Description overdue on 06/09/2014
- Latin name: Artradol
- ATC code: M01AX25
- Active substance: Chondroitin sulfate (Chondroitin sulfate)
- Manufacturer: Inkamfarm (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The drug has a composition of 100 mg Sodium chondroitin sulfate .
Product form
The medicine comes in the form lyophilisate Which is used to prepare a solution for administration by intramuscular injection. The vial contains 2 ml of product. The cardboard package contains one holder of cardboard, contains 10 ampoules or two plastic pallets, each of which has a capacity of 5 ampoules.
Lyophilizate - It is white or yellowish porous mass, which is sealed into tablets.
Also available ointment Artradol 5%, which is applied topically. Implemented in glass jars 30 g, packed in a pile of cardboard.
Pharmacological action
Active ingredient chondroitin sulfate It is a major component of the proteoglycans which together with collagen fibers form cartilage matrix. In preparation marked chondroprotective properties. He has the ability to reduce the activity of the enzymes that trigger the processes of degradation of articular cartilage. Also under its influence there is stimulation of proteoglycan production by chondrocytes and enhanced metabolism in the cartilage and subchondral bone. Artradol facilitates the exchange of Calcium and Phosphorus in cartilage and contributes to the regeneration of the active and participates in the formation of cartilage and bone.
The drug has analgesic and anti-inflammatory properties.
Under the influence of the drug decreases the release of mediators of inflammation, reduces the secretion of prostaglandin E2 and leukotriene B4.
Thus, the resistance Artradol activates regenerative processes in the cartilage surfaces of the joints, resulting in the production of normal joint fluid, do not allow the collapse of the connective tissue. Because of this level of exposure decreases pain, improves joint mobility.
In view of the structural similarity with Heparin drug can potentially prevent the emergence of fibrin clots in the subchondral and synovial microvasculature.
Pharmacodynamics and pharmacokinetics
Absorption and distribution of chondroitin sulphate when administered intramuscularly occurs easily. Half an hour after administration, the preparation can already be detected in the blood at high concentrations, 15 minutes later the drug found in the synovial fluid. The maximum concentration observed one hour after administration over two days of active substances gradually decreases. Artradol mainly accumulates in the cartilage.
The drug is eliminated via the kidneys during one day.
Indications
Injections Artradola appointed the following diseases:
- Primary arthrosis ;
- degenerative dystrophic diseases of the spine, joints;
- osteoarthritis That affects large joints;
- intervertebral osteochondrosis .
Contraindications
It does not apply in the following cases:
- high sensitivity to its components;
- children age of the patient.
Very carefully appointed means people who are prone to bleeding; patients thrombophlebitis ; during pregnancy and lactation.
Side effects
In applying the drug is rarely observed these side effects:
- allergic reactions;
- hemorrhage in the place where the injection is carried out.
Instructions for use (method and dosage)
Instructions on Artradol following: injections administered to patients by intramuscular injection, is administered every other day 100mg. If the tool is well tolerated, after the third injection, the dose may be increased to 200 mg. Total for the treatment appointed from 25 to 35 injections. Repeat the course of therapy can be six months. How much time should last a second course of therapy, determined by a physician in each individual case.
Application Instruction Artradola provides that immediately before the introduction of the contents of the ampoule is to be dissolved in 1 ml of water for injection.
Overdose
There are no data on overdose means.
Cooperation
If Artradol taken simultaneously with indirect antiplatelet . anticoagulants . fibrinolytics Can amplify the impact of these drugs on the body. In this case it is necessary to monitor the performance of blood clotting.
Terms of sale
Sold by prescription.
Storage conditions
Keep Artradol should be in a dark place, and the temperature should not exceed 25 ° C. We need to protect children from the vehicle.
Shelf life
Store medicines can be 3 years.
Analogs Artradola
Glucosamine Chondroitin-
Glucosamine
Glucosamine hydrochloride
Glucosamine Maximum
Nutrilite Glucosamine
Nimid Forte
Nimid
Struktum
Hondrogard
Kartilag Vitrum
Mukosat
Glucosamine sulfate
Nimesulide
Chondroitin sulfate
Nimulid
Nimesil
Drugs that contain similar active ingredient, are analogues of the drug, but they can still act on the body a little differently. Therefore, independently, without prior consultation with a doctor should not be anything to replace Artradol. However, in the pharmacy network realized a lot of money - chondroprotectors , Which also contains chondroitin sulphate, for example, Hondrolon . Honsurid . Alflutop et al. Price analogues is essentially higher.
Babies
For the treatment of children is not applicable, because there are not enough clinical data on its impact.
During pregnancy and lactation
Pregnant women and nursing mothers means used with caution.
Reviews Artradole
The forums reviews Artradole occur relatively frequently. In particular, patients with illnesses of the spine reviews and al. Suggest that the injections significantly reduced pain as early as during the first course of therapy. According to patients, the drug is effective in reducing edema in patients with osteochondrosis, arthrosis. Positive reviews in the ground and doctors, which states that the drug affects the most effective, if used strictly according to the scheme, and in a dose that is assigned to a specialist.
The feedback is very rarely mentioned about the side effects means. Sometimes people who have undergone drug treatment, mention minor allergic reactions, as well as the emergence of hemorrhage in places where the injection is carried out.
Price Artradola where to buy
Price injections Artradola in Russia is on average from 720 to 850 rubles (package of 10 pcs.). In other cities the price of a medicine may be slightly different. For example, buy the drug can be in Moscow for about 700 rubles. (10 pcs.). Price Artradola in Ukraine is about 500 - 620 hryvnia for 10 vials. Ointment Artradol costs about 100 rubles. Tablets Artradol not released. Belarus vehicle is not registered, so buy the drug in Minsk only by reservation.
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