Description overdue on 07/23/2014
- Latin name: Flamax
- ATC code: M01AE03
- Active substance: Ketoprofen (Ketoprofen)
- Manufacturer: Sotex PharmFirma (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Flamaksa (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Flamaks capsules (1 capsule) in the composition comprising the active ingredient Ketoprofen (50 mg) and additional substances: MCC, lactose monohydrate, sodium lauryl sulfate, croscarmellose sodium, colloidal silicon dioxide, povidone.
Flamaks Forte tablets It contains 100 mg of active substance Ketoprofen (One tablet), as well as additional ingredients: rice starch, lactose monohydrate, croscarmellose sodium, colloidal silicon dioxide, MCC, povidone, sodium lauryl sulfate, macrogol 6000, magnesium stearate, hypromellose, talc, titanium dioxide.
Flamaks in solution one ampoule (2 ml) contains 100 mg ketoprofen . Also includes additional substances propylene glycol, benzyl alcohol, ethanol, sodium hydroxide, water for injections.
Product form
Flamaks (Flamax) is produced in the form of capsules, a solution for intravenous and intramuscular administration, rectal suppository, lyophilisate for the subsequent preparation of a solution, tablets, capsules.
Capsules Flamaks They have a white body and a blue cap, contained in white powder that has a uniform consistency.
Solution contained in a 2 ml ampoule with colored ring fracture or a notch. The Valium planimetric package contains 5 vials.
Flamaks Forte produced in the form of round biconvex tablets blue, which are coated with a film cover. The blister pack contains 10 tablets in a cardboard blister pack 2 is placed.
Capsules Flamaks forte contained in a container made of plastic which is placed in a pile of cardboard.
Pharmacological action
The drug has on the body antiagregatine, analgesic, anti-inflammatory, antipyretic effects. Analgesic effect and cause central and peripheral mechanisms.
Pharmacodynamics and pharmacokinetics
Ketoprofen It communicates with the blood in the body to 99%, mostly to albumin. The highest concentration in plasma is reached relatively quickly. Ketoprofen quickly into the connective tissue and synovial fluid. 15 minutes after a single administration of the drug intramuscularly, there is a high concentration of active agent in the synovial fluid. She saved up to 30 hours, so it is possible to reduce pain and stiffness in the joints for a long period of time. The BBB in significant quantities not penetrate.
Metabolism ketoprofen It occurs primarily in the liver. There is the process glyukuronirovaniya, after which form esters and glucuronic acid. They then excreted by the kidneys. The half-life of ketoprofen ranges from 1 6 to 1 9 hours.
Indications
Medicine Flamaks and Flamaks Forte It is used to symptomatic treatment of pain and inflammatory processes of various origins in their moderate intensity:
- diseases of the musculoskeletal system of man ( arthritis . rheumatic soft tissue . ankylosing spondylitis . osteoarthritis );
- sciatica . neuralgia . lumbago ;
- migraine Pain after surgery;
- painful menstruation , Inflammation of the pelvic organs;
- the pain and inflammation after injuries;
- toothache;
- pain when onkoboleznyah.
Contraindications
Flamaks (Flamax) does not apply in the following cases:
- High sensitivity;
- the period of acute gastrointestinal ulcers and erosions;
- aggravation of inflammatory bowel disease;
- bleeding from the gastrointestinal tract;
- acute phase of kidney disease, severe liver failure.
- hyperkalemia;
- progressive kidney disease;
- the combination of recurrent nasal polyposis, or asthma intolerant NSAIDs, in particular acetylsalicylic acid;
- hemostatic disorders . hematopoiesis ;
- after coronary artery bypass grafting ;
- the third trimester of pregnancy and breast feeding;
- patient age of 15 years.
Gently used in medicine hypertension . asthma , Edema, chronic Heart Failure . sepsis . diabetes . renal failure , Ischemic heart disease, severe somatic diseases.
Side effects
You may experience these side effects:
- Digestive system : dyspepsia , Abdominal pain, change in taste, abnormal liver function, stomatitis, changes in taste. Prolonged treatment with high doses of drugs may be bleeding stomach, gums, and sores in the gastrointestinal mucosa.
- Nervous system : insomnia . headache , Nervousness, dizziness , Headache, drowsiness or symptoms of increased excitability, memory impairment.
- Senses : Blurred vision, tinnitus, pain and dryness in the eyes, hearing impairment, conjunctival hyperemia .
- Cardiovascular system : tachycardia , Increased blood pressure.
- Forming Organs : anemia . agranulocytosis . leukopenia . thrombocytopenia .
- The urinary system : cystitis . urethritis , Irregularities in the kidney, jade . hematuria .
- Allergic symptoms : Rash, itching skin, swelling, rhinitis . bronchospasm . dermatitis .
- Other manifestations : hemoptysis , Heavy sweating, muscle twitching, shortness of breath, myalgia, epistaxis. In the treatment with high doses of the drug may vaginal bleeding.
Instructions for use Flamaksa (method and dosage)
If a patient starts treatment with Flamaks, instructions for use should be carefully studied them.
