Calcium gluconate

Description overdue on 12-12-2011

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Regulator calcium-phosphorus metabolism . Effect of the drug is aimed at filling the deficit Ca2 + in the body. Calcium is involved in bone formation, contraction of smooth muscle, skeletal muscle, nerve impulse transmission, blood coagulation . In the intercellular bone substance is a huge amount of calcium, which, together with protein Collagen   It provides flexibility and hardness of the bone. Calcium gluconate has dezintoksikatsonnym, anti-allergic, anti-inflammatory, hemostatic influence, prevents fragility of blood vessels, reduces the permeability of vascular wall. Is a crystalline or granular powder is white, has no specific taste, odorless. Cold water dissolves slowly in ether and practically insoluble ethanol. Calcium gluconate contains 9% calcium. Produced in tablet form, as a solution for intramuscular, intravenous injection.

Indications:

Calcium gluconate is prescribed for diseases involving hypocalcemia , In violation of neuromuscular impulses , Increased vascular permeability. The drug is effective in osteoporosis . hypoparathyroidism . rickets . osteomalacia , Spazmofilii, renal failure, hyperphosphatemia in the system at the stage of chronicity. Calcium gluconate is shown when taking diuretics, allergies, fever syndrome, serum sickness . angioedema , Pulmonary tuberculosis . eclampsia , Lead colic, poisoning salts of magnesium, fluoride acid, oxalic acid. The drug is used in the periodic paralysis   (giperkaliemicheskaya current form), nephritis, toxic liver system, parenchymal hepatitis.

Contraindications:

Calcium gluconate is not prescribed for calcium nefrourolitiaze Expressed hypercalciuria , Hypercalcemia, hypersensitivity receiving cardiac glycosides, in sarcoidosis. Diarrhea, electrolyte disturbances, dehydration, widespread atherosclerosis, low hypercalciuria, malabsorption syndrome , Hypercoagulable drug is prescribed with caution. Because of the risk of necrosis of the children is not recommended to conduct an intramuscular injection.

Side effect:

Receiving tablet form   the drug causes irritation of the digestive tract, constipation . After injection notes bradycardia , Diarrhea, dyspepsia. Intravenous   the drug is accompanied by a sensation of heat, burning sensation in the mouth. With the rapid intravenous injection of conduct marked drop in blood pressure, heart failure, syncope, arrhythmia. Intramuscular   can lead to the development of necrosis at the injection site. If overdose is recommended introduction of calcitonin + NaCl for 6 hours (5-10ME / kg).

Mode of application:

Tablet form taken for 1, 5 hours before eating, it is recommended to wash down with milk. Dosage: 1-3 grams three times a day. Intravenous injection is carried out slowly, dropwise 10% solution in an amount of 5-10ml every other day.

Special instructions:

When nefrourolitiaze, reduced glomerular filtration rate , Hypercalciuria use of the drug is carried out under the control of the level of calcium in the urine. Drinking plenty of fluids to prevent nefrourolitiaz.

Drug Interactions:

Calcium gluconate is incompatible with sulfates, salicylates, carbonates . FROM tetracycline antibiotics   forms insoluble complexes. Concomitant use with quinidine   It leads to retardation intraventricular conduction It increases toxicity of quinidine. Calcium gluconate reinforces the effect of cardiotonic glycosides. The drug reduces the absorption rate of iron supplementation, Digoxin , Tetracyclines. The drug reduces the bioavailability   phenytoin Reduces effektinost calcitonin in the treatment of hypercalcemia, increases the level of calcium in combination with thiazide diuretics .