Claritin

Description overdue on 16.12.2011

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The drug allergy. Mainly active substance acts Loratadine . The mechanism of action based on blockade of histamine H1 receptors over time. Claritin inhibits the synthesis of leukotriene C4 and histamine from mast cells , Thereby facilitating the allergic reactions. Loratadine has expressed protivoekssudativnoe, antipruritic, antiallergic. Under its influence in the body decreases smooth muscle spasm, prevents the development of edema, reduced capillary permeability . Preparation action begins after half an hour, the maximum effect is recorded in 12 hours, last night. Claritin not penetrate blood-brain barrier , Non-addictive, it has no effect on the nervous system. The drug does not potentiate the effect of alcohol, it has no anticholinergic effects . The effectiveness of loratadine is independent of food intake. Produced in tablet form and in the form of suspensions and syrup for internal application.

Indications:

Claritin is indicated for the relief of attacks of allergic rhinitis (year-round, seasonal), allergic conjunctivitis, hives   in acute and chronic periods of flow. The drug is effective in angioedema Allergies to insect bites, skin allergies. Actively used in the treatment of chronic eczema , Contact allergic dermatitis, itching dermatoses .

Contraindications:

Claritin is contraindicated during breastfeeding, hypersensitive to loratadine. Be wary appoint hepatic insufficiency system during pregnancy.

Side effects and overdose:

The drug Claritin may be accompanied by fatigue, headaches, gastritis, drowsiness, dry mouth, alopecia . anaphylaxis , Violation of the hepatic system. Children develop sedation , Nervous excitability. If overdose is registered tachycardia , Somnolence, increased severity of side effects. Recommended active gastric lavage. Treatment posindromnoe.

Mode of application:

Claritin adults administered in a dosage of 10 mg once daily. For children weighing less than 30 kg is recommended to receive 5 mg of the drug per day. When hepatic insufficiency systems receive 5 mg per day.

Special instructions:

Claritin affect the driving, the management of complex mechanisms, reduces the rate of reaction in the performance of work requiring speed and attention. Erythromycin . ketoconazole   and other inhibitors SYR3A4, SYR2D6 (e.g. cimetidine ) Increase the level of drug in the body. Tricyclic antidepressants, phenylbutazone . rifampicin , Barbiturates, ethanol, phenytoin, and all inductors of microsomal oxidation negatively affect the efficacy of the drug Claritin. The drug is recommended to be stored at a temperature of + 2-10 degrees Celsius, away from heat, light. Keep away from children.