Description overdue on 08/18/2014
- Latin name: Xylen
- ATC code: R01AA07
- Active substance: Xylometazoline (Xylometazoline)
- Manufacturer: The Russian company "LENS-PHARM"
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Xylene (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
The composition of xylitol
Nasal drops: 1 ml containing 1 mg ksilometazolina in hydrochloride form and additional components: disodium hydrogenphosphate dodecahydrate, benzalkonium chloride, disodium edetate and water.
Nasal Spray: in 1 ml of composition included 0, 5 mg ksilometazolina .
Product form
Nasal drops produced in special droppers, vials of amber glass or polymer materials. Each carton box - 1 bottle.
Nasal Spray produced in special flasks (10 mL standard volume).
Pharmacological action
The drug has a local dekongestantnoe impact (vasoconstrictor effect). Active ingredient refers to alpha-agonists and when administered intranasally causes narrowing of the blood vessels in the nasal mucosa, reducing congestion and swelling in the rhinitis . rhinitis .
If nasal congestion drug eases breathing and reduces the severity of rhinorrhea .
Pharmacodynamics and pharmacokinetics
Effective action medicament recorded 3-5 minutes after application and lasts for 8-10 hours. Systemic absorption ksilometazolina is minimal when administered intranasally.
Indications
Nasal drops Xylene is prescribed for acute rhinitis ( allergic genesis At SARS ) As a symptomatic therapy.
The drops in the nose Xylene are used in otitis media and sinusitis to reduce the severity of nasal congestion (mucous membranes).
What drops Xylene can be used more? In preparation for rinoskopii and to diagnostic procedures in ENT practice.
Contraindications to the use of xylitol
- atherosclerosis (Severe);
- tachycardia ;
- glaucoma ;
- chronic form of rhinitis;
- hypertonic disease ;
- atrophic rhinitis ;
- Individual hypersensitivity;
- surgical treatment of meningitis in the past.
Xylene is prescribed with caution in:
- benign prostatic hyperplasia ;
- coronary heart disease ;
- hyperthyroidism ;
- diabetes .
Contraindications in pediatrics: Spray 0, 05% is not indicated for patients under the age of 2 years.
Side effects
Nose drops well tolerated. Rarely observed hypersecretion , Dryness and irritation of the mucous membranes in the application, paresthesia . bouts of sneezing , climb blood pressure . tachycardia .
In a few cases recorded insomnia . migraine , Swelling of the nasal mucosa, depression . heart rhythm disturbances , Of the visual perception.
Long-term treatment causes atrophic changes and the development of edema.
Instructions on Xylene (method and dosage)
The drug is used alone intranasally.
Instructions for use xylitol: before applying the drug to the nasal passages clean of accumulated mucus, then enter with a dropper on the bottle 1-2 drops in each nostril. Multiplicity - 3 times a day. The nozzle after each use should be thoroughly washed, and the vial tightly capped. Nasal drops can be used no more than 5 days. Nasal drops can be used in pediatric practice reaches 6 years. Children Xylene is not developed.
Spray appoint 1 spray in each nostril 1-2 times a day. After use, the nozzle is washed vial tightly capped. Duration of treatment - 5 days.
Overdose
Long-term treatment with high doses can lead to convulsions , Unstable blood pressure, depression . tachycardia . Specific antidote does not exist. It recommended posindromnaya therapy, stabilizing the heart and blood vessels.
Cooperation
Do not combine with tricyclic antidepressants.
Monoamine oxidase inhibitors It should not be administered concurrently with ksilometazolina (timeslot - 2 weeks).
Terms of sale
OTC medicines.
Storage conditions
The temperature range of 15-25 degrees.
Shelf life
3 years.
Analogs
Tizin Xylo
Rinonorm
Rinostop
Naphazoline
Otrivin
Sanorin
Nazivin
Galazolin
Noksprey
Naphthyzinum
Structural alternatives: Galazolin . Ksilobene . Xymelin . Dlyanos . Otrivin . Rinonorm .
Babies
For children not developed a special type of issue - Children Xylene . In pediatrics can use only 0, 5% solution.
Xylene in pregnancy and lactation
Not recommended for use when Xylene pregnancy . The consequences can affect the development of the fetus. In the acute need for the medication during lactation it is recommended to resolve the issue of termination breast-feeding .
Reviews of xylene (overview)
Subject forums contain positive comments on the application of ksilometazolina at rhinitis and colds .
Reviews of xylene in pediatrics: the medication quickly relieves runny nose and helps to restore nasal breathing.
Price xylitol, where to buy
Nasal Spray It costs about 40 rubles nasal drops - 25 rubles. Children Xylene (a drop of 0, 05%) - 22 rubles per bottle. Price xylitol depends on the pharmacy network and the region.
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