It is proved that fruit and vegetables do not help to lose weight

Scientists from the University of Alabama experimentally tested the effectiveness of such a good the Council is aware of nutritionists, as a recommendation to eat more fresh fruit and vegetables. As a result, the researchers concluded that, although the Council is effective as a measure of a healthy diet - those who want not just eat right and lose weight, it does not help.

Fruit and Weight Loss

  Seven clinical trials held under the supervision of Dr. Kathryn Kaiser, took part in the general of 1,200 people. Volunteers held in diet according to the recommended today consume nutritional norm 1, 5 - 2 servings of fruit and 2-3 servings of vegetables per day.
 
  Analysis of the results showed that while a diet rich in fruits and vegetables is very useful for maintaining human health, for weight reduction, it is not practically affected.
 

  However, experts emphasize, that this conclusion does not mean that for the sake of losing weight should not abandon eating fruits and vegetables. According to them, those who want to lose weight, you should there are fruits and vegetables so as to seek to reduce the calorie content total food intake.

"Our results suggest that a simple replacement part a diet of fruits and vegetables is not working, an integrated approach, which will reduce the entire volume of food consumed, "- commented on this about Dr. Kathryn Kaiser.

It is significant that scientists are not first prove virtually useless fruits and vegetables in weight loss. Several studies have demonstrated that leaning on the various fruits, people unconsciously begin to consume more calories per day. (READ MORE)

Diets

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How useful the correct posture

Our mothers were right when they taught us to stand up straight and do not slouch. Scientists have found that the correct posture is good for you - it makes the pain easier to bear.

A person with   correct posture   not only makes a good impression on others, it is still better to cope with the pain. But fans slouch have hard times, as their body is more susceptible to discomfort. That is the conclusion reached by researchers from the Universities of Toronto and Southern California.

Scientists have attracted a group of volunteers who are beginning to strengthen the hand cuff pressure and inflated them to that level until people began to complain of pain. So determined pain threshold . Then, the volunteers had to hold out for 20 seconds in three yoga poses.

It turned out that the dominant position of yoga, in which a man stands upright, not hunched over, legs spread wide, increases pain threshold As reported in the journal Journal of Experimental Social Psychology. The researchers decided to find out whether this effect is "contagious", that is, whether one person is better to endure pain, looking at correct posture   another. To this end, participants were asked to sit down and discuss with researchers the different images of nature. Pain threshold   was measured before and after the debate.

When the researchers themselves were sitting right and volunteers stooped, their pain threshold is decreased. Scientists are not sure what is the cause of such a connection. It is possible that a particular pose, in which the hands are on his knees, and back and neck straightened, increases the production of testosterone in the body. This hormone affects the growth of the pain threshold.

So we have to continue to try to watch your posture and back - all this directly affects the health and sensitivity to pain.

Treatment and prevention

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The designer grew on his face the whole alphabet

For two years, this designer from New York has experimented with facial hair, making up with her via different letters of the alphabet. Its unique experiment has attracted the attention of journalists and hundreds of thousands of ordinary people.

Grooming facial hair

Is it possible to grow on his face the whole alphabet? That is the task set before a designer from New York, Michael Allen, who just got tired of wearing the beard. And then he set himself the task of incredible - for two years to carry out cut beard and mustache   so that the resulting image correspond to each of the letters of the English alphabet.

Grooming facial hair

As soon as he achieved the appearance of some of the letters, he did a photo, and then completely shaved off his mustache and beard to grow the next letter. On average, for each maneuver it took about two weeks. Neat cut beard and mustache   He held daily, and you can only envy such an incredible endurance of men.

"In the last two years in the world is in a trend of beards, which seems to me amazing, - says Michael. - I've seen on the streets a lot of different styles - from espanolok and rough unshaven until thick, bushy beard. The idea alphabetical beard came up to me after a playful conversation with my friends. But I do it once was filled, and for me, as a designer, it is of great interest. It was necessary to be creative, because not all letters can be presented on the face by a mustache and beard, over some had to seriously consider " .

From time to time recognition of letters designer checked on his 6-year-old son who is looking at the face of the Pope, I had to understand what letter he sees before him. And if the boy did not recognize it, then Michael was trying to come up with something more meaningful. The project started in 2011 and ended at the end of last year. (READ MORE)

News cosmetology

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Biking gives 5 years of life

Scientists have found that cycling trip to work can give you an extra five years of life. But only if you hard pedaling.

Those who prefer a fast ride cyclists live on average five years longer their peers who choose other modes of transportation. The velocity cycling   much more important than distance. This conclusion was Danish researchers from Bispebjerg University Hospital in Copenhagen.

For 20 years they watched five thousand healthy people who travel regularly by bicycle. It was found that fans of fast   cycling   We lived 5, 3 years longer than fans of slow travel. Those who pedaled an average degree of tension inhabited by 2, 9 years longer. Among women, the ratio was slightly different - the fastest cyclist lived at 3, 9 years longer, and the average rate of fans 2, 2 years longer than lovers of slow driving.

The study showed that those who ride a bike less than an hour a day, had the best chance of avoiding premature death for any reason. Of course, it's not the bike or speed. Just the researchers once again proven to be beneficial exercise. Moreover, it is intense and short loads rather than slow and moderate. Until now, many scientists are arguing about what is effective for people - two or three hours walking or jogging for half an hour fast. Danish scientists clearly speak in favor of the second option.

Fitness

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Cyclists often suspected cancer

Passion for cycling can significantly spoil the nervous system of men, as the researchers found. Avid cyclists doctors wrongly suspected that they were the victims of prostate cancer.

Consultant Surgeon of the Royal Hospital in Surrey Dr Chris Eden claims that the men who adore often pedaling, increased blood levels of the protein PSA, which is a key indicator of development Prostate Cancer . This does not mean that cyclists get sick this kind of tumor, they remain perfectly healthy people. But doctors do not know about and begin to look for cancer that can lead a man to a state of high nervous stress.

In recent years, fans of cycling is becoming more. Some refuse vehicle in favor of the bicycle for economic reasons, and someone is a means of transport seems to be a great way to exercise. As a result, the number of male patients with elevated levels of the protein suspicious PSA is constantly growing. And doctors continue to frighten them.

"Unfortunately, a lot of doctors just do not know that cycling is able to significantly increase the level of PSA in the blood of a man - says Dr. Eden. - They send these patients to a completely unnecessary diagnosis. In fact, the so-called false-positive test result . All physicians should interrogate the patients about whether they are addicted to riding a bicycle, before you start to suspect prostate cancer ".

According to Dr. Eden, regular cycling and the associated elevated levels of PSA protein does not increase the risk of developing prostate cancer. And the bike can still be considered an excellent tool for sports loads.

Industry News

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Cytomegalovirus

March 2nd, 2012

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Cytomegalovirus   (another name - CMV infection ) - A disease of an infectious nature, which belongs to the family herpesvirus . The virus affects the person as in utero and in other ways. For example, cytomegalovirus can be transmitted sexually, airborne alimentary route.

According to the existing statistical studies reveal antibodies to cytomegalovirus in approximately 10-15% of adolescents. At the age of 35 years, the number of people increased to 40%.

Cytomegalovirus scientists discovered in 1956. The peculiarity of this virus is its affinity to the tissues of the salivary glands. Therefore, if the disease is localized form, it can only detect the virus in these glands. The virus is present in the human body for life. However, cytomegalovirus is not a high level of infectiousness. As a general rule, in order to catch a virus, needed prolonged and repeated contact, close contact with the carrier.

