Description overdue on 10/30/2014
- Latin name: Duphalac
- ATC code: A06AD11
- Active substance: Lactulose (Lactulose)
- Manufacturer: Abbott Healthcare Products B.V. (Netherlands)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Duphalac Syrup, instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Dufalac children
- Newborns
- Slimming
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition Duphalac
Composition 100 ml syrup:
- lactulose - 66 7 g;
- Purified water to 100 ml.
Product form
The pharmacy is sold as a medicine Syrup in plastic bottles of 200, 500 and 1000 ml with a special screw cap. In a cardboard box, in addition to the pharmaceutical preparation is placed a measuring cup. Also laxative can be found in disposable plastic bags of aluminum foil designed for 15 ml. Packaging usually contains 10 bags.
Pharmacological action
Duphalac Syrup classified in the medical literature as the theme laxative medicine. The drug has hyperosmotic action stimulates the physiological act of intestinal peristalsis, improves absorption calcium salts and phosphates. Also, the influence of the drug apply to the syrup nitrogen metabolism - The migration of ammonia from the blood into the intestines, where the largely reduced the formation of toxic products of metabolism of nitrogen and inhibited their absorption in the inferior vena cava.
The mechanism of the therapeutic effects of the pharmaceutical preparation is in the active co-operation of the active ingredient with the natural microflora of the large intestine. Properties allow an increase in the amount of lactulose lactobacilli Which at its cleavage to form low molecular weight acids reducing acidity in the lumen of the digestive tube. The result of this cooperation is to reduce the osmotic pressure and an increase in intestinal contents, which appears to stimulate peristalsis and the changing nature of the chair.
Pharmacodynamics and pharmacokinetics
Laxative use orally . Absorption of the active ingredient in the digestive tract is low. After oral administration the drug virtually unchanged reaches the large intestine, where splits natural microflora inhabiting the lumen. Full metabolization pharmaceutical preparation is in a dose of about 45-70 ml (the exact number depends on the individual metabolic processes of speed). If the dosage exceeds a certain number can be found in the secretions unchanged.
Indications
- severe chronic costiveness (constipation);
- regulation of physiological rhythm emptying the colon;
- softening stool at hemorrhoids or upcoming operations in the final parts of the gastrointestinal tract;
- hepatic encephalopathy ;
- putrid dyspepsia syndrome children younger age category;
- hepatic coma prekomatosnoe and state;
- dysbiosis kishechnika.yu caused by the persistence of Salmonella, Shigella.
Contraindications
Contraindications to the use of the drug include:
- Increased individual sensitivity to the constituent components of the pharmaceutical formulation;
- inherited or acquired intolerance active ingredient;
- rectal bleeding hemorrhoidal genesis;
- galactosemia ;
- colostomy and ileostomy;
- ileus of different origin;
- suspicion of acute Appendicitis ;
- diabetes (endocrine pathology is not considered an absolute contraindication for the use of a medicinal syrup, but apply it to the background of this disease should be under the control of trained professionals).
Side effects
Laxative Duphalac in the first days of the course of conservative treatment can cause sluggish manifesting abdominal distention and flatulence Which resolved on their own for two days. Also there may be abdominal pain, nausea . vomiting . diarrhea , Electrolyte imbalance, as a result - with udorogi, arrhythmia, myalgia, excessive fatigue, headache, vertigo e and weakness . If the adverse effects of therapy pharmaceutical preparation is not excluded from the rehabilitation scheme, but only in a certain way adjust its dosage.
Duphalac Syrup, instructions for use (method and dosage)
Laxative intended for oral internal administration. The drug solution can be used in diluted or undiluted. All you need to take a single dose in one gulp without delaying the syrup in the mouth.
Instructions for use Duphalac
The main purpose of the appointment of pharmacological agents - softening stool and treatment of constipation . To this syrup should be taken at the same time throughout the conservative course. It is also recommended drink plenty of fluids in process - 1, 5-2 liters per day. Driving therapeutic doses depends largely on the age category (initial dosage is supported):
- adults and teenagers - 15-45 ml;
- children 7-14 years - 15 ml;
- children 1-6 years, 5-10 ml;
- children under 1 year - up to 5 ml.
How many acts of pharmacological agents, unequivocally answer is virtually impossible because of the individual peculiarities of metabolism Each of the human body, however, as a rule, the therapeutic effects of constipation are not forced to wait long and prominent on the second day of the course of conservative treatment.
