Description overdue on 05/22/2014
- Latin name: Polydexa with Phenylephrine
- ATC code: R01AD53
- Active substance: Dexamethasone + Neomycin Polymyxin B + B + Phenylephrine (Dexamethasone + Neomycin + Polymyxin B + Phenylephrine)
- Manufacturer: GP Grenzach Produktions (Germany)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- C antibiotics
- Reviews
- Price, where to buy
Composition
Spray Valium has in the composition neomycin sulfate . polymyxin B sulfate . Dexamethasone metasulfobenzoat sodium . phenylephrine hydrochloride . In addition, the preparation contains additional substances: lithium chloride . methyl parahydroxybenzoate . citric acid . macrogol 400 . lithium hydroxide . polysorbate . water .
Product form
The drug is available in the form a spray. It is a colorless transparent liquid, which is contained in a bottle made of polyethylene with a sprayer. Vial contains 15 ml of the preparation, it is packaged in a pack made of cardboard.
Pharmacological action
Combined drug that is used in otorhinolaryngology for local use. Polydex with phenylephrine It has anti-inflammatory action due to the impact of Dexamethasone on mucous nose. Phenylephrine It has vasoconstrictor effect, and antibiotics neomycin and Polymyxin B stipulate antibacterial influence. The combination of antibiotics allows you to expand the range of their actions. Therefore, these drops in the nose with an antibiotic effect on most gram-positive and gram-negative organisms that provoke the development of infectious and inflammatory diseases of the nasal cavity and paranasal sinuses.
Pharmacodynamics and pharmacokinetics
No data on the pharmacokinetics of the drug due to its low systemic absorption.
Indications
Nasal drops (spray) Polydex with phenylephrine should be used to treat infectious and inflammatory diseases of the nasal cavity, paranasal sinuses and nasopharynx:
- acute and chronic suppurative rhinitis ;
- genyantritis . sinusitis . sinusitis ;
- acute and chronic nasopharyngitis ;
- chronic adenoiditis ;
- purulent rhinitis in children, as a consequence of prolonged intubation, nasotracheal way;
- prevention and treatment of after surgical operations on the the nasal cavity and of adnexal or additional the axils of.
Contraindications
Not applicable Polydex nasal spray in the following diseases and conditions:
- High sensitivity to the product;
- suspected development of closure Glaucoma ;
- application MAO inhibitors ;
- kidney At which the notes albuminuria .
Precautions should use the drug if the patient has symptoms hyperthyroidism At hypertensive disease . angina . coronary heart disease .
Side effects
Perhaps the manifestation of the following side effects while taking the drug. Polydex nose in some cases, may provoke a feeling of dryness in the nose, as well as a manifestation of allergic reactions - itching . skin rashes . hives . Nasal medication causes systemic side effect only when it is used for long-term treatment, or if it is used at a dose which is much higher than recommended. As the systemic side effects may be a manifestation of headache, tremor . tachycardia , Pale skin, high blood pressure, insomnia .
Instructions for use (method and dosage)
If you are used Polydex nose drops with phenylephrine , Instructions should be taken into account. Adult patients should use a nose spray in the following manner: from 3 to 5 times a day performed one injection into each nasal passage.
Instructions for use nasal spray Children of 12 years provides a maximum of 3 injections per day funds in each nostril.
The treatment lasts from 5 to 10 days. To make the injection, you need to click on the bottle. It should be kept upright, with the head must be slightly tilted forward, so that the solution got into the nasal passage in a spray rather than a trickle of fluid. It held only one press of the injection.
If within 10 days of improvement is not observed, you must consult your doctor and stop the treatment drug.
Do not use the drug for the purpose of washing the nasal sinuses. Polydex at sinusitis - Is the drug of choice, experts say that it should be used strictly according to instructions. Reviews in the sinus indicate that the effect of the agent depends on the individual.
Overdose
When applied topically, can not overdose, as absorption agents in their local application is very low.
Cooperation
Nasal spray for children and adults Polydex often used in the combined treatment because of good compatibility with other drugs. However, some drugs Polydex not combined.
- When combined with Bromocriptine increased risk of symptoms of hypertension.
- When combined with Guanethidine hypertensive amplifies the effect of phenylephrine.
