Description overdue on 07/12/2014
- Latin name: Afloderm
- ATC code: D07AB10
- Active substance: Alclometasone (Alclometasone)
- Manufacturer: Belupo (Croatia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Afloderm (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Reviews
- Price, where to buy
Composition
The preparation contains as active substances alclometasone dipropionate .
Cream Afloderm also a part of the following additional ingredients: propylene glycol, sodium dihydrogen phosphate dihydrate, cetostearyl alcohol, macrogol glyceryl stearate, sodium hydroxide, chlorocresol, phosphoric acid, macrogol tsetostearat, soft white paraffin, purified water.
In turn, the cream contains the following excipients: white soft paraffin, propylene glycol monopalmitostearat, beeswax white, hexylene.
Product form
In pharmacies sold cream and ointment Afloderm.
Pharmacological action
The drug has anti-inflammatory . antipruritic . antiallergic and antiproliferative properties.
Pharmacodynamics and pharmacokinetics
The drug acts as a anti-inflammatory . vasoconstrictor and stops itch means. It is believed that its active ingredient induces the synthesis of inhibitors phospholipase A2 . As a consequence of phospholipids release membranes decreases arachidonic acid . This causes inhibition of synthesis prostaglandins and leukotrienes from arachidonic acid .
When applied topically Afloderm a healthy skin area of 3% of the active substance is absorbed into the bloodstream. If the skin is damaged or used occlusive dressing Degree Absorption It may be higher.
Drug is cleaved in the liver. Most of metabolites excreted in the urine, the rest - in the bile.
Indications
The medicine is prescribed for:
- atopic dermatitis ;
- psoriasis ;
- solar dermatitis ;
- eczema ;
- allergic and contact dermatitis ;
- allergic reactions insect bites .
You can apply this tool for children from 6 months.
Contraindications
The drug is contraindicated in:
- hypersensitivity to its components;
- skin manifestations Syphilis ;
- Viral infections of the skin;
- open wounds;
- trophic ulcers ;
- tuberculosis of the skin ;
- varicella ;
- Skin post-vaccination reactions ;
- children aged up to six months.
Side effects
The cream and ointment rarely cause negative reactions. As possible side effects rash, erythema Irritation, itching, dry skin, acne . In rare cases, it reported on the changes of the skin, resembling acne . folliculitis , Banners, hypertrichosis , Secondary infections of the skin, hyperpigmentation . atrophic skin changes, expansion of surface vessels, allergic contact dermatitis . Adverse reactions at the site of most manifest when using occlusive dressings .
Systemic side effects can lead to adrenal suppression. It is assumed that this is possible with prolonged use on the skin of a large area.
Instructions for use Afloderm (method and dosage)
Cream Afloderm application instructions recommend the use for the treatment of acute skin lesions, and ointment - for the treatment of subacute and chronic dermatosis .
Once completed the acute phase of the disease, and if the drug is used in dense areas of the skin or the need to remove the inflammatory effect in the denser layers of the skin, it is desirable to use Afloderm as an ointment.
The drug is in the form of a cream is easily absorbed and leaves no greasy.
The drug is applied evenly with a thin layer to the affected skin. This should be done 2-3 times per day. If you need to apply a cream or ointment on the areas where the skin is more dense, for example, elbows or feet, as well as easily erased, the medicine can be applied more often.
Instructions for use Afloderm reports that children, when the main symptoms begin to take place, the tool can be used 1 time per day.
In order to prevent relapse treatment should continue for some time after the skin returns to normal.
In the application for small children must be taken into consideration that skin folds and synthetic diapers may affect as well as occlusive dressing . Thus, the degree of absorption of the active component increases. Furthermore, in children absorption be higher due to immaturity of the skin.
It is not advisable to apply the cream and ointment under occlusive dressings in areas where the diaper and diapers touch the skin. Therapy for children lasts a maximum of 3 weeks. If you want to use the drug for longer, it should be done under the supervision of a specialist.
If the effect of the drug is not visible for two weeks, it is necessary to check the diagnosis.
Overdose
If the drug is applied to a large area of land during prolonged treatment, and using occlusive dressings and in childhood, the active ingredient can be absorbed to a greater extent. This can then lead to glycosuria . hyperglycemia , Suppression of the hypothalamic-pituitary-adrenal axis with slowing growth Cushing's syndrome and intracranial hypertension .
In rare cases possible fever . arthralgia . myalgia , General weakness.
When symptoms of an overdose of the drug you want to cancel. Treatment is symptomatic. The usual measures to maintain normal body functions.
Cooperation
Meaningful interaction with other drugs has not been established.
Terms of sale
Buy this drug may be without a prescription.
Storage conditions
Optimum temperature - 30 ° C. Keep the medication you need in reach of small children.
Shelf life
For ointment shelf life - 3 years, and cream - 2 years.
Analogs Afloderm
Ftorokort
Dermoveyt
Lorinden
Lokoid
Pharmacies can be found the following analogues Afloderm:
- Latikort ;
- Lokoid ;
- Lokoid Krehl ;
- Lokoid Lipokrem ;
- Fokort-Darnitsa ;
- Ftorokort .
Before you use any of them, you should become thoroughly familiar with the peculiarities of each tool.
Reviews Afloderm
Reviews of ointments and creams on the Internet you can find very different. Most people medication helps. Those who have tried the cream or ointment Afloderm noted their rapid action and efficiency. The favorable influence of the noticeable from the first days of use. Parents who used the drug for children, reviews Afloderm also leave positive.
However, there are those to whom the drug is not approached. They say that the remedy was not effective. As a rule, I write about the people who tried to remove with the help of inflammation in the tight areas of the skin. But the side effects of almost not reported. In general, the drug is well tolerated.
Price Afloderm where to buy
Price Afloderm hardly varies depending on the release form. The tool is generally considered very affordable. In ointment tubes Afloderm price for 40 grams on average 400 rubles. A vehicle in a tube 20g costs about 330 rubles. The average price of cream is approximately the same.
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