Description overdue on 04/08/2014
- Latin name: Norbactin
- ATC code: J01MA06
- Active substance: Norfloxacin (Norfloxacinum)
- Manufacturer: Ranbaxy (India)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Norbaktina
- Contraindications
- Side effects
- Instructions for use Norbaktina
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Reviews
- Price, where to buy
Composition
The main active ingredient of the drug - norfloxacin .
Supporting components Norbaktina following: MCC . sodium lauryl . colloidal silicon dioxide . Purified talc . Croscarmellose sodium . corn starch . magnesium stearate .
Valium Purified talc, purified water, macrogol 400 and titanium dioxide.
Product form
The drug is available in tablets.
Pharmacological action
The antibacterial agent. It has a wide range of actions.
Pharmacodynamics and pharmacokinetics
Once in the body, the drug effect on the bacterial enzyme DNA gyrase. The bactericidal effect is quite fast. Development plazmidooposredovannoy resistance minimal.
The drug affects the majority of aerobic gram-negative microorganisms, as well as some gram-positive. This potent antipseudomonal means .
The drug is well absorbed from the gastrointestinal tract. However, it should not be taken with meals, as it reduces its effectiveness. For a better assimilation it is necessary to use an empty stomach.
The maximum concentration of the drug - 1-2 hours after ingestion. Protein binding - 14%. It is widely distributed in tissues, but does not penetrate into the bone and central nervous system. Bioavailability - about 40%, half-life - 3, 5-6, 5 hours, but the high concentrations found in tissues and longer.
The drug is partially processed in the liver. In a certain amount excreted in the bile, but mainly with urine and feces.
Indications Norbaktina
It is used when Norbaktin cystitis . pyelonephritis . urethritis As well as bacterial infections gastrointestinal, genital organs and uncomplicated gonorrhea :
- prostatitis ;
- endometritis ;
- cervicitis ;
- salmonellosis ;
- shigellosis .
Indications Norbaktina also provide for its use by patients with granulocytopenia and travelers' diarrhea as a preventive measure.
Contraindications
The drug should not be taken for those who have observed hypersensitivity to its components, as well as in patients with severe renal failure and pregnant .
Side effects
Norbaktin usually well tolerated. sleepiness and appearance headache . allergic reactions .
Instructions for use Norbaktina
If the patient is assigned Norbaktin, instructions for use provide different dosages that depend on what the tablet is used.
- urinary tract infections
- repetitive or chronic infections of the urinary tract Peaking - for a month, and then, if necessary, used 400 mg per day up to 12 weeks;
- chemoprophylaxis before and after urological surgery;
- intestinal infections - Within 5 days;
- acute uncomplicated cystitis - For 3 days.
400 mg once a day is prescribed, if the indications for use Norbaktina following:
- prevention traveler's diarrhea ;
- renal failure .
In acute uncomplicated gonococcal infection Instructions for use Norbaktina includes receiving 800 mg once daily.
Overdose
dizziness . vomiting . cold sweat . nausea . drowsiness And puffy face without major changes hemodynamic .
As the treatment prescribed gastric lavage and adequate with uprated diuresis . In addition, it is necessary inspection and maintenance in a hospital under the supervision of specialists in a few days.
Cooperation
Assimilation difficult to use Norbaktina antacids Which contain aluminum and magnesium, and iron preparations, sucralfate and zinc. Between their application shall be not less than 4 hours.
In addition, the tool reduces theophylline clearance and the effect of nitrofurans And increases the content of indirect anticoagulants and cyclosporine in serum.
The drug should be taken with caution in conjunction with means that reduce the seizure threshold, otherwise it may cause epileptiform seizures .
Simultaneous reception Norbaktina and means of reducing Blood pressure It may cause an abrupt reduction. So, heart rate and ECG readings should be clearly monitored.
Terms of sale
Tool available on medical prescription.
Storage conditions
The drug should be stored in a dry place at temperatures no higher than 25 ° C.
Shelf life
Norbaktin should be stored no longer than three years.
Analogs Norbaktina
Floratsid
Glewe
Avelox
Fleksid
Levolet P
Tsiprinol
Ofloksin
Tavanic
Nolitsin
Ofloxacin
Pharmacies can get these analogues Norbaktina:
- ;
- Norfloxacin ;
- Normaks .
Their value can be different. The cheapest means considered Norfloxacin . Price Norbaktina but also very affordable.
Reviews Norbaktine
Numerous reviews of Norbaktine indicate that the drug in most cases turns out to be truly effective. On the forums, many ask, is an antibiotic or not, as some contraindicated receiving such funds. However, those who have already tried the drug, noted his performance.
Side effects Norbaktine reviews about almost not reported. There is information about the appearance of a minor Heartburn and other problems with the digestive tract, but the symptoms pass quickly at lower dosages. Reviews of doctors on the tool as mostly positive.
Price Norbaktina
Price Norbaktina is about 90 rubles. This is an inexpensive and affordable, which, according to reviews, is quite effective.
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