How to take a newborn?
Immediately after birth or in the early childhood mothers often face the problem of constipation in children, because their digestive systems are not adapted Power to such a character. Also on site microorganisms gastrointestinal tract has not yet developed sufficiently to provide a normal process speed Fermentation products . Because newborns often prescribed Duphalac.
Dosages pharmaceutical preparation selected from the subjective feelings of the child after his admission. Typically, the amount of the syrup ranges from 1 to 5 ml. Bred laxative in water or breast milk. Giving a drug better right after a night's sleep or the first morning feeding, but with the rapid regurgitation should be repeated manipulation. Interestingly, the "children's" therapeutic effect occurs within a few hours.
How to take Duphalac in the treatment of coma and precoma pechenchnoy?
Initial dosage of the drug is 30-45 ml syrup 3 times a day. Further dose picked individually - in order to avoid the adverse effects of treatment, and drug overdose. The criteria for correctly chosen amount of syrup They are:
- soft stool 2-3 times a day;
- colon acidity within 5, 0-5, 5;
- no abdominal pain or other side effects.
Separately, it should be noted how long effects of drugs, because Metabolic Effects biologically active components can not be developed simultaneously. When hepatic pathologies, such as therapeutic effect on the passage Duphalac markedly 2-5 days, depending on the individual's metabolic rate.
Instructions for use in the treatment of dysbiosis Duphalac digestive tube
In the treatment of disorders of quantitative and qualitative composition of the natural microflora of the large intestine pharmacological drug is not used as a laxative, as well as a full probiotic Because the main purpose of his appointment is to increase the fraction of lactic acid bacteria and changing the acidity of the internal environment to inhibit the growth of pathological microflora. When dysbacteriosis the following Dosage drug syrup:
- children under 1 year - 1, 5-3 ml;
- the age group of 1 to 3 years - 3 ml;
- preschoolers from 4 to 7 years - 5 ml;
- school age and adults - 10 ml.
Overdose
Use of excessive amounts of the drug can lead to the pathological state of an overdose, which is characterized by such symptoms as stomach ache . diarrhea . electrolyte imbalance . In the case of such consequences of conservative treatment method of application and the dosage should be reduced after consultation with a qualified health care professional.
Cooperation
Combined use of Duphalac with antacid drugs and some antibiotics reduce its therapeutic effectiveness.
Mode of action of lactulose, the active ingredient of the drug, accompanied by low acidity content of the large intestine, and accordingly changes the release pH-dependent active ingredients For example, in the treatment of drug 5-aminosalicylic acid .
Terms of sale
Buy a laxative can be without presenting the corresponding form of the receptor.
Storage conditions
Annotation to prescribe a drug store it in a place protected from direct sunlight, out of reach for children of all ages at a constant temperature range of 10 to 25 degrees Celsius.
Shelf life
3 years
Cautions
In addition to traditional therapeutic treatment Dufalac also actively used Veterinary Practice As in structure gastrointestinal tract of most mammals is virtually identical to one another. Thus, for example, can often find this purpose laxative for cats Because these are extremely neat pets swallow some amount of hair that accumulates in the lumen of the colon and lead to difficulties with defecation. It is also common problems with diets favorites.
On veterinary forums often heard questions addiction cats to different drugs, because such a tendency at this kind of pets, unfortunately, there is and has been repeatedly ridiculed in jokes and parables. What about Duphalac - is whether the addictive drug is difficult to answer. Cats do not start asking for more laxatives, however, have to use it regularly, because the animal is weaned from the "washing" it is impossible, because some vets have theorized about a fairly constant consumption, which makes the addictive imperceptible.
How to take for constipation in cats?
Dosage Cat is 0, 5-2 ml per animal of medium size. The amount of drug syrup and you can pick up on their own, guided by calculation of 0, 5 ml per 1 kilogram pet. Giving the pharmaceutical formulation should be mealtime Because the syrup has a distinctive sweet taste that can be quite like a cat or a cat.
How many takes effect?
Of special note is that the therapeutic effects in pets have constipation develop much faster than humans. Active effect of the pharmaceutical preparation can be observed within a few hours after taking the syrup.
Analogs Duphalac
Normase
Forlaks
Fortrans
Dufalac refers to not the cheapest pharmaceuticals because usually analogs cheaper in price. So replace the therapeutic effect can be a laxative syrup pharmacy products as Good luck , Crystalline Lactulose . Legendal or Lizalak .
