Delagil

Description overdue on 05/12/2014

• Latin name: Delagil
• ATC code: P01BA01
• Active substance: Chloroquine (Chloroquinum)
• Manufacturer: Alkaloids Chemical Company CJSC for "IT CN Polfa Rzeszow SA", Hungary / Poland

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use delagil (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Reviews
• Price, where to buy

Composition

1 tablet contains 250 milligrams delagil Chloroquine   (in the form of phosphate).

As excipients used hydrophobic colloidal silica, corn starch, polyvinyl butyral, talc, magnesium stearate, polyacrylic acid.

Product form

The drug comes in tablet form; 10 tablets in a blister, 3 blisters in a pack made of cardboard.

Pharmacological action

Is antiprotozoal agent, also has anti-inflammatory and immunosuppressive effects. It has gametotsidnoe impact (except Plasmodium falciparum ) And contributes to the death of asexual erythrocytic forms of all existing Plasmodium .

Pharmacodynamics and pharmacokinetics

The drug is rapidly and almost completely absorbed from the digestive tract. Maximum blood levels achieved after 2 to 6 hours after ingestion. Chloroquine   bound to plasma albumin at 55 percent, is spreading fast tissues and organs (lungs, spleen, kidneys, liver). It is metabolized by 25 percent and slowly excreted by the kidneys (70 percent output unchanged). May accumulate in renal failure.

Indications

This drug is indicated for:

• photodermatosis ;
• Scleroderma ;
• rheumatoid arthritis ;
• systemic lupus erythematosus   (subacute and chronic forms);
• amebic liver abscess ;
• extraenteric   amebiasis ;
• malaria   (prevention and treatment).

Contraindications

Delagil can not be taken at:

• pregnancy   and Lactation ;
• purpurinuria ;
• neutropenia ;
• psoriatic arthritis ;
• severe arrhythmias;
• suppression of bone marrow blood circulation;
• renal failure ;
• hepatic insufficiency ;
• hypersensitivity.

Side effects

Delagil has the following side effects:

• On the side senses : Prolonged use can cause ringing in the ears, blurred vision, including retinal lesions and corneal opacity.
• On the side Cardiovascular : Lowering blood pressure, myocardial damage with ECG changes.
• On the side Nervous System : seizures . psychoses , Sleep disorders, headache . dizziness .
• On the side digestive system : stomachalgia . vomiting . nausea .
• Other side effects: changing the color of hair and skin, leukopenia . myalgia .

There may also be shown allergic reactions   as photosensitivity   and dermatitis .

Instructions for use delagil (method and dosage)

According to the instructions for use delagil for treatment malaria   drug must be taken as follows: first day - once with 1 gram of the drug through 7:00 - even 0, 5 grams; the second and third day - at 0, 75 grams each day at a time.

For prevention malaria   should take on 0, 5 grams of 2 times during the first week, after one time is always at a certain day of the week.

With photodermatosis adopted by 0, 25 grams each day for a week, then - at 0, 6 grams each day.

With systemic lupus erythematosus   - Every day 0, 4 grams.

With rheumatoid arthritis   - For a week at 0, 5 grams of 2 times a day, then - 0, 5 grams each day throughout the year.

With amebiasis - For a week at 0, 5 grams three times a day, followed by 0 25 g, 3 times a day for another week, after which 0, 75 grams of 2 times a week for 2 to 6 months.

Overdose

Overdose may be manifested in the following:

• collapse ;
• convulsions ;
• visual disturbances;
• disturbance of consciousness ;
• vomiting ;
• depression of the respiratory center, or death (for two hours from the time of oppression).

Cooperation

Simultaneous treatment with corticosteroids increases the possibility of cardiomyopathy and myopathy , from cardiac glycosides   - Increases glycoside intoxication with ethanol   - hepatotoxity And with MAO inhibitors - the possibility of neurotoxicity .

Simultaneous treatment with other drugs against malaria contributes to antagonistic effect.

Simultaneous treatment with Levamisole . cytostatics . Penicillamine , Gold and drugs Phenylbutazone   It increases the risk of skin and bone marrow aplasia .

Terms of sale

This drug prescription.

Storage conditions

Store at temperatures not above 25 degrees.

Shelf life

Delagil Shelf life is 5 years.

Analogs delagil

Delagil analogues are:

• Plaquenil
• Immard

Reviews delagilom

According to the reviews of delagilom, have an average efficiency of the drug and, in most cases, adversely affect vision.

Price delagil where to buy

Price delagil averages 150 rubles.

In Ukraine, you can buy the drug for an average of 90 hryvnia.

Get the best price and buy