Description overdue on 03/08/2014
- Latin name: Desitin
- ATC code: D02AB
- Active substance: Zinc oxide (Zink oxide)
- Manufacturer: Pfizer H.C.P. Corporation, USA
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Desitin: Dosing and dosing regimen of the drug
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Reviews
- Price, where to buy
Composition Desitina
In addition to the active component, which performs the role zinc oxide Composed Desitina as auxiliary substances include:
- white petrolatum (Vaselinum album);
- fish fat from the liver of cod fish (Oleum jecoris Aselli);
- talc (Talcum);
- butylhydroxyanisol (Butylated hydroxyanisole);
- anhydrous lanolin (Lanolinum anhydricum);
- methylparaben (Methylparaben);
- Flavored oil .
These components provide a good absorption of the drug and its uniform distribution of the active substance on the basic physical phase. They are also characterized by a number of features that complement and enhance the action zinc oxide .
Product form
The dosage form of the drug Desitin - ointment 40% for external use. In the sale it enters the packed in cartons of plastic tubes capacity '57
Ointment It has a dense viscous consistency, homogeneous (with a small grain size) and has a characteristic smell of cod liver oil.
Pharmacological action
Desitin cream has expressed:
- astringent;
- anti-inflammatory;
- adsorbent;
- a drying;
- antiseptic action.
Pharmacodynamics and pharmacokinetics
Zinc oxide It refers to the group of anti-inflammatory drugs for topical application. It is a slightly toxic amorphous powder odorless, white or somewhat yellowish.
Powder is able to absorb carbon dioxide from the air, is not soluble in water and ethanol Soluble in dilute mineral acids, acetic acid As well as alkaline solutions.
Zinc oxide stimulates denaturation of proteins and facilitates the formation of albuminates . When applied to the affected areas of the skin, it reduces the severity of exudative phenomena takes inflammation and tissue irritation, the skin creates a protective barrier to irritants action of external factors.
Cream Desitin used solely as an external agent. Adsorbing with skin excess fat and sweat, it prevents the development of diaper dermatitis in children and even in the early stages inhibits the development of inflammatory reactions.
In addition, the cream on the affected area forming a protective layer which helps neutralize the effects of the negative impact on the skin of urine, salts and other irritants, and effectively softens.
The pharmacological action and therapeutic efficacy of the drug is determined by the activity contained therein zinc oxide and cod liver oil, uniformly distributed in the fatty phase, which consists of anhydrous lanolin and white petrolatum .
Since fish fat . lanolin and petrolatum are products of natural origin, which is formed after application onto the skin Desitina film similar in structure to naturally potozhirovym layer which also performs the barrier function.
The film is well retained on the skin and mucous membranes, while maintaining its activity in a few hours. This is especially important at night when the baby skin contact with wet clothes and diapers longest.
Desitin also has a moderately severe astringent properties, it can be used to reduce the severity of inflammation and relief for minor burns and damage the integrity of the skin (such as scratches and cuts). A similar effect was also observed when using it to relieve symptoms eczema .
Data on the pharmacokinetic parameters of the drug available.
Indications
Desitin is recommended:
- at dermatitis various etiologies (including diaper dermatitis in infants);
- for the treatment of superficial Wounds ( scratches . cuts . abrasions etc.);
- if small areas of slack burns origin of various nature (solar, thermal, chemical, etc.);
- to eliminate Diaper Rash ;
- to relieve symptoms prickly heat in children;
- at bedsores ;
- in the presence of ulcerative lesions of the skin (including sores );
- treatment eczema in periods of acute illness;
- in simple Herpes ;
- purulent skin lesions provoked streptococcal infection .
Contraindications
The only contraindication to the drug is an individual sensitivity to any of its constituent components. Using Desitina allowed even to patients with severe medical conditions.
Side effects
Side effects during treatment ointment It has been identified.
Instructions on Desitin: Dosing and dosing regimen of the drug
With Diaper dermatitis infants therapy with cream Desitin begin with the appearance of symptoms such as rash . diaper rash and irritation of the skin. The drug is applied to the affected areas with a thin layer three times a day. If necessary, increase the number of procedures.
Before applying ointment Desitin must first prepare your skin: Wash with warm water and dry well. Standard practice is to use Desitin every time you change the diaper or diaper. The optimum number of surface treatments affected - from four to six times throughout the day.
Typically, a cure diaper dermatitis It takes two or three days, after which you can continue to use Desitina prophylactically. Prevention involves the application of the drug to those areas of the skin, which will be closed diaper or diaper and potentially in contact with urine and faeces .