Blow away, of course, noted the Russian equivalent of Duphalac Lactusan As the basis for the therapeutic properties of laxative is already familiar lactulose, and the cost of the drug is much lower in local pharmacy, as the drug is produced in Russia. In addition to the prices differ and indications for use Lactusan because pharmaceuticals They are not completely interchangeable in all cases. In each situation, you should consult with your doctor whether it is possible to choose a laxative that is not so much an effort on the pocket.
Another good analog drug is considered made in Italy Normase - It is the osmotic laxative action, which is a synthetic polysaccharide. It has an identical mechanism of action and the same indications for use, because once the question arises - it is better to Normase or Dufalac ? Amongst side effects Normase marked Longer nausea, flatulence, bloating and even colic. Also, there may be skin rashes, but the cost of the drug is somewhat lower than the price of Duphalac, both in Ukraine and in the Russian Federation, because to answer this question will each individually.
Dufalac children
Duphalac is actively used in pediatric patients Starting with the youngest age group, because the problems with emptying, unfortunately, not uncommon in the daily work of a pediatrician. By the time of birth of children's gastrointestinal tract is not yet fully completed its development is virtually clean of beneficial microflora of the digestive tube - a major cause of constipation. Instructions for children in the pharmaceutical preparation only fundamentally different dosages used in the conservative treatment.
Since the drug is often used for children, opinions about Duphalac overwhelmed thematic forums and websites. Most of them are positive, because the medicinal syrup can solve the problem with one of the most important systems of the body. Also, after a course of conservative therapy syrup notes calm children after feeding, in contrast to the hysteria in the presence of pathology of the digestive organs.
Duphalac for newborns
Child development does not end with the birth process, as a rule, most of the organs and systems takes place the last stages of formation is already getting into the adverse conditions of the outside world. This fact is observed in relation, for example, the gastrointestinal tract, for prenatal child's diet involves a completely different organs. Against this background, frequently observed in newborns constipation Because the lumen of the digestive tube is not ready for traditional products.
To eliminate these pathological states are appointed laxatives hypnotonic action Because the question may be whether the newborn Dufalac should respond positively with confidence - the drug - there is no doubt that the newborn need to address the difficulties with defecation.
How to give a newborn Dufalac?
The pharmaceutical preparation is produced in the form of a sweet syrup, because the instruction for infants does not differ from that of adult patients. Medicine can be diluted with water, so the taste was not so intense. Giving babies syrup should be at the same time (preferably immediately after sleep) in order to develop the habit of the young organism.
The laxative is a strong pharmaceutical product because when used Dufalac for infants, should strictly adhere to the dosage in order to avoid the adverse effects of the therapeutic course or overdosing the active components. Children from birth to the first year of life, usually given 5 ml for 15-20 days, but in the individual contra-indications or dosage or duration of treatment may vary.
Laxative for infants: reviews of Dufalac
Metabolic processes in the body are very young infants fast And therefore the therapeutic effects of the drug are observed in a few hours, unlike the treatment of adult patients. In this regard, comments on discussion forums for young mothers overwhelmingly characterize drug positive. After a course of conservative readjustment child becomes calmer and less worried parents screaming about without him. Frequency of defecation returns to normal (under one year is about 4-5 times a day).
Slimming
The problem of overweight in women is common in today's world and to solve it, of course, trying to paths outside first, and only after much research comes to sport and nutrition. There is a widespread view that the lose a few extra kilos by using such laxatives drugs, such as Dufalac. A large number of the female audience on niche sites ask how to drink syrup to get rid of obesity .
The correct answer of course is "no", as a laxative does not allow to eliminate the problem of obesity and drug abuse in the female body makes it worse. Due to the regular use of Duphalac to lose weight develops dehydration , Since a large amount of water for the suction output together with feces. This entails a series of pathological conditions, of which the key is total metabolic disorders .
As a consequence of metabolic shifts that occur regularly headache and dizziness Changes for the worse structural condition of the skin and its appendages ( nails become brittle and weak, and hair flogged lose a healthy shine and color). How fast action of the drug in such a way to a woman's body? When drug abuse above effect was fully manifested after 1-2 months of active laxative intake. It should be noted that the desired change in weight in most cases never comes.
Dufalac during pregnancy (and lactation)
and
no side effects
.
No comments:
Post a Comment