Ernits

Description overdue on 09/09/2014

• Latin name: Erynit
• ATC code: C01DA05
• Active substance: Pentaerythritol tetranitrate (Pentaerithrityl tetranitrate)
• Manufacturer: LLC "Farmapol-Volga", Russia

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications erinita
• Contraindications
• Side effects
• Instructions for use erinita (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The tablets are composed of active substance Ernits And optional ingredients: dextrose , Potato starch, talc, stearic acid, sugar.

Product form

The tool is available as tablets for 0, 01 and 0, 002, they are white with marble shade, a lenticular shape. In blisters of 10 tablets fit. In a cardboard box packed by 1 or 5 contour packs.

Pharmacological action

On the body acts as a koronarorasshiryayuschee means Under its influence vessels dilate heart. The drug is venous vasodilator provides antianginal effect. After administration are stimulated nitric oxide production in the vascular wall. Nitric oxide, in turn, is endothelium-derived relaxing factor. Ernits   reduces preload and afterload on the heart. After treatment with a marked decrease in myocardial oxygen demand.

During exposure erinita restored blood flow through small vessels endocardial. As blood flow becomes more active in the epicardial coronary arteries. Ernits   increases tolerance to stress of a physical nature in people who suffer coronary heart disease . angina .

People who suffer from heart failure, the drug provides unloading of the myocardium, reducing preload. Also, when the treatment tool is lowered the pressure in the pulmonary circulation.

Pharmacodynamics and pharmacokinetics

Compared with the influence on the organism nitroglycerin Then Ernits acts more slowly, but provides a long-lasting effect, which lasts up to 10 hours.

After oral effect observed after approximately 30-45 minutes. If the pills are taken sublingually , The action begins in 15-20 minutes. The period of the drug is on average 4-5 hours. Mucosa means absorbed relatively slowly.

Indications erinita

The Regulations provide for the following indications for use erinita:

• coronary insufficiency   chronic type (if you do not meet the need of the heart in the amount of oxygen and its delivery to the blood through the arteries of the heart);
• coronary artery disease ;
• angina (also as prophylaxis, including after infarction);
• chronic heart failure   (As part of an integrated treatment).

Contraindications

Before taking this medication, the doctor should clearly explain to the person from which tablets Erin and determine no contraindications or the patient. Contraindications to the treatment of the following means:

• high intracranial pressure ;
• hypotension (reduced arterial pressure );
• closure glaucoma   (intraocular pressure);
• high sensitivity to this facility to other organic nitrates;
• shock, collapse;
• sharp myocardial infarction In which marked orthostatic hypotension;
• state after traumatic brain injury;
• cerebrovascular accidents (especially after a hemorrhagic stroke );
• pregnancy   and feeding ;
• children and adolescents under 18 years of age.

Do not take the tablets at the same time with the PDE.

Side effects

Can show such side effects while taking this drug:

• noise in ears;
• dizziness   and headache;
• allergic reactions ;
• nausea, intestinal upset;
• a high level of fatigue and weakness;
• tachycardia ;
• heavy sweating ;
• a manifestation of anxiety;
• decrease in blood pressure.

Instructions for use erinita (method and dosage)

If the patient is going to take pills Erin application instructions must be followed exactly to them. Tablets to be taken orally, one hour before a meal, wherein the daily dose is 20 mg, which is divided into three or four portions. If there is such a need, it is possible to increase the dose to 40 mg, while it should be divided into four stages. It is also possible to increase the dose up to 80 mg, which is to be divided into two stages.

If there is such a need, perhaps Sublingual   facilities. If reception erinita combined with beta-blockers and the BCCI, the doctor may prescribe a single dose of the drug. It needs to be taken at the time of day when most concerned about patient symptoms of angina.

Duration of therapy is usually 2 to 4 weeks, repeated treatment may designate the treating specialist.

Overdose

If an overdose of the funds may experience the phenomena described as side effects. In this case you need to carry out an urgent gastric lavage, take Activated carbon . Apply symptomatic therapy.

Cooperation

If the patient is receiving erinita take any other drugs, it is necessary to be sure to inform your doctor.

Dihydroergotamine   It can significantly reduce the antianginal effect erinita, therefore this combination should be considered irrational.

Propranolol   increases antianginal effects erinita, so this combination is considered to be rational.

Terms of sale

In pharmacies pills are sold only by prescription.

Storage conditions

It is necessary to protect the tablets from moisture and light, the air temperature should then be 12-15 ° C. Ernits should be protected from access by children.

Shelf life

Shelf life - 3 years.

Cautions

Do not take the pills in order to eliminate manifestations angina Since its effect is too slow.

If the treatment lasts longer due, it may decrease the effectiveness of drugs due to the manifestation of tolerance. To reduce the risk of manifestation of tolerance, you need to refrain from taking nitrates for 8-12 hours.

If Ernits taken once daily while combined with other antianginal drugs, reduced the likelihood of developing tolerance.

A higher probability of hypotension observed in people with dehydrated body, the elderly.

Since the treatment of this agent may develop drowsiness . dizziness . severe fatigue .   blurred vision , Drive trucks and do chores that require maximum accuracy, it is not recommended.

Analogs erinita

Match code ATC 4th level:

• Izoket
• Kardiket
• Fort sustaka
• Nitrosorbid
• Nitroglycerine

The following analogues erinita: drugs Pentral . Pentaeritriltetrat . Nitropentor . Pentafin . Pentalong . Pentaril . Neo-Korovaz . Pentanitrin . PETN . Perangil . Peritrat . Vazodilatol . Kvintrat . Nitrinal . Vazokor . Nitropentrit .

The decision to accept the replacement of a doctor.

Babies

Not used for the treatment of children and adolescents under 18 years of age, as there is no sufficient information about the safety of such therapy.

With alcohol

Influenced ethanol   erinita enhanced effect. It should completely eliminate alcohol intake during treatment.

During pregnancy and lactation

Do not use this tool for the treatment of mothers and lactating women.

Reviews of Erin

The network has various reviews Erin, which indicate how its effectiveness and the lack of expected action.

There are also some patients, information that triggered tablets manifestation of side effects, in particular, chronic headaches, reduced pressure. In this case, people turned to the doctor who was looking for a replacement for this facility.

Price erinita where to buy

Erinita price depends on the number of tablets in the package. Buy tablets (50 pcs., 10 mg) can be an average of 60 rubles.

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