Description overdue on 08/12/2014
- Latin name: Mometasone Furoate
- ATC code: D07AC13
- Active substance: Mometasone (Mometasone)
- Manufacturer: PAO Farmak, Ukraine; S.p.A Sterling S.N.I.F.F., Italy; ZHEJIANG TIANTAI AURISCO PHARMA & CHEMICAL Co.Ltd, China
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on mometasone (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One gram of the cream contains 1 mg of active substance mometasone furoate + Additional ingredients (hexylene glycol, titanium dioxide, aluminum salt octenyl succinate starch, water, white petrolatum, glyceryl monostearate, macrogol cetostearyl ether, white wax, diluted phosphoric acid).
Single gram of ointment contains 1 mg mometasone furoate White wax, white petrolatum, propylene glycol mono-palmitostearate, hexylene glycol, water, dilute phosphoric acid.
Product form
The cream and ointment are white or almost white. They are produced in tubes of 15 grams, in a cardboard box 1 tube.
The spray produced in plastic bags at 200 or 500 grams, with aluminum drum at its end.
Pharmacological action
Anti-inflammatory, vasoconstrictor, antiexudative .
Pharmacodynamics and pharmacokinetics
Mometasone - Synthetic glucocorticosteroid . The drug is used for topical application. This systemic effect means not shown, the drug constricts blood vessels, reduces inflammation and itching. The tool has also antiexudativ and antiallergic effect.
The active ingredient inhibits the process of developing mediators inflammation ( prostaglandins ) Simultaneously increases secretion inhibitor phospholipase A - lipomodulina .
The drug reduces the granulation and infiltration Allergic reaction do not occur.
The drug affects mostly local. Its systemic absorption is very low.
Indications
Means in the form of creams and ointments prescribed for the treatment of dermatitis, hyperkeratosis : eczema, psoriasis, atopic and seborrheic dermatitis .
Intranasal formulation used in allergic rhinitis (treatment and prevention), acute sinusitis.
Contraindications
The drug is not used:
- reactions in the presence of hypersensitivity on the components of the means;
- at tuberculosis ;
- hay fever nasal (children under 18);
- Children under 2 years old;
- at fungal, bacterial or viral systemic infection;
- If you recently experienced an injury or nose surgery was performed;
- In diseases caused by Herpes simplex With lesions in the eye area.
Side effects
When local use can include itching, burning sensation, paresthesia , Rash, the appearance of hair on the treated area, the appearance striae . sudamen . folliculitis .
When using intranasal itching, dryness of mucous membranes, fungus . bronchospasm . irritation .
Instructions on mometasone (method and dosage)
Depending upon the dosage form employed, the disease and its severity, route and dosage vary greatly and must be determined by the attending physician.
Mometasone Ointment, instructions for use
The ointment or cream is applied to a thin layer to the affected area once a day. The course of treatment prescribed by a doctor.
Guide to Spray
For one press of the applicator 100 mg of the drug is released.
For adults and children over 12 years, recommended by 2 inhalations in each nostril, 1 times a day. The daily dose - 200 mg spray. Maximum - 400 micrograms.
As prophylaxis designate one inhalation per day.
For children from 2 to 11 years, the maximum daily dosage is 100 micrograms.
Overdose
In overdose likely to develop Cushing . May be released from his nose bloody clots.
In case of overdose, discontinue use of the funds in the urgent need to correct electrolyte imbalances.
Cooperation
Cases of drug-drug interactions are not described. The drug is incompatible with alkali .
Terms of sale
Prescription.
Storage conditions
In a cool place, away from children. Avoid exposure to spray with a spray of fire.
Shelf life
3 years.
Cautions
If the patient has previously received systemic corticosteroids, and then moved to the inhalation form, should be particularly careful. Significantly increases the risk of adrenal insufficiency . Keep in mind that for the recovery of the body after receiving systemic GCS It may require 2-3 months.
With long-term and systematic use of the funds necessary to carry out periodic medical examination.
The drug should not be used to quickly arrest bronchospasm .
In the application means it is not recommended to contact with sick varicella . Measles or other severe infections, due to the strong decline immunity . This is especially true of children under 18 years.
Fundamentally in treatment use the lowest effective dose to avoid suppression hypothalamic-pituitary-adrenal axis .
When receiving means children may be a delay of physical development.
Analogs
Beloderm
Uniderm
Momat
Akriderm
Elokim
Flutsinar
Sinaflana
Tselestoderm
The closest analogues: Momat, Nasonex, Elokim Uniderm, Tvistheyler, mometasone .
During pregnancy and lactation
Talk to your doctor.
Reviews
Reviews of ointments and creams are good. The tool helps to get rid of the rash on the skin, noticeable effect occurs within 10 days of application. However, according to some reports, the drug is addictive and long-term use is necessary to increase the dosage. Also, the drug can sometimes cause burns in the interaction with ultraviolet radiation.
Price mometasone
Determine the price of spray mometasone furoate and mometasone furoate price in the form of cream at the moment is difficult.
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