Today, there are three groups of people, control over the activity of cytomegalovirus which is a particularly important issue. It pregnant women, people who have seen recurrent herpes And patients with impaired immune response.

Reasons for cytomegalovirus

Humans can be infected with CMV in different ways .  Thus, the infection can occur through contact, through the use of infected things in the process of organ transplantation and blood transfusion from a donor previously infected with cytomegalovirus .  The disease is transmitted, in addition, through sexual contact, airborne during pregnancy and in utero during childbirth .  The virus is in the blood, saliva, breast milk, semen, secretions of the female genital organs .  But the virus, which enters the human body, can not be recognized immediately, because in this case the duration of the incubation period is about 60 days .  These days, the virus can not be shown at all, but at the expiration of the incubation period, there is an abrupt onset .  Hypothermia and subsequent decrease in immunity are factors causing cytomegalovirus .  The symptoms of the disease manifest themselves as a result of stress .

Symptoms of cytomegalovirus

SARS   often a condition which manifests cytomegalovirus. The symptoms are similar to symptoms of acute respiratory infection, manifested in the progression of the disease. At the same time the patient feels very weak, gets tired quickly, he observed headaches, runny nose, inflamed and, accordingly, increase the salivary glands, begins to separate the saliva. At the same time on the tongue and gums of the patient appears whitish coating.

In generalized form of cytomegalovirus occurs defeat a number of internal organs. For example, inflammatory processes can take place in the adrenals, spleen, liver tissue, kidney, pancreas and kidneys. The result is a frequent manifestation pneumonia That arise allegedly without cause, bronchitis Which are difficult to treat with antibiotics. Immune status tolerate changes in people with advanced CMV. The symptoms described above, supplemented by appropriate blood pattern: thus, decreases in peripheral blood platelet counts. Very often this disease affects also the intestinal wall, the eye vessels, peripheral nerves and the brain. There may be inflammation of the joints, skin rashes.

If the disease affects the organs of the urogenital system, the patient there are chronic nonspecific inflammation. In case of difficulties with establishing the viral nature of the disease it is very difficult to treat using antibiotics .

If the virus is introduced into the body, then it begins to immune reconstitution. And after the acute phase of illness is over, perhaps a manifestation of vegetative-vascular disorders and asthenia for a long time.

People with immune deficiency (people undergoing chemotherapy, HIV-infected, as well as in patients undergoing immunosuppressive therapy for organ transplantation) the presence of CMV can cause very severe manifestation of the disease. Lesions that occur in these patients, can cause death.

Diagnosis of cytomegalovirus

In the diagnosis should take into account the fact that the presence of cytomegalovirus may be detected only in the case of special studies urine, saliva, blood, semen and smear from the genitals during primary infection or disease in the period of acute infection. If a virus is found in a different time, to diagnose it is not decisive.

After getting the infection in the body it begins to produce immunoglobulins   - Antibodies to cytomegalovirus. They suspend the development of the disease, causing the symptoms. In the process of laboratory blood tests can detect such antibodies. However, SSO antibody titer does not allow to distinguish between current infections transferred from infection. After all, in the body of the virus carrier, and cytomegalovirus, and antibodies are present constantly. This antibody does not prevent infection, cytomegalovirus and fail to develop immunity. In the case of ineffective diagnosis of the patient should get tested again after a few weeks.

Treatment of cytomegalovirus

If a person is diagnosed with cytomegalovirus, treatment of the disease will be sent out to smother all forms of the disease and eliminate unpleasant symptoms. For now, doctors do not have the means to destroy bacteria cytomegalovirus   in the human body completely.

If the symptoms do not occur in patients who have been diagnosed with cytomegalovirus, treatment of the disease is not required. It's indicative of normal immunity virus carrier.

Upon detection of the virus in the blood in this case assumes therapy support and strengthen the immune system. Consequently, it is necessary to carry out an immunomodulatory and restorative treatment. Appointed as vitamin complexes.

In the treatment of cytomegalovirus in children and adults, it is important to use a comprehensive approach to the appointment of therapy. As a rule, the treatment is assigned to receive funds from the antiviral and immune effects. With the right approach to the treatment of the body's defenses are activated, and the activation of the latent form of the disease in the future is under control.

It is important to go through all the necessary inspections and promptly identify the worsening of the disease while pregnancy . Accordingly, if a pregnant woman is diagnosed CMV treatment is chosen, taking into account all the individual characteristics of its body. If a case of severe, sometimes recommend recourse to abortion. This conclusion is based on the information obtained as a result of virological research, clinical indications, ultrasonography of the placenta and fetus.

Treatment is aimed at maintaining immunity, includes procedures for strengthening and hardening of the body. So often in this case, bath treatments are recommended, but those who have some training, you can periodically swim in the icy water.

There are many herbal teas that promote the improvement of the general condition of the body. Appropriate use of herbs with choleretic effect: rose, corn stigmas, everlasting, yarrow. You can rinse your mouth with a weak solution Iodine .

Cytomegalovirus in pregnant

However, the most serious complications of the disease occur in women who are expecting a baby. Cytomegalovirus and pregnancy - is a dangerous combination, because infection with this disease sometimes even leads to premature birth. It Cytomegalovirus is one of the reasons most often manifest miscarriage.

In addition, a child patient mother may be born with low birth weight and severe lesions of the lungs, liver and central nervous system. Cytomegalovirus and pregnancy - is the risk that the baby may not survive. Thus, according to various estimates, 12-30% of these infants die. Children who survive, about 90% of the observed number of late complications: they may lose the hearing, sometimes present speech disorders, optic nerve atrophy.

Consequently, a very important step is screening for CMV infection in the planning process of birth. If the correct approach to the use of both curative and preventive measures, the negative impact of cytomegalovirus on the course of pregnancy and the probability of abnormalities in the child can be prevented.

Cytomegalovirus in children

Upon infection with cytomegalovirus children incubation period can last from 15 days to 3 months or even more. There are congenital and acquired CMV infection. Very often, cytomegalovirus in children occurs without obvious symptoms. In congenital form of the disease infected the fetus during gestation, infected by the mother. From maternal blood enters the placenta virus, whereupon it is blood and fetal tissue penetrates more salivary glands. If the fetus has been infected early in pregnancy, it may die. Otherwise, the child is born with a number of serious defects. Thus, cytomegalovirus children can cause microcephaly . Hydrocephalus And other pathologies of the brain and the subsequent development mental retardation . Perhaps the birth of children with disorders of the cardiovascular system, gastrointestinal tract, lungs, respiratory tract. Also, cytomegalovirus in children causes convulsions . paresis . paralysis .

If the child was infected in late pregnancy, the newborn is not observed pronounced defects, but the disease is expressed expressed jaundice , A child increased spleen and liver, it may result in lungs and intestines.

If there is an acute during cytomegalovirus infection, the newborn there are a number of symptoms: slackness , Poor appetite, can increase the temperature of a child is bad gaining weight is unstable chair. There are hemorrhagic rash on the skin. After some time due to poor recruitment develops anemia . malnutrition . In general, there is a very severe course of cytomegalovirus infection, and as a result often ends with the death of a child in the first month of life.

If the illness is chronic or asymptomatic, the child's condition is satisfactory.

When acquired form of the disease the child becomes infected during childbirth, or gets an infection in the first days of life in contact with a carrier of infection.

