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Contraception . It is a combination drug, the composition comprises two active components: norgestimate and ethinylestradiol . The drug suppresses Ovulation due to inhibition of synthesis gonadotropins , Suppression of work hypothalamic-pituitary system . Silest implantantsionnuyu able to change the ability of the endometrium, reducing transport function of the fallopian tubes, increases the viscosity of cervical mucus. Available in tablet form.
Indications and contraindications:
Silest prescribed as a contraceptive. The drug is not used with a deficit of antithrombin 3, thromboembolism . thrombophlebitis , Norgestimate and ethinyl estradiol intolerance. Silest contraindicated in breastfeeding, endometrial tumors, breast, when estrogen dependent tumors, sickle-cell anemia, pregnancy, cerebrovascular disorders, tumors of the liver, liver failure, severe course Diabetes , Liver tumors, high blood pressure, bleeding of the genitourinary system, coronary heart disease, cerebrovascular diseases , Lipid metabolism disorders, mononucleosis, otosclerosis , Hemolytic anemia. When uterine fibroids ulcerative colitis , Liver disease, tuberculosis . mastitis , Depression, kidney disease system, epilepsy, adolescents administered with caution.
Side effect:
Silest can cause eating disorders, worsening cholelithiasis , Breast tenderness, nausea, vomiting, high blood pressure, chloasma, decreased libido , Changes in body weight, fluid retention, depression, headache, worsening of renal diseases system.
Mode of application:
Silest pills taken orally. To start the treatment on the first day of the menstrual cycle. The drug is taken daily for 20 days to 1 tablet then does not take the medication for seven days. During this period the woman should appear menstrualnopodobnye bleeding. After a seven-day break, the cycle of the drug is resumed. Silest desirable to take at the same time every day.
Special instructions:
After completion of dosing Silest women's reproductive function is restored, the sex glands start working in full and the usual mode, providing full and healthy birth . Use of the drug after a miscarriage, abortion, childbirth is recommended to begin after the first menstrual cycle . Before therapy, and every six months, you must undergo a gynecological, general medical examination, including blood pressure monitoring, urinalysis, cholesterol levels, the study of mammary glands, liver . At the initial stage of the drug while breastfeeding may experience a decrease in the amount allocated milk . Silest excreted in breast milk in small amounts . Women with nicotine dependence when taking oral contraceptives increased risk of developing cardiovascular disease (severe complications can not be excluded as a heart attack . stroke ). The risk depends on the age and number of cigarettes smoked per day. Vomiting and diarrhea, there is a decrease contraceptive action of the drug. If pregnancy occurs the treatment of an emergency stop. An increase in blood pressure, retrosternal pains, stabbing pains in the lungs and coughing, cerebrovascular disorders, visual impairment, occurrence of jaundice, phlebothrombosis, the first sign of phlebitis priemenie drug Silest stopped. While receiving the drug may cause bleeding that does not require discontinuation of therapy. When strongly pronounced bleeding necessary to gynecological examination. Regular intake of alcoholic beverages leads to a decrease in efficacy Silest.
Drug Interactions:
Phenytoin, carbamazepine , Antiepileptics, barbiturates, pyrazolone derivatives, sulfonamides may increase the metabolism of steroid hormone medication. When concomitant administration of antibiotics (eg, rfampitsin, ampicillin, etc.) there is a decrease contraceptive effectiveness, due to changes in the intestinal microflora, and requires the use of additional methods for protection against unwanted conception. Use of a progestogen-estrogen drugs require dose adjustment hypoglycemic agents .
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