Description overdue on 13.11.2011
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The preparation Meridia It is used to treat obesity . Active substance sibutramine acts in vivo due to inhibition of reuptake of monoamines metabolites . The synapses increases the content neurotransmitters That stimulates the activity of the central 5-HT serotonin- and adrenergic receptors . The result is shown satiety in a patient is significantly reduced need for food, thus increasing termoproduktsiya . There is also an active influence on the brown adipose tissue by activating b3-adrenoceptor .
Indications and methods of use of the drug:
The drug is prescribed for patients with Meridia alimentary obesity Whose body mass index greater than 30 kg / m2. It is used in alimentary obesity with a BMI of 27 kg / m2 or more, which combines non-insulin diabetes or dyslipoproteinaemia .
The dose of the drug receiving specialist should set individually.
The initial dose should be 10 mg. If the effect is not observed, that is, it resets the patient for at least 2 kg for four weeks, then if tolerated dose of agent can be increased to 15 mg per day. In the absence of effective exposure treatment should not continue. Capsules of the drug is taken in the morning, drink should be plentiful. Eating at the same time does not matter.
No need to continue therapy after three months of taking the drug to those patients who have failed to lose weight during this time by 5% from the initial level.
We should not practice further treatment, if after a weight loss during the treatment according to the patient drugs gaining more than 3 kg. Duration of drug Meridia may not last bole two years after the security information of the drug over a long period of time is absent.
Contraindications and possible side effects:
The drug should not be used in the presence of these diseases and causes: organic prerequisites to obesity, severe eating disorders, mental illness, de la Tourette syndrome . You can not use the drug while treating MAO inhibitors or when used for two weeks before you start taking Meridia, taking reuptake inhibitors Serotonin , Hypnotics, drugs that contain tryptophan And other drugs for weight reduction of the central action. Contraindications This drug is also in diseases of the cardiovascular system, uncontrolled hypertension . thyrotoxicosis , Severe violations of the liver, kidneys, pheochromocytoma , Benign prostatic hyperplasia, angle-closure glaucoma, pregnancy and breastfeeding. The drug should not be taken for children, adolescents, people over 65, those who have seen drug, alcohol, drug dependency, high sensitivity to sibutramine.
Carefully appointed agent for arrhythmias at history . cholelithiasis , Congestive heart failure, hypertension , Neurological disorders, disturbances in the functioning of liver, kidney, mild to moderate, with a history of motor and verbal tics.
Adverse effects during the treatment may occur during the first week of use of the drug. Over time, they become less pronounced.
In the CNS and peripheral nervous system may cause insomnia, dizziness, headaches, paresthesia , Anxiety, change in taste. In the cardiovascular system is manifested tachycardia, increased blood pressure, vasodilatation .
In the gastrointestinal tract may be dry mouth, loss of appetite, constipation ; sometimes it may appear nausea, exacerbation Hemorrhoids . As a side effect may appear high perspiration. Also disclosed are isolated instances of dysmenorrhea , Edema, influenza-like syndrome, back pain and abdominal pain, pruritus, increased appetite, thirst . depression . sleepiness . rhinitis . anxiety , Irritability, acute interstitial nephritis, bleeding, Henoch-Schönlein . seizures . thrombocytopenia .
Specific recommendations:
This tool should be used only in cases where diet, exercise does not have the desired effect, then there are lots of 3 months has decreased by less than 3 kg. Use of the drug Meridia should be done only under the close supervision of a specialist. It is necessary in this case to adopt an integrated approach to the problem, that is, to make a change principles of nutrition, increase physical activity. In the process of treatment is necessary to keep under control the blood pressure and heart rate. If you double-control when measuring blood pressure exceeds 145/90 mmHg, the Message reception is suspended.
When you miss a dose two tablets in the following should not be accepted. Meridia not combined with alcoholic beverages, so-as alcohol violates the scheme diet, the recommended while taking the drug. The drug can affect the ability to work with dangerous machinery and driving vehicles.
Drug should be stored according to the rules storage of medicines from the list of B. Keep away from children's access and ingress of moisture. Storage temperature should not exceed 25 ° C.
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