There are two types of the course of cytomegalovirus in children, in this case, either in isolation affects the salivary glands, or there is a loss of some or organ. As a child's symptoms manifest fever, and swollen lymph nodes in the neck, and elsewhere. Swollen mucous pharynx, increased tonsils, spleen and liver. The child refuses to eat, broken chair - manifest constipation   or diarrhea. Manifest lung disease, gastrointestinal tract, jaundice of the sclera, trembling limbs. Chance and sepsis But the effect of treatment with antibacterial drugs is not shown. During a long disease, the diagnosis is usually difficult to establish, because cytomegalovirus in blood and saliva are sometimes not detected.

Also, if a child has contracted CMV can manifest cytomegalovirus hepatitis . These children are born with severe hemorrhagic syndrome and a number of malformations described above. Very often, the disease ends lethally.

Prevention of cytomegalovirus

Prevention of CMV is mainly in compliance with the rules both personal and sexual hygiene. It is important to comply with due care, contact with infected people. The most carefully caution should be exercised during pregnancy: in this case should not be allowed casual sex. Another important point in the issue of the prevention of cytomegalovirus - supporting immunity. It should be physically active life, eat right, walk in the fresh clean air, take vitamins and avoid stressful situations. Children should be taught the correct way of life and health from the first years of life.

Espumizan

Description overdue on 23.03.2012

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Carminative . Active Ingredient - simethicone . The action of the drug is aimed at reducing the surface tension, thereby destroying Espumizan gas bubbles in the mucus in the digestive tract and nutrient suspension hinders the formation of gas bubbles. The released gas output by peristalsis   or absorbed by the intestinal walls. Thanks espumizanu warned interference images of overlap during rengenografii . Sonography . Simethicone prevent rupture of the film with a contrast agent, improves irrigation of the colonic mucosa contrast media. Espumizan produced as a suspension, capsule, caplet, tablet, emulsion. Espumizan Infant administered in the form of drops.

Indications:

Espumizan prescribed for syndrome Remgelda , Bloating, gas accumulation. The drug is used for enhanced gas formation in the digestive system. Simethicone is effective as a defoamer for poisoning detergent surfactants. At a gastroscopy Simethicone prescribed for the prevention of formation and obrazovaniya foam. The drug is prescribed to diagnostic examination of the digestive system.

Contraindications and side effects:

Espumizan not prescribed for obstructive diseases of the digestive tract, bowel obstruction , Intolerance simethicone. Espumizan can cause an allergic response.

Mode of application:

Espumizan designate the interior of the capsule 1-2 or 25-50 drops. Acceptable dilution in liquid, the recommended time of admission - before eating the day before sleep. Espumizan for babies: three times a day for 10-15 drops. To prepare for the examinations of the intestine: in the morning on the day of diagnosis of 50 drops on an empty stomach. Before use, shake the bottle with simethicone.

Blisters

September 19th, 2013

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Blisters   - A formation on the skin in the form outlined drive, towering above the skin. Watery blisters can have very different shapes and sizes. They usually dense to the touch.

As the blisters appear?

Water blister in different areas of the skin tend to arise suddenly, but after a certain period of time, they disappear. The size of the blisters, depending on their causes vary: they may be small, but sometimes blisters have a lot of space.

Color blisters also can be different. They may be palely, pink, have a darker pink rim. In some diseases appear red blisters . Most people said that there were blisters on the ground scratching or where previously there was burning and itching.

Why do I get blisters?

Abdominal skin can be exposed to the bites of insects, chemicals, and also due to a number of other reasons. At various diseases blisters appear on different parts of the human body.

The blisters on the hands can occur in people of any age. If the pre-going friction of a subject on the skin of palms or fingers, and then hands blistered, in this case we are talking about calloused . Small blisters appear after low-energy friction. As a rule, the fact that there were blisters on the hands, often noted by those who, after a break, working with different tools in the garden.

The blisters on the hands may be the result of burns with hot steam, exposure to the sun too long, or skin contact with hot liquid. Another frequent cause of blisters on his hands - burns. This is in direct contact with different chemicals: toxic substances for pest control, fertilizers and others. After some time, the blisters on your fingers itch than deliver discomfort man.

Sometimes small blisters between the toes appear some time after contact with chemicals. Even small blisters can deliver serious discomfort. For example, if the finger were such education, the people running much slower, and some work in general can not perform. Therefore, any contact with chemicals or substances of unknown origin should wear rubber gloves.

Sometimes blisters on the hands appear due to allergic reactions in the body. This can be either allergic to food, and the reaction provoked by intake of some drugs.

Enough is a serious problem autoimmune diseases One of the symptoms which - blisters, including on arms. At pemphigus vulgaris   Bubbles are observed not only in the mouth, but also on the hands. In autoimmune diseases, called dermatitis herpetiformis , Small blisters on the palms itch, itch. This disease is a chronic and subcutaneous blisters occur periodically throughout life.

The blisters on the palms and soles, and also appear as a result of a number of infectious diseases. It chicken pox . fungal infections . shingles . infectious diseases of the skin .

Blisters on the lips of some people appear quite often. The main reason that explains the situation when a person jumped on the lip blister - herpes . With the development of this disease blisters arranged along the border of the lips with the skin. Blisters on the upper and lower lip appeared a few days after the onset of illness. Inside the bubbles contained a clear liquid. After some time, a few blisters merge into one, then the discomfort in humans is much stronger. Gradually, the liquid in the bubble inside the mouth cloudy, bubbles burst. Approximately ten days after emergence, they dry up and disappear. Bubbles herpes appear periodically during the exacerbation of the disease.

Blisters on the inside of the lips sometimes appear at a stomatitis. It can be as white blisters and bubbles from the transparent liquid inside.

The red blisters on the tongue also occur in people who are infected with the herpes virus. They are usually painful, so the patient constantly feels discomfort. Sometimes blisters appear on the sides of the tongue under the tongue. They look like small bumps. The reason for this phenomenon - ascomycetes Who constantly have in your mouth. But their activity can increase as a result of impaired immunity.

The blisters on the tongue, as well as in other areas it may appear as a result of infectious diseases. With a strong cold blisters are present in the throat and tongue. In this language there is a white film. Furthermore, bubbles may appear in the language in pharyngitis And certain skin diseases. A blood blister on language often appears as a result of injury.

Causes of blisters in the mouth, and sometimes associated with gerpepticheskim stomatitis . In this disease, blisters occur in the oral cavity, in particular on the oral mucosa. Causes of blisters - inflammation of the mucous membranes of the mouth, provoked by the herpes virus. In this case, should not self-medicate. If you appear in the mouth or tongue blisters, you should contact your doctor to establish the correct diagnosis. Moreover, it is not necessary to delay the consultation, if the mouth jumped a blister, which delivers a strong discomfort.

White blisters in the throat lie at tonsillitis . It is clearly visible bubbles that are localized in the tonsils. But sometimes, especially when heavy during sore throat, blisters appear on the back of the throat. At the same time the person feels a sharp pain in his throat, he strongly fever, blisters on the throat appear in the background of a strong reddening, marked increase in the lymph nodes. The flow of a sore throat is always difficult, especially in children. Tonsillitis usually develops as a result of strong hypothermia or low immunity.

Blisters on the feet, usually associated with wearing very tight shoes and strong tensions in some places. Sometimes small blisters on her feet itch, discomfort deliver slack, but they disappear quickly. To avoid blisters appeared larger and aggravated the problem, it is important to choose good shoes and be sure to keep clean the skin around the blister appeared. Water blisters on the toes, on the feet can not be pierced. If blisters on the hands and feet have been damaged by accident, and in their place are formed red wound, you should immediately apply a bandage. Sometimes blisters between the toes and appear due to fungal diseases. In this case it is necessary to visit a doctor and carry out anti-fungal medication.

