Description overdue on 12.12.2014
- Latin name: Kagocel
- ATC code: J05AX
- Active substance: Kagocel (Kagocel)
- Manufacturer: NEARMEDIC PLUS (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Kagocel (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Kagocel for the children
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
- Composition of 1 tablet comprises:
- Kagocel (the main biologically active component) - 12 mg;
- potato starch - 10 mg;
- calcium stearate - 0, 65 mg;
- ludipress (direct compression lactose, a mixture of lactose monohydrate, povidone (Kollidon 30) and crospovidone (Kollidon CL)) - up to 100 mg.
Product form
The pharmacy medicine can be found in the form of lenticular round tablets cream-or brown color with small impregnations. Contour cell blister contains 10 pieces. The carton is put 1 record.
Pharmacological action
Kagocel (INN - International Nonproprietary Name) - antiviral drug that is a synthetic organic complex sodium salt obtained by the synthesis of water-soluble polyphenols Karmoksimetiltselyullozy and cotton seeds. That is, based on the active component of the drug is a certain proportion plant compounds . As an interferon inducer, Kagocel has the following therapeutic properties:
- immunomodulatory;
- antimicrobial;
- antiviral;
- radioprotective .
Wikipedia , The free encyclopedia of knowledge on the Internet, argues that mechanism of action pharmaceutical preparation is very simple. He based on the ability components medicament stimulate education of the different species interferon, Natural proteins defenders the body, as the specific structure of the protein to activate the enzyme systems of oppression harmful microflora and viral colonies. Interferons also able to suppress tumor activity in its bud. Sphere of influence Kagocel extends to macrophages, T and B lymphocytes, granulocytes, endothelial cells, and even fibroblasts.
Pharmacodynamics and pharmacokinetics
On the passage of the day (24 hours) since the introduction of Kagocel the body, basic biologically active components medicament accumulate in liver, lung, thymus, spleen, kidney and lymph nodes That is, bodies which are more or less immune exhibit properties against harmful pathogens coming from the outside. Low concentration constituent elements of the drug is observed in the myocardium of the heart and other muscle, adipose tissue, testis, brain, and blood plasma.
The titer of interferon serum increases gradually and reaches the maximum numbers after 48 hours using tablets. AT intestine same dynamics of accumulation of of antiviral of proteins is much higher - maximum production of interferon It notes in 4 hours. Because monitor the effectiveness of the drug recommended by examining the contents of the lumen of the digestive tube and the activity of its cellular structures.
Therapeutic effect It characterized as long as the answer interferons conserved during 4-5 days , During which the protective proteins continue to circulate in the bloodstream of the main and small vessels. Because of this the greatest efficiency in the conservative treatment of a pharmaceutical preparation is observed at his appointment no later than the 4th day from the beginning of the current acute infectious process.
Indications
- Flu;
- acute respiratory viral infections ;
- prevention of colds ;
- simple herpes in adult patients.
Contraindications
- increased individual sensitivity to the constituent components of the pharmaceutical formulation;
- period pregnancy and breast-feeding ;
- hereditary or acquired intolerance drug;
- age category of patients up to 3 years;
- enzymatic disorders digestive system - lactase deficiency, lactose intolerance, glucose-galactose malabsorption.
Side effects
Adverse effects from the use of the drug is extremely rare and usually limited allergic reactions . However, if the patient is watching at any of the side effects of the active components of a pharmaceutical preparation, immediately consult a qualified physician.
Instructions for use Kagocel (method and dosage)
Tablets Kagocel, instructions for use
In the summary the manufacturer indicates that the use of the drug should be orally , Not chewing a pill, as well gulping it entirely. You can wash down with plenty of liquid, but do not keep it long in the mouth. The dosage and duration of treatment is usually selected individually empirical way, but there are also common therapeutic regimens that doctor should be seen as practical advice.
How to drink for adults?
From a therapeutic purpose acute respiratory viral infections . Flu or influenza-like diseases administered 2 tablets three times a day for the first two days, and the following 2 days, 1 tablet three times a day. Term dosage - 18 tablets, and the duration of the treatment - 4 days. As the take - up or after a meal - adult organism has no practical significance, since the absorptive capacity of the biologically active components of a pharmaceutical drug does not change with the arrival of food in the cavity of the gastrointestinal tract.