Injections (solution) administered intravenously and intramuscularly. Intravenous administration is carried out exclusively in a hospital. On average infusion continues 0, 5-1 hr., Maximum - 48 hours. Wherein the dose of the drug should not exceed 300 mg. In brief infusion 100-200 mg means diluted in 100 ml of 0 9% sodium chloride solution, the introduction lasts no more than 1 hour. The next time the drug may be administered after 8 hours. During continuous infusion of 100-200 mg means diluted in 500 ml infusion, administration is continued for 8 hours. The next time the drug can be administered within 8 hours.
Flamaks intramuscularly administered at 100 mg 1-2 times a day.
Capsules Flamaks It needs to be taken orally, during a meal. The dosage prescribed by the physician depending on the disease. The maximum dose of the agent per day - 300 mg.
Instructions for use Flamaks Forte It provides that the tablets should be taken orally in the meal. Usually assigned to receive 1 tablet 2-3 times a day. Permissible daily dose - 300 mg.
Overdose
Overdose money is not dangerous. It may occur dizziness . headache , Vomiting, abdominal pain, breathlessness Bleeding and other side effects.
Necessary symptomatic treatment, in particular, gastric lavage, sorbents. There is no specific antidote.
Cooperation
In the treatment of any other drugs together with Flamaksom be sure before starting therapy consult your doctor.
If both appointed and Flamaks loop diuretics , Increased nephrotoxic effect of these drugs. Flamaks urikozuricheskih reduces the effectiveness of drugs, but enhances the effect of anticoagulants . ethanol . fibrinolitikov . antiplatelet agents As well as the manifestation of side effects while taking corticosteroids and mineralokortikosteroidov . estrogen .
Flamaks reduces the efficiency of the effect of antihypertensive drugs and diuretics.
Together with the application GCS , Other NSAIDs . corticotropin . ethanol possible manifestation of gastrointestinal bleeding, ulcers, impaired renal function.
The risk of bleeding is increased when taken with Heparin . anticoagulants . thrombolytic . antiplatelet . cefoperazone . Tsefamandol . tsefotetanom .
When treating Flamaksom follows to recalculate dose of insulin or other hypoglycemic agents, as their hypoglycemic action increases.
Simultaneous treatment with reception sodium valproate leads to a reduction of platelet aggregation.
Increases concentration nifedipine . verapamil , Drugs, lithium, Methotrexate in blood plasma.
Increases haematotoxicity myelotoxicity funds.
The absorption of the drug is reduced while taking cholestyramine and antacids.
When mixed in a single vial Tramadol Flamaksa and a precipitate formed.
Terms of sale
Flamaks and Flamaks Forte realized prescription.
Storage conditions
Keep Flamaks should be in a dark, dry place, the temperature should not exceed 25 ° C. The tool should be protected from children.
Shelf life
Store medicines can be 3 years.
Cautions
If both untreated and means Flamaks Warfarin or lithium preparations It requires strict monitoring by the physician.
Flamaks may mask the symptoms of infectious diseases.
In the course of therapy, it is important to control the parameters of the peripheral blood and the activity of the liver and kidneys. If their function is impaired, it is necessary to reduce the dose and be closely monitored for the patient.
To reduce the risk of side effects from the gastrointestinal tract, it is necessary to use the minimum dose of the drug and did not practice long-term treatment.
If you have to define 17-ketosteroids , Flamaks canceled 48 hours prior to the study.
It is important to bear in mind that the treatment agent may deteriorate focus, so care should be taken to drive traffic and perform other potentially dangerous operation.
Analogs
Bonifen
Inflexion
Novigan
Deksalgin
Ibuklin
Brufen
Ibuprofen
Nurofen
Analogs Flamaks and Flamaks Forte Which are realized in pharmacies are drugs Ketonal . Inflexion . Artrozilen . Ketosprey . Ketonal uno . Arketal . Artrum . Profenid and etc.
All the analogs have the same effect on the organism, as well as Flamaks But the final decision on the choice of the drug should be taken only by a doctor.
Babies
Not used to treat children under 15 years of age.
During pregnancy and lactation
Do not use Flamaks to treat women in the third trimester of pregnancy and during lactation. If necessary, possible treatment means in the first and second trimesters, but only if the expected benefits outweigh the risk to the fetus.
Reviews Flamaks
In general, reviews of Flamaks and reviews of Flamaks Forte positive. There they pronounced analgesic effect. Often these drugs are used in the postoperative period. Patients say the injections and tablets Flamaks can significantly alleviate the condition after surgery.
It is also a means of widely used by patients in the treatment of pain caused by diseases of the musculoskeletal system. On the manifestation of negative side effects are rarely mentioned in a review.
Price Flamaksa where to buy
Cost ampoules Flamaks an average of 120 rubles. 5 pieces per package. Price capsules - 100-120 rub. 25 pieces per pack. Cost Flamaks Forte is 120-150 rubles. (tablets per pack 20 pcs.).
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