If the body appeared itchy blisters and white, then we can talk about hives . Bubbles hives sometimes pinkish color, their size may also vary. When hives in the field of occurrence of blisters person feels very itchy.

Blisters appear as a result of burns, if there was contact with hot steam, surface, liquid, fire .  Treatment blister burns initially involves first aid - to cool burned area with cold water .  The blisters can not be pierced after the burn, because then the risk of infection .  If the blister is still burst burst or if it is necessary to protect the burn from dust, foreign objects and to prevent abrupt drying up of this place .  How to treat burns, the envy of the extent of damage .  In first-degree burns are usually only appears redness that disappeared after a few days .  Blister appears when a second degree burn .  In this case, the victim needed medical care .  So if there was a burn with boiling water, or the person suffered severe sunburn, you should always consult a doctor .  Blisters appear after getting burned a few hours .  Even with a small area of ​​skin lesions (for example, if there was a burn finger) on the site of the lesion may remain scars .

How to get rid of blisters?

Before taking any measures aimed at the treatment of blisters, be sure to determine what the cause of the blisters occurred in the case.

Watery blisters on the body, usually after some time pass without the use of special measures. The main thing - do not violate their integrity. If there were blisters on the body due to friction burns or slack, in most cases they disappear on their own and do not require special treatment. Gradually, under the skin of the affected area there is a new skin. Small blisters can not be pierced, as this would provoke irritation, pain and increase the risk of infection. If a blister filled with liquid, it protects the damaged skin from infection and promotes more intensive healing.

If there were red blisters on the body, you must initially be examined and eliminate infectious diseases. Sometimes a rash on the body may indicate varicella . Rubella . Measles and others. In this case, the patient may note that his entire body was covered with a rash. Blisters cause discomfort, itching body, symptoms of general malaise. Should see a doctor immediately to find out the correct diagnosis.

Treatment of blisters that appear on the tongue, is carried out to reduce the discomfort of the patient, as such bubbles are very painful. If the cause is herpes, appointed external preparations. To reduce discomfort and pain can be periodically rinse the mouth with a decoction of herbs - chamomile, succession.

Gargle with a decoction of herbs, as well as other useful solutions and tonsillitis, in which there are white blisters in the throat. To this end also use soda solution with addition of iodine. However rinsing will effect only if practice them every two hours throughout the day. In severe angina patients received welcome antibiotics .

If a person were blisters on the face due to herpes, the treatment is performed using special preparations - acyclovir and others. Children are encouraged to lubricate the affected places oxolinic ointment .

When the blisters from burns initially to cool burned area in cold water, and later hold it antiseptic. Then, if necessary, be appointed ointments, gels and other outdoor products, accelerating the healing process. Blisters arising after the burn, do not need to pierce.

Blisters on the lips sex and male sex organs may indicate the development of Genital herpes . This problem requires specialist-consultation venereologist.

You can not self-treat blisters to people who are sick diabetes   and diseases of the circulatory system.

If blisters appear due to insect bites, the bite should be lubricated by external means - corticosteroids (eg, hydrocortisone ). Such blisters on the skin itch, so it is important to reduce the itch that people do not comb bite. If immediately after the bite on the skin appeared watery blisters, can be put on this place a cold compress, rub the bite with a cotton swab, pre-impregnated with a solution of soda. To prevent severe allergic reactions, antihistamines practice techniques. Severe pain at the bite relieve analgesics. Even if heavily scratched skin, touch the bite is not necessary. As a rule, with the right care watery blisters on the skin disappear after a few days.

When as a result of friction blisters on the feet or on the skin of the hands should seal the plaster the affected area, the skin is not damaged further. If after wearing shoes on their feet appear red abrasions, and thus the person feels uncomfortable, you should at least for some time to change shoes to avoid blisters. But if a large blister on his leg burst, and from the constant bleeding, self-in this case can not be engaged. To the doctor should always be treated as if infected wounds under the blister.

Fast Fanigan

Description overdue on 08/18/2014

• Latin name: Fanigan Fast
• ATC code: M02AA
• Active substance: Sodium Diclofenac (Diclofenac)
• Manufacturer: Kusum Healthcare Pvt. Ltd. (India)

Photos of the drug

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions on Fanigan Fast gel
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

Active ingredients: diethylamine diclofenac   - 1 g menthol 50 mg linseed oil   - 30 mg, methyl salicylate   - 100 mg;

Excipients: carbomer 940, propylene glycol, disodium edetate, benzyl alcohol, polysorbate 80, solution ammonia Water.

Product form

The drug is a homogeneous white gel with a characteristic odor. 30, or 100 grams of the gel in a tube, a tube in such a carton.

Pharmacological action

When using a local cause anti-inflammatory, analgesic   and anti-edema effect. Reduces inflammation and pain in the joints, reduces morning stiffness and swelling of the joints, helps to increase in motor activity in the joints.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Diclofenac   It is a nonsteroidal anti-inflammatory agent. Blocks cyclooxygenase , Inhibits the synthesis of prostaglandins   - Endogenous mediators of inflammation, pain and temperature. In this way diclofenac It reduces pain and inflammation.

Menthol   annoying cold receptors. As a result, locally it reduces the permeability of capillaries and there comes a feeling of coolness. Menthol   also has a local moderate analgesic effect.

Derivative salicylic acid methyl salicylate   It has a local irritant effect. As a result of released substance P   of nerve cells. This weakens pain. Methyl salicylate also inhibits the biosynthesis prostaglandins Which weakens the swelling, and tissue infiltration.

Butter   received flax seed   produces anti-inflammatory   and antioxidant   action at the application activates the blood circulation.

Pharmacokinetics

Fanigan Fast gel begins to act after 2-4 minutes after application to the skin. And after half an hour the action reaches its maximum strength. The disappearance of the main clinical symptoms usually occurs within the first few days after initiating therapy Fanigan Fast gel.

The local application of the drug is absorbed about 5% of the dose used, its systemic exposure is minimal.

Indications

• Local therapy fibrositis . myositis , Sprains and tendon injuries of the musculoskeletal system.
• Pain in the joints and muscles during exercise, inflammatory diseases of the joints and spine, rheumatic diseases ( arthritis . bursitis . tendinitis ).

Contraindications

• Allergies   to diclofenac , Any other components of the medicament, aspirin   or otherwise NSAIDs .
• Nettle-rash , Seizures asthma   or acute rhinitis Caused by the intake Aspirin   or other NSAIDs .
• Damage to the skin or wound in the use of the drug.

Side effects

Fast Fanigan ointment is well tolerated by patients. However, sometimes the application may cause irritation, redness of the skin, itching.

In rare cases, reactions develop hypersensitivity Including hives . eczema , Pustular rash, swelling, dermatitis . angioedema . It is also possible the emergence of bronchospasm and dyspnoea.

Instructions on Fanigan Fast gel

Instructions for use ointments Fanigan Fast recommends that adults and children of 12 years applied to the skin of 3-4 g of gel and rub up to three times a day. The average daily dose - about 10 grams of gel is equivalent to 100 mg diclofenac sodium . The drug should be applied to intact skin, avoid contact with mucous membranes and eyes. The duration of therapy is determined by the attending physician depending on the disease and the clinical effectiveness of the treatment.

The gel is not recommended for more than two weeks with injuries and rheumatism   or more than three weeks at arthritis .

Elderly patients are in need of correcting the dose and dosing frequency.

