Atsekardol

Description overdue on 07/11/2013

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Antiplatelet agents . Active substance - acetylsalicylic acid . The mechanism of action is the possibility of inhibiting cyclooxygenase active ingredient that causes inhibition of production of thromboxane A2, decreased platelet aggregation of cells. Achieved a single oral antiplatelet effect lasts for weeks. High dosages of the drug can exert an analgesic and antipyretic action (over 300 mg). Tablets Atsekardol produced a dose of 50, 100 and 300 mg. The drug is completely absorbed in the digestive tract and is only partially metabolised in the absorption process. Analogs Atsekardola: TromboASS, Cardiomagnyl, Aspinat, Atsenterin, Aspirin. Buy Atsekardol possible at a pharmacy without a prescription.

Indications:

Atsekardol prescribed for unstable angina to prevent recurrent myocardial infarction, for prevention pulmonary embolism   (including its branches), and deep vein thrombosis (for longer stays in the stationary state, e.g., during long surgery). The drug is prescribed for patients with risk factors (increased body weight, high cholesterol, diabetes , Smoking, age, hypertension) for the prevention of acute myocardial infarction. Instructions for use Atsekardola recommends medication to patients after invasive surgery and angioplasty (stenting, carotid angioplasty , Carotid endarterectomy, coronary artery bypass surgery, arteriovenous shunting) for the prevention of thromboembolism. The drug is prescribed for patients with transient disturbances of blood supply to the brain to prevent stroke, ischemic type.

Contraindications:

The drug is not prescribed to patients with erosive and ulcerative diseases of the digestive tract, with bleeding diathesis , Bleeding from the stomach, duodenum. The drug is not prescribed for asthma caused by intake of salicylates. The drug is contraindicated in diseases of the liver, Heart Failure , In the pathology of renal system through breastfeeding. Inadmissible simultaneous treatment with methotrexate at a dose higher than 15 mg per week. Application Atsekardola limited in patients with hyperuricemia, gout, drug allergies, hay fever, nasal polyposis. Aspirin can cause bleeding during surgery.

Side effect:

The digestive tract:   increase the level of enzymes ALT and AST, vomiting, heartburn , Nausea, ulcerative lesions and bleeding. Hematopoietic system : anemia , The risk of bleeding due to inhibition of platelet aggregation of cells. Allergic responses   as cardiorespiratory distress, swelling of the mucous wall of the nasal cavity, rhinitis, urticaria, angioedema, pruritus and rash. Rarely have severe allergic-type anaphylaxis . Respiratory system:   bronchospasm small and medium caliber. Nervous system:   violation of auditory perception, tinnitus, headaches, dizziness.

Mode of application:

Atsekardol advised to take before meals. Tablets desirable drink sufficient volume of liquid. The drug is prescribed for a long time. Multiplicity of reception - 1 times a day. For suspected acute myocardial infarction to prevent appoint 100 mg daily or 300 mg every other day. Chewable tablet provides a more rapid effect, which is very important in the early hours of myocardial infarction. In the presence of several risk factors for the prevention of new-onset acute myocardial infarction prescribed 300 mg a day or 100 mg daily. Warning unstable angina, reinfarction, prevention of transient ischemic blood circulation, ischemic stroke 100-300 mg daily. For the prevention of pulmonary embolism, deep vein thrombosis is prescribed 300 mg a day or 100 mg daily

Special instructions:

Atsekardol may provoke bronchospasm and bronchial asthma. Risk factors: a history of nasal polyposis, hay fever , Drug allergies, asthma. The achieved effect of inhibiting platelet aggregation is maintained for a few days, which may cause bleeding at an emergency surgery. Before elective surgery medication canceled at least 7 days. In predisposed patients Atsekardol in small doses may cause gout. At risk persons with reduced excretion Uric acid . At higher doses significantly increases the risk of digestive tract bleeding. Atsekardol no effect on the ability to drive. When treating glbkokortikosteroidami be aware that when they are canceling the possibility of overdose with salicylates. It is unacceptable to use the drug to pregnant women, especially in the 1 and 3 trimesters. Price Atsekardola - up to 100 rubles.

Drug Interactions:

Atsekardol able to enhance the effect of Heparin . Methotrexate , Anticoagulants indirect effects (due to functional abnormalities in platelets), antiplatelet agents, and thrombolytic medicines Digoxin   (due to lower its renal excretion system), hypoglycemic agents, valproemoy acid (based on its mechanism of displacement due to plasma proteins). The risk of bleeding is increased by the use of antiplatelet agents, thrombolytics, and antikoagulnyatnyh funds. There is a growing toxic effects of ethanol on the work of the brain and nervous system, while the use of alcohol. Atsekardol able to weaken the action and other urikozuricheskih benzbromarina Drug Administration (mechanism based on the competitive reduction of renal excretion of uric acid in the tubules), diuretics (due to lower filtration rate at the level of the glomeruli), ACE inhibitors. Systemic steroids weaken the effect Atsekardola by increasing the elimination of salicylates.