Study co-author Patrick Michel of the Institut du Cerveau and mohel Appin from Hopital de la Salpetriere in Paris genetically created a new breed of mice that do not have specific nicotinic receptor alpha 7 subtype, as well as mice with a functional receptor. Using embryonic tissue of mice, researchers worked on the culture of the brain to induce a state characteristic with a slow progression of the loss of dopamine neurons - is the initial stage Parkinson's disease .
The researchers found that nicotine has the potential to store dopamine neurons in cultures of normal mouse brain, but those rodents that were deprived receptors. "This study provides hope for a neuroprotective treatment in the early stages of Parkinson's disease, or even at a stage when the disease has not yet been diagnosed with the classic signs," - says Dr. Michelle.
The discovery allows researchers theoretically count on the development of new therapies for patients with Parkinson's, which would be aimed at nicotine receptors. But does this mean that the fans Smoking Area You can not be afraid of this disease?
"Do not hurry to rejoice, if you are a heavy smoker, - says Dr. Gerald Weismann, editor in chief of The Federation of American Societies for Experimental Biology Journal, which published the results of the study. - Even if the cigarettes and protect you from Parkinson's disease you about it soon just do not know. Because the disease develops in older age, and smokers often, until he simply did not hold out. Opening gives scientists hope to create a non-toxic ways to use nicotine receptors protection Parkinson's disease ".
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