Overdose

The appearance of symptoms of overdose unlikely, since absorption diclofenac   into the systemic circulation at small local application.

Symptomatic therapy is the development of complications, such as pressure- . seizures , Renal failure, respiratory depression, dyspepsia .

Cooperation

With long-term use of the gel Fanigan Fast high-dose should take into account that diclofenac   enhances the effects of corticosteroids, anticoagulants , Preparations lithium   and enhances the effects of thiazide diuretics   and furosemide .

When sharing multiple local NSAIDs   likely to occur hives . hyperemia , Peeling.

Terms of sale

You can buy without a prescription.

Storage conditions

Keep away from children. Do not freeze. Store in original container at a temperature no higher than 25 degrees.

Shelf life

Three years.

Cautions

Caution should be used in conjunction with oral medication NSAIDs   and ulcer   12 duodenal ulcer   or stomach , Renal failure or liver disease, polyposis   nasal mucosa.

Analogs

Match code ATC 4th level:

• Diklovit
• Naklofen
• Artrozilen
• Olfen
• Feloran
• Fastum gel
• Nise
• Diclofenac
• Dolgit
• Dolar
• Flamidez
• Ketonal
• Ketorol
• Indomethacin

Analogs Fanigan Fast gel: Phenylbutazone, Voltaren, Diklak, Dikloran, Diclofenac, long, Nise, Fastum   and others.

Babies

Prohibited use of funds for children under 12 years.

During pregnancy (and lactation)

It is forbidden to use the drug during the III trimester of pregnancy.

For I and II trimesters Fanigan Fast gel is allowed to be used only when absolutely necessary for a short period of time.

When breastfeeding should also avoid the use of this tool.

Reviews

Fanigan Fast gel produces an effect similar to any ointments on the basis of NSAIDs So feedback and preparation of standard and do not differ from reviews of his peers.

Price, where to buy

Price dosage of 30 grams of the drug in Ukraine is close to 26 hryvnia in Russia - approximately 159 rubles.

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Omacor

Description overdue on 23.08.2011

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Omacor is lipid-lowering drugs Containing essential fatty acids such as docosahexaenoic   and Eicosapentaenoic acid . This drug reduces the content triglycerides   and it has an active effect on hemostasis Because it reduces the synthesis thromboxane   and increases the blood clotting. Furthermore, it retards the drug triglyceride synthesis in the liver, which in turn causes an increase in fatty acid oxidation.

According to the results of observations in patients who were taking Omacor over one gram per day, decreased mortality and incidence heart attack   and stroke .

Indications:

Patients discharged Omacor in the prevention of heart attack along with ACE inhibitors, antiagregatnymi means   and platens . It is also recommended for mixed and endogenous hyperlipoproteinemia .

Dosage:

Omacor be taken inside, during the meal. For the prevention of myocardial dosage is one capsule per day, for the treatment of hypertriglyceridemia   - twice as much. In the absence of effective dose can be increased, but no more than up to four capsules per day. The duration of therapy is determined individually.

Side effects:

During the use of the drug may occur, these side effects: nausea, dyspepsia , Gastritis, gastrointestinal disorders, abdominal pain, gastroenteritis , Vomiting, constipation . flatulence ; headache, dysgeusia, dizziness; hypersensitivity reactions; dry nose; decrease in blood pressure; hyperglycemia; itchy rash, acne, rash. In very rare cases, after prolonged use of Omacor experienced higher levels LDH   and CK , An increase of ALT, AST, weight gain; acne   and eczema .

Contraindications:

Omacor is contraindicated in case of hypersensitivity, lactation, pregnancy, exogenous hypertriglyceridemia. With care it is necessary to designate people with impaired liver function, during surgery, serious injury to persons younger than 18 and older than 70 years.

Special instructions:

For patients who have increased the dosage must constantly monitor the doctor. It should be noted that people with risk hemorrhage   may increase bleeding. At the same time taking Omacor and fibrates is not recommended. May increase in liver transaminases.

In pediatrics the drug should be avoided. Omacor is hardly affects the ability to control any drive mechanisms and vehicles.

Overdose:

In overdose Omacor may appear or increase the side effects. In order to carry out their treatment therapy, in accordance with emerging symptoms.

Drug Interactions:

The risk of prolonging bleeding occurs when you use a Omacor oral anticoagulants . This medication can be administered together with warfarin As complications. Although, if you combine the reception of these two drugs, and then stop the course of Omacor, the prothrombin time should be monitored.

Supply of pharmacies:

Omacor released strictly on doctor's prescription.

Terms and conditions of storage:

This drug should be stored in a place where not penetrate direct sunlight, which can not penetrate the children, and where the temperature does not exceed twenty-five degrees Celsius. Omacor is kept for three years; It is strictly prohibited to use the medication after the expiration date.

Neurobeks

Description overdue on 11/11/2014

• Latin name: Neurobex
• ATC code: A11DB
• Active substance: Thiamine or Vitamin B1 nitrate + Pyridoxine hydrochloride or vitamin B6 + B12 is cyanocobalamin or vitamin (Thiamine + + Ryridoxine Syanocobalamin)
• Manufacturer: Balkanfarma AT-Dupnitsa, Bulgaria

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions on Neurobeks (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• With alcohol
• Reviews
• Price, where to buy

Composition

One pellet includes in its membership the active substance: thiamine nitrate   - 15 mg,   pyridoxine hydrochloride   - 10 mg, cyanocobalamin   - 0, 02 mg.

Additional ingredients: lactose monohydrate, povidone, wheat starch, magnesium stearate, talc, colloidal silicon dioxide.

The shell composition includes sugar, cellulose acetate phthalate, gum arabic, talc, macrogol 400, macrogol 6000, glycerol and dye E124.

Product form

Produced product as pink round shaped tablets coated. The package includes 10 or 30 pieces.

Pharmacological action

Neurobeks - it   combined preparation , Which included B vitamins .

Pharmacodynamics and pharmacokinetics

The action of vitamin preparations due to its constituent substances.

Thiamine Entering the body is subjected to phosphorylation, resulting in a kokarboksilaza   - Coenzyme of many enzyme reactions. This material is necessary for the performance of carbohydrate, protein and fat metabolism, carrying nerve impulses in the synapses. At deficiency Vitamin B1   It accumulates in the body dairy   and pyroracemic acid That often leads to polyneuritis, beriberi, Korsakoff's syndrome, Wernicke's encephalopathy, polyneuropathy, malfunction of the heart, damage to the gastrointestinal tract.

Pyridoxine   essential for the full activity of the nervous system. The phosphorylated form of the substance - is coenzyme metabolism of amino acids and enzymes functioning in the nerve tissues. Also noted is involved in the biosynthesis of pyridoxine neurotransmitters : norepinephrine, epinephrine, dopamine, serotonin, GABA and histamine . The reason for the deficit of B6   may not be enough food, the problem of absorption in the gastrointestinal tract, reception of medicines - antagonists When radiation treatment. Deficiency symptoms appear seborrheic lesions around the nose and eyes,   glossitis, stomatitis, peripheral neuritis, convulsive states and anemia .

Cyanocobalamine   It participates in the process of hematopoiesis and provides a full maturation of red blood cells. Also, using B12   carried out important biochemical reactions that provide the vital activity of the human body - the transfer of methyl groups, the synthesis of proteins and nucleic acids, the exchange of amino acids, carbohydrates and lipids. This material affects the function of the nervous system: the production of RNA, DNA, and so on myelin. Coenzyme form cyanocobalamin - adenosylcobalamin and   methylcobalamin   required for growth and replication of cells. At deficiency vitamin B12 emergent adverse symptoms affecting the nervous system and hematopoiesis.