- When combined with MAO inhibitors hypertensive patients increases the risk of hypertensive crisis .
- Do not combine the drug and treatment selective MAO inhibitors in connection with absence accurate information about the such an interaction.
- Using Halothane or Cyclopropane together with the increased risk of Polydex ventricular fibrillation .
- Possible negative effects on cardiac function when combining the drug with Bepridilom . Halofantrine . Sparfloxacin . Aminoglutethimide . Terfenadine sultopride . Erythromycin . Vincamine . Astemizole . Pentamidine .
In addition, care must be taken with a long reception funds from Acetylsalicylic acid And other salicylates, as well as antiarrhythmic drugs .
Particular care is needed when combined with Polydex attenuated live vaccines, since there is a high probability of the generalization of the disease.
Terms of sale
A preparation in the a network of drugstores released under the prescription.
Storage conditions
Refers to the list of AB should be stored at a temperature of the drug to 25 ° C, keep away from the reach of children.
Shelf life
The product can be stored for 3 years.
Cautions
Polydex drug can not be taken inside. Should not practice means treatment for longer than 10 days, since there is a risk of withdrawal and iatrogenic rhinitis . When long-term therapy or in the use of high doses it can exert systemic effects on the body.
In view of the presence in the Polydex Corticosteroid It may change during the allergy, but its local symptoms do not disappear.
The drug contains dexamethasone Which is in the process of doping control can give a positive result.
After the drug vial opened, there is the possibility of contamination by microorganisms.
Case, the effect on the ability to drive vehicles and operate the exact mechanisms are not noted.
Analogs Polydex with phenylephrine
Tafen Nazal
Nasobek
Avamys
Fliksonaze
Nasonex
Nazarel
Bekonaze
In drugstores are realized some analogues of nasal spray, having similar influence on an organism. A similar structure is seen in drugs Maksitrol . However, this means - not an analogue middle nose, as it is used in ophthalmology.
Is it better or Polydex Izofra?
What it means - Izofra or Polydex for adults and children is the best, in each case only an expert can tell. As part of the preparation Izofra - framycetin sulfate Antibiotic, which belongs to the same group as that of the antibiotic composition Polydex. To accurately determine the effectiveness of both the funds necessary to carry out bacterial inoculation test to obtain information about the susceptibility of microorganisms to each of the antibiotics.
Is it better or Rinofluimutsil Polydex?
Rinofluimutsil It is composed of acetylcysteine and tuaminoheptane It has vasoconstrictor, anti mucolytic, antioxidant action. However, this means, unlike Polydex has no antibiotic in the composition.
Babies
Polydex used in the treatment of children runny nose . sinusitis . sinusitis . However, in the instructions it is that the drug can be used in the treatment of children with only 12 years of age.
Treatment for young children is possible only under the strict supervision of a specialist and carefully all the recommendations for use.
During pregnancy and lactation
To date, there are no reliable studies about the impact of Polydex on the body of the pregnant woman and the fetus. There is evidence that long-term use of the drug is possible ototoxic effect on the fetus, which ultimately can cause malformation of the ear.
The drug is given in some cases, during pregnancy only after careful weighing of the expected benefits and harmful effects. Whenever possible, the doctor prescribes the treatment of other drugs.
With Lactation Polydex the period of treatment should stop breastfeeding.
C antibiotics
Nasal Spray can not be combined with antibiotics Gentamicin . Streptomycin . Netilmicin . Amikacin . Monomitsin As likely to strengthen Valium action.
Reviews Polydex with phenylephrine
Reviews of nasal spray Polydex evidence of its effectiveness as a means of preparation is considered to be a new generation. It is noted that the nasal spray is often the patient's condition improves after a few uses.
There are reviews nasal drops Where the point is that the drug helped reduce the intensity of pain in the maxillary sinus, headaches, swelling. However, it is noted that the application of the tools you need to carefully follow the instructions and use it only as recommended by a doctor. The review found the negative comments about the inconvenience of using a bottle.
Price Polydex with phenylephrine, where to buy
Cost Polydex nasal spray with phenylephrine 15 ml of an average of 230-260 rubles. Nasal spray may have a different value depending on the pharmacy in which it is implemented. Cost nose drops Polydex Ukraine is an average of 80 - 100 UAH.
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