Djufaston

Description overdue on 07.04.2012

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Progestogens means . The active substance is didrogesteron . The drug acts selectively on the endometrium. Base material helps to normalize the function of the secretory endometrium after previous use of estrogen. Duphaston has no estrogenic, androgenic and glucocorticosteroid activity. The drug reduces the contractility, excitability of the muscles of the uterus and fallopian tubes. Didrogesteron not cause virilization mother masculinization   in females. Available in tablet form.

Indications:

Duphaston prescribed for infertility Caused by insufficient luteal system. The drug is effective in progestin failure   (habitual abortion dysmenorrhea . threatened abortion ), With dysfunctional metrorrhagia Secondary amenorrhea   (complex therapy in conjunction with estrogen), endometriosis, premenstrual syndrome. During Menopause   a drug prescribed as a hormone, replacement therapy. In postmenopausal Duphaston is indicated for the prevention of side effects of unbalanced estrogen in the endometrium.

Contraindications:

Djufaston not indicated intolerance of dydrogesterone. If Rotor syndrome, Dubin-Johnson syndrome, Gilbert, congenital hyperbilirubinemia , Chronic renal pathology system, skin itching during pregnancy Duphaston prescribed after consulting experts.

Side effects, overdose symptoms:

Duphaston can cause metrorragii , Dizziness, stool, diarrhea, nausea. In overdose recorded sudden bleeding, dizziness, and vomiting. Treatment is carried out in accordance with the syndromes.

Mode of application:

Dosing of the drug Duphaston produce depending on the severity, the features of the underlying disease, the presence of comorbidities .  Infertility in the luteal insufficiency: 14 to 25 day cycle 2p per day, 5 mg .  Dydrogesterone treatment was carried out for six consecutive cycles .  Djufaston pregnancy must continue to take in the first five months of the scheme: twice a day, 5 mg .  Threatened abortion: single dose of dydrogesterone 40, then take the drug twice a day for 10 mg .  When you save a threatened miscarriage dosage is increased by 5 mg every vocem hours .  On reaching effect on the scheme Djufaston take seven days, gradually reducing the dosage .  Habitual abortion: therapy begins before conception, the woman must be taken twice a day for 5 mg from the 14th to 25th day of the cycle .  Admission didrogesterona if pregnancy occurs continue along the same lines of up to 20 weeks, after which the dose is gradually reduced .  Dysmenorrhoea: from 5 to 25 day cycle Djufaston taken twice a day, 10 mg .  Endometriosis: 2-3 times a day by 10-30 mg from the 5th to 25th day of the menstrual cycle .  Irregular menstrual cycle: twice a day for 5 mg, the course lasts from 11 to 25 day menstrual cycle .  Amenorrhea: treatment combined with etilestradiolom a dose of 0, 05 mg, treatment is carried out with 11 to 25 day cycle, take the drug twice a day for 5 mg .  Functional uterine bleeding: a combination with ethinyl estradiol at a dose of 0, 05 mg of the drug take 5-7 days four times a day .  After stopping the bleeding is carried out preventive treatment: 11-19 days of the cycle - once a day, 19-25 day cycle - twice daily .  Postmenopause: last 12-14 days of each cycle of 10-20 mg per day .  Acceptable combination of estrogen scheme .  The daily dosage of the drug Duphaston is distributed throughout the day .  When assigning different doses of therapy begins with a large dose .

Special instructions:

Phenobarbital, Inductors of microsomal oxidation   in the hepatic system significantly reduce the effectiveness of the drug Duphaston, accelerate metabolism. Use of the drug during pregnancy is possible Djufaston indicated.