Erythropoiesis   converted to megaloblastic and severe cases cause the development of pancytopenia. Disorders of the nervous system can occur irreversible damage - demyelination, loss of neurons in the spinal cord and the cerebral cortex, followed by unstable gait, paresthesia in the extremities, a violation of basic reflexes. At a later stage there may be mental disorders, hallucinations, mood swings, memory loss and vision, the development of psychosis.

Absorption thiamine   and pyridoxine   comes from the upper intestine is uniformly distributed in the body. The degree of absorption depends on the dosage of the drug.

Cyanocobalamine   mainly absorbed in the upper intestine and stomach. The fabric material is delivered to the transport protein transcobalamin II. B vitamins that are part of this drug is metabolized in the liver.

Excretion from the body thiamine   and pyridoxine   carried out by the kidneys, high dose - through the intestines. Withdrawal cyanocobalamin   It takes place in the bile, a small part of the kidney.

Indications

Neurobeks often prescribed in treatment when:

• asthenic syndrome, chronic fatigue syndrome, vegetative-vascular dystonia, encephalopathy, osteochondrosis, neuritis, polyneuritis, radiculitis, sciatica, neuralgia , Spastic states of central origin, myasthenia Traumatic lesions of CNS, and so forth;
• chronic circulatory failure,   myocarditis, myocardial dystrophy Cardiovascular diseases;
• diabetes   and its complications, obesity , Thyroid disease, disorders of metabolism of hormones hypothalamic-pituitary system;
• circulatory disorders of the retina, myopia, astigmatism, amblyopia,   glaucoma, macular degeneration,   optic neuritis, diabetic retinopathy, cataract;
• neurodermatitis, eczema, acne, dermatitis   various origins , Herpes zoster;
• neuritis auditory nerve sensorineural hearing loss, labirintopatii;
• menstrual irregularities, mastitis, conservative treatment uterine fibroids, salpinogooforite, endometrial hormonal contraception;
• diseases of young children - diathesis, malnutrition, paratrofii The lag in the development of the child, in the period of intensive growth, recovery after infectious diseases, syndrome of school exclusion, cerebral palsy;
• antibiotic therapy , Chronic diseases, alcoholism In old age and in the diet.

Contraindications

Do not take this medicine if:

• acute thromboembolism;
• erythrose;
• eritremii;
• high sensitivity to its components.

Side effects

When treating Neurobeksom may develop allergic manifestations, such as: itching, hives.

Also available: tachycardia, nausea.

Instructions on Neurobeks (method and dosage)

This drug is used to treat adults and children from 2 years.

According to the instructions for use Neurobeksa, adult recommended daily intake of 2-3 tablets 3-4 times.

For children older than 10 years, the daily dosage is - one tablet 3 times, 5-10 years - one tablet 2 times a day, 2-5 years - one tablet once per day.

Treatment is carried out for a long time, on average - 2-3 months.

It is recommended to take the tablets at the same time or after a meal, as a whole, washed down with plenty of liquid.

Overdose

In cases of overdose in patients developing nervous excitement, pain in the heart, tachycardia.

This is carried out following treatment: gastric lavage, Activated carbon   and other symptomatic therapy. It must be remembered that the antidote is pyridoxine isoniazid.

Cooperation

Concomitant use with oral contraceptives Neurobeksa drugs can reduce the content vitamin B6   in the body. Pyridoxine is able to provide a variety of effects on the metabolism of various drugs, as well as lowering the anti-Parkinsonian effect levodopa.

Antagonists vitamin B6   relate thiosemicarbazone   and isoniazid . The positive effect of pyridoxine on the condition of patients in the sideroblastic anemia that cause these anti-TB drugs. Also deficit vitamin B6   may occur during long-term treatment penicillamine.

Antagonists pyridoxine   represented by the compounds - cycloserine   and   hydralazine . The combination vitamin B6   and these antagonists are capable of lowering the neurological effects of these drugs.

During the reception Neurobeksa to refrain from the use of other multivitamin complexes, including in its composition B vitamins

Terms of sale

The drug is sold without a prescription.

Storage conditions

For storage Neurobeksa suitable dark, dry place inaccessible to children, with temperatures up to 25 ° C.

Shelf life

3 years.

Analogs

Match code ATC 4th level:

• Neurobeks Forte
• Milgamma
• Milgamma Compositum
• Neyrorubin

Analogs of this drug:   Neurobeks Neo Neurobeks Forte Milgamma, Aevitum, Citoflavin, Neyrorubin   and others.

Alcohol and Neurobeks

The combined use of alcohol and drugs Neurobeksa may reduce the absorption of thiamine in the body.

Reviews Neurobekse

As the reviews of Neurobekse, the most popular vitamin preparation is enjoyed by women. It shall take all who wish to improve the condition of the body - appearance, hair, nails and so on. However, many note the high efficiency of the funds, provided a full course of reception in addition to preparations of zinc, calcium, and vitamins A and C.

Women often say that under treatment at least twice a year. In addition, the common lot of reviews on the use of Neurobeksa after undergoing the complicated diseases. In most cases, therapy was highly effective.

Also at the forum found many discussions on the topic:

What is different from Neurobeks Neurobeks Forte?

As experts, the main difference of these drugs is that Neurobeks Forte   Admission is contraindicated during pregnancy   and patients under 14 years. The main reason for this is in the composition, the dosage of components and features of the impact on the human body.

Price Neurobeksa where to buy

Price Neurobeks in Moscow varies between 300-350 rubles. The cost of this drug in Ukraine is 107-120 UAH.

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Zoladex

Description overdue on 09/22/2014

• Latin name: Zoladex
• ATC code: L02AE03
• Active substance: Goserelin Acetate (Goserelin Acetate)
• Manufacturer: AstraZeneca (UK)

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Zoladex (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• With alcohol
• Reviews
• Price, where to buy

Composition

Zoladex (Zoladex) contains, as active substance goserelin acetate And the following additional components: glycolic copolymer   and lactic acid , and low molecular weight   and high molecular weight glycolic   and lactic acid .

Product form

Produced Zoladex 3, 6 and 10 mg, 8 mg capsules for subcutaneous administration.

Pharmacological action

The anti-tumor drug.

Pharmacodynamics and pharmacokinetics

The drug is a synthetic analogue of the natural gonadotropin-releasing hormone . He inhibits   allocation luteinizing hormone   pituitary gland, thereby decreasing the level of Testosterone   in men and concentration Estradiol   women. This leads to a regression of prostate tumors and breast cancer. Furthermore, the drug is effective at endometriosis , Preventing the development of follicles   ovarian and fibroma uterus . It leads to a thinning endometrial .

Effective concentrations Zoladex supported by subcutaneous injection every month. The preparation is characterized by a low degree of association with plasma proteins. Half-life, usually - about 3 hours.

Indications

This tool is indicated for:

• hormone-prostate cancer or breast cancer;
• uterine fibroids ;
• need thinning endometrial   before surgery;
• endometriosis ;
• IVF   (if necessary desensitization   the pituitary gland).

Contraindications

The drug is contraindicated in:

• hypersensitivity to its components and other counterparts gonadotropin-releasing hormone ;
• pregnancy ;
• childhood;
• breast-feeding .

