Semaks

Description overdue on 14.10.2011

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The main active ingredient - Semaks It refers to the group nootropics . Original drug has effects on the central nervous system neuron. Even small doses of drugs have a pronounced effect neurometabolic. The drug in high doses has angioprotective . antihypoxia . antioxidant   and neyrotrofichekoe   impact. Semaks penetrates the BBB after 4 minutes after the nasal administration, the therapeutic effect lasts for hours. The drug stimulates the processes responsible for learning, memory, improves the body's adaptation to the Cerebral ischemia . hypoxia . anesthesia . Drug increases activity acetylcholinesterase . Deprivation of oxygen and glucose by the action of the drug have trophotropic impact .

The drug directly affects the molecular triggers, normalizes blood Cytokine Increases the concentration of anti-inflammatory factor reduces the formation nitric oxide It inhibits lipid peroxidation, decreases the level of cyclic guazinmonofosfarta . The drug has a positive effect on adaptation to hypoxia, suppresses postgiperventilyatsionnye EEG effects due to a decrease in cerebral blood flow. With a single, long-term administration of the drug does not have toxic . teratogenicity . embriotoksicski . mutagenic   effects, does not cause allergy. It does not have a local irritating action.

Dosage Form:

Nasal drops.

Indications:

Semax is used for intellectual-mental disorders Caused by vascular lesions of brain tissue after traumatic brain injury ( traumatic brain injury ), Anesthesia, neurosurgery At vascular encephalopathy , Circulatory disorders and blood circulation of the brain after exposure to ionizing radiation at neurotic disorders . The drug is effective after stroke It increases the body's adaptation to extreme situations. Drugs used as prevention of mental overstrain   during a stressful work, monotonous work.

Semaks effective in treating attention deficit syndrome with hyperactivity syndrome, cerebral dysfunction in children of 5 years. At a concentration of 1% formulation used in the acute phase after an ischemic insult. In oftalnomologii: optic atrophy . inflammatory . toxic-allergic neuritis .

Contraindications:

Acute psychosis, convulsions, pregnancy, lactation.

Side effect:

Prolonged use may result in irritation of the mucous membrane in the nasal cavity. There insomnia , Irritability.

Mode of application:

Intranasal administration. In one droplet contains 50 micrograms of the basic substance. Using a pipette 2-3 cap. the solution is introduced into each nostril. In some cases, the dose is increased, the interval between doses is 10-15 minutes. Single dose - up to 2000 mg. At night no more than 5000 mcg. Semax is used day 3-5 days. In some cases, treatment may be extended for up to 2 weeks. In diseases of the optic nerve: a day not more than 900 mg, 2-3 cap. 3 times a day for a week. Children: 2 drops twice a day (a course - 1 month). At night no more than 400 micrograms.

Overdose:

Even if the dose is significantly exceeded overdose cases were not recorded.

Drug Interactions:

The drug is rapidly destroyed in the gastrointestinal tract is not received, excluding drug interactions with most drugs. Not recommended simultaneous reception of medicines, providing local vasoconstrictor effect (given the intranasal administration of the drug Semax).