Description overdue on 05/20/2014
- Latin name: Vitrum Century
- ATC code: A11AA04
- Active substance: Multivitamins in combination with trace elements
- Manufacturer: UNIPHARM, Inc., USA
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Vitrum Centuria
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One tablet contains:
- acetate, retinol (vitamin A) and betakaroten - 6000 IU (corresponds to the content retinol acetate and - 2 mg betakarotena - 112 g);
- alpha-tocopherol acetate (vitamin E) - 45 IU (45 mg);
- phytomenadione (vitamin K1) - 10 g;
- cholecalciferol (vitamin D3) - 400 IU (10 micrograms);
- ascorbic acid (vitamin C) - 60 mg;
- thiamine hydrochloride (vitamin B1) - 1.5 mg;
- pyridoxine hydrochloride (vitamin B6) - 3 mg;
- Riboflavin (vitamin B2) - 1.7 mg;
- pantothenic acid (as calcium pantothenate - Vitamin B5 ) - 10 mg;
- nicotinamide (vitamin PP) - 20 mg;
- cyanocobalamin (vitamin B12) - 25 g;
- Folic acid (vitamin B9) - 200 g;
- calcium ( as calcium hydrogen phosphate ) - 200 mg;
- Biotin (vitamin H) - 30 g;
- magnesium (as magnesium oxide ) -100 Mg;
- potassium (as potassium chloride ) - 80 mg;
- phosphorus (as calcium hydrogen phosphate ) - 48 mg;
- copper (as copper oxide ) - 2 mg;
- iron (as iron fumarate ) - 9 mg;
- manganese (as manganese sulfate ) - 2.5 mg;
- zinc (as zinc oxide ) - 15 mg;
- iodine (as potassium iodide ) - 150 g;
- selenium (as Sodium selenate ) - 20 g;
- boron (as sodium borate ) - 150 g;
- nickel (as nickel sulfate ) - 5 g;
- chrome (as chromium chloride ) - 100 g;
- molybdenum (as sodium molybdate ) - 25 mg;
- vanadium (as sodium metavanadate ) - 10 g;
- chloride (as potassium chloride ) - 72 mg;
- silicon (as sodium metasilicate ) - 10 micrograms.
Part Vitrum centuries Forte further includes:
- tin (as tin chloride ) - 5 g;
- lutein - 100 g;
- leaf plants Ginkgo Biloba in powder - 20 mg.
As auxiliary substances are used: microcrystalline cellulose, stearic acid, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate .
The structure of the shell consists of: hypromellose, triacetin, titanium dioxide Black dye, yellow dye sunset, red dye charming.
Product form
The drug is available in the form of kapsulovidnyh coated tablets film-gray, with a dividing strip on the edge; on the side section - the core of straw color, with dark or light inclusions; possible presence of a specific flavor. The plastic bottles of 30, 60, 100, 120 or 130 such Tablets (for Vitrum Centuria ) In blisters of 30 tablets (for Vitrum centuries Forte ). One such vial or 1, 2, 3 of blisters in a carton box.
Pharmacological action
Fill gaps vitamins and minerals .
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Vitrum Centrum belongs to a group of medicines called multivitamin or multivitamin preparations. Composition contains all vitamins and minerals in doses necessary for the elderly after 50 years. Increases resistance to disease, common in this age, increases physical and mental performance. Reduces the risk of cancer and heart disease, prevent premature aging.
- Vitamins A, E, C, beta-carotene, selenium, zinc, copper and manganese are antioxidants protecting cell components, including chromosome From damage by oxygen radicals.
- Vitamin A elderly people responsible for T- and B-cell-mediated immunity As well as to accelerate the synthesis of Cytokine . Retinoic acid It supports activity of killer cells that play a major role in anti-viral and anti-cancer protection.
- Betakaroten It is used in the body for constructing the molecules vitamin A It prevents damage to the cell membrane lipid peroxidation products.
- Ascorbic acid - A powerful antioxidant, increases nonspecific resistance of the organism.
- Vitamin E - Is also a powerful antioxidant, it is used in the biosynthesis Hemoglobin and proteins that affect the state of the vessels.
- Selenium It is converted in the body glutadionperoksidazu That protect cells and tissues from organic hydroperoxides.
- Vitamins B1, B2 and B6 play an important role in normalization of protein, fat and carbohydrate metabolism.
- Vitamin B1 It contributes to the proper functioning of the biochemical processes of the nervous, endocrine and cardiovascular systems.
- Riboflavin - Component flavin enzymes Providing tissue respiration and the formation of molecules ATP in cells, as well as numerous high-cost energy redox processes.
- Vitamin B6 involved in the metabolism glycogen . amino acids . sphingoid bases and products neurotransmitters .
- Nicotinamide - A component of proteins dehydrogenases carrying hydrogen ions in the cells.
- Pantothenic acid involved in the process of restoring the endothelium and the exchange of fatty acids.
- Cyanocobalamin needed for the production of nucleotides, and fatty acid metabolism, passing methylation processes in cells. Together with folic acid plays an important role in the maintenance of hematological and nevrologicheskgo homeostasis.
- Folic acid CoA molecules is responsible for synthesis and breakdown of amino acids and nucleic acids. Use the required amount of folic acid is the prevention of a number of cancers, particularly cancer of cancer of the colon and rectum, lung, esophagus, stomach.