Side effects

Side effects while taking Zoladex following:

• CCC: hypotension   or hypertension ;
• Musculoskeletal system: arthralgia ;
• skin rash;
• nervous system: nonspecific paresthesia   and, in rare cases, apoplexy   pituitary;
• Allergy: anaphylaxis   (in rare cases).

The women also identified the following reactions: dryness of the vaginal mucosa, depression , Increased Sweating , Change of mood, changes in libido, changes in breast size, headache . In the early course of patients the presence of breast cancer can be observed hypercalcemia As well as temporarily expressed manifestation of signs and symptoms of the disease. Women with uterine fibroids   In some cases, there is suppression of fibromatous nodes .

The men were also observed following side effects decrease potency , Swollen and painful breasts, Sweating . In rare cases, observed compression of the spinal cord and the violation of ureteral patency. Patients with prostate cancer early in the course sometimes observed transient increase in bone pain.

Instructions for use Zoladex (method and dosage)

The capsules are administered subcutaneously in the abdominal wall. Instructions on Zoladex 3 6mg reported that drug must be used every 4 weeks. In malignant tumors and benign gynecologic pathology course is designed for 6 capsules.

For thinning endometrial   preoperatively two injections administered capsules, the gap between them - 28 days. Ablation   uterine between four and six weeks after the first use of the capsule.

Instructions for use Zoladex 10, 8 mg reported that the drug should be administered every 90 days.

Overdose

Clinically significant adverse events at higher doses of the drug were noted. In case of overdose symptomatic treatment.

Cooperation

Clinically significant effects in combination with other drugs has not been described.

Terms of sale

Zoladex is sold by prescription only.

Storage conditions

Store this medication should be in its original packaging at a temperature of 25 ° C.

Shelf life

Shelf life of the tool is 3 years. Use it after this time is strictly prohibited.

Analogs

Match code ATC 4th level:

• Buserelin Long
• Buserelin Depot
• Diferelin
• Buserelin

Analogs of Zoladex in pharmacies as follows:

• Dekapeptil ;
• Dekapeptil Depot ;
• Diferelin ;
• Sandoz leuprorelin ;
• Lyukrin Depot ;
• Lyuprayd Depot ;
• Eligard .

Among these, particularly common is the last drug.

Which is better - Eligard and Zoladex?

Many patients are wondering which of the two drugs effective: Eligard   or Zoladex. Experts recommend the use of the latter unambiguously. Zoladex has fewer side reactions, moreover, it does not affect driving. So that active drug is often preferred over its equivalents.

With alcohol

Application analogues gonadotropin-releasing hormone   some men may lead to a decrease in bone mineral density. A special risk group patients, who often take alcohol, are long-term treatment Corticosteroid   or anticonvulsant drugs, smoking, and have osteoporosis   at history . Thus, when using Zoladex must be particularly careful. Men who frequently drink alcohol, the drug should be before using consult your doctor.

Reviews of Zoladex

Patients who leave reviews of Zoladex, frequently reported adverse reactions. They write that there headache . frequent menstruation . sleep disorders . The drug, however, helps. Reviews of Zoladex suggests that for those who have been without side effects, the reception of the funds actually turned out to be painless and effective.

Price Zoladex, where to buy

Buy in Moscow and other Russian cities Zoladex 3 and 6 mg may be an average of 8,400 rubles. The cost of the package 10, 8 mg - about 22 000 rubles. Price Zoladex in Ukraine - about 2,000 hryvnia per package of 3, 6 mg, and 6,000 hryvnia per package of 10, 8 mg.

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Mirolyut

Description overdue on 10/07/2014

• Latin name: Mirolut
• ATC code: G02AD06
• Active substance: Misoprostol (Misoprostol)
• Manufacturer: JSC "Obninsk chemical and pharmaceutical company", Russia

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• Composition
• Product form
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• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions on Mirolyut (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Reviews
• Price, where to buy

Composition

The preparation contains 20 mg of active substance - Misoprostol .

Other ingredients that are part of the drug - sodium carboxymethyl starch, prosolv (colloidal silicon dioxide and MCC), magnesium stearate.

Product form

Mirolyut produce a spigot white tablets (sometimes have a yellow or gray shade) risks and beveled. The blisters or plastic jars can be 4, 10, 20 or 30 tablets.

Pharmacological action

Mirolyut prostaglandinopodobnym a means of stimulating labor.

Pharmacodynamics and pharmacokinetics

Misoprostol is a synthetic derivative of Prostaglandin E1 . It causes the expansion of the uterus, and contraction of muscle fibers of the myometrium. Disclosure of the cervix and, respectively, removing the contents of its cavity, facilitated by the ability to stimulate uterine misoprostol.

Mirolyut able to provide a lesser degree stimulates the muscles of the digestive tract. In large doses, Misoprostol   It inhibits the secretion of gastric juice.

No clinically significant effect on the levels of growth hormone, gonadotropin, cortisol, thyroid stimulating hormone, thyroxine, creatinine, on prolactin, lung function, platelet aggregation and the cardiovascular system.

It absorbs quickly. Bioavailability of the substance is reduced, while taking with food (absorption decreases due to fatty foods, absorption length is not changed).

It is metabolized in the liver and the gastrointestinal tract to the walls misoprostol acid . The maximum concentration of the metabolite occurs within 15-30 minutes. The period starts to operate through many drug - 30 minutes and a duration of effect - 3-6 hours. Not accumulates. The half-life - 30 minutes.

Excreted through the kidneys and bowels.

Indications

The drug is prescribed for a medical abortion in conjunction with Mifepristone . Designed for the termination of pregnancy - up to 42 days of amenorrhea.

Contraindications

Medication is prohibited in the following cases:

• kidney disease   and liver ;
• anemia ;
• sensitivity to the components of the drug;
• endocrinopathies , Endocrine disorders (including adrenal dysfunction   and diabetes );
• lactation;
• cardiovascular diseases;
• use IUD   (IUD should be removed before starting);
• hormonal tumor;
• diseases in which prostaglandins contraindicated reception: bronchial asthma . glaucoma . arterial hypertension ;
• diseases that are associated with prostaglandin disease;
• the likelihood of an ectopic pregnancy.

Side effects

During drug administration may arise Mirolyut side effects listed below:

• headache ;
• hyperthermia ;
• vomiting;
• cramping;
• flatulence ;
• skin rash;
• dizziness ;
• nausea;
• diarrhea .

When you receive misoprostol at the recommended doses instruction adverse reactions from the kidneys, liver and the cardiovascular system are not shown.

Instructions on Mirolyut (method and dosage)

Mirolyut tablets taken by mouth. In combination with Mifepristone   should be taken only under a doctor's prescription and under constant supervision in medical institutions obstetrician, if necessary, to specialists to provide emergency surgical and gynecological transfusion support. It requires all the activities that go along with abortion.

Therapy begins with receiving 3 tablets (600 mg) of mifepristone, after 3-4 days prescribed 2 tablets (400 mg) means Mirolyut.

Overdose

In humans the toxicity of the active substance has not been identified. In excess doses can manifest clinical signs: epigastric pain . drowsiness . hypotension . bradycardia . tremor . tachycardia . convulsive reaction . fever , Slowing the heart rate.

Cooperation

Metabolism Misoprostol   stimulated at reception for a long time Isoniazid . Antidepressants . Rifampicin , Anticonvulsants Indomethacin . acetylsalicylic acid , Drugs of the group phenobarbital . Tsimedina . Nicotine , Thereby reducing the level of its content in the blood.

You should not take Aspirin   and other non-steroidal anti-inflammatory drugs for one week after taking the drug Mirolyut.

