Kandizol

Description overdue on 10/17/2013

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Antifungal medications.   It is active against pathogens erythrasma, tinea versicolor. The current component has a fungicidal effect of high concentrations and fungistatic - small. The mechanism of action is based on the reduction of the output ergosterol Which is the main structural cell membrane of the microorganism. The active substance is one of the imidazole derivatives. Clotrimazole can be applied externally and intravaginally (local effects). At high concentrations of the active substance reacts with the peroxidase and substances mitochondrial enzymes, increasing the hydrogen peroxide concentration to maximum performance for the toxic fungal cells. The drug affects the Gram-positive flora , Gram-negative bacteria against fungi (yeasts, molds) for pathogenic dermatophyte. Kandizol produced in the form of a cream (for vaginal and topical), solution, tablets (vaginal form) powder.

Indications:

Kandizol ointment prescribed for tinea , Microsporia, erythrasma, mycosis, candidiasis , Athlete, trihofitii, colorful herpes, ringworm, balanitis, pityriasis versicolor, fungal paronychia erosion and interdigital spaces. Kandizol capsule administered vaginally for trichomoniasis, vulvovaginal , Candidiasis of the vulva. The drug is administered before delivery for the redevelopment of the birth canal of women.

Contraindications:

Clotrimazole is not indicated in the first trimester of pregnancy, individual hypersensitivity to active ingredients. When breastfeeding clotrimazole medicine used with caution when evaluating risks. Kandizol tablets are not recommended to enter during menstruation.

Side effect:

Kandizol ointment in intravaginal administration can cause a burning sensation. Rarely observed erythematous reactions , Paresthesia, peeling of the skin, swelling, blisters. The treatment clotrimazole are frequent urge to urinate, vaginal discharge, cystitis (intercurrent form) stomachalgia , Headaches, pain during sexual intercourse, a burning sensation in the penis in a partner.

Mode of application:

Solution, ointment, cream and lotion is applied to the thin layer of skin 2-3 times a day. The drug can be rubbed with light circular movements. On the palm-sized portions is applied 10-20 drops of clotrimazole or 5 mm column cream from a tube. The duration of antifungal therapy - 1 month. Instructions for use Kandizola recommends to continue the treatment for 14 days after the disappearance of the fungal disease. Therapy multi-colored lichen takes about 3 weeks, erythrasma - 30 days. Before applying the medication skin thoroughly washed with warm water (preferably soapy water), wipe with a towel, paying special attention to spaces between the toes. Treatment of fungal skin legs continued for 2-3 weeks after the therapeutic effect. Kandizol capsule administered 5 grams of 1 times a day intravaginal deeply. The course lasts for 3 days. Before delivery for the redevelopment of the birth canal   1 times 1 tablet administered clotrimazole. Treatment of urethritis : Sixfold instillation into the urethra of the solution concentration of 1% with an interval of 24 hours. Kandizol tablets at Candida vulvitis   1 is administered once at a dose of 500 mg or 200 mg for three days. Treatment of balanitis and vulvitis fungal origin must necessarily involve the processing of the external genitalia with a concentrated solution, cream. Price Kandizol depends on the form of the issue (100-200 rubles).

Special instructions:

Patients with abnormal liver system is carried out biochemical blood (shown enzyme ALT, AST). Prevention   reinfection   achieved by simultaneous treatment of sexual partners. Do not use vaginal applicators during pregnancy. It is necessary to protect the mucous membranes of the eyes when applied clotrimazole. Do not apply an occlusive dressing. Antifungal therapy discontinued if irritation or allergic response. In the absence of positive dynamics in the period of 30 days is recommended to perform additional diagnostic methods for the detection of the pathogen. Treatment of trichomoniasis includes oral metronidazole.

Drug Interactions:

The effectiveness of the treatment decreases Kandizola nystatin, amphotericin B and natamycin.