Aurobin

Description overdue on 10/26/2014

• Latin name: Aurobin
• ATC code: D07XA02
• Active substance: Dexpanthenol + Prednisone + Lidocaine
• Manufacturer: Gedeon Richter of Hungary

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Ointment Aurobin, instructions for use
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

1 g of ointment contains the following active ingredients:

• 0, 002 g - Prednisolone capronate;
• 0, 020 g - Lidocaine hydrochloride;
• 0, 020 g - Dexpanthenol.

Additional ingredients:

• 0, 001 g - triclosan;
• 0, 001 g - polysorbate 60;
• 0, 002 g - methyl parahydroxybenzoate;
• 0, 01 g - cetyl alcohol;
• 0, 02 g - propylene glycol;
• 0, 05 g - liquid paraffin ;
• 0, 05 g - macrogol stearate;
• 0, 05 g - dimethicone;
• 0, 08 g - stearic acid;
• 0, 06 g - neutral oil;
• 0, 62 g - purified water.

Product form

One pack contains 1 aluminum tube, comprising 20 g of ointment.

Pharmacological action

Antiseptic, anti-allergic, regenerating, antiexudative, local anesthetic, anti-inflammatory, analgesic.

Pharmacodynamics and pharmacokinetics

Aurobin Ointment is a combination drug, have pharmacological actions that are typical of its active components. Lidocaine .   Dexpanthenol   and Prednisolone   mutually compatible and actively complement each other's effects, thereby effectively reducing the symptoms of disease states perianal region and rectum.

Lidocaine Being Quite quickly and efficiently eliminates itching and   pain symptoms Caused by diseases of the skin and inflammation of the perianal area.

Prednisolone - Drug group glucocorticosteroids (non-halogenated) It has the ability to diminish the amount   , Reduce   exudation phenomenon, the permeability of the vessel walls and itching different etiology.

Dexpanthenol   refers to B vitamins   and metabolism in tissues susceptible to pantothenic acid,   activates the regeneration of tissues, reduces the time of healing of skin lesions.

When applied topically, a small part of prednisolone and lidocaine is absorbed into the systemic circulation. This lidocaine is bound to plasma proteins, lends itself metabolized in the liver and mostly excreted by the kidneys, it penetrates the blood-brain barrier. T1 / 2 - 1-2 hours.

Prednisolone is rapidly spreading in the body passes through the blood-brain barrier, excreted in urine in the form of conjugates.

Indications

•   or   eczema;
• itching anus;
• hemorrhoids;
• anal fissures;
• fistula of the anus;
• other inflammatory perianal area.

Contraindications

• Skin infections   fungal, bacterial and viral etiology;
• parallel to the initial treatment with drugs containing Lidocaine;
• age of the patient up to 1 year;
• first trimester   pregnancy;
• hypersensitivity to the active and auxiliary ingredients of the formulation;
• Aurobin should not be applied to the periorbital area   and used for the treatment of eye .

Side effects

Glucocorticoids for external application, first of all, can lead to adverse effects of local character: burning sensation, worsening of tightening damage, irritation, thinning of the skin, dryness, sensitivity   skin.

When long-term therapy possible skin atrophy, telangiectasia, a local hirsutism, purple, hypertrichosis, hypopigmentation, folliculitis, fungal infections, acneform rash, diaper rash, allergic contact dermatitis.

In applying Aurobin over a large surface (or in large quantities) systemic reactions observed side effects of glucocorticoids   (Cushing's syndrome, growth retardation, increased intracranial pressure   at the end of therapy,   glycosuria, hyperglycemia, increased blood pressure, hypokalemia).

Long term treatment, especially in large doses, can cause bradycardia due to systemic effects of lidocaine.

Ointment Aurobin, instructions for use

Instructions on Aurobin involves the use of an ointment only topically and rectally.

Patients in the adult and the elderly is recommended 2 - 3 times a day application of ointment on the damaged surface, per day.

When an internal arrangement hemorrhoids   a small amount of the substance of ointment administered directly into the rectum. 2-4 perform the application of the day. By reducing the symptoms can reduce the number of procedures. The course of treatment usually takes 5-7 days.

Selecting the treatment regimen and selection of doses Aurobin in children (older than 1 year) is carried out individually.

Overdose

When used incorrectly Aurobin or chronic overdose may experience negative symptoms associated with systemic corticosteroids, as well as due to Lidocaine - bradycardia.

Cooperation

No reliable information on drug interactions Aurobin, when applied topically.

Terms of sale

Prescription.

Storage conditions

At a temperature of 8 to 15 ° C.

Shelf life

24 months.

Cautions

Do not recommend the use of an ointment Aurobin for a long time, especially in children, due to possible adrenal suppression.

Avoid contact with the drug on the periorbital region and eyes. In case of accidental contact with skin should be washed with water.

The development of secondary infection, as well as its distribution, are a cause for discontinuation of therapy and administration of appropriate antifungal or antimicrobial therapy .

Before applying the ointment is recommended to thoroughly clean and dry for the alleged treatment of skin, as wet conditions predispose to bacterial infections.

Aurobin Drawing on extensive areas or use it for a long time can cause systemic absorption of the active ingredients that contribute to the development of atrophy of the skin, especially in patients at a young age.

Analogs

• Anuzol;
• Betiol;
• Procto-Glivenol;
• Sulfodekortem.

Babies

Aurobin drug in children can only be used with a 1-year, and with extreme caution. Selected minimum effective dose for the duration of therapy does not exceed 5 days.

During pregnancy (and lactation)

Do not set the first trimester of pregnancy and with extreme caution (the potential risk / benefit to the fetus) in the second and third trimester.

Due to the penetration of lidocaine and prednisolone in mother's milk, it is best to stop lactation .

Reviews Aurobin

Many people suffering from hemorrhoidal disease states, as well as other inflammatory problems in the perianal region are looking for an effective hemorrhoid ointment. Reviews on Aurobin appointed precisely to address these problems in the treatment of hemorrhoids third and fourth stage, mostly cheers and noted the effectiveness of therapy, removal of pain, faster healing of anal fissures.

Also, there is no unequivocal opinion on the advisability of Aurobin for external hemorrhoids.

From all this we can conclude that before buying and applying a drug, it is better to consult a medical specialist whose opinion you trust.

Price Aurobin where to buy

When choosing a medicament for the treatment of hemorrhoids is necessary to pay attention not only to the efficiency and cost of the drug, but also its pharmacological form. A qualified doctor will recommend a cream, candles, ointment or rectal capsules.

Price ointment Aurobin pharmacies Russia ranges from 200 rubles.

Price ointment in Ukraine 70 hryvnia.

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