Immunoglobulin

Description overdue on 17.08.2011

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This drug - immunostimulatory and immunomodulatory agent. It contains many opsonizing   and Neutralizing antibodies Who actively resist bacteria, viruses and other pathogens. Furthermore, the number of fills Immunoglobulin lgG antibodies Lowering the risk of infections in patients with secondary and primary immunodeficiency. This drug has the ability to effectively fill and replace the patient's serum natural antibodies.

Bioavailability   to 100% with intravenous immunoglobulin. Between human plasma and extravascular space gradual redistribution of the active substance. Approximately one week between these environments is reached equilibrium.

Indications:

Immunoglobulin is prescribed, if necessary, replacement and replenishment of natural antibodies. Also, the drug used for the prevention of chronic lymphocytic leukemia , Syndromes secondary and primary immunodeficiency, bone marrow transplantation, agammaglobulinemia , AIDS in children, variable immunodeficiency, chronic lymphocytic leukemia. Immunoglobulin is recommended even in severe bacterial infections, hemolytic anemia, viral infections, Kawasaki syndrome , Red cell aplasia, hemophilia, thrombocytopenia and habitual abortion prevention.

Mode of application:

This drug is administered intramuscularly and intravenously drop by. Dosage assigned individually, depending on the type and severity of the disease, and the immune status of the patient and individual tolerability.

Side effects:

If using immunoglobulin the patient to adhere to recommendations for dosage and administration and precautions, the substantial side effects are very rare. Adverse effects disappear immediately after application of the drug. Typically, they occur because of the high rate of infusion of the drug.

Patients are sometimes observed following side effects: headache, weakness, fever, chills, malaise. Sometimes, there are shortness of breath and a dry cough; increased salivation, stomach ache, vomiting, diarrhea Nausea; flushing, tachycardia, cyanosis; weakness and drowsiness.

Contraindications:

Immunoglobulin can not be applied in the following cases: in anaphylactic shock, diabetes mellitus, exacerbation of allergy, renal insufficiency. The drug should prescribe with caution to patients suffering from diseases such as immune diseases of the blood, collagen, jade.

Special instructions:

Immunoglobulin during pregnancy can be used strictly according to recommendations of your doctor. Studies on the effect of drugs on pregnant women were not conducted. Protective antibodies can be transmitted to an infant through breast milk.

Do not use this drug when in solution appear suspended particles, flakes, it changes its transparency.

In no event should not be administered intravenously preparations intended for intramuscular use. This can lead to kollatpoidnym reactions .

Connectivity:

Do not mix Immunoglobulin with other drugs. During infusion, always use a separate dropper.

Overdose:

Symptoms of overdose is hypervolemia and increased blood viscosity. This is true for the elderly and persons with disorders of the kidneys.

Storage conditions:

Immune globulin must be kept in a dark, warm place. The temperature should be from two to ten degrees, the drug need not be frozen. The packaging will be specified retention period.