Ketonal

Description overdue on 27.09.2011

Related Articles:

• Instructions for use Neurobeks Forte
• Limfomiozot
• Reviews Fluimutsile - antibiotics for inhalation
• Vasari

Tweet

The main ingredient - Ketoprofen . It refers to a group NSAIDs . It has anti-inflammatory, analgesic (central and peripheral mechanisms) and antipyretic effects. Ketotifen has antibradikinnovoy inhibitory activity lipoxygenase It stabilizes lysosomal membranes, inhibits the activity neutrophil   patients rheumatoid arthritis . Ketonal binds to proteins of blood for 99% ( albumin ). Ketoprofen easily penetrates into connective tissue, synovial fluid. Desired therapeutic concentration of drug in the synovial fluid accumulates after 15 min. Ketonala after intramuscular administration in a dose of 100 mg. The drug is metabolized in the liver. The half-life of 1, 6-1, 9 hours. 99% PM outputted via the renal system, of about 1% - faeces.

Dosage Form:

Capsules (opaque), tablets, suppositories, vials, cream.

Indications:

Ketonal effectively relieves pain syndrome : In the postoperative period after traumatic injuries. The drug is used in renal colic, gynecology, neurology, dentistry, oncology. Anti-inflammatory effects in rheumatoid arthritis . osteoarthritis . nonspecific spondylitis . articular rheumatism . gouty arthritis . The drug is prescribed externally for sciatica, synovitis, sciatica, myalgia, tenosynovitis, sprains, strains, bursitis, bruises, phlebitis, lymphangitis, thrombophlebitis   superficial veins.

Contraindications:

Pronounced irregularities in the renal system, liver, gastrointestinal tract, disorders of the blood, pregnancy, proctitis, hemorrhoids (using a suppository), bronchospasm, allergic to ketotifen, acetylsalicylic acid.

Side effect:

Gastrointestinal tract : Dyspepsia, epigastric pain, flatulence In rare cases - bleeding.

Central nervous system : Drowsiness, dizziness, migraine , noise in ears.

Locally : Tenesmus, burning sensation, diarrhea, allergies, fatigue, transient dysuria.

Overdose:

Cases of drug overdose Ketonal not observed. There is no specific antidote. Treatment is symptomatic.

Special instructions:

Precautions Ketonal prescribed for diseases of the liver, renal system, ulcerative lesions of the gastrointestinal tract, the propensity to allergies, asthma, heart failure. When applying the cream to avoid the affected skin, open wounds, mucous membranes and eyes. During treatment, it is forbidden to drink alcohol. Ketonal reduces the speed of psychomotor reactions, operate machinery, driving vehicles to defer the period of treatment. Parenteral therapy   drug last several days. Upon reaching the desired effect ketonal continue to take the form of tablets, capsules, suppositories. The cream is applied 2-3 times a day with a thin layer on the skin over the lesion, gently rubbing the drug. The duration of treatment is 2 weeks (over - on doctor's advice).

The solution for infusion: the infusion solution vials of the drug due to increased sensitivity kept wrapped in foil or dark paper. Infusions are assigned solely in a hospital: the infusion on average - ½ h, a maximum - 48 hours. The dose of ketotifen is not more than 300 mg. Ketonal can be administered in combination with analgesic drugs of the central action.

Drug Interactions:

Diuretics, aspirin, drugs lithium NSAIDs, Methotrexate , Antihypertensive drugs, antidiabetic drugs administered simultaneously with Ketonalom strictly according to need and in smaller doses.