Simethicone

Description overdue on 01/08/2014

• Latin name: Simethicone
• ATC code: A02DA
• Active substance: Simethicone (Simethicone)
• Manufacturer: Ratiopharm GmbH., Germany

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Simethicone: instructions for use, dosage regimen
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Newborns
• Reviews
• Price, where to buy

Composition

Simethicone - is an organic compound whose molecules indicated a link between silicon and carbon atoms. It has the form of a viscous gray translucent liquid, which contains from 4 to 7% microfine silkona dioxide. It is characterized by the inability to dissolve in water and alcohol.

Product form

The drug comes in the form of:

• capsules ;
• emulsion ;
• drops   oral;
• suspension ;
• masticatory tablets .

Pharmacological action

Simethicone has carminative and defoaming properties, and its effect is to reduce the foam and gas formation in stomach   and intestine . The substance is inert, non-toxic and can be surface activity.

Physically reducing the surface tension, it promotes elimination of the gas bubbles which are formed in the intestinal tract in flatulence . Thus liberated gas is absorbed and / or completely removed from the body naturally, without causing any discomfort to the person.

Also, the drug prevents the further formation of new gas bubbles. A similar effect is provided due to the ability of a substance to reduce the surface tension arising at the interface of two different phases.

Pharmacodynamics and pharmacokinetics

Preparations simethicone improve irrigation of the mucous membranes gastrointestinal tract   contrast agents, thereby preventing the occurrence of fractures in contrast film.

Simethicone-containing medicines do not irritate the mucous membrane gastrointestinal tract Not provoke changes in clinical endoscopic picture and do not affect the motility and evacuation function of the stomach and intestines.

The substance is considered to be completely safe for patients, and has no negative effect on the equipment used for medical and medical-surgical endoscopic procedures.

Against the background of the abuse of food, which contains a large number of carbohydrates   at stomach   and gastrointestinal tract   there is an increase flatulence , Which in turn stimulates intestinal lumen clogging undigested protein substrates forming the dispersion of liquid and gas bubbles. This system is entirely subject to the laws of surface tension.

As a result of violations digestive processes   deteriorating the absorption of nutritional components enhanced gas and foaming. Because of this:

• deteriorating normal pristennyh digestion ;
• decreases enzyme activity ;
• decreases reabsorption of gases .

Against the background of simethicone:

• decreases in the severity of gassing gastrointestinal tract ;
• decreases in the severity of pain epigastric Which are caused by accumulation of gases gut   or impaired digestive function ;
• improves overall health when flatulence .

Once in the body, it is poorly absorbed in the Simethicone gastrointestinal tract   and excreted from the body unchanged.

Indications

Simethicone advisable to appoint:

• patients suffering from symptoms flatulence   (including flatulence Which is celebrated after   surgery );
• at aerofagii   (pathological condition that is manifested by increased air ingestion during meals);
• patients diagnosed with   gastrocardiac syndrome   ( Remhelda syndrome );
• in the preparation of the patient for the procedure radiography ;
• in the preparation of the patient for Sonography ;
• in the preparation of the patient for endoscopic manipulation ;
• in preparing the patient for the procedure ultrasound diagnostics .
• Poisoning with surfactants;

Contraindications

Instructions drug warns that such a substance as simethicone is contraindicated for people who have an increased sensitivity to it, as well as patients suffering from bowel obstruction   and obstructive diseases   digestive system.

Side effects

In some cases, the drug Simethicone may be accompanied by side effects which can be expressed as allergic reactions .

Simethicone: instructions for use, dosage regimen

The drug is available in several dosage forms and different concentrations. For this reason, the optimum dose of simethicone in each case must be determined by a physician, which is repelled by the age of the patient and the severity and nature of the disease.

The drug is taken orally after a meal or a meal at the same time, optimally - before going to bed. Babies simethicone is mixed with food or liquid. The duration of treatment may vary depending on the treating physician.

For adult patients a dose of simethicone suspension   from 25 to 50 drops. Before each use, suspension   bottle it is advised to shake. Capsules   it is recommended to take one or two pieces, swallowing whole. Wash down the drug liquid is not necessary.

In accordance with the instructions for use of simethicone school-age children is prescribed to take 15-20 drops of the drug in the form of suspension And pre-school children and newborn babies - 10-15 drops.

Before the procedure, study intestinal tube   recommended daily dose is from 6 to 8 capsules of 150 or 200 drops slurry. The preparation is recommended to begin two days before the study. On the day of study morning fasting take two capsules or drug 50 in the form of drops suspension . A similar dose and should be taken immediately before the procedure.

Patients with signs intoxication   surfactants prescribed take from 20 to 25 ml of suspension.

Overdose

Since the systemic absorption of the drug is described as extremely low, simethicone classified as safe drugs. However, if you accidentally exceeding the recommended dose should consult your doctor.

Cooperation

The drug should not be simultaneously combined with antacid drugs Whose mechanism of action is based on the chemical neutralization increased acidity of gastric juice .

Terms of sale

The drug is available without a prescription.

Storage conditions

Simethicone as suspension   and capsules   stored at a temperature not exceeding 30 degrees Celsius. After opening the bottle with the drug suspension is allowed to store no more than one month.

The suspension   It is not subject to freezing.

Shelf life

The product is usable for 3 years.

Analogs simethicone

Analogues of drugs are medicines created on its basis:

• Bobotik ;
• Espumizan ;
• Sab Simplex ;
• Disflatil ;
• Meteospazmil ;
• Pepfiz ;
• Simikol ;
• Alverin ;
• Kolikid ;
• Infacol .

Simethicone for newborns

Simethicone due to its safety and low absorption   gastrointestinal tract   It may be used to assign to young children. It is also suitable for newborn babies. The optimal dosage form is drops   or suspension .

Before use, the vial was shaken, after which the dose necessary mixed with human milk or water. A single dose should not exceed 50 mg of active substance. The allowable number of doses throughout the day - 5.

The drug is allowed to be used for a long period of time, up to several weeks.

Reviews of simethicone

Numerous comments left by mothers of infants in the forums suggest that simethicone effectively eliminates unpleasant phenomena such as cramps   babies. Many mothers also noted that the drug worked well in cases where children often vomit after eating.

Price simethicone

Simethicone is the active substance of a large number antigas medicaments. Drug itself rarely found in drug stores, unlike preparations in which it is included as an active ingredient.

Depending on the country and the pharmaceutical company producer price simethicone-containing agents can range from 175 (capsules Espumizan   produced by Berlin-Chemie, Germany) to 400 Russian rubles (about the same amount of the drug purchase costs Meteospazmil   Laboratory Majoli Spindler, France, which is available in capsule form).

Buy Simethicone can be without a prescription. The drug and its analogues are released in the majority of pharmacies and pharmacy chains.

Before purchase and use of simethicone for infants should consult with the attending physician of the child.

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