- Vitamin K1 used for prophylaxis osteoporosis Possesses anti-inflammatory and anti-sclerotic effect, controls the level of glucose in the blood and improves the clinical picture Alzheimer .
- Vitamin D . copper, calcium, magnesium, manganese, zinc and boron play an important role in the prevention of osteoporosis (brittle bones).
- Iodine - An important component of the hormones Thyroid Supporting the proper functioning of many metabolic processes, maintain immunity.
- Iron - Part hemoglobin a , Carries oxygen to organs and tissues, and cellular respiration, and many other proteins ( myoglobin flavoproteins, transferrin, lactoferrin, hemosiderin ). It improves appetite, stimulates the processes of reconstruction and recovery.
- Molybdenum molecules involved in building sulfitokinazy, ksantooksidazy and aldehyde Responsible for the destruction of certain amino acids and heterocyclic bases ( purines and pyrimidine ). These processes affect the body's neurological status.
- Chrome enhances the effect of insulin .
- Nickel in special proteins regulate iron metabolism.
- Silicon - Building material for bones and Collagen .
At Vitrum centuries Forte additionally contains:
- Lutein - Prevent vision loss and improves sharpness;
- leaf powder plant Ginkgo Biloba - A proven means of boosting cognitive function (memory score, attention, etc.) in the elderly;
- tin - It improves recovery processes, regulates the activity flavin enzymes , A component of the molecule gastrin .
Pharmacokinetics
Pharmacokinetics studies have not been conducted.
Indications
Prevention and treatment of vitamin and mineral deficiencies in the elderly, including:
- during mental and physical exertion;
- during the treatment and rehabilitation of an illness;
- unbalanced nutrition.
Contraindications
Hypersensitivity to the drug and its components; hypercalcemia, gipermagniemiya, hypercalciuria, nephrolithiasis, active tuberculosis lung sarcoidosis a history hypervitaminosis A, E and D . thrombophlebitis , Fructose intolerance, gout , Metabolic disorder of copper or iron, severe renal dysfunction, hyperuricemia, erythremia, chronic cardiac insufficiency . thyrotoxicosis . stomach ulcers and 12 duodenal ulcer (possible increase in acidity), the joint use of retinoids, selenium .
Side effects
- On the part of the immune system: possible reactions hypersensitivity Including anaphylaxis . angioedema Temperature increase in persons with allergies.
- For the skin rash, hives , Redness of the skin, itching.
- From the gastrointestinal tract: nausea, dyspepsia, abdominal pain, belching, diarrhea , Constipation, gastric hyperacidity, heartburn.
- On the part of the central nervous system: dizziness, headache, irritability, drowsiness.
When long-term reception in high doses may occur: irritation of the digestive tract, hypercalcemia, paresthesia, hyperuricemia, hyperglycemia, impaired renal function, a temporary increase in liver enzymes and alkaline phosphatase , Dry skin, seborrheic rash, hair loss.
Instructions on Vitrum Centuria
Instructions for use Vitrum centuries Forte is no different from the instructions on the Vitrum centuries and prescribe oral 1 tablet a day after meal. The course of treatment is 3 months. Prescribed by a doctor may be held refresher courses.
Overdose
No reported cases of overdose. Iron overdose include nausea, diarrhea , Abdominal pain, lethargy. Occurrence hyperglycemia and and acidosis .
Treatment of overdose: gastric lavage, symptomatic therapy.
Cooperation
Since Vitrum centuriae composition contains iron and calcium in the relevant sections of the digestive system may decrease absorbability antibiotics tetracycline group and fluoroquinolones . Ascorbic acid enhances the effects of sulfonamides . Antacids Comprising magnesium, aluminum, calcium, reduce the absorption gland . Iron supplements and silver lower bioavailability Vitamin E . Folic acid activates metabolism phenytoin .
Terms of sale
The drug is available without prescription.
Storage conditions
Store at temperatures up to 30 degrees of the reach of children.
Shelf life
36 months.
Cautions
Caution should be prescribed the drug for liver and kidney, gastric ulcer and 12 duodenal ulcer in past, diabetes . cholelithiasis . pancreatitis .
The drug should not be prescribed the drug, along with other multivitamin complexes, as there may be an overdose.
Analogs
Berocca Plus
Pikovit D
Biovital Kinder
Eleven Pronatal
Duovit women
Duovit Energy
Duovit
Intensive Selmevit
Selmevit
Triovite
Vitrum with beta-carotene
Vitrum Baby
Vitrum Prenatal
Vitrum
Vitrum Junior
Vitrum Kids
Menopace
Analogues of drugs are vitamin complexes close or identical composition: Vitrum Prenatal . Multimaks Kinder . Multimaks Prenatal, Oligovit, Supervit and others.
Babies
Not recommended for use in children.
During pregnancy and lactation
Investigation of the influence of the drug during pregnancy and lactation has not been, therefore, should refrain from taking the drug in these states.
Reviews of Vitrum Centuria
Reviews of vitamins fixed numerous cases confirm the claimed effect in patients applies Vitrum Centrum after 50 years.
Price Vitrum Centuria
In Russia, the average price Vitrum centuries Forte (30 tablets) is close to 415 rubles, Vitrum Centuria -380 Rubles; Ukraine 79 and 70 hryvnia respectively.
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