- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on DELUFEN (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- For children
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
100 ml of a nasal spray contains the following active ingredients:
- black mustard (Sinapis nigra) D2 - 1 ml;
- latex resiniferous milkweed (Euphorbium) D6 - 10 ml;
- meadow chamber (Pulsatilla) D6- 10 ml;
- luffa (Luffa) - 10 ml;
- mercury diiodide (Mercurius bijodatus) - 10 ml.
As auxiliaries are the following chemicals:
- benzalkonium chloride 0, 01%;
- isotonic sodium chloride (0, 9%).
Product form
Nasal Spray - Transparent colorless liquid odorless and tasteless plastic, polyethylene bottles of 20 ml with a spray-dispenser. The carton is put 1 bottle accommodating the drug.
Pharmacological action
DELUFEN - drug containing the active homeopathic ingredients vegetable origin. The pharmaceutical formulation has the following therapeutic effects:
- anti-inflammatory;
- antimicrobial;
- antiallergic;
- decongestant;
- reparative.
Nasal spray mechanism of action is to reduce the sensitivity of the internal mucosa of the nasal cavity, and it moves to the paranasal sinuses allergens external origin (eg, tobacco smoke, a sharp unpleasant odor, pollen, pet hair and household dust) and endogenous stimuli . Reduces the possibility of a pathological agents exudation That leads to the elimination of the edematous phase of the inflammatory process (largely reduces the risk of septic complications different disease entities). Also regulated secretory function glands of the mucous membrane, thus facilitating nasal breathing, nasal passages from releasing excessive amounts of mucus, and excess endogenous secrets.
Spray for nasal application exhibits antiseptic properties, destroying harmful microorganisms intensifying immune processes in the nasal mucosa. Because the active ingredients contribute moderately moist inner layers of the nasal passages, improving their own defenses.
The pharmaceutical preparation does not cause tachyphylaxis That is, long-term use of the drug during the course of conservative readjustment does not reduce the effectiveness of the therapeutic properties and does not cause addiction or drug dependence.
Pharmacodynamics and pharmacokinetics
Preparation DELUFEN - is multicomponent drug complex, most of whose components are vegetable origin . Because conducting reliable clinical pharmacokinetic studies faculties spray is not possible. It is also impossible to monitor biological markers of active metabolites of active ingredients.
Indications
- various ENT diseases ;
- sinusitis ;
- pharyngitis ;
- evstahiity - Inflammatory diseases of the eustachian tube ( salpingitis );
- rhinitis various origin (including nasal allergy or hay fever );
- pollen disease .
Contraindications
- Increased individual sensitivity to existing components of the drug;
- acquired or hereditary intolerance to the ingredients of a pharmaceutical preparation;
- thyroid disease Manifested enhanced production of thyroid hormones ( hyperthyroidism ).
Side effects
As a rule, the pharmaceutical tolerated favorably, without causing side effects in the course of medical treatment, but the clinical literature describes theoretically possible negative aspects of the therapeutic effects that occur normally and are not cause for rejection of conservative readjustment:
- Increased secretion of the glands of the mucous membrane of the nasal passages;
- Reinforced ptyalism ( salivation );
- sero-mucosal release from the nasal cavity.
Instructions on DELUFEN (method and dosage)
DELUFEN used intranasally , I.e. the drug is delivered directly to the nasal cavity for effective interaction with the mucosa. The nasal passages should be cleaned prior to use of the pharmaceutical preparation, as therapeutic properties are largely more efficient (especially if kids use the aerosol, as the nasal cavity of patients younger category may contain a large number of exogenous particles or allergens).
Method of use:
- remove the protective cap from the vial for containing medicament;
- repeatedly press the sprayer until the first spray (to achieve a uniform spread of the aerosol);
- enter the tip of the bottle in the nasal passage and inject the drug.
Nasal spray dosage depends on the age group of patients:
- for children from 1 to 12 years - 1 injection into each nostril four times a day;
- adults and children to achieve 12 years - 2 injection into each nostril four times a day.
Spray DELUFEN, instructions for use in various pathological conditions (under appropriate medical indications course of conservative treatment can be repeated, as the pharmaceutical preparation does not cause addiction or tachyphylaxis):
- sharp catarrhal rhinitis - 1 week;
- sinusitis sinuses . evstahiit . purulent rhinitis - 2-4 weeks, depending on the efficacy of therapy in the early stages of rehabilitation conservative;
- chronic, sluggish rhinitis - 4-8 weeks;
- pollen disease . hay fever or nasal allergy - 1-4 weeks (the duration of a course of drug treatment depends on the duration of a provoking factor).
Overdose
According to overdose of pharmaceuticals in the process of conservative treatment has not yet been registered.
Cooperation
Clinically significant interactions nasal spray with other drugs in the medical literature is not described.
Terms of sale
Nasal spray is approved for use without a corresponding form of the receptor.
Storage conditions
The drug should be stored out of direct sunlight and away from children younger place. Away from strong electromagnetic fields under constant temperature conditions not exceeding 25 degrees Celsius.
Shelf life
5 years (after the first application of the drug vial can be used only for the first two months).
Cautions
The main active components of the nasal spray are vegetable natural substances Because long-term storage of the drug possible drug haze of the liquid inside the bottle. However, this change does not have the transparency of any clinical consequences, and therefore does not lead to a decrease in therapeutic effects.
Analogs
Match code ATC 4th level: The drug is very popular in the pharmaceutical market, especially among young mothers, as analogues of the nasal spray are a relatively large number of drugs: Adelfan (usually, when any contraindications to the use DELUFEN used this medication since it is a combination of three active ingredients: reserpine . digidralazina and hydrochlorothiazide ) Enap . Trirezid . Reserpine .
For children
The drug may be used in pediatric patients after the child reaches the age of 1 year. Instructions for use of the pharmaceutical preparation for children does not differ from that of adult patients.
Separately, it should be noted that the drug is highly effective for children reviews that you can find a little bit lower, as during adolescence is the formation of the normal structure of the mucosa of the nasal cavity and paranasal sinuses. Thanks to Healing properties of nasal spray strengthens its resistance and the ability to take an active protective function with respect to the exogenous and endogenous stimuli.
DELUFEN during pregnancy and lactation
Pharmacokinetic DELUFEN ability can not be reliably studied, because the use of the drug during breastfeeding and during pregnancy is solved with the doctor individually.
Reviews Delufene
Delufene reviews are mostly positive. In a relatively short period of time (with a favorable course of conservative therapy maximum duration of medication course is only 4 weeks) a drug eliminates the pathologies that significantly reduce quality of life. Eliminated the problem of over-abundant rhinorrhea Since it eliminated the action of provoking factors, and docked exudative phase of the inflammatory focus.
Separately, it is worth noting the recommendations for children. Nasal Spray is very popular among young mothers, as most young children are extremely active and very often find themselves in the ENT department of diseases of exogenous etiology (penetration of allergens, foreign bodies, excessive discharge from the nose).
Active use of the pharmaceutical in the critical periods for a woman is a frequent topic of lengthy discussions at medical conferences related to the upper respiratory tract disease because the reviews during pregnancy or while breast-feeding so few in the discussion forums and Internet resources.
Price DELUFEN where to buy
Price DELUFEN spray on the territory of the Russian Federation varies from 210 to 280 rubles. The cost of a pharmaceutical formulation in Ukraine, as a rule, somewhat higher. For example, the price DELUFEN in Kharkov is around 100 hryvnia.
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