Prophylactic use is especially useful at night and in cases when it is assumed that the child will be a long time in a particular clothing (for example, during a trip to the store or a trip to the clinic).
For prevention diaper dermatitis the drug may be used for a long period of time, when it is allowed to put the drug on an absolutely clean and healthy skin.
In a similar manner when used Desitin and other allergic rashes . diathesis and atopic dermatitis infants with oprelostyah in neonates.
People suffering from acne It is recommended to apply the drug once or twice a day - morning and evening, for example - within one to two weeks. During the day, the skin is cleaned from the remnants of the cream and allow it to "breathe" for at least an hour (optimally - in the open air).
When a single acne cream is applied to them before bedtime dot. Continuously use the permitted during the month.
In the treatment of wounds and burns Instructions for use Desitina recommends applying means of a thin layer on the affected area, if necessary, a sterile covering gauze or bandage.
It is important to remember that the drug may be used only if the surface and uninfected damage. If on the skin developed infectious process, it is impossible to apply the cream.
Overdose
Today Desitinom overdose have been identified. This is because the drug is practically not absorbed into the bloodstream.
Cooperation
The drug does not interact with other drugs does not cause any changes in the processes of absorption, distribution and excretion out of it.
Terms of sale
The drug is allowed to be used as a non-prescription drug.
Storage conditions
Desitin is stored in a place inaccessible to children at temperature not exceeding 30 ° C.
Shelf life
Usable for 3 years.
Cautions
When using Desitina avoid hitting the composition in the eye. After applying the product on your skin, wash your hands.
If after two or three days on the background of the drug rash do not disappear, it is advisable to consult a doctor for examination and further diagnosis.
Before applying ointment it is necessary to assess the smell. Usable drug normally has a poorly defined peculiar smell, similar to smell fish oil . Failure to comply with the storage conditions Desitin can deteriorate and lose their pharmacological efficacy.
The evidence of his unfitness is a distinct unpleasant odor rotten fish . This cream should be discarded, put it on the skin can not.
Analogs
Sudocrem
Tsindol
Zinc ointment
The pharmaceutical market in Russia and Ukraine is not submitted the same and synonymous Desitinu means. As Desitin they contain as active substance zinc oxide a. Analogs of the same which would have a similar effect, but characterized by a different composition of active and auxiliary components are missing.
Synonyms Desitina are:
- dermotropic means Tsindol Which is available as a suspension for outdoor use;
- Zinc oxide liniment;
- zinc ointment ;
- Zinc paste .
Reviews Desitine
The vast majority of reviews Desitine - positive. This is due to the fact that the drug has a pronounced therapeutic effect in the first few hours after application.
Against the background of its application has been a rapid disappearance of rashes on the skin, acne and Acne Accelerated offensive remission at atopic dermatitis And the process of healing of surface skin lesions and burns , Reduce or eliminate the symptoms inflammation . All this is a clear demonstration of the excellent therapeutic properties of the drug.
Also, the forums are full of a lot of positive reviews on Desitin for newborns. Average rating cream - 4, 5 on a 5-point scale. Many mothers of infants note that using Desitin, able to cope with diaper rash . redness and rash even in cases where other drugs have been powerless.
Furthermore, all the advantages as noted in the drug that:
- it can be used for a long time;
- it effectively eliminates the unpleasant symptoms, even in extreme heat;
- it is suitable for sensitive skin.
There are, of course, negative reviews, but almost all of them are connected not with the effectiveness of the drug, and its specific smell. For some patients during treatment with increased means xerosis . The latter, however, is rare and is caused in the first place the level of individual sensitivity to the drug.
Price Desitina
Price Desitin cream in different pharmacies and cities may vary. Some influence on pricing has also the fact that the drug markets of Russia and Ukraine come from both the United States and Canada.
However, as a rule, the difference in value of the Canadian and American products is negligible: for the Russian market, it is about 10 rubles for Ukrainian - 2-3 hryvnia.
The average price of cream in Ukraine 65 hryvnia. Buy Desitin in Kiev and other major cities (eg, Donetsk, Odessa and Kharkov) as you can in the usual pharmacy chains, as well as through online pharmacies.
The feasibility of such a purchase can be estimated by comparing the price of Desitin ointment on the Internet (including delivery) by the average market price in urban pharmacies.
In Moscow and other major Russian cities cream sold an average of 200-210 rubles per pack capacity '57
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