic response. Excessive use of the cream is marked burning sensation, irritation, itching. The symptoms disappear after discontinuation of antifungal therapy.

Mode of application:

Miconazole cream is applied topically twice a day is recommended rubbing, gentle movements to handle the affected areas. Antifungal therapy is carried out until complete recovery to prevent a recurrence. Vaginal capsules, suppositories administered before bedtime deep in the vagina. After the disappearance of the fungal infection treatment was continued for two weeks. Vaginal capsules Mikonzaol administered 7 days of 200 mg at bedtime or 200 mg on the first day, the next three days - twice a day at 200 mg, three days or 400 mg daily. During treatment, carried out by specialized mycological research, the results of which assess the effectiveness of antifungal therapy. Onychomycosis treated continuously for three months.

Special instructions:

Antifungal therapy is conducted simultaneously in all sexual partners. During gestation pregnancy miconazole can be used only in the first trimester. The cream, when applied to the affected areas is not absorbed into the bloodstream, allowing it to be used during breastfeeding, pregnancy. Miconazole is unacceptable to hit in the eye. When fungal infections of the nail plate is recommended to cut them as short as possible. In case of accidental stop required careful handling drug miconazole interdigital spaces.

Drug Interactions:

Miconazole increases the impact of phenytoin, anticoagulants , Oral forms of hypoglycemic drugs.