Nemozol

Description overdue on 09/10/2013

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Anthelmintic agent.   Active substance - albendazole . The principle impact Nemozola based on the suppression of glucose utilization, to decrease the activity of cellular microtubule system in the intestinal tube parasites. Active ingredient selectively inhibits the polymerization of beta-tubulin protein, blocks the movement of secretory granules and other organelles in muscle tissue helminths. The combined effects of the drug causes the death of a parasitic agent. High efficiency Nemozola observed in the treatment of parasitic infections caused by nematodes Strongyloides stercolatis   and larval forms of cestodes Taenia solium   and Echinococcus granulosus .

Nemozol available in tablet form, and for children in the form of a slurry. After ingestion of the active substance albendazole poorly absorbed from the lumen of the digestive tract and is not detected in the plasma in an original form. Oral bioavailability reaches only 30%. Adsorption   medicament and the maximum concentration of the active substance in blood plasma increases 5 times, while a fatty meal. Active substance albendazole biotransformed in the liver before the primary metabolite system - albendazole sulfoxide, which also has antiparasitic activity. Metabolite fully distributed throughout the human body and is found in the cerebrospinal fluid, bile, urine, cystic fluid and cyst wall. In the pathology of renal excretion of the active agent and its metabolites is not changed. In diseases of the liver bioavailability Nemozol increases significantly. The active ingredient is an inductor of microsomal oxidation of cytochrome P450 enzymes and can accelerate the metabolism and excretion of many drugs.

Indications:

The drug is prescribed for peritoneal echinococcosis , Lung, liver (pathogen Echinococcus granulosus - the larval form of the dog   tapeworm ). Drug Usage Nemozol recommends prescribers at neurocysticercosis , Caused by a Taenia solium - the larval form of pork tapeworm . Albendazole is effective in enterobioze, trihotsefaleze, microsporidiosis , Opistorhoze, ascariasis, giardiasis, ankilostomidoze and mixed parasitic infestations. In the surgical method of treatment of cysts ehinokokkoznyh Nemozol pills prescribed as an adjuvant therapy.

Contraindications:

Application Nemozola contraindicated during breast-feeding, individual hypersensitivity to albendozolu and child bearing. When retinal pathology, pronounced changes in the hepatic system, liver cirrhosis at diagnosis suppression of bone marrow hematopoiesis   medication prescribed with caution after cupping of the acute stage of the disease and stabilize the patient's condition. Treatment Nemozolom contraindicated in allergic and hypersensitive alertness benzimidazole derivatives.

Side effect:

Reviews on Nemozol indicate a good tolerability of the drug in the pill and the suspension simultaneously with fatty foods. The digestive tract:   vomiting, epigastric pain, nausea, increased ALT and AST enzymes. Nervous system:   meningeal symptoms, dizziness, migraine pain. Bodies of blood:   decrease in the absolute number of leukocytes and platelets in the blood, agranulocytosis, granulocytopenia, pancytopenia . Allergic responses in the form of itching and rashes on the skin. The treatment with albendazole may develop alopecia Hyperthermia , Raising blood pressure, a functional change in the renal system. When you receive large doses recommended gastric lavage, the appointment of enterosorbents   and symptomatic therapy.

Mode of application:

Nemozol tablets are taken orally without chewing. The drug is recommended to drink plenty of fluids. Treatment with albendazole does not require compliance with the special diet and use of laxative medicines. How to take when Nemozol enterobioze, ascariasis and ankilostomidoze : Single dose of 0, 2 g of the recommended repetition after 3 weeks. When cestodosis and strongiloidoze:   for 3 days daily take on 0, 2 grams, 3 weeks course repeat. Nemozol children up to 2 years at cerebral cysticercosis   administered for 8 days, the daily dose is calculated according to the following scheme: 15 mg per 1 kg weight. If necessary, you can repeat the course anthelmintic therapy. Children over 2 years old treated for 8-30 days, appointing Nemozol suspension twice a day on days 0, 4 grams. Treatment for giardiasis:   daily intake of 0, 4 grams of albendazole for three days. Treatment of toxocariasis:   400 mg twice a day, the duration of treatment - 1-2 weeks.

Special instructions:

Nemozol price varies depending on the pharmacy network and the region (average cost of 100-150 rubles). When diagnosing leukopenia   anthelmintic treatment is stopped. Women are recommended before treatment to ensure the absence of pregnancy. It takes a full examination of the retina for the treatment of eye disease with neurocysticercosis. Patients who receive the medication in high doses, conduct regular monitoring of blood counts and liver functional state of the system (enzymes ALT, AST, bilirubin). It requires reliable contraception when taking Nemozola of worms. When neurocysticercosis conducted appropriate therapy anticonvulsant drugs and corticosteroids. In the first week of anthelmintic therapy steroids (parentelnye and oral form) is indicated for the prevention of hypertensive crisis . Buy nemozol at any pharmacy network without requiring presentation of a medical prescription form.

Drug Interactions:

Kontsetratsii albendazole sulfoxide active substance in blood is greatly reduced by concurrent therapy medicaments which contain in its composition cimetidine   and dexamethasone .