Antacids interfere with the absorption of the active substance medications Mirolyut. The combination of magnesium-containing antacids and misoprostol can lead to increased diarrhea.

Terms of sale

Buy Mirolyut a pharmacy only if you have a prescription.

Storage conditions

The optimum temperature for storage - 25 ° C, kept in the dark is not a humid place.

Shelf life

Store no more than 3 years.

Cautions

When using the drug for the termination of pregnancy up to 42 days is necessary to combine drugs Mirolyut and mifepristone. Thus, this therapy should be carried out for any other purpose, under the supervision of a specialist doctor in a specialized facility where it is possible to provide emergency surgical and gynecological transfusion support.

The drug requires all the activities that go along with abortion, including the prevention of Rh-factor.

It is necessary to inform the patient about the effects and side effects of the drug before his appointment. For 4-6 hours before taking the medicine the patient should be observed in the hospital. In the event of massive bleeding or other complications during or after treatment, an urgent need to provide medical assistance.

You may experience some vaginal bleeding after mifepristone (some women can last for a long time). At a very early term abortion is possible after taking the drug, but in this case in order to optimize the results you need to take pills Mirolyut. After receiving its abortion occurs within 6 hours in 80% of patients in a week - 10% of patients.

After 8-15 days after taking the medicine need to go to the hospital re-examination. If necessary, carry out or ultrasound to determine the level of human chorionic gonadotropin in the blood. If you suspect to preserve pregnancy or incomplete abortion, should conduct a full medical examination.

Upon detection of incomplete abortion or continue the pregnancy, evaluated 2 weeks after the use of mifepristone, it is necessary to hold vacuum aspiration with histological examination of aspirate as necessary to assess the influence of the formation of congenital malformations in the fetus.

Analogs

By means of having similar pharmacological action include Mizotab   and Misoprostil .

Miropriston and Mirolyut

Preparations Mirolyut Miropriston and can not be regarded as analogues, as they are taken in combination for medical abortion in the early stages. These drugs are used in the treatment and are not interchangeable.

Reviews and Mirolyute Miropristone suggest that strict compliance with the instructions and advice of a doctor, the effectiveness of drugs is quite high. However, when used after 42 days of pregnancy, there is a possibility of complications such as incomplete abortion.

Reviews Mirolyute

Opinion about the preparation of patients is quite controversial: many say the occurrence of side effects, severe bleeding with abdominal pain. Reviews Mirolyute forums indicate that when properly taking the drug, abortion is fairly painless and with a good result. The lower the gestational age, the greater the chance of a minimum of side effects.

Price Mirolyuta where to buy

Tablets Mirolyut can be purchased on the territory of Russia and Ukraine. In Russia, the price Mirolyuta the pharmacy is about 900 rubles (per pack of 10 tablets), the price in Ukraine is about 124 USD. (4 tablets).

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Pyridoxine hydrochloride

Description overdue on 11/12/2014

• Latin name: Pyridoxine hydrochloride
• ATC code: A11HA02
• Active substance: Pyridoxine (Pyridoxine)
• Manufacturer: Tablets - Company "Ozone", Russia. Solution for injection - Borisov Medical Preparations Plant, Belarus.

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for the use of pyridoxine hydrochloride (Method and Dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• With alcohol
• Reviews
• Price, where to buy

Composition

AT   solution for injection   It contains the active ingredient: pyridoxine hydrochloride 0 01 or 0 05 GA as water for injection.

One tablet   composition includes 0, 002, 0, 005, or 0, 01 g of pyridoxine.

Product form

Pyridoxine hydrochloride is produced as a solution for injection packaged in vials of 1 ml, 10 pieces per pack.

The tablets with different content of active substance of 50 pieces packed in cans.

Pharmacological action

The drug has an action, compensates for the deficiency of vitamin B6 .

Pharmacodynamics and pharmacokinetics

Pyridoxine hydrochloride - is vitamin B6,   of great importance for the full metabolism. Once in the body, the substance is phosphorylated and converted into a coenzyme, which is a non-protein organic compound   pyridoxal phosphate-6- Which activates the activity of enzymes. This component is a component of many enzymes necessary for decarboxylation and transamination of amino acids. It is also required for the exchange of lipids - fats, preventing vitamin deficiency in women with pregnancy   and children during active growth.

Indications

Appointed by the drug at:

• nutritional deficiency and secondary pyridoxine;
• toxicosis pregnant;
• postencephalitic parkinsonism;
• some diseases of the nervous system;
• mikrotsiternoy hypochromic anemia;
• radiation sickness;
• acute and chronic hepatitis;
• dermatitis Including children;
• herpes zoster, neurodermatitis;
• exudative diathesis   and so on.

Contraindications

The main contraindication is hypersensitivity to Vitamin B6.

Side effects

Typically, patients tolerate the drug, but it is possible the development of allergic reactions.

Instructions for the use of pyridoxine hydrochloride (Method and Dosage)

According to the instructions for use, tablets intended for oral administration, after a meal. This preventive dosage for adults is - 0, 02-0, 05 mg, for children - 0, 02 mg per day. Therapeutic daily dose for adults is 0, 2-0, 3 mg to reception 1-2 times. When treating children reduced dosage depends on the age.

The drug solution for injection administered at 0, 05-0, 1 gram a day for children at 0, 2 mg for 1-2 receptions. Duration of treatment: adults - 1 month, children - 2 weeks. In the treatment of Parkinson's disease appoint 2 ml per day, the general course of 20-25 injections.

Overdose

No cases of overdose vitamin B6   in medical practice has not been described.

Cooperation

Simultaneous use with   hormonal contraceptives   can increase the amount of pyridoxine in the composition of blood plasma. Vitamin B6 is able to potentiate the action diuretics .

The combination with pyridoxine levodopa   It reduces or completely inhibits the effect of the substance.

Izonikotingidrazid, penicillamine   and cycloserine   may reduce the effectiveness of pyridoxine.

Combined treatment with phenytoin   and phenobarbital   significantly reduce the concentration of these components in the blood plasma.

Terms of sale

The drug is sold without a prescription.

Storage conditions

Keep vitamin need in a dark, cool place, protected from children.

Shelf life

3 years.

Analogs

Match code ATC 4th level:

• Pyridoxine
• Vitrum Vitamin E

This material is a part of such preparations, such as: Adermin, Betsilan, Bedoksin, Benadon, Geksabetalin, Geksabion, Geksavibeks, Pirivitol, Piridobene, Piradoksin . As a part of Magne B6   It contains a combination of magnesium lactate + pyridoxine hydrochloride.

Alcohol

Excessive alcohol consumption is reduced absorption of vitamin B6, increasing the need for him the body.

Reviews on Pyridoxine hydrochloride

As the reviews of pyridoxine hydrochloride, it is often used in clinical practice as part of combination therapy. For example, when: gipovitaminoze B6, leukopenia, atherosclerosis, diabetes, herpes zoster, psoriasis, atopic dermatitis   and so on. In most cases, a marked acceleration of the therapeutic effect.

However, some people are wondering what it is - Pyridoxine hydrochloride? The fact that not all know the name of vitamin B6.

Patients who received active vitamin noted its high efficiency. But sometimes possible development of allergic reactions caused by intolerance to the substance. Therefore, do not take it yourself, as a lack of vitamin B6 to determine only after examination by a specialist.

Price Pyridoxine hydrochloride where to buy

Price Pyridoxine hydrochloride tablets 10 mg 50 pieces is 35-45 rubles.

The solution for injection in vials of 5% can be purchased at a cost of 20 rubles.

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