The medicament may be used as preventive . Preventive rehabilitation Which held a 7-day cycle. The course is divided into two phases. First, active when given 2 tablets 1 time daily for 2 days, and the second, passive, is a 5-day break (the time during which the active ingredients are able to realize their therapeutic effects). Then, if necessary, can be repeated prophylactic.
Instructions for use for children
In the age category from 3 to 6 years - 1 tablet 2 times a day for the first 2 days and for the next 2 days 1 1 tablet once a day. Total children's therapeutic course for the youngest is 6 tablets admission lasting 4 days.
At the age of more than 6 years prescribed 1 tablet 3 times a day for the first two days, and the next two days - one tablet 2 times per day. Accordingly the duration of conservative sanation has not changed and amounts to 4 of the day, as well dosage of of a pharmaceutical preparation has grown up to 10 tablets.
The medicament means may used prophylactically and in pediatric patients. The biphasic dosing scheme remains, however, the dosage is reduced to 1 tablet 1 per day for the first two days.
How to take Kagocel herpes?
Since the pharmaceutical activity Kagocel applies to viruses and the immune system, respectively, the drug can be used by adult patients categories not only for the treatment of colds viral etiology, but also to eliminate unpleasant herpes sores. How to drink tablets herpes - appointed 2 tablets 3 times a day for 5 days. Heading dose - 30 tablets.
Overdose
As side effects, overdose clinical condition is very rare and is accompanied by bouts of nausea and pain in the upper abdomen. In case of these symptoms it is recommended to clean the gastro-intestinal tract of tablets Kagocel by artificially induced vomiting. Next is assigned excessive drinking and other elements detoxification therapy .
Cooperation
Clinically significant interactions are currently not identified and not described in the medical literature.
Terms of sale
Abstract to the drug claims that the pills are freely available in the pharmacy, that is, the drug can be purchased without a prescription.
Storage conditions
Saves tablets out of the reach of children at or above 25 degrees Celsius.
Shelf life
2 years
Cautions
Kagocel - an antibiotic or not?
The drug has strong antimicrobial, antiviral and immunomodulatory therapeutic effects, from which tablets can be perceived by the townsfolk, as an antibiotic. But from the clinical pharmacology it is not quite true, because in the definition of this group of pharmacy products is a key natural or semi-natural origin active ingredients. Kagocel, in turn, is Synthetic derivatives plant components, allowing research scientists to combine the best qualities of cough and cold medicines in one tablet.
The analogue Kagocel
Izoprinozin
Allokin Alpha
Panavir
Ingavirin
Groprinosin
Amizon
Anaferon
Arbidol
Antiviral medicines - an extremely large group of pharmaceutical products, which are usually in the pharmacy does not take the same shelf, respectively Kagocel has a very extensive list of peers (peers meant by drugs with the same international non-proprietary name or a similar code system ATC). To replace Kagocel may be used: Aveol . Aqua Maris . Bitsiklol . Vazonat . Glycyram and many others.
Kagocel refers to expensive antiviral pills because separately should consider whether there is an analogue Kagocel cheaper or not. The answer is largely depending on the country accommodation and purchase the drug. For example, in Ukraine as a medicament for respiratory diseases can be used Abyufen . Avioplant , Atoxil, Bronhostop The cost of which varies depending on the pharmacy network, but always below the market price Kagocel. In the Russian Federation more accessible analogue acts Anaferon .
Also included as analogs Kagocel addresses many pharmaceuticals which have a therapeutic effect is not identical, but similar end result with Flu antiviral drug.
What is better - or Kagocel Ingavirin?
Ingavirin - is popular in the winter time a pharmaceutical preparation, characterized by a pronounced antiviral activity against the most common pathogens of acute respiratory infections such as influenza virus types A and B, and a pair of influenza, respiratory syncytial virus group, adenovirus and many others. Its mechanism of action based on the ability of the biologically active components to affect processes of reproductions of and the resumption of malicious agents. Also, medicament in the form capsules is credited with strong anti-inflammatory the impact of on the human body.
Undoubtedly, the pharmaceutical drug is effective in the conservative rehabilitation of colds to confirm the origin of the pathogen, but as not specific therapy When set etiological component of the pathology is not possible, use Ingavirin is not rational. Kagocel wins and another point, namely, preventive measures Because the drug is actively used for the prevention of respiratory infections in winter than, unfortunately, can not boast Ingavirin.
