Description overdue on 12/11/2014
- Latin name: Pyridoxine
- ATC code: A11HA02
- Active substance: Pyridoxine (Pyridoxine)
- Manufacturer: OJSC "Veropharm", Russia.
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Cautions
- Side effects
- Instructions for the use of pyridoxine (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- Pyridoxine hair
- Reviews
- Price, where to buy
Composition
One ampoule of injectable solution the active ingredient is contained: pyridoxine hydrochloride 10 or 50 mg.
Additional ingredient: water for injections.
The tablet includes a composition of 2, 5 or 10 mg pyridoxine hydrochloride.
Product form
Pyridoxine hydrochloride in a solution for injection packaged in ampoules of 1 ml of 10 vials in a box.
The tablets are packed in a jar of 50 pieces.
Pharmacological action
The drug has an action, Fills deficit vitamin B6.
Pharmacodynamics and pharmacokinetics
As is known, vitamin B6 is an indispensable participant in metabolic processes, normalizes and supports the nervous system. The phosphorylated form of pyridoxine is a coenzyme significant number of enzymes which influence the non-oxidative exchange of amino acids, for example, decarboxylation or transamination. This component is essential for the metabolic processes tryptophan . cysteine, glutamine, methionine and other amino acids. It is important for the exchange of histamine and for normalizing lipid metabolism.
Metabolism of the basic substance in the liver, resulting in formation of a pharmacologically active metabolites: pyridoxal phosphate and piridoksaminofosfat . Components are distributed mainly in muscle tissues as well as in the liver and nervous system. It noted the penetration of the drug in breast milk and placenta. The substance is excreted in the kidneys, a part - of bile.
Indications
The drug used for the treatment and prevention of deficiency of vitamin B6 in:
- B6-gipovitaminoze;
- toxicosis pregnant;
- sideroblastic anemia;
- leukopenia;
- diseases of the nervous system;
- sea and air sickness;
- atherosclerosis;
- diabetes;
- dermatitis;
- herpes zoster;
- neurodermatitis;
- psoriasis;
- exudative diathesis and so on.
Contraindications
Do not take the drug if Sensitivity or intolerance Pyridoxine.
Cautions
It requires careful when appointing the drug to patients suffering stomach ulcer and 12 pёrstnoy ulcer, ischemic heart.
Reception of high doses of pyridoxine in severe liver damage may impair its performance.
Side effects
During treatment may develop allergic reactions , Hypersecretion of hydrochloric acid.
Instructions for the use of pyridoxine (method and dosage)
The tablets Pyridoxine instructions for use recommends ingest to treat hypovitaminosis . For adult patients assigned dose of 80 mg to reception 4 times a day.
Vitamins in vials as Pyridoxine-Vial , Instruction on the application specifies use daily dosage of 50-150 mg. Allowed subcutaneous, intramuscular or intravenous administration. Duration of therapy is determined by the severity and type of violation. By preventing a lack of vitamin B6 per day appointed about 40 mg.
Overdose
In clinical overdose are not established.
Cooperation
Concomitant use with isoniazid, cycloserine, penicillamine pyridoxine reduces efficiency. Marked pharmaceutical incompatibility of vitamin B6 to B1 and B12. This drug significantly reduces the activity of anti- levodopa.
Combination with g ormonalnymi contraceptives pyridoxine able to increase the concentration in the composition of blood plasma. Application to phenytoin and phenobarbital can reduce the concentration of plasma in the composition of these components.
Terms of sale
Vacation allowed the drug without a prescription, but it alone should not be used.
Storage conditions
The medicine should be stored in a dry, dark, cool place, protected from children.
Shelf life
3 years.
Analogs
Pyridoxine hydrochloride
Vitrum Vitamin E
Pyridoxine - it is a vitamin that is included in the plurality of combined preparations, for example: Magne Wb, Perneksin elixir Gepasteril-A-B Gepasteril, lipostabil, Essentiale.
Analogues of the drug are: Vitamin B6, Piridobene, Piradoksin, adermin, Betsilan, Pirivitol, Bedoksin, Benadon, Geksabetalin, Geksabion, Geksavibeks and others.
The combination Benfotiamine + Pyridoxine It is a fat-soluble analogue of vitamin B1 or thiamine . This combination normalizes the function of the nervous system, taking part in carbohydrate metabolism, making up for a deficiency of vitamin B1.
Alcohol
Excessive alcohol consumption reduces the absorption vitamin B6 , Increasing the need for it organism.
Pyridoxine hair
Very popular vitamin masks, home-cooked. For this purpose, pyridoxine often applied to the hair. It is known that the substance has a positive effect on hair growth, normalizes blood circulation.
To make a mask for the hair of medium length, used Pyridoxine-Vial ampoules - 4-5 pieces.
It is necessary to mix a spoonful of castor, olive oils, and burdock. This mixture to warm in a water bath, add a solution Pyridoxine-Vial and any other essential oils, which are suitable for the type of hair. All mix well and apply on hair. You can wear a hat and let stand for 30-40 minutes. Then, wash your hair, rinse well with cool water. Experience shows that such a tool not only makes the hair shiny and silky, but healthy and strong.
Reviews of pyridoxine
Medical sites and forums in most cases contain positive comments about pyridoxine. This drug is given to many patients in the treatment of a variety of disorders, such as: B6 vitamin deficiencies, leukopenia, atherosclerosis, diabetes, herpes zoster, psoriasis, neurodermatitis and so on. Almost always this vitamin greatly accelerates the healing effect.
However, some users asked Pyridoxine - what is it? And when they find out that the name of vitamin B6 greatly surprised. As you know, Pyridoxine is very good for pregnant women toxicosis, eliminates the symptoms of air and sea sickness. But the fact that the substance is used in combination therapy of diseases of the central nervous system, do not know many.
It should be noted that patients often do not use the drug in capsules and its tablet form.
Among the many positive reviews there have been reports of adverse effects. Some patients in the patients receiving the drug increased the acidity of gastric contents, cause severe pain in patients with gastritis. However, experts argue that compliance with the dosing and accounting contra - ulcers and gastric ulcers, do not lead to the development of side effects since the drug is well tolerated. In rare cases, develop an allergic reaction, but as a rule, all symptoms resolved after discontinuation of the drug.
Price pyridoxine, where to buy
The tablets Pyridoxine price varies between 40-60 rubles.
Price pyridoxine ampoules of 20-35 rubles.
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