Description overdue on 07/28/2014
- Latin name: Thioctacid
- ATC code: A16AX01
- Active substance: Thioctic acid (Thioctic acid)
- Manufacturer: GmbH MEDA Manufacturing, Germany
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Thioctacid (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Reviews
- Price, where to buy
Composition
Part tablets It included 600 mg thioctic acid .
Additional material: hydroxypropyl cellulose, magnesium stearate, low-substituted hydroxypropyl cellulose, hypromellose, titanium dioxide, Macrogol 6000, quinoline yellow aluminum salt, talc, aluminum salt indigokarmina - One tablet.
One ampoule preparation contains thioctic acid 600 mg (as trometamolovoy salt ) + Water purified and trometamol .
Product form
Coated tablet Convex, yellow with a green tinge. The bottle of 30 pieces.
Solution for intravenous injection yellow, transparent. The vials of dark glass, 5 pieces of 24 ml. In a cardboard package of 5 or 10 vials.
Pharmacological action
Metabolic means .
Pharmacodynamics and pharmacokinetics
Thioctic acid - Powerful antioxidant It refers to the group vitamin-like substances . The substance participates in the reaction oxidative decarboxylation of pyruvic acid and alpha-keto acid It is mitochondrial coenzyme complexes . On effect, the acid is similar to the vitamin B . It protects cells from the damaging effects free radicals It lowers blood glucose levels.
At reception of tablets, the active substance is rapidly absorbed and is adjudged to be into the systemic circulation. However, the simultaneous ingestion may reduce its concentration. It reaches a maximum of half an hour, about 70% bioavailability, half-life half an hour. Metabolized, eliminated via the kidneys.
Indications
The drug is indicated for the symptomatic treatment of:
- sensorimotor diabetic polyneuropathy ;
- polyneuropathy , Caused by taking alcohol.
Contraindications
In the absence of clinical trials and sufficient experience in the application means it is not recommended intake Thioctacid pregnant and nursing women, children and teenagers.
Contraindications allergy for any component of the formulation.
Side effects
While receiving the tablets may occur:
- allergic reactions (rash, itching skin, hives );
- adverse reactions from the GI (pain, nausea, diarrhea . vomiting ).
Adverse Reactions when administered medications intravenously:
- skin rash, pruritus, anaphylactic shock ;
- sharp increase intracranial pressure , Difficulty breathing;
- seizures, bleeding and minor bleeding, vision problems (rare).
Instructions for use Thioctacid (method and dosage)
Pills Thioctacid BV is carried out on an empty stomach, at least half an hour before breakfast. Typically, the drink for one tablet (600 mg of active ingredient) per day.
Instructions on Thioctacid 600 T
Administered intravenously very slowly, no more than 50 mg in 60 seconds.
The initial daily dose is 600 mg, one month dosage can be reduced by half.
Avoid long stay vials in the light.
Overdose
Symptoms of overdose are convulsions , Violations of blood coagulability, lactic acidosis Possible hypoglycemic coma .
You should immediately call a doctor, induce vomiting, take chelators , Wash out the stomach, support the livelihoods of the victim until the ambulance.
Cooperation
With combined with caution metal-containing agents . cisplatin . insulin , Drugs for diabetes. Not recommended combination with alcohol, due to lower efficiency of drugs.
The gap between oral iron or magnesium should be at least 6-8 hours.
Terms of sale
It requires a prescription.
Storage conditions
In a dark, cool place, not above 25 degrees. Keep away from children.
Shelf life
Pills - 5 years.
The ampules - 4 years.
Analogues of Thioctacid
Mummies
Omez JEM
Oktolipen
Tiogamma
Figurin
Actovegin
Berlition
Analogues Thioctacid 600 T and Thioctacid BV They are: A lfa-lipon , Tiogamma, Valium, Dialipon .
Reviews Thioctacid
Reviews on Thioctacid 600 T
Thioctacid - the preparation necessary to receive people suffering from severe metabolic disorders. Mixed reviews about it, means, of course, helps, but often show side effects such as urticaria, nausea, sometimes even hot flashes and sudden changes in mood health.
Reviews on Thioctacid BV
Reviews are the same as for solution for injection. The only side effects occur less frequently and not as pronounced. Generally, Thioctacid HR - A good way to combat the symptoms of polyneuropathy in diabetes and after long-term use of alcohol.
Price Thioctacid where to buy
Cost Thioctacid tablets, 600 mg is about 1600 rubles per 30 pieces.
A preparation in capsules It costs about 1566 rubles per 5 pieces of 24 ml.
Cost Thioctacid BV 600 , 100 tablets - 3200 rubles.
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