What is better - or Kagocel Arbidol?
Arbidol as Kagocel is an antiviral drug, the therapeutic usefulness of which is to increase the production of natural interferon, warring against the invasion of pathological agents. In addition, the active ingredients of the drug stimulates cellular and humoral immune responses that a positive effect on the body's resistance to viral respiratory infections.
List side effects Arbidola as short as in Kagocel, but unlike the latter, is included in the pharmaceutical preparation List B (Register of Medicinal Products, the purpose of which must be done with extreme caution, as may develop unforeseen complications when used without careful medical supervision), which in itself is alarming. If you decide to undergo conservative therapy or preventive sanitation "on his feet" (without official registration of sick leave), it definitely should choose Kagocel.
What is better - or Kagocel Amiksin?
Amiksin an effective synthetic interferon inducer, that is, the mechanism of action is similar to Kagocel tablets because the drug increases the formation of the active antiviral agent of intestinal epithelial cells, hepatocytes, lymphocytes by some factions. A distinctive feature of Amiksina - is the speed of onset therapeutic effects , Soft immunomodulatory effects observed already after 4-24 hours after dosing. Accordingly, its use is more efficient in Urgent conservative rehabilitation adult patients age category.
In pediatric practice pharmaceutical formulation has not acquired such widespread popularity, as in the summary there is a contraindication to the use of tablets Amiksin to 7 years. So, in the treatment of children of younger age segment preference should be given Kagocel, the use of which can be started from 3 years old.
Kagocel or Ergoferon: which is better?
Ergoferon - A drug with an unusually wide range of therapeutic action, which, in addition to selective antiviral and immunomodulatory effects, including antihistamine and anti-inflammatory components. Clinical rational use of pharmaceutical preparation proved on many points. For example, the list of pathogens of respiratory infections, which are defeated after using the pills Ergoferon much more than that Kagocel.
Separately, it is noted that Ergoferon can apply as in medical therapy for adult patients and pediatric since the age of 6 months. Based on these facts, the pharmaceutical preparation can be considered better Kagocel, but the price analogues of this level, of course, higher.
Kagocel for the children
The pharmaceutical preparations of the active used in pediatric practice, since its therapeutic range covers one of the most comprehensive pieces of children's nosology. Acute respiratory infectious diseases, bacterial or any other origin occur very often, because children Kagocel already appointed 3 years . Summary of drug assures safe as the early use of the drug, and grateful responses from parents only confirm this fact.
How to take the children can be found in the section with instructions specifying the exact dosage of a pharmaceutical preparation for different ages. You should also pay attention to the possibility of preventive use of the drug for the prevention of colds and acute respiratory diseases in children are found everywhere.
Kagocel and alcohol
According to the mechanism of action and pharmacokinetic ability Kagocel active ingredients, the drug can not be directly reacted with the components of alcoholic beverages. Yet endogenous interferons , Develops under the influence of antiviral tablets have a negative, inhibitory effect on the central nervous system. That is immune agents can provoke the development of certain mental and neurological disorders (most often - retinopathy . neuropathy , Prolonged depression and so on).
Typically, these adverse effects are manifested conservative treatment asthenic disorders - Excessive fatigue, weakness, drowsiness, decreased alertness, impaired ability to concentrate , However on the background of of acute respiratory disease such side effects are not noticed, after all they are similar with the clinical symptomatology virtually any colds nosological unit.
If you mix alcohol and Kagocel, such manifestations are mutually enhanced (for influence of alcoholic beverages on the central nervous system characterized by the inhibitory effect), because between the end of medical treatment and the use of alcoholic beverages must pass at least 5 days .
During pregnancy (and lactation)
No reliable clinical studies on the effect of active components of a pharmaceutical preparation in the woman's body and the developing baby in the womb is not carried out, because the decision to use the drug taken individually. Most practitioners are inclined to replace the tablets other antiviral drugs during pregnancy and the inclusion of the condition of the female body in Contraindications Kagocel to use. A similar opinion of qualified specialists and in occasion of of breastfeeding - if there is the opportunity to, should be avoid the application of the given a medicament.
Reviews Kagocel
The antiviral pharmaceutical preparation uses wide popularity among patients of pulmonary and therapeutic departments.
allergic reactions .
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