Aspirin

Description overdue on 17.09.2011

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Aspirin   It is a combined preparation. Analgesic effect and analgesic effect is due to the action of acetylsalicylic acid . When receiving the drug at high doses exhibits anti-inflammatory action. The drug has antiplatelet activity, that is, anticipates the emergence of blood clot . Aspirin inhibits the activity of the enzyme cyclooxygenase . This enzyme is involved in the prostaglandin synthesis So as a result of their synthesis is disturbed. One of the functions of prostaglandins is responsible for the emergence of pain and swelling at sites of inflammation.

Indications and methods of use of the drug:

The drug is prescribed to patients with mild to moderate pain of various origins, including and inflammatory. Aspirin taken for toothache and headache, painful menstruation, fever, accompanied by a sharp increase in body temperature. Aspirin is effective in treating patients acute respiratory infections . Also, it is prescribed for thrombophlebitis , Retinal vascular thrombosis, coronary heart disease, as well as violations of cerebral circulation.

Ingested orally. In the treatment of pain and fevers one-time adults should take 1-2 tablets of aspirin. The total daily dose should not exceed 8 tablets. Children over the age of four one-time take on 0, 5-1 tablets a day they can take up to 4 tablets of aspirin. However, children who suffer from diseases that are accompanied by fever, aspirin is recommended to prescribe only when other drugs have no effect.

As prophylaxis and therapy of circulatory disorders in brain drug use in a daily dose of 0, 125-0, 3 g The drug for the prevention myocardial infarction   It spends an average daily dose of 0, 3-0, 325 mg. This amount of formulation is divided into three portions. Patients who have impaired liver or the kidneys, must take a lower dose of the drug or to make intervals between aspirin longer.

Contraindications and possible side effects:

The drug is not prescribed to patients who have pathological manifestation bleeding . Aspirin should not be used in parallel with the anticoagulants And when insufficient glucose 6-phosphate dehydrogenase . Do not designate the reception of this means patients with asthma, people with hypersensitivity to salicylates   or other allergens. Aspirin is contraindicated in chronic or recurrent course of illness of stomach and duodenal ulcers, disorders in the functioning of the kidneys. Aspirin during pregnancy is not indicated. Especially contraindications relating to the admission of the drug in the last trimester.

During lactation aspirin can be used with the usual dose for several days. This feeding can be continued. If too high doses of aspirin, and its reception is conducted on a regular basis, then further process of breastfeeding should be interrupted. The drug in high doses for a long time and requires medical supervision.

In case of overdose, you may experience vomiting and nausea, pain in the manifestation epigastric , Tinnitus, headache and dizziness, drop in hearing and vision. If overdose is sufficiently large, it may be incoherent thinking, drowsiness, confusion, collapse, tremor . A person can feel suffocation . It is also possible onset of dehydration and Hyperthermia . metabolic acidosis . A lethal dose of the drug for adults is considered to be more than 10 g of acetylsalicylic acid, for children - more than 3 years

As a side effect during treatment with aspirin for those who are prone to allergic diseases, it may be " Aspirin asthma ". This applies to patients with asthma, urticaria, allergic rhinitis and hay, mucosal edema, nasal polyps. Rarely hyperergic reaction, even more rarely, patients have reported problems with the gastrointestinal tract and gastrointestinal bleeding.

Specific recommendations:

Store aspirin should be according to the rules of storage products from the list B